Jusuf Nurkic scored 24 points and grabbed 10 rebounds, Damian Lillard had 17 points and the Portland Trail Blazers beat the Philadelphia 76ers 130-115 on Saturday.

The Sixers struggled in their second game without All-Star center Joel Embiid, who is expected to miss at least a week with a sore left knee. Ben Simmons had 29 points and 10 assists and Tobias Harris scored 20.

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Philadelphia 76ers guard Ben Simmons (25) takes a shot during the first half on an NBA basketball game against the Portland Trail Blazers, Saturday, Feb. 23, 2019, in Philadelphia. (AP PhotoLaurence Kesterson)

Jusuf Nurkic scored 24 points and grabbed 10 rebounds, Damian Lillard had 17 points and the Portland Trail Blazers beat the Philadelphia 76ers 130-115 on Saturday.

Philadelphia 76ers guard Jimmy Butler (23) takes a shot over Portland Trail Blazers center Jusuf Nurkic (27) during the first half on an NBA basketball game, Saturday, Feb. 23, 2019, in Philadelphia. (AP PhotoLaurence Kesterson)

Portland opened the second half on a 17-6 run to build a 76-62 lead. Maurice Harkless had consecutive dunks and CJ McCollum also had a dunk in that stretch. Jake Layman's dunk off an alley-oop pass from Lillard extended the lead to 99-80, and the Blazers were up 100-82 going into the fourth.

Philadelphia 76ers guard Jimmy Butler (23) takes a shot over Portland Trail Blazers guard Damian Lillard (0) during the first half on an NBA basketball game, Saturday, Feb. 23, 2019, in Philadelphia. (AP PhotoLaurence Kesterson)

The game was back and forth in the first half until the Blazers outscored Philadelphia 16-7 over the last four minutes of the second quarter to take a 59-56 halftime lead. Nurkic had 10 of the 16.

Portland Trail Blazers forward Maurice Harkless (4) takes a shot over Philadelphia 76ers forward James Ennis III (11) during the first half on an NBA basketball game, Saturday, Feb. 23, 2019, in Philadelphia. (AP PhotoLaurence Kesterson)

76ers: Fell to 24-8 at home. ... Veteran Amir Johnson played four minutes and scored two points, one day after volunteering to play for the Delaware Blue Coats of the G League because he hadn't appeared in a game since Jan. 26. ... JJ Redick shot 1 of 10. ... Jimmy Butler had 15 points.

Philadelphia 76ers guard Ben Simmons (25) takes a shot over Portland Trail Blazers forward Al-Farouq Aminu (8) during the first half on an NBA basketball game, Saturday, Feb. 23, 2019, in Philadelphia. (AP PhotoLaurence Kesterson)

76ers: Visit New Orleans on Monday night.

Without Embiid, the Sixers couldn't keep up in a matchup between the fourth-place teams in each conference. The Blazers (36-23) have won three in a row, including a 22-point victory over Golden State before the All-Star break. Philadelphia (38-22) is 4-4 this month.

Philadelphia 76ers guard Ben Simmons (25) takes a shot during the first half on an NBA basketball game against the Portland Trail Blazers, Saturday, Feb. 23, 2019, in Philadelphia. (AP PhotoLaurence Kesterson)

Philadelphia 76ers guard Ben Simmons (25) takes a shot during the first half on an NBA basketball game against the Portland Trail Blazers, Saturday, Feb. 23, 2019, in Philadelphia. (AP PhotoLaurence Kesterson)

Portland opened the second half on a 17-6 run to build a 76-62 lead. Maurice Harkless had consecutive dunks and CJ McCollum also had a dunk in that stretch. Jake Layman's dunk off an alley-oop pass from Lillard extended the lead to 99-80, and the Blazers were up 100-82 going into the fourth.

The Sixers never challenged in the final quarter, scoring more than two straight points only once after they were already down 21.

Enes Kanter had 16 points and eight rebounds for Portland, which won at Brooklyn on Thursday night.

Philadelphia 76ers guard Jimmy Butler (23) takes a shot over Portland Trail Blazers center Jusuf Nurkic (27) during the first half on an NBA basketball game, Saturday, Feb. 23, 2019, in Philadelphia. (AP PhotoLaurence Kesterson)

Philadelphia 76ers guard Jimmy Butler (23) takes a shot over Portland Trail Blazers center Jusuf Nurkic (27) during the first half on an NBA basketball game, Saturday, Feb. 23, 2019, in Philadelphia. (AP PhotoLaurence Kesterson)

The game was back and forth in the first half until the Blazers outscored Philadelphia 16-7 over the last four minutes of the second quarter to take a 59-56 halftime lead. Nurkic had 10 of the 16.

TIP-INS

Trail Blazers: Improved to 12-15 on the road. ... Kanter played in his second game with his team after being waived by the Knicks. ... G Evan Turner sat out because of left knee soreness. Turner was the No. 2 overall pick by Philadelphia in the 2010 NBA draft. ... Al-Farouq Aminu and McCollum each had 15 points.

Philadelphia 76ers guard Jimmy Butler (23) takes a shot over Portland Trail Blazers guard Damian Lillard (0) during the first half on an NBA basketball game, Saturday, Feb. 23, 2019, in Philadelphia. (AP PhotoLaurence Kesterson)

Philadelphia 76ers guard Jimmy Butler (23) takes a shot over Portland Trail Blazers guard Damian Lillard (0) during the first half on an NBA basketball game, Saturday, Feb. 23, 2019, in Philadelphia. (AP PhotoLaurence Kesterson)

76ers: Fell to 24-8 at home. ... Veteran Amir Johnson played four minutes and scored two points, one day after volunteering to play for the Delaware Blue Coats of the G League because he hadn't appeared in a game since Jan. 26. ... JJ Redick shot 1 of 10. ... Jimmy Butler had 15 points.

UP NEXT

Trail Blazers: Visit Cleveland on Monday night.

Portland Trail Blazers forward Maurice Harkless (4) takes a shot over Philadelphia 76ers forward James Ennis III (11) during the first half on an NBA basketball game, Saturday, Feb. 23, 2019, in Philadelphia. (AP PhotoLaurence Kesterson)

Portland Trail Blazers forward Maurice Harkless (4) takes a shot over Philadelphia 76ers forward James Ennis III (11) during the first half on an NBA basketball game, Saturday, Feb. 23, 2019, in Philadelphia. (AP PhotoLaurence Kesterson)

76ers: Visit New Orleans on Monday night.

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Philadelphia 76ers guard Ben Simmons (25) takes a shot over Portland Trail Blazers forward Al-Farouq Aminu (8) during the first half on an NBA basketball game, Saturday, Feb. 23, 2019, in Philadelphia. (AP PhotoLaurence Kesterson)

Philadelphia 76ers guard Ben Simmons (25) takes a shot over Portland Trail Blazers forward Al-Farouq Aminu (8) during the first half on an NBA basketball game, Saturday, Feb. 23, 2019, in Philadelphia. (AP PhotoLaurence Kesterson)