Jordan Lyles cruised through six innings before taking a line drive off his pitching hand, Starling Marte and Erik González were also pulled following a collision in the field, and the short-handed Pittsburgh Pirates beat the San Francisco Giants 4-1 Friday night.

Lyles (0-2) continued his hot start, striking out six and allowing four hits while dropping his ERA to a major league-best 0.53. He was removed with a bruised right hand after being struck by Joe Panik's line drive in the sixth, through Pittsburgh turned the hot shot into an inning-ending double play.

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Pittsburgh Pirates starting pitcher Jordan Lyles delivers during the first inning of the team's baseball game against the San Francisco Giants in Pittsburgh, Friday, April 19, 2019. (AP PhotoGene J. Puskar)

Jordan Lyles cruised through six innings before taking a line drive off his pitching hand, Starling Marte and Erik González were also pulled following a collision in the field, and the short-handed Pittsburgh Pirates beat the San Francisco Giants 4-1 Friday night.

Pittsburgh Pirates shortstop Erik Gonzalez, left, and center fielder Starling Marte collide going for a ball hit by San Francisco Giants' Yangervis Solarte during the eighth inning of a baseball game Friday, April 19, 2019, in Pittsburgh. (Matt FreedPittsburgh Post-Gazette via AP)

Pittsburgh got all of its runs against Madison Bumarner (1-3) in the first inning. Francisco Cervelli had a two-run double, and Pablo Reyes and JB Shuck added RBI singles. Cervelli ended an 0-for-24 skid.

San Francisco Giants starting pitcher Madison Bumgarner collects himself on the mound during the first inning of the team's baseball game against the Pittsburgh Pirates in Pittsburgh, Friday, April 19, 2019. (AP PhotoGene J. Puskar)

Felipe Vázquez struck out the side in the ninth for his sixth save.

Pittsburgh Pirates' Francisco Cervelli (29) is greeted by manager Clint Hurdle, second from right, after scoring on a single by Pablo Reyes off San Francisco Giants starting pitcher Madison Bumgarner during the first inning of a baseball game in Pittsburgh, Friday, April 19, 2019. (AP PhotoGene J. Puskar)

UP NEXT

Fans sit in the stands at PNC Park in hopes of the tarp coming off the field, during a rain delay before a baseball game between the Pittsburgh Pirates and the San Francisco Giants in Pittsburgh, Friday, April 19, 2019. (AP PhotoGene J. Puskar)

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Pittsburgh Pirates starting pitcher Jordan Lyles delivers during the first inning of a baseball game against the San Francisco Giants in Pittsburgh, Friday, April 19, 2019. (AP PhotoGene J. Puskar)

Pittsburgh Pirates starting pitcher Jordan Lyles delivers during the first inning of a baseball game against the San Francisco Giants in Pittsburgh, Friday, April 19, 2019. (AP PhotoGene J. Puskar)

Marte and González collided in the eighth. Marte charged from center on a softly hit ball by Yangervis Solarte and slammed into the shortstop González. González walked off on his own power. Marte was able to stand briefly, but the team insisted he ride in a cart off the field.

Pittsburgh Pirates starting pitcher Jordan Lyles delivers during the first inning of the team's baseball game against the San Francisco Giants in Pittsburgh, Friday, April 19, 2019. (AP PhotoGene J. Puskar)

Pittsburgh Pirates starting pitcher Jordan Lyles delivers during the first inning of the team's baseball game against the San Francisco Giants in Pittsburgh, Friday, April 19, 2019. (AP PhotoGene J. Puskar)

Pittsburgh got all of its runs against Madison Bumarner (1-3) in the first inning. Francisco Cervelli had a two-run double, and Pablo Reyes and JB Shuck added RBI singles. Cervelli ended an 0-for-24 skid.

Bumgarner allowed just two more hits over his final five innings. He struck out seven.

Buster Posey singled home Solarte in the eighth.

Pittsburgh Pirates shortstop Erik Gonzalez, left, and center fielder Starling Marte collide going for a ball hit by San Francisco Giants' Yangervis Solarte during the eighth inning of a baseball game Friday, April 19, 2019, in Pittsburgh. (Matt FreedPittsburgh Post-Gazette via AP)

Pittsburgh Pirates shortstop Erik Gonzalez, left, and center fielder Starling Marte collide going for a ball hit by San Francisco Giants' Yangervis Solarte during the eighth inning of a baseball game Friday, April 19, 2019, in Pittsburgh. (Matt FreedPittsburgh Post-Gazette via AP)

Felipe Vázquez struck out the side in the ninth for his sixth save.

TRAINER'S ROOM

Pirates: OF Lonnie Chisenhall (broken finger) began his rehab assignment with Triple-A Indianapolis. Manager Clint Hurdle said he's expected to work in left field, right field, first base and possibly at third.

San Francisco Giants starting pitcher Madison Bumgarner collects himself on the mound during the first inning of the team's baseball game against the Pittsburgh Pirates in Pittsburgh, Friday, April 19, 2019. (AP PhotoGene J. Puskar)

San Francisco Giants starting pitcher Madison Bumgarner collects himself on the mound during the first inning of the team's baseball game against the Pittsburgh Pirates in Pittsburgh, Friday, April 19, 2019. (AP PhotoGene J. Puskar)

UP NEXT

Giants: LHP Derek Holland (1-2, 4.09 ERA) is scheduled to start Saturday. He's averaged 11 strikeouts per nine innings through four starts.

Pirates: RHP Jameson Taillon (0-2, 2.43) will make his fifth start of the season. He's 0-1 with a 9.00 ERA in three career starts against San Francisco.

Pittsburgh Pirates' Francisco Cervelli (29) is greeted by manager Clint Hurdle, second from right, after scoring on a single by Pablo Reyes off San Francisco Giants starting pitcher Madison Bumgarner during the first inning of a baseball game in Pittsburgh, Friday, April 19, 2019. (AP PhotoGene J. Puskar)

Pittsburgh Pirates' Francisco Cervelli (29) is greeted by manager Clint Hurdle, second from right, after scoring on a single by Pablo Reyes off San Francisco Giants starting pitcher Madison Bumgarner during the first inning of a baseball game in Pittsburgh, Friday, April 19, 2019. (AP PhotoGene J. Puskar)

More AP MLB: https://apnews.com/MLB and https://twitter.com/AP_Sports

Fans sit in the stands at PNC Park in hopes of the tarp coming off the field, during a rain delay before a baseball game between the Pittsburgh Pirates and the San Francisco Giants in Pittsburgh, Friday, April 19, 2019. (AP PhotoGene J. Puskar)

Fans sit in the stands at PNC Park in hopes of the tarp coming off the field, during a rain delay before a baseball game between the Pittsburgh Pirates and the San Francisco Giants in Pittsburgh, Friday, April 19, 2019. (AP PhotoGene J. Puskar)

Pittsburgh Pirates starting pitcher Jordan Lyles delivers during the first inning of a baseball game against the San Francisco Giants in Pittsburgh, Friday, April 19, 2019. (AP PhotoGene J. Puskar)

Pittsburgh Pirates starting pitcher Jordan Lyles delivers during the first inning of a baseball game against the San Francisco Giants in Pittsburgh, Friday, April 19, 2019. (AP PhotoGene J. Puskar)