Jose Ruiz walked Tom Murphy with the bases loaded in the ninth inning and the Seattle Mariners won via walk-off for the second straight game, beating the Chicago White Sox 11-10 on Sunday.

A day after former White Sox catcher Omar Narvaez hit a game-ending homer in the 10th, Seattle rallied from five runs down to again beat Chicago.

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Seattle Mariners' Kyle Lewis points to the crowd after driving in Kyle Seager (15) and Austin Nola (23) with a home run against the Chicago White Sox during the sixth inning of a baseball game, Sunday, Sept. 15, 2019, in Seattle. (AP PhotoJohn Froschauer)

Jose Ruiz walked Tom Murphy with the bases loaded in the ninth inning and the Seattle Mariners won via walk-off for the second straight game, beating the Chicago White Sox 11-10 on Sunday.
Chicago White Sox's Welington Castillo points skyward as he reaches home plate after hitting a grand slam off a pitch from Seattle Mariners relief pitcher Brandon Brennan during the fifth inning of a baseball game Sunday, Sept. 15, 2019, in Seattle. (AP PhotoJohn Froschauer)

Austin Adams (2-2) struck out Chicago's top three batters in the ninth for the win. He got Tim Anderson and Yoan Moncada on three pitches each.
Seattle Mariners relief pitcher Brandon Brennan reaches for the ball during the fifth inning against the Chicago White Sox in a baseball game Sunday, Sept. 15, 2019, in Seattle. Brennan gave up a grand slam to Chicago White Sox's Welington Castillo in the inning. (AP PhotoJohn Froschauer)

The walk wiped away an eight-run fifth inning for Chicago that included a grand slam by Wellington Castillo, who had five RBIs, and a three-run home run by Adam Engel.
Chicago White Sox's Welington Castillo celebrates in the dugout after hitting a grand slam on a pitch from Seattle Mariners' Brandon Brennan during a baseball game, Sunday, Sept. 15, 2019, in Seattle. (AP PhotoJohn Froschauer)

Major League Baseball has expressed "regret" over a miscommunication that resulted in Narvaez's game-ending homer.
Seattle Mariners' Austin Nola hits a 2 RBI single against the Chicago White Sox during the fourth inning of a baseball game, Sunday, Sept. 15, 2019, in Seattle. (AP PhotoJohn Froschauer)

TRAINER'S ROOM
Seattle Mariners' Kyle Lewis hits a three-run home run on a pitch from Chicago White Sox relief pitcher Kelvin Herrera during the eighth inning of a baseball game Sunday, Sept. 15, 2019, in Seattle. (AP PhotoJohn Froschauer)

White Sox: RHP Reynaldo Lopez (9-13, 5.35 ERA) will take the mound at Minnesota on Monday.
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Seattle Mariners' Kyle Lewis points to the crowd after driving in Kyle Seager (15) and Austin Nola (23) with a home run against the Chicago White Sox during the sixth inning of a baseball game, Sunday, Sept. 15, 2019, in Seattle. (AP PhotoJohn Froschauer)

Jose Ruiz walked Tom Murphy with the bases loaded in the ninth inning and the Seattle Mariners won via walk-off for the second straight game, beating the Chicago White Sox 11-10 on Sunday.

Chicago White Sox's Welington Castillo points skyward as he reaches home plate after hitting a grand slam off a pitch from Seattle Mariners relief pitcher Brandon Brennan during the fifth inning of a baseball game Sunday, Sept. 15, 2019, in Seattle. (AP PhotoJohn Froschauer)

Austin Adams (2-2) struck out Chicago's top three batters in the ninth for the win. He got Tim Anderson and Yoan Moncada on three pitches each.

Seattle Mariners relief pitcher Brandon Brennan reaches for the ball during the fifth inning against the Chicago White Sox in a baseball game Sunday, Sept. 15, 2019, in Seattle. Brennan gave up a grand slam to Chicago White Sox's Welington Castillo in the inning. (AP PhotoJohn Froschauer)

The walk wiped away an eight-run fifth inning for Chicago that included a grand slam by Wellington Castillo, who had five RBIs, and a three-run home run by Adam Engel.

Chicago White Sox's Welington Castillo celebrates in the dugout after hitting a grand slam on a pitch from Seattle Mariners' Brandon Brennan during a baseball game, Sunday, Sept. 15, 2019, in Seattle. (AP PhotoJohn Froschauer)

Major League Baseball has expressed "regret" over a miscommunication that resulted in Narvaez's game-ending homer.

Seattle Mariners' Austin Nola hits a 2 RBI single against the Chicago White Sox during the fourth inning of a baseball game, Sunday, Sept. 15, 2019, in Seattle. (AP PhotoJohn Froschauer)

TRAINER'S ROOM

Seattle Mariners' Kyle Lewis hits a three-run home run on a pitch from Chicago White Sox relief pitcher Kelvin Herrera during the eighth inning of a baseball game Sunday, Sept. 15, 2019, in Seattle. (AP PhotoJohn Froschauer)

White Sox: RHP Reynaldo Lopez (9-13, 5.35 ERA) will take the mound at Minnesota on Monday.

Top prospect Kyle Lewis hit a three-run homer in the eighth inning, his fourth connection in six major league games. Mallex Smith then tied it at 10 with a single that scored pinch-runner Keon Broxton from second base.

Seattle Mariners' Kyle Lewis points to the crowd after driving in Kyle Seager (15) and Austin Nola (23) with a home run against the Chicago White Sox during the sixth inning of a baseball game, Sunday, Sept. 15, 2019, in Seattle. (AP PhotoJohn Froschauer)

Seattle Mariners' Kyle Lewis points to the crowd after driving in Kyle Seager (15) and Austin Nola (23) with a home run against the Chicago White Sox during the sixth inning of a baseball game, Sunday, Sept. 15, 2019, in Seattle. (AP PhotoJohn Froschauer)

Austin Adams (2-2) struck out Chicago's top three batters in the ninth for the win. He got Tim Anderson and Yoan Moncada on three pitches each.

Ruiz (2-2) gave up a single to Ausitn Nola to open the ninth. Lewis singled and right fielder Ryan Cordell bobbled the ball, allowing Nola to move to third. He was replaced by pinch-runner Braden Bishop. After an intentional walk to load the bases, Ruiz walked Murphy on six pitches.

The Mariners batted around twice, scoring five runs in the fourth and eighth innings.

Chicago White Sox's Welington Castillo points skyward as he reaches home plate after hitting a grand slam off a pitch from Seattle Mariners relief pitcher Brandon Brennan during the fifth inning of a baseball game Sunday, Sept. 15, 2019, in Seattle. (AP PhotoJohn Froschauer)

Chicago White Sox's Welington Castillo points skyward as he reaches home plate after hitting a grand slam off a pitch from Seattle Mariners relief pitcher Brandon Brennan during the fifth inning of a baseball game Sunday, Sept. 15, 2019, in Seattle. (AP PhotoJohn Froschauer)

The walk wiped away an eight-run fifth inning for Chicago that included a grand slam by Wellington Castillo, who had five RBIs, and a three-run home run by Adam Engel.

Nola had four hits.

ABOUT LAST NIGHT

Seattle Mariners relief pitcher Brandon Brennan reaches for the ball during the fifth inning against the Chicago White Sox in a baseball game Sunday, Sept. 15, 2019, in Seattle. Brennan gave up a grand slam to Chicago White Sox's Welington Castillo in the inning. (AP PhotoJohn Froschauer)

Seattle Mariners relief pitcher Brandon Brennan reaches for the ball during the fifth inning against the Chicago White Sox in a baseball game Sunday, Sept. 15, 2019, in Seattle. Brennan gave up a grand slam to Chicago White Sox's Welington Castillo in the inning. (AP PhotoJohn Froschauer)

Major League Baseball has expressed "regret" over a miscommunication that resulted in Narvaez's game-ending homer.

Narvaez hit a ball off the top of the wall in the bottom of the 10th inning that was ruled a home run by umpires. The ball did not clear the fence, and had a replay review been conducted, Narvaez would have been awarded a double and the game would have continued tied at 1. There was confusion over which elements of the play Chicago manager Rick Renteria wanted to challenge. There was also concern that Narvaez may have missed home plate.

"In last night's game there was conversation between the umpires and the White Sox as to the procedure for potentially reviewing two different aspects of the game-ending play," MLB said in a statement Sunday. "There was then a misinterpretation regarding Chicago's desire to have any aspect of the play reviewed. We regret that this miscommunication resulted in not reviewing the home run call on the field."

Chicago White Sox's Welington Castillo celebrates in the dugout after hitting a grand slam on a pitch from Seattle Mariners' Brandon Brennan during a baseball game, Sunday, Sept. 15, 2019, in Seattle. (AP PhotoJohn Froschauer)

Chicago White Sox's Welington Castillo celebrates in the dugout after hitting a grand slam on a pitch from Seattle Mariners' Brandon Brennan during a baseball game, Sunday, Sept. 15, 2019, in Seattle. (AP PhotoJohn Froschauer)

TRAINER'S ROOM

Mariners: OF/DH Domingo Santana (right elbow strain) will be available to the team beginning Tuesday at Pittsburgh. While he'll be on the lineup card, manager Scott Servais said he'd probably be used on a spot basis since it's been several weeks since he's played.

UP NEXT

Seattle Mariners' Austin Nola hits a 2 RBI single against the Chicago White Sox during the fourth inning of a baseball game, Sunday, Sept. 15, 2019, in Seattle. (AP PhotoJohn Froschauer)

Seattle Mariners' Austin Nola hits a 2 RBI single against the Chicago White Sox during the fourth inning of a baseball game, Sunday, Sept. 15, 2019, in Seattle. (AP PhotoJohn Froschauer)

White Sox: RHP Reynaldo Lopez (9-13, 5.35 ERA) will take the mound at Minnesota on Monday.

Mariners: LHP Marco Gonzales (15-11, 4.30 ERA) will seek to extend his career high for victories when Seattle visits Pittsburgh on Tuesday.

More AP MLB: https://apnews.com/MLB and https://twitter.com/AP_Sports

Seattle Mariners' Kyle Lewis hits a three-run home run on a pitch from Chicago White Sox relief pitcher Kelvin Herrera during the eighth inning of a baseball game Sunday, Sept. 15, 2019, in Seattle. (AP PhotoJohn Froschauer)

Seattle Mariners' Kyle Lewis hits a three-run home run on a pitch from Chicago White Sox relief pitcher Kelvin Herrera during the eighth inning of a baseball game Sunday, Sept. 15, 2019, in Seattle. (AP PhotoJohn Froschauer)