Khris Davis hit his second homer of the night leading off the bottom of the 10th inning for career-high No. 45, sending the Oakland Athletics past the Minnesota Twins 7-6 on Friday night.

Davis hit a 1-1 pitch from Matt Magill (3-3) over the fence in right-center for his fourth career walkoff homer. It marked the slugger's 22nd multihomer game and seventh this season.

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Oakland Athletics' Khris Davis, right, celebrates as he passes Minnesota Twins' Ehire Adrianza (16) after hitting a two-run home run off Jose Berrios during the first inning of a baseball game Friday, Sept. 21, 2018, in Oakland, Calif. (AP PhotoBen Margot)

Khris Davis hit his second homer of the night leading off the bottom of the 10th inning for career-high No. 45, sending the Oakland Athletics past the Minnesota Twins 7-6 on Friday night.

Minnesota Twins' Tyler Austin, left, Joe Mauer (7) and Ehire Adrianza celebrate after scoring against the Oakland Athletics during the sixth inning of a baseball game Friday, Sept. 21, 2018, in Oakland, Calif. All scored on a double by Jorge Polanco. (AP PhotoBen Margot)

Pinch-hitter Mark Canha hit a tying two-run homer in the sixth after Minnesota went ahead in the top of the inning.

Minnesota Twins' Robbie Grossman, right, celebrates with Max Kepler after hitting a two-run home run off Oakland Athletics' Lou Trivino during the sixth inning of a baseball game Friday, Sept. 21, 2018, in Oakland, Calif. (AP PhotoBen Margot)

Blake Treinen (8-3) pitched the ninth for the A's, coming off a 21-3 win against the Angels and 31 runs the past two games as they rebounded from a rare three-game losing streak.

Oakland Athletics' Ramon Laureano scores behind Minnesota Twins catcher Willians Astudillo during the second inning of a baseball game Friday, Sept. 21, 2018, in Oakland, Calif. (AP PhotoBen Margot)

Jonathan Lucroy added a sacrifice fly as the A's won a third straight game following a rare three-game skid.

Minnesota Twins' Jorge Polanco watches his three-run double against the Oakland Athletics during the sixth inning of a baseball game Friday, Sept. 21, 2018, in Oakland, Calif. (AP PhotoBen Margot)

SWINGING A'S

Oakland Athletics' Khris Davis, left, celebrates with Jed Lowrie (8) after hitting a two-run home run off Minnesota Twins' Jose Berrios during the first inning of a baseball game Friday, Sept. 21, 2018, in Oakland, Calif. (AP PhotoBen Margot)

The Twins are 4-17 in Oakland since the start of the 2012 season — Minnesota's most in a city outside the AL Central stops and topping 16 defeats at Yankee Stadium during that stretch. The Twins haven't won a series at the Coliseum since May 18-19, 2011.

Oakland Athletics' Khris Davis, right, celebrates with Jed Lowrie (8) after hitting a two-run home run off Minnesota Twins' Jose Berrios during the first inning of a baseball game Friday, Sept. 21, 2018, in Oakland, Calif. (AP PhotoBen Margot)

TRAINER'S ROOM

He hit a two-run homer in the first, then connected again to end it, lowering the A's magic number of three to clinch a wild card.

Oakland Athletics' Khris Davis, right, celebrates as he passes Minnesota Twins' Ehire Adrianza (16) after hitting a two-run home run off Jose Berrios during the first inning of a baseball game Friday, Sept. 21, 2018, in Oakland, Calif. (AP PhotoBen Margot)

Oakland Athletics' Khris Davis, right, celebrates as he passes Minnesota Twins' Ehire Adrianza (16) after hitting a two-run home run off Jose Berrios during the first inning of a baseball game Friday, Sept. 21, 2018, in Oakland, Calif. (AP PhotoBen Margot)

Pinch-hitter Mark Canha hit a tying two-run homer in the sixth after Minnesota went ahead in the top of the inning.

The Twins lost in walkoff fashion for the 14th time in 2018, 10th via the home run. Minnesota had its four-game winning streak snapped.

Oakland remained 3 1/2 games back of the first-place Astros in the AL West, 1 1/2 games behind the Yankees for the top wild card and 6 1/2 ahead of the Rays for the second wild card.

Minnesota Twins' Tyler Austin, left, Joe Mauer (7) and Ehire Adrianza celebrate after scoring against the Oakland Athletics during the sixth inning of a baseball game Friday, Sept. 21, 2018, in Oakland, Calif. All scored on a double by Jorge Polanco. (AP PhotoBen Margot)

Minnesota Twins' Tyler Austin, left, Joe Mauer (7) and Ehire Adrianza celebrate after scoring against the Oakland Athletics during the sixth inning of a baseball game Friday, Sept. 21, 2018, in Oakland, Calif. All scored on a double by Jorge Polanco. (AP PhotoBen Margot)

Blake Treinen (8-3) pitched the ninth for the A's, coming off a 21-3 win against the Angels and 31 runs the past two games as they rebounded from a rare three-game losing streak.

Canha connected for his second career pinch homer, also done July 14 at San Francisco, and that chased Gabriel Moya.

Jorge Polanco hit a go-ahead, three-run double in Minnesota's six-run sixth and Robbie Grossman had a two-run homer in the inning.

Minnesota Twins' Robbie Grossman, right, celebrates with Max Kepler after hitting a two-run home run off Oakland Athletics' Lou Trivino during the sixth inning of a baseball game Friday, Sept. 21, 2018, in Oakland, Calif. (AP PhotoBen Margot)

Minnesota Twins' Robbie Grossman, right, celebrates with Max Kepler after hitting a two-run home run off Oakland Athletics' Lou Trivino during the sixth inning of a baseball game Friday, Sept. 21, 2018, in Oakland, Calif. (AP PhotoBen Margot)

Jonathan Lucroy added a sacrifice fly as the A's won a third straight game following a rare three-game skid.

Minnesota starter Jose Berrios struck out eight with three walks over 5 2/3 innings, allowing five runs on four hits.

Right-hander Liam Hendriks began as the A's "opener" to throw an inning before Chris Bassitt followed with four innings.

Oakland Athletics' Ramon Laureano scores behind Minnesota Twins catcher Willians Astudillo during the second inning of a baseball game Friday, Sept. 21, 2018, in Oakland, Calif. (AP PhotoBen Margot)

Oakland Athletics' Ramon Laureano scores behind Minnesota Twins catcher Willians Astudillo during the second inning of a baseball game Friday, Sept. 21, 2018, in Oakland, Calif. (AP PhotoBen Margot)

SWINGING A'S

The A's have scored seven or more runs in each of their last eight home games and 76 runs total — the longest in Oakland history and matching the longest in franchise history along with May 30-June 7, 1913, and July 14-20, 1932.

TOUGH VENUE

Minnesota Twins' Jorge Polanco watches his three-run double against the Oakland Athletics during the sixth inning of a baseball game Friday, Sept. 21, 2018, in Oakland, Calif. (AP PhotoBen Margot)

Minnesota Twins' Jorge Polanco watches his three-run double against the Oakland Athletics during the sixth inning of a baseball game Friday, Sept. 21, 2018, in Oakland, Calif. (AP PhotoBen Margot)

The Twins are 4-17 in Oakland since the start of the 2012 season — Minnesota's most in a city outside the AL Central stops and topping 16 defeats at Yankee Stadium during that stretch. The Twins haven't won a series at the Coliseum since May 18-19, 2011.

STATE OF THE A'S

President Dave Kaval told a "State of the A's" gathering that the club will announce a site for a new ballpark, as well as a design for the privately funded venue. General manager David Forst also said it would be a priority to re-sign the club's top players.

Oakland Athletics' Khris Davis, left, celebrates with Jed Lowrie (8) after hitting a two-run home run off Minnesota Twins' Jose Berrios during the first inning of a baseball game Friday, Sept. 21, 2018, in Oakland, Calif. (AP PhotoBen Margot)

Oakland Athletics' Khris Davis, left, celebrates with Jed Lowrie (8) after hitting a two-run home run off Minnesota Twins' Jose Berrios during the first inning of a baseball game Friday, Sept. 21, 2018, in Oakland, Calif. (AP PhotoBen Margot)

TRAINER'S ROOM

Twins: 3B Miguel Sano went from Detroit home to Minneapolis for further tests as he continues to deal with discomfort behind his left knee from a hard slide Sept. 4. ... 2B Logan Forsythe woke up with inflammation in his left knee and it's "not functioning," according to manager Paul Molitor. "The hills of San Francisco is our best guess," Molitor said. ... An MRI on LF Eddie Rosario's right quadriceps muscle showed inflammation. He might return this season, though the Twins will see him Tuesday to determine if there has been progress. ... RHP Addison Reed is away from the team as he and his wife prepare to welcome a baby.

Athletics: RHP Trevor Cahill, scratched from his scheduled start last Saturday at Tampa Bay with a strain in his upper back before getting trigger-point injections, is slated to start Sunday as long as he has no further issues.

Oakland Athletics' Khris Davis, right, celebrates with Jed Lowrie (8) after hitting a two-run home run off Minnesota Twins' Jose Berrios during the first inning of a baseball game Friday, Sept. 21, 2018, in Oakland, Calif. (AP PhotoBen Margot)

Oakland Athletics' Khris Davis, right, celebrates with Jed Lowrie (8) after hitting a two-run home run off Minnesota Twins' Jose Berrios during the first inning of a baseball game Friday, Sept. 21, 2018, in Oakland, Calif. (AP PhotoBen Margot)

UP NEXT

Twins: RHP Chase De Jong (0-1, 3.68 ERA) makes his third start of the season and second of his career vs. the A's seeking his first decision against Oakland.

Athletics: RHP Mike Fiers (12-7, 3.38) will match his career high with his 30th start of the year, also done in 2015 and '16. He is 5-1 with a 3.09 ERA since being traded to the A's by the Tigers on Aug. 6 and won at Minnesota on Aug. 25.

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