TOKYO & NEW YORK & DÜSSELDORF, Germany--(BUSINESS WIRE)--May 2, 2024--
Generating cutting-edge therapeutics requires precision, safety, and efficiency from manufacturing equipment. The next generation of oligo manufacturing, the process of producing short sequences of nucleotides (building blocks of DNA or RNA), innovation from Asahi Kasei Bioprocess (AKB), the THESYS™ ACS ERGO synthesis column, will be on display and demonstrated at Booth 213 at TIDES USA 2024 from May 14 th to 17 th at the Hynes Convention Center in Boston. This new synthesis column offers drastically reduced changeover time between batches while maintaining user safety and product quality.
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Following the success of AKB’s DAC ERGO™, a liquid chromatography column, the company has continued advancing column technology with the THESYS™ ACS ERGO. The THESYS ACS ERGO is designed for oligonucleotide synthesis and includes an operator-friendly design to facilitate a smooth and safe changeover between runs. It provides the same reliable high-performance as AKB’s other synthesis columns but is uniquely engineered to reduce inefficiencies between batches – with upwards of an hour of time savings as well as projected labor reduction.
The time-saving features of the THESYS™ ACS ERGO are achieved by eliminating the use of threaded bolts in the changeover and maintenance process, which can be tedious and time-consuming to remove between runs. AKB has ergonomically designed the THESYS™ ACS ERGO for faster changeover without cost to safety, which improves customer efficiency while maintaining operator safety and product reliability.
“Our new, bolt-free design is unique to the column market and makes unpacking and cleaning far less time-consuming,” said Chris Rombach, EVP at Asahi Kasei Bioprocess America (AKBA). “Every feature of the ACS ERGO has been considered, with greater productivity for manufacturers and operator safety as the top priorities.”
THESYS™ ACS includes an innovative I-bar format that makes removing the top of the column more efficient and a unique frame with an integrated gearbox and wheel to facilitate smooth, safe unpacking and cleaning. Furthermore, the column has a minimized footprint to seamlessly integrate into the manufacturing floor.
In addition to its booth at the event, AKB will host a ‘Spotlight Presentation ’ on May 16 at 12:20 p.m. in room 302 about the oligo manufacturing process. Dr. Tom Krebstakies, Sales Manager for Europe and Asia at AKB, will speak about innovations from synthesis through concentration and the applicable equipment considerations for effective technical implementation.
Attendees are invited to visit AKB at Booth 213 to explore new products, witness live demos, and learn more about how AKB’s innovations make manufacturing therapeutics easier.
Learn more about how AKB helps oligo process engineers quickly improve throughput, efficiency, and costs.
About Asahi Kasei Bioprocess
The Fluid Management Business Unit of Asahi Kasei Bioprocess is devoted to solving therapeutic product safety, efficiency, and purity challenges within the pharmaceutical and bioprocessing industries. With technology platforms for oligonucleotide synthesis, buffer formulation, chromatography, and filtration, our bioprocess systems, columns, and automation solutions advance GMP manufacturing of critical drug substances around the world. Built with pride, built with quality, built to exceed expectations. “Built for You.” For more information, please visit https://fluidmgmt.ak-bio.com.
About Asahi Kasei
The Asahi Kasei Group contributes to life and living for people around the world. Since its foundation in 1922 with ammonia and cellulose fiber business, Asahi Kasei has consistently grown through the proactive transformation of its business portfolio to meet the evolving needs of every age. With more than 48,000 employees worldwide, the company contributes to sustainable society by providing solutions to the world’s challenges through its three business sectors of Material, Homes, and Health Care. For more information, visit www.asahi-kasei.com.
Asahi Kasei is also dedicated to sustainability initiatives and is contributing to reaching a carbon neutral society by 2050. To learn more, visit https://www.asahi-kasei.com/sustainability/.
Concept image of the THESYS™ ACS ERGO synthesis column. (Photo: Business Wire)
Slovakia’s Prime Minister Robert Fico was seriously wounded in an apparent assassination attempt just weeks before a Europe-wide election that has been deeply divisive. He was shot multiple times in an attack in the town of Handlova that authorities described as politically motivated, although they said the suspect did not belong to any political groups.
Here’s a global look at other notable assassinations and assassination attempts during the 21st century:
— Sept. 1, 2022: Argentina's then-Vice President Cristina Fernández is targeted by a man who reportedly aimed a handgun at point-blank range toward the politician in what government ministers characterize as an assassination attempt.
— July 8, 2022: Japanese former Prime Minister Shinzo Abe is assassinated by a gunman who opened fire on him as he delivered a campaign speech on a street in western Japan.
— Nov. 6, 2021: Iraqi Prime Minister Mustafa al-Kadhimi survives an assassination attempt when two armed drones target his residence in Baghdad's Green Zone area. While al-Kadhimi is uninjured, seven of his security guards are injured in the attack.
— Oct. 15, 2021: British lawmaker David Amess is stabbed to death by an Islamic State supporter while meeting with voters.
— July 7, 2021: Haitian President Jovenel Moïse is assassinated by gunmen in an overnight raid on his Port-au-Prince home. His widow, Martine, ex-prime minister Claude Joseph and the former chief of Haiti’s National Police, Léon Charles, among others, are indicted in his killing in February 2024.
— April 20, 2021: Chad President Idriss Deby Itno is killed while battling rebels in the north. Hours earlier he had been declared the winner of an election that would have given him another six years in power.
— Aug. 4, 2018: Drones armed with explosives detonate near Venezuelan President Nicolas Maduro in an apparent assassination attempt while he is delivering a speech to hundreds of soldiers being broadcast live on television. Six people are later arrested in connection with the attack.
— Dec. 19, 2016: Russia’s ambassador to Turkey Andrei Karlov is shot dead by a Turkish policeman shouting condemnation of Russia’s military role in Syria, in front of a shocked gathering at a photo exhibit. The gunman was later killed in a shootout with police.
— July 15, 2016: A group of Turkish soldiers using tanks, warplanes and helicopters launch a plot to overthrow Turkey's president and government. The coup attempt fails. One year later, 40 people are sentenced to life in prison after being convicted on charges that include attempting to kill President Recep Tayyip Erdogan.
— June 16, 2016: British lawmaker Jo Cox is shot and stabbed to death by a far-right supporter in the English village of Birstall, part of her constituency.
— Feb. 6, 2013: Tunisian left-wing opposition leader Chokri Belaid is fatally shot outside his Tunis home. His killing — followed six months later by that of another left-wing leader, Mohammed Brahmi — plunged Tunisia into political chaos. Four people are sentenced to death and two others to life in prison in March 2024 for their roles in his death.
— Oct. 20, 2011: Longtime Libyan dictator Moammar Gadhafi is hunted and summarily killed by insurgents after being toppled in a NATO-backed uprising.
— Jan. 8, 2011: U.S. Rep. Gabrielle Giffords survives an assassination attempt after being shot by a man in an Arizona grocery store parking lot while meeting with constituents. Giffords' injuries are so significant that she has to re-learn how to walk and talk. The attack kills six other people and wounds 11 more.
— March 2, 2009: Guinea-Bissau President Joao Bernardo Vieira is killed by renegade soldiers in his palace, hours after a bomb blast killed his rival in the West African nation.
— December 27, 2007: Benazir Bhutto, the first female prime minister in a Muslim-majority country as well as Pakistan’s second nationally elected prime minister, is shot at and then fatally attacked by a suicide bomber at a political rally in Rawalpindi, Pakistan.
— Feb. 14, 2005: Lebanese Prime Minister Rafik Hariri is killed by a suicide truck bomb on a seaside boulevard in Beirut. Another 21 people die and 226 are wounded in the attack, which is seen by many in Lebanon as the work of neighboring Syria.
— March 12, 2003: Serbian Prime Minister Zoran Djindjic is shot dead in front of the Serbian government headquarters in Belgrade. He was a key leader of the revolt that toppled former President Slobodan Milosevic in October 2000. Twelve people are later convicted in connection with the killing, which was carried out to halt his pro-Western reforms, according to a Serbian court ruling.
— July 2, 2002: French President Jacques Chirac survives an assassination attempt by a far-right right supporter who shoots at him and misses during Bastille Day celebrations on Paris' Champs-Elysees. Chirac is uninjured.
— May 6, 2002: Dutch politician Pim Fortuyn is gunned down in a northern Netherlands city, days before a general election in which he was a candidate, by an animal rights activist.
— June 1, 2001: Nepal’s King Birendra is killed when his son, Crown Prince Dipendra, opens fire on his family in the royal palace. The dead include Queen Aiswarya, a prince and five others. Officials said the shooting followed a dispute over the prince’s marriage.
— Jan. 18, 2001: Congo President Laurent Kabila is assassinated in the presidential palace in the capital, Kinshasa, by one of his bodyguards, who is killed minutes later by security forces.
FILE - Supporters of Argentine Vice President Cristina Fernandez gather in Plaza de Mayo square the day after a person pointed a gun at her outside her home in Buenos Aires, Argentina, Friday, Sept. 2, 2022. (AP Photo/Rodrigo Abd, File)
FILE - A police investigator works in a van at the scene where a person pointed a gun at Argentina's Vice President Cristina Fernandez outside her home in the Recoleta neighborhood of Buenos Aires, Argentina, on Sept. 1, 2022. (AP Photo/Natacha Pisarenko, File)
FILE - People pray at a makeshift memorial at the scene where former Prime Minister Shinzo Abe was shot during an election campaign in Nara, western Japan on July 8, 2022. Abe was assassinated by a gunman who opened fire on him as he delivered a campaign speech on a street. (Kyodo News via AP, File)
Rescue workers wheel Slovak Prime Minister Robert Fico, who was shot and injured, to a hospital in the town of Banska Bystrica, central Slovakia, Wednesday, May 15, 2024. (Jan Kroslak/TASR via AP)
Police arrest a man after Slovak Prime Minister Robert Fico was shot and injured following the cabinet's away-from-home session in the town of Handlova, Slovakia, Wednesday, May 15, 2024. Fico is in life-threatening condition after being wounded in a shooting Wednesday afternoon, according to his Facebook profile. (Radovan Stoklasa/TASR via AP)
FILE - Slovakia's Prime Minister Robert Fico speaks during a press conference with Hungary's Prime Minister Viktor Orban at the Carmelite Monastery in Budapest, Hungary, Tuesday, Jan. 16, 2024. Slovakia's populist Prime Minister Robert Fico was wounded in a shooting Wednesday May 15, 2024 and taken to hospital. (AP Photo/Denes Erdos, File)
