Germany’s government urged citizens Wednesday to keep their guard up and stick to public health guidelines, as new COVID-19 infections hit a three-month high and schools reopened in the country's most populous state.

Germany's response so far has widely been seen as successful in slowing the spread of the pandemic efficiently and quickly, but the country's disease control authority on Wednesday reported 1,226 new infections. That was the highest number since early May, although the figure has topped 1,000 on several days recently.

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A student gets her face mask prepared by her mother at a school in Gelsenkirchen, Germany, Wednesday, Aug. 12, 2020. Students in North Rhine-Westphalia will have to wear face masks at all times due to the coronavirus pandemic as they return to school this Wednesday. (AP PhotoMartin Meissner)

Germany’s government urged citizens Wednesday to keep their guard up and stick to public health guidelines, as new COVID-19 infections hit a three-month high and schools reopened in the country's most populous state.

Parents wait with children on the schoolyard for the start of their first day at a school in Gelsenkirchen, Germany, Wednesday, Aug. 12, 2020. Students in North Rhine-Westphalia will have to wear face masks at all times due to the coronavirus pandemic as they return to school this Wednesday. (AP PhotoMartin Meissner)

“This is worrying, without doubt,” Spahn told Deutschlandfunk radio. “And it can naturally lead to a new dynamic, if we don’t all now exercise caution.”

Due to the new coronavirus pandemic a man wears a face mask of the German first division soccer team FC Schalke 04 and a hat with the word reading "Deutschland" (Germany) in Gelsenkirchen, Germany, Wednesday, Aug. 12, 2020. (AP PhotoMartin Meissner)

“It’s not about being the first one,” Spahn said. “But it’s about having an effective, tested and therefore secure vaccine.”

Due to the new coronavirus pandemic a man wears a face mask of the German first division soccer team FC Schalke 04 and a hat with the word reading "Deutschland" (Germany) in Gelsenkirchen, Germany, Wednesday, Aug. 12, 2020. (AP PhotoMartin Meissner)

The uptick comes as students are returning to school across the country, adding to concerns.

Passengers wear face masks at a tram in Gelsenkirchen, Germany, Wednesday, Aug. 12, 2020. To avoid the outspread of the coronavirus wearing a mask is mandatory at all public transport. (AP PhotoMartin Meissner)

Some 2.5 million children were returning to school Wednesday in North Rhine-Westphalia, Germany’s most populous state, which has the strictest rules in the country — including that students above elementary school age must wear masks at all times, including in class.

A passenger wears a face mask at a tram in Gelsenkirchen, Germany, Wednesday, Aug. 12, 2020. To avoid the outspread of the coronavirus wearing a mask is mandatory at all public transport. (AP PhotoMartin Meissner)

In Brandenburg, where school resumed Monday, a child and a worker at an after-school program tested positive on Wednesday and authorities were awaiting test results for 68 people who had been in contact with them.

Passengers wear face masks at a tram in Gelsenkirchen, Germany, Wednesday, Aug. 12, 2020. To avoid the outspread of the coronavirus wearing a mask is mandatory at all public transport. (AP PhotoMartin Meissner)

Follow AP pandemic coverage at http://apnews.com/VirusOutbreak and https://apnews.com/UnderstandingtheOutbreak

German Health Minister Jens Spahn arrives for the weekly cabinet meeting at the chancellery in Berlin, Germany, Wednesday, August 12, 2020. (Tobias SchwarzPool Photo via AP)

German Health Minister Jens Spahn arrives for the weekly cabinet meeting at the chancellery in Berlin, Germany, Wednesday, August 12, 2020. (Tobias SchwarzPool Photo via AP)

Health Minister Jens Spahn said smaller and mid-sized outbreaks have occurred in almost all regions, largely driven by travelers returning from abroad and people partying or having family gatherings.

A student gets her face mask prepared by her mother at a school in Gelsenkirchen, Germany, Wednesday, Aug. 12, 2020. Students in North Rhine-Westphalia will have to wear face masks at all times due to the coronavirus pandemic as they return to school this Wednesday. (AP PhotoMartin Meissner)

A student gets her face mask prepared by her mother at a school in Gelsenkirchen, Germany, Wednesday, Aug. 12, 2020. Students in North Rhine-Westphalia will have to wear face masks at all times due to the coronavirus pandemic as they return to school this Wednesday. (AP PhotoMartin Meissner)

“This is worrying, without doubt,” Spahn told Deutschlandfunk radio. “And it can naturally lead to a new dynamic, if we don’t all now exercise caution.”

In the early days of the pandemic the average age of people infected was 50; it is now 34.

Spahn reiterated appeals to wear masks, keep distances and not go overboard in social settings, while expressing skepticism about a new vaccine approved by Russia, the first country worldwide to do so.

Parents wait with children on the schoolyard for the start of their first day at a school in Gelsenkirchen, Germany, Wednesday, Aug. 12, 2020. Students in North Rhine-Westphalia will have to wear face masks at all times due to the coronavirus pandemic as they return to school this Wednesday. (AP PhotoMartin Meissner)

Parents wait with children on the schoolyard for the start of their first day at a school in Gelsenkirchen, Germany, Wednesday, Aug. 12, 2020. Students in North Rhine-Westphalia will have to wear face masks at all times due to the coronavirus pandemic as they return to school this Wednesday. (AP PhotoMartin Meissner)

“It’s not about being the first one,” Spahn said. “But it’s about having an effective, tested and therefore secure vaccine.”

Germany has recorded 218,519 confirmed COVID-19 cases and 9,207 deaths, according to the Robert Koch Institute, the national disease control center. At the height of the pandemic in early April, there were about 6,000 new cases each day.

Many of the current new infections were people who contracted the virus during visits to the western Balkans, Turkey, Bulgaria, Romania, Poland and Spain, the Robert Koch Institute said.

Due to the new coronavirus pandemic a man wears a face mask of the German first division soccer team FC Schalke 04 and a hat with the word reading "Deutschland" (Germany) in Gelsenkirchen, Germany, Wednesday, Aug. 12, 2020. (AP PhotoMartin Meissner)

Due to the new coronavirus pandemic a man wears a face mask of the German first division soccer team FC Schalke 04 and a hat with the word reading "Deutschland" (Germany) in Gelsenkirchen, Germany, Wednesday, Aug. 12, 2020. (AP PhotoMartin Meissner)

The uptick comes as students are returning to school across the country, adding to concerns.

Chancellor Angela Merkel’s spokesman, Steffen Seibert, said restoring economic activity and restarting schools were both critical. He urged Germans not to grow lax about wearing masks or keeping distances, and to practice careful hygiene measures.

“We need to be careful and vigilant,” Seibert said.

Due to the new coronavirus pandemic a man wears a face mask of the German first division soccer team FC Schalke 04 and a hat with the word reading "Deutschland" (Germany) in Gelsenkirchen, Germany, Wednesday, Aug. 12, 2020. (AP PhotoMartin Meissner)

Due to the new coronavirus pandemic a man wears a face mask of the German first division soccer team FC Schalke 04 and a hat with the word reading "Deutschland" (Germany) in Gelsenkirchen, Germany, Wednesday, Aug. 12, 2020. (AP PhotoMartin Meissner)

Some 2.5 million children were returning to school Wednesday in North Rhine-Westphalia, Germany’s most populous state, which has the strictest rules in the country — including that students above elementary school age must wear masks at all times, including in class.

The eastern state of Mecklenburg-Western Pomerania, which has seen the country’s lowest number of coronavirus infections, took a different approach when it became the first state to send children back to school on Aug. 3, with no mask regulations or social distancing rules. It was forced to temporarily close two schools four days later after a student from one and teacher from the other tested positive for COVID-19.

Most of Germany’s 16 states have some sort of a mask rule, usually requiring them in hallways but not in classrooms or schoolyards. Mecklenburg has now implemented such a rule as well, but only for students above primary-school age.

Passengers wear face masks at a tram in Gelsenkirchen, Germany, Wednesday, Aug. 12, 2020. To avoid the outspread of the coronavirus wearing a mask is mandatory at all public transport. (AP PhotoMartin Meissner)

Passengers wear face masks at a tram in Gelsenkirchen, Germany, Wednesday, Aug. 12, 2020. To avoid the outspread of the coronavirus wearing a mask is mandatory at all public transport. (AP PhotoMartin Meissner)

In Brandenburg, where school resumed Monday, a child and a worker at an after-school program tested positive on Wednesday and authorities were awaiting test results for 68 people who had been in contact with them.

And in Schleswig-Holstein in the country's north, where students also went back to class on Monday, a primary school was almost immediately shut down after a teacher tested positive, though it was expected to soon reopen. Two grades at a second school were also sent home on Wednesday as a precaution after a student's sibling tested positive.

David Rising contributed reporting from Berlin.

A passenger wears a face mask at a tram in Gelsenkirchen, Germany, Wednesday, Aug. 12, 2020. To avoid the outspread of the coronavirus wearing a mask is mandatory at all public transport. (AP PhotoMartin Meissner)

A passenger wears a face mask at a tram in Gelsenkirchen, Germany, Wednesday, Aug. 12, 2020. To avoid the outspread of the coronavirus wearing a mask is mandatory at all public transport. (AP PhotoMartin Meissner)

Follow AP pandemic coverage at http://apnews.com/VirusOutbreak and https://apnews.com/UnderstandingtheOutbreak

Passengers wear face masks at a tram in Gelsenkirchen, Germany, Wednesday, Aug. 12, 2020. To avoid the outspread of the coronavirus wearing a mask is mandatory at all public transport. (AP PhotoMartin Meissner)

Passengers wear face masks at a tram in Gelsenkirchen, Germany, Wednesday, Aug. 12, 2020. To avoid the outspread of the coronavirus wearing a mask is mandatory at all public transport. (AP PhotoMartin Meissner)

German Health Minister Jens Spahn arrives for the weekly cabinet meeting at the chancellery in Berlin, Germany, Wednesday, August 12, 2020. (Tobias SchwarzPool Photo via AP)

German Health Minister Jens Spahn arrives for the weekly cabinet meeting at the chancellery in Berlin, Germany, Wednesday, August 12, 2020. (Tobias SchwarzPool Photo via AP)