Kyle Schwarber hit a solo home run with one out in the bottom of the 10th inning to give the Chicago Cubs a 4-3 comeback victory over the Cincinnati Reds on Tuesday night.

Schwarber stroked a 1-1 pitch from closer Raisel Iglesias (2-8) into the basket in front of the left field bleachers for his 21st homer.

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Chicago Cubs' Kyle Schwarber celebrates with teammates at home plate after hitting a solo home run to defeat the Cincinnati Reds 4-3 in the 10th inning of a baseball game Tuesday, July 16, 2019, in Chicago. (AP PhotoPaul Beaty)

Kyle Schwarber hit a solo home run with one out in the bottom of the 10th inning to give the Chicago Cubs a 4-3 comeback victory over the Cincinnati Reds on Tuesday night.

Chicago Cubs shortstop Javier Baez attempts to apply the tag as Cincinnati Reds' Michael Lorenzen (21) steals second base during the ninth inning of a baseball game Tuesday, July 16, 2019, in Chicago. (AP PhotoPaul Beaty)

Eugenio Suárez homered for Cincinnati, which fell to 7-4 against Chicago this season.

Chicago Cubs manager Joe Maddon left, argues with umpires Sam Holbrook middle, and Sean Barber right, after Anthony Rizzo was called out at second base for interference during the fourth inning of the team's baseball game against the Cincinnati Reds on Tuesday, July 16, 2019, in Chicago. (AP PhotoPaul Beaty)

Cubs spot starter Alec Mills allowed three runs and five hits over six innings in his season debut. He walked one, struck out two and hit four batters with pitches.

Chicago Cubs' Kyle Schwarber celebrates with teammates at home plate after hitting a solo home run to defeat the Cincinnati Reds 4-3 in the 10th inning of a baseball game Tuesday, July 16, 2019, in Chicago. (AP PhotoPaul Beaty)

Suárez opened the scoring with a solo homer in the first on a 3-2 pitch with two outs for a second straight night.

Cincinnati Reds' Eugenio Suarez (7) celebrates with Derek Dietrich (22) after hitting a solo home run during the first inning of the team's baseball game against the Chicago Cubs on Tuesday, July 16, 2019, in Chicago. (AP PhotoPaul Beaty)

Garcia's two-run shot in the second got the Cubs close and Bryant tied it with a solo shot in the sixth to chase DeSclafani, who had retired the previous seven batters.

Cincinnati Reds starter Anthony DeSclafani delivers a pitch during the first inning of the team's baseball game against the Chicago Cubs on Tuesday, July 16, 2019, in Chicago. (AP PhotoPaul Beaty)

GATOR BAIT

Chicago Cubs starter Alec Mills delivers a pitch during the first inning of the team's baseball game against the Cincinnati Reds on Tuesday, July 16, 2019, in Chicago. (AP PhotoPaul Beaty)

Reds: C Curt Casali (right knee soreness) didn't start after being removed from Monday's game. Manager David Bell said Casali is fine and was available in an emergency. . LHP Alex Wood (lower back spasms) threw a bullpen Monday and is scheduled to make a rehab start Wednesday night for Triple-A Louisville.

Robel Garcia and Kris Bryant also connected for the NL Central leaders, who have won six of eight.

Chicago Cubs' Kyle Schwarber celebrates with teammates at home plate after hitting a solo home run to defeat the Cincinnati Reds 4-3 in the 10th inning of a baseball game Tuesday, July 16, 2019, in Chicago. (AP PhotoPaul Beaty)

Chicago Cubs' Kyle Schwarber celebrates with teammates at home plate after hitting a solo home run to defeat the Cincinnati Reds 4-3 in the 10th inning of a baseball game Tuesday, July 16, 2019, in Chicago. (AP PhotoPaul Beaty)

Eugenio Suárez homered for Cincinnati, which fell to 7-4 against Chicago this season.

Steve Cishek (3-5) pitched the 10th and four Cubs relievers combined for four scoreless innings.

New catcher Martín Maldonado, acquired Monday night by Chicago from Kansas City, started and went 0 for 4.

Chicago Cubs shortstop Javier Baez attempts to apply the tag as Cincinnati Reds' Michael Lorenzen (21) steals second base during the ninth inning of a baseball game Tuesday, July 16, 2019, in Chicago. (AP PhotoPaul Beaty)

Chicago Cubs shortstop Javier Baez attempts to apply the tag as Cincinnati Reds' Michael Lorenzen (21) steals second base during the ninth inning of a baseball game Tuesday, July 16, 2019, in Chicago. (AP PhotoPaul Beaty)

Cubs spot starter Alec Mills allowed three runs and five hits over six innings in his season debut. He walked one, struck out two and hit four batters with pitches.

Reds starter Anthony DeSclafani allowed three runs and four hits in 5 2/3 innings.

Cincinnati's Derek Dietrich was hit by a pitch twice to extend his major league-leading total to 20.

Chicago Cubs manager Joe Maddon left, argues with umpires Sam Holbrook middle, and Sean Barber right, after Anthony Rizzo was called out at second base for interference during the fourth inning of the team's baseball game against the Cincinnati Reds on Tuesday, July 16, 2019, in Chicago. (AP PhotoPaul Beaty)

Chicago Cubs manager Joe Maddon left, argues with umpires Sam Holbrook middle, and Sean Barber right, after Anthony Rizzo was called out at second base for interference during the fourth inning of the team's baseball game against the Cincinnati Reds on Tuesday, July 16, 2019, in Chicago. (AP PhotoPaul Beaty)

Suárez opened the scoring with a solo homer in the first on a 3-2 pitch with two outs for a second straight night.

Cincinnati, though, wasn't through. Yasiel Puig and Dietrich were hit by pitches, and Nick Senzel followed with an RBI single. José Peraza then hit a drive into left-center for a double. Dietrich scored easily to make it 3-0, but Senzel was cut down at the plate.

It was Chicago's second stellar defensive play of the inning. Earlier, center fielder Albert Almora Jr. made a sliding, over-the-shoulder catch on the warning track to rob Joey Votto of an extra-base hit.

Chicago Cubs' Kyle Schwarber celebrates with teammates at home plate after hitting a solo home run to defeat the Cincinnati Reds 4-3 in the 10th inning of a baseball game Tuesday, July 16, 2019, in Chicago. (AP PhotoPaul Beaty)

Chicago Cubs' Kyle Schwarber celebrates with teammates at home plate after hitting a solo home run to defeat the Cincinnati Reds 4-3 in the 10th inning of a baseball game Tuesday, July 16, 2019, in Chicago. (AP PhotoPaul Beaty)

Garcia's two-run shot in the second got the Cubs close and Bryant tied it with a solo shot in the sixth to chase DeSclafani, who had retired the previous seven batters.

SUMMER OF '69

The Cubs wore throwback uniforms to honor the 1969 team, which spent much of the season in first place before being overtaken by the Miracle Mets in September. Seven members of the team — including Ferguson Jenkins, Billy Williams and Randy Hundley — attended the game.

Cincinnati Reds' Eugenio Suarez (7) celebrates with Derek Dietrich (22) after hitting a solo home run during the first inning of the team's baseball game against the Chicago Cubs on Tuesday, July 16, 2019, in Chicago. (AP PhotoPaul Beaty)

Cincinnati Reds' Eugenio Suarez (7) celebrates with Derek Dietrich (22) after hitting a solo home run during the first inning of the team's baseball game against the Chicago Cubs on Tuesday, July 16, 2019, in Chicago. (AP PhotoPaul Beaty)

GATOR BAIT

Florida reptile wrangler Frank Robb, who captured the alligator in the lagoon of Chicago's Humboldt Park early Tuesday morning, tossed a ceremonial first pitch and receieved a loud ovation. The 5½-foot alligator, nicknamed Chance the Snapper, did not attend.

TRAINER'S ROOM

Cincinnati Reds starter Anthony DeSclafani delivers a pitch during the first inning of the team's baseball game against the Chicago Cubs on Tuesday, July 16, 2019, in Chicago. (AP PhotoPaul Beaty)

Cincinnati Reds starter Anthony DeSclafani delivers a pitch during the first inning of the team's baseball game against the Chicago Cubs on Tuesday, July 16, 2019, in Chicago. (AP PhotoPaul Beaty)

Reds: C Curt Casali (right knee soreness) didn't start after being removed from Monday's game. Manager David Bell said Casali is fine and was available in an emergency. . LHP Alex Wood (lower back spasms) threw a bullpen Monday and is scheduled to make a rehab start Wednesday night for Triple-A Louisville.

Cubs: C Willson Contreras (right foot strain) said he will rest Wednesday and Thursday before resuming baseball activities on Friday. He is hoping to be activated when he is eligible July 24 at San Francisco.

UP NEXT

Chicago Cubs starter Alec Mills delivers a pitch during the first inning of the team's baseball game against the Cincinnati Reds on Tuesday, July 16, 2019, in Chicago. (AP PhotoPaul Beaty)

Chicago Cubs starter Alec Mills delivers a pitch during the first inning of the team's baseball game against the Cincinnati Reds on Tuesday, July 16, 2019, in Chicago. (AP PhotoPaul Beaty)

Cubs right-hander Yu Darvish (2-4, 4.72 ERA) faces Reds RHP Sonny Gray (5-5, 3.42) in the finale of the three-game series Wednesday afternoon. Darvish, who has 13 no-decisions in 19 starts this season, is still looking for his first win at Wrigley Field since signing with Chicago last year. Gray will be making his first career appearance at the iconic ballpark.

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