Willi Castro hit his first major league homer, one of four connections by the Detroit Tigers in a 6-3 win over the Chicago White Sox on Sunday.

Jeimer Candelario, Gordon Beckham and Victor Reyes also went deep for Detroit, which came into the game having allowed 100 more homers than it had hit.

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Detroit Tigers starter Matthew Boyd pitches against the Chicago White Sox in the first inning of a baseball game, Sunday, Sept. 22, 2019, in Detroit. (AP PhotoJose Juarez)

Willi Castro hit his first major league homer, one of four connections by the Detroit Tigers in a 6-3 win over the Chicago White Sox on Sunday.

Chicago White Sox starter Reynaldo Lopez pitches against the Detroit Tigers in the first inning of a baseball game, Sunday, Sept. 22, 2019, in Detroit. (AP PhotoJose Juarez)

The Tigers (46-109) are trying to avoid the second 110-loss season in club history. They need one win during a three-game home series this week against the Twins to avoid an unfortunate record — they've lost 56 home games, three shy of the record set by the 1939 St. Louis Browns.

Detroit Tigers center fielder Harold Castro scores a run on an RBI single by Christin Stewart during the third inning of a baseball game against the Chicago White Sox, Sunday, Sept. 22, 2019, in Detroit. (AP PhotoJose Juarez)

White Sox starter Reynaldo López (9-15) allowed five runs and nine hits, including three home runs, in four innings.

Detroit Tigers' Dawel Lugo singles against the Chicago White Sox in the third inning of a baseball game, Sunday, Sept. 22, 2019, in Detroit. (AP PhotoJose Juarez)

Candelario tied it in the bottom of the inning, hitting his eighth homer off López, and Beckham made it 3-2 with a solo home run in the second.

Chicago White Sox's Eloy Jimenez hits a double against the Detroit Tigers in the third inning of a baseball game, Sunday, Sept. 22, 2019, in Detroit. (AP PhotoJose Juarez)

The switch-hitting Castro, among Detroit's more promising prospects, is batting .224 through his first 25 career games.

Detroit Tigers' Willi Castro hits a home run against the Chicago White Sox in the seventh inning of a baseball game, Sunday, Sept. 22, 2019, in Detroit. (AP PhotoJose Juarez)

TRAINER'S ROOM

Detroit's Matthew Boyd (9-11), who missed his last start after the death of his grandfather, gave up three runs, eight hits and two walks in five innings.

Detroit Tigers starter Matthew Boyd pitches against the Chicago White Sox in the first inning of a baseball game, Sunday, Sept. 22, 2019, in Detroit. (AP PhotoJose Juarez)

Detroit Tigers starter Matthew Boyd pitches against the Chicago White Sox in the first inning of a baseball game, Sunday, Sept. 22, 2019, in Detroit. (AP PhotoJose Juarez)

The Tigers (46-109) are trying to avoid the second 110-loss season in club history. They need one win during a three-game home series this week against the Twins to avoid an unfortunate record — they've lost 56 home games, three shy of the record set by the 1939 St. Louis Browns.

The White Sox got a homer from Wellington Castillo but lost for the 17th time in 25 games.

Joe Jimenez pitched the ninth for his eighth save.

Chicago White Sox starter Reynaldo Lopez pitches against the Detroit Tigers in the first inning of a baseball game, Sunday, Sept. 22, 2019, in Detroit. (AP PhotoJose Juarez)

Chicago White Sox starter Reynaldo Lopez pitches against the Detroit Tigers in the first inning of a baseball game, Sunday, Sept. 22, 2019, in Detroit. (AP PhotoJose Juarez)

White Sox starter Reynaldo López (9-15) allowed five runs and nine hits, including three home runs, in four innings.

Both teams got two-run homers in the first inning.

Boyd retired the first two batters of the game, but Jose Abreu singled and Eloy Jimenez hit his 30th homer. It was the 242nd homer allowed by the Tigers this season, breaking the franchise record set in 1996.

Detroit Tigers center fielder Harold Castro scores a run on an RBI single by Christin Stewart during the third inning of a baseball game against the Chicago White Sox, Sunday, Sept. 22, 2019, in Detroit. (AP PhotoJose Juarez)

Detroit Tigers center fielder Harold Castro scores a run on an RBI single by Christin Stewart during the third inning of a baseball game against the Chicago White Sox, Sunday, Sept. 22, 2019, in Detroit. (AP PhotoJose Juarez)

Candelario tied it in the bottom of the inning, hitting his eighth homer off López, and Beckham made it 3-2 with a solo home run in the second.

Christin Stewart's RBI single gave the Tigers a 4-2 lead in the third, and Reyes hit a solo homer in the fourth.

Castillo got the White Sox within 5-3 with a two-out RBI single in the fifth, but Castro connected to put the Tigers back up by three in the seventh.

Detroit Tigers' Dawel Lugo singles against the Chicago White Sox in the third inning of a baseball game, Sunday, Sept. 22, 2019, in Detroit. (AP PhotoJose Juarez)

Detroit Tigers' Dawel Lugo singles against the Chicago White Sox in the third inning of a baseball game, Sunday, Sept. 22, 2019, in Detroit. (AP PhotoJose Juarez)

The switch-hitting Castro, among Detroit's more promising prospects, is batting .224 through his first 25 career games.

BOYD GETS CLOSER TO HOMER MARK

Jimenez's first-inning homer was the 39th allowed by Boyd this season. With one start left, he is tied with Jack Morris (1987) for third in team history. Morris allowed 40 homers in 1986, but Denny McLain has the record with 42 in 1966. Morris pitched more than 260 innings in 1986 and 1987, as did McLain in 1966. Boyd will enter his final start with 181 1/3 innings pitched.

Chicago White Sox's Eloy Jimenez hits a double against the Detroit Tigers in the third inning of a baseball game, Sunday, Sept. 22, 2019, in Detroit. (AP PhotoJose Juarez)

Chicago White Sox's Eloy Jimenez hits a double against the Detroit Tigers in the third inning of a baseball game, Sunday, Sept. 22, 2019, in Detroit. (AP PhotoJose Juarez)

TRAINER'S ROOM

Tigers: DH Miguel Cabrera missed a second straight game with knee soreness.

UP NEXT

White Sox: Have Monday off before heading home to start a season-ending, seven-game homestand against the Indians and Tigers. Neither team has announced a starter for Tuesday's opener.

Detroit Tigers' Willi Castro hits a home run against the Chicago White Sox in the seventh inning of a baseball game, Sunday, Sept. 22, 2019, in Detroit. (AP PhotoJose Juarez)

Detroit Tigers' Willi Castro hits a home run against the Chicago White Sox in the seventh inning of a baseball game, Sunday, Sept. 22, 2019, in Detroit. (AP PhotoJose Juarez)

Tigers: Off on Monday before hosting the Twins for three games starting Tuesday. Spencer Turnbull (3-15, 4.66) is scheduled to start for the Tigers against Jake Odorizzi (14-7, 3.59).

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