Kevin Plawecki hit his first career grand slam during a nine-run sixth inning, Brandon Nimmo went 5 for 5 with three RBIs and the New York Mets breezed past the Baltimore Orioles 16-5 on Wednesday night.

Todd Frazier homered and drove in four runs to help the Mets earn a split of the two-game interleague series. New York finished 1-3 this season against the Orioles, who own the worst record in the majors.

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New York Mets' Brandon Nimmo watches his two-run triple in front of Baltimore Orioles catcher Austin Wynns during the sixth inning of a baseball game Wednesday, Aug. 15, 2018, in Baltimore. (AP PhotoPatrick Semansky)

Kevin Plawecki hit his first career grand slam during a nine-run sixth inning, Brandon Nimmo went 5 for 5 with three RBIs and the New York Mets breezed past the Baltimore Orioles 16-5 on Wednesday night.

New York Mets' Wilmer Flores watches an RBI sacrifice fly during the first inning against the Baltimore Orioles in a baseball game Wednesday, Aug. 15, 2018, in Baltimore. (AP PhotoPatrick Semansky)

Zack Wheeler (8-6) gave up one run and five hits over five innings to win his sixth straight start. The right-hander was removed from the game by manager Mickey Callaway after the Mets sent 12 batters to the plate in a lengthy sixth against Dylan Bundy (7-11) and three relievers.

Baltimore Orioles starting pitcher Dylan Bundy throws to a New York Mets batter during the first inning of a baseball game Wednesday, Aug. 15, 2018, in Baltimore. (AP PhotoPatrick Semansky)

That made it 14-1, and the only remaining suspense was whether Nimmo could hit for the cycle after going single, double, double, triple in his first four at-bats. He was hit by a pitch in the seventh inning and singled in the ninth, giving him a career-high five hits.

New York Mets starter Zack Wheeler follows through on a pitch to the Baltimore Orioles during the second inning of a baseball game Wednesday, Aug. 15, 2018, in Baltimore. (AP PhotoPatrick Semansky)

Mets: David Wright (shoulder/back) went 0 for 3 and played 3B for Class A St. Lucie and is hitless in three rehab games. He has not played a major league game since May 2016. ... Jay Bruce (sore right hip) played 1B and went 2 for 4 for St. Lucie. He has been on the DL since June 18.

Baltimore Orioles manager Buck Showalter watches from the dugout, with New York Mets catcher Kevin Plawecki in the foreground, during the first inning of a baseball game Wednesday, Aug. 15, 2018, in Baltimore. (AP PhotoPatrick Semansky)

Conforto missed all of spring training after undergoing shoulder surgery last September.

New York Mets' Jeff McNeil, center, high-fives teammates in the dugout after scoring on Todd Frazier's single during the first inning of a baseball game against the Baltimore Orioles, Wednesday, Aug. 15, 2018, in Baltimore. (AP PhotoPatrick Semansky)

Mets: It's up to Philadelphia for a single-admission doubleheader on Thursday. Corey Oswalt (1-2) will start the opener followed by Steven Matz (1-2), who's been on the DL with a strained left arm. He will be limited to 80 pitches, Callaway said.

Baltimore Orioles' Adam Jones follows through on an RBI single in front of New York Mets catcher Kevin Plawecki during the first inning of a baseball game Wednesday, Aug. 15, 2018, in Baltimore. (AP PhotoPatrick Semansky)

Baltimore Orioles' Adam Jones follows through on an RBI single in front of New York Mets catcher Kevin Plawecki during the first inning of a baseball game Wednesday, Aug. 15, 2018, in Baltimore. (AP PhotoPatrick Semansky)

Baltimore Orioles' Mark Trumbo, right, greets Jonathan Villar after Villar scored on Adam Jones' single during the first inning of a baseball game against the New York Mets, Wednesday, Aug. 15, 2018, in Baltimore. (AP PhotoPatrick Semansky)

Baltimore Orioles' Mark Trumbo, right, greets Jonathan Villar after Villar scored on Adam Jones' single during the first inning of a baseball game against the New York Mets, Wednesday, Aug. 15, 2018, in Baltimore. (AP PhotoPatrick Semansky)

A home run by Wilmer Flores in the ninth enabled the Mets to reach a season high in runs.

New York Mets' Brandon Nimmo watches his two-run triple in front of Baltimore Orioles catcher Austin Wynns during the sixth inning of a baseball game Wednesday, Aug. 15, 2018, in Baltimore. (AP PhotoPatrick Semansky)

New York Mets' Brandon Nimmo watches his two-run triple in front of Baltimore Orioles catcher Austin Wynns during the sixth inning of a baseball game Wednesday, Aug. 15, 2018, in Baltimore. (AP PhotoPatrick Semansky)

Zack Wheeler (8-6) gave up one run and five hits over five innings to win his sixth straight start. The right-hander was removed from the game by manager Mickey Callaway after the Mets sent 12 batters to the plate in a lengthy sixth against Dylan Bundy (7-11) and three relievers.

After Bundy left with two on, Nimmo hit a two-run triple. A wild pitch let in a run and Frazier doubled in two runs before right-hander Evan Phillips issued a pair of walks to load the bases for Plawecki.

Phillips fell behind in the count before grooving a fastball that Plawecki smacked into the left-field seats. It was only his 11th home run in 205 games over four seasons.

New York Mets' Wilmer Flores watches an RBI sacrifice fly during the first inning against the Baltimore Orioles in a baseball game Wednesday, Aug. 15, 2018, in Baltimore. (AP PhotoPatrick Semansky)

New York Mets' Wilmer Flores watches an RBI sacrifice fly during the first inning against the Baltimore Orioles in a baseball game Wednesday, Aug. 15, 2018, in Baltimore. (AP PhotoPatrick Semansky)

That made it 14-1, and the only remaining suspense was whether Nimmo could hit for the cycle after going single, double, double, triple in his first four at-bats. He was hit by a pitch in the seventh inning and singled in the ninth, giving him a career-high five hits.

In the eighth, Mets backup third baseman Jack Reinheimer got his first major league hit, a single up the middle off Cody Carroll.

TRAINER'S ROOM

Baltimore Orioles starting pitcher Dylan Bundy throws to a New York Mets batter during the first inning of a baseball game Wednesday, Aug. 15, 2018, in Baltimore. (AP PhotoPatrick Semansky)

Baltimore Orioles starting pitcher Dylan Bundy throws to a New York Mets batter during the first inning of a baseball game Wednesday, Aug. 15, 2018, in Baltimore. (AP PhotoPatrick Semansky)

Mets: David Wright (shoulder/back) went 0 for 3 and played 3B for Class A St. Lucie and is hitless in three rehab games. He has not played a major league game since May 2016. ... Jay Bruce (sore right hip) played 1B and went 2 for 4 for St. Lucie. He has been on the DL since June 18.

COMFORTABLE CONFORTO

Though Mets CF Michael Conforto went 1 for 8 with five strikeouts in the series, he's batting .299 since the All-Star break.

New York Mets starter Zack Wheeler follows through on a pitch to the Baltimore Orioles during the second inning of a baseball game Wednesday, Aug. 15, 2018, in Baltimore. (AP PhotoPatrick Semansky)

New York Mets starter Zack Wheeler follows through on a pitch to the Baltimore Orioles during the second inning of a baseball game Wednesday, Aug. 15, 2018, in Baltimore. (AP PhotoPatrick Semansky)

Conforto missed all of spring training after undergoing shoulder surgery last September.

"I think that he's finally finding more of a comfort zone," Callaway said. "He's done a great job of settling in, and we're seeing a more consistent Michael Conforto out there every day."

UP NEXT

Baltimore Orioles manager Buck Showalter watches from the dugout, with New York Mets catcher Kevin Plawecki in the foreground, during the first inning of a baseball game Wednesday, Aug. 15, 2018, in Baltimore. (AP PhotoPatrick Semansky)

Baltimore Orioles manager Buck Showalter watches from the dugout, with New York Mets catcher Kevin Plawecki in the foreground, during the first inning of a baseball game Wednesday, Aug. 15, 2018, in Baltimore. (AP PhotoPatrick Semansky)

Mets: It's up to Philadelphia for a single-admission doubleheader on Thursday. Corey Oswalt (1-2) will start the opener followed by Steven Matz (1-2), who's been on the DL with a strained left arm. He will be limited to 80 pitches, Callaway said.

Orioles: A rarity on Thursday for Baltimore, which gets its second day off this week (also Monday). The Orioles open a three-game series in Cleveland on Friday night.

More AP baseball: https://apnews.com/tag/MLBbaseball and https://twitter.com/AP_Sports

New York Mets' Jeff McNeil, center, high-fives teammates in the dugout after scoring on Todd Frazier's single during the first inning of a baseball game against the Baltimore Orioles, Wednesday, Aug. 15, 2018, in Baltimore. (AP PhotoPatrick Semansky)

New York Mets' Jeff McNeil, center, high-fives teammates in the dugout after scoring on Todd Frazier's single during the first inning of a baseball game against the Baltimore Orioles, Wednesday, Aug. 15, 2018, in Baltimore. (AP PhotoPatrick Semansky)

Baltimore Orioles' Adam Jones follows through on an RBI single in front of New York Mets catcher Kevin Plawecki during the first inning of a baseball game Wednesday, Aug. 15, 2018, in Baltimore. (AP PhotoPatrick Semansky)

Baltimore Orioles' Adam Jones follows through on an RBI single in front of New York Mets catcher Kevin Plawecki during the first inning of a baseball game Wednesday, Aug. 15, 2018, in Baltimore. (AP PhotoPatrick Semansky)

Baltimore Orioles' Mark Trumbo, right, greets Jonathan Villar after Villar scored on Adam Jones' single during the first inning of a baseball game against the New York Mets, Wednesday, Aug. 15, 2018, in Baltimore. (AP PhotoPatrick Semansky)

Baltimore Orioles' Mark Trumbo, right, greets Jonathan Villar after Villar scored on Adam Jones' single during the first inning of a baseball game against the New York Mets, Wednesday, Aug. 15, 2018, in Baltimore. (AP PhotoPatrick Semansky)