Rodrigo Becao scored his first professional goal to help Udinese beat AC Milan 1-0 as new Rossoneri coach Marco Giampaolo's first match in charge ended in defeat on Sunday.
Becao, who was signed by Udinese in the offseason, headed a corner into the bottom right of the net in the 72nd minute.
The 23-year-old defender was signed from Brazilian side Bahia but had spent last season on loan at CSKA Moscow.
Milan had no shots on target but thought it had a penalty after Alessio Romagnoli's header appeared to hit Samir on the arm but, after viewing it several times on the pitchside monitor, the referee deemed it involuntary.
Giampaolo took charge of Milan in June, replacing Gennaro Gattuso.
New Roma coach Paulo Fonseca will take charge of his first match later against Genoa, which also has a new coach in Aurelio Andreazzoli. Also, Atalanta — which finished a surprising third last season — visits Spal.
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