Lourdes Gurriel homered and Hyun Jin Ryu pitched six solid innings to lead the Toronto Blue Jays to a 2-1 win over the Miami Marlins on Wednesday night.

After Miami’s Sixto Sanchez got through the first four innings on 43 pitches, Gurriel snapped the rookie right-hander’s 11-inning scoreless string with a two-run shot for a 2-0 lead in the fifth. Gurriel drove Sanchez’s 0-1 slider over the left-center wall for his fifth homer.

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Miami Marlins' Brian Anderson, second from right, celebrates a double during the sixth inning of a baseball game against the Toronto Blue Jays, Wednesday, Sept. 2, 2020, in Miami. (AP PhotoWilfredo Lee)

Lourdes Gurriel homered and Hyun Jin Ryu pitched six solid innings to lead the Toronto Blue Jays to a 2-1 win over the Miami Marlins on Wednesday night.

Toronto Blue Jays center fielder Cavan Biggio catches a ball hit by Miami Marlins' Jazz Chisholm during the fifth inning of a baseball game Wednesday, Sept. 2, 2020, in Miami. (AP PhotoWilfredo Lee)

A.J. Cole and Rafael Dolis each pitched scoreless innings and Anthony Bass got his fourth save for the Blue Jays, who are 12-12 in one-run games.

Toronto Blue Jays' Lourdes Gurriel Jr., left, and Rowdy Tellez (44) celebrate after Gurriel hit a home run that scored Tellez during the fifth inning of the team's baseball game against the Miami Marlins, Wednesday, Sept. 2, 2020, in Miami. (AP PhotoWilfredo Lee)

Miami scored its run on Garrett Cooper’s RBI single in the fifth.

Toronto Blue Jays' Jonathan Villar hits a single during the fourth inning of a baseball game against the Miami Marlins, Wednesday, Sept. 2, 2020, in Miami. (AP PhotoWilfredo Lee)

Blue Jays: RHP Trent Thornton underwent surgery Tuesday to remove loose bodies from his pitching elbow. Manager Charlie Montoyo anticipates Thornton will be ready for next spring training.

Toronto Blue Jays' Jonathan Villar is tagged out by Miami Marlins second baseman Jon Berti at second after he attempted to stretch out a single during the first inning of a baseball game, Wednesday, Sept. 2, 2020, in Miami. (AP PhotoWilfredo Lee)

Blue Jays: RHP Taijuan Walker (3-2, 3.27 ERA) will make his second start for Toronto on Thursday at Boston. Acquired from Seattle Aug. 27, Walker pitched six shutout innings against Baltimore in his debut with the Blue Jays on Aug. 29.

Ryu (3-1) allowed one run and six hits, walked two and matched a season high with eight strikeouts.

Miami Marlins' Brian Anderson, second from right, celebrates a double during the sixth inning of a baseball game against the Toronto Blue Jays, Wednesday, Sept. 2, 2020, in Miami. (AP PhotoWilfredo Lee)

Miami Marlins' Brian Anderson, second from right, celebrates a double during the sixth inning of a baseball game against the Toronto Blue Jays, Wednesday, Sept. 2, 2020, in Miami. (AP PhotoWilfredo Lee)

A.J. Cole and Rafael Dolis each pitched scoreless innings and Anthony Bass got his fourth save for the Blue Jays, who are 12-12 in one-run games.

Jonathan Villar had two hits in his second game since joining the Blue Jays in a trade with Miami on Monday.

Sanchez (1-1) was lifted after seven innings. He allowed six hits and struck out five.

Toronto Blue Jays center fielder Cavan Biggio catches a ball hit by Miami Marlins' Jazz Chisholm during the fifth inning of a baseball game Wednesday, Sept. 2, 2020, in Miami. (AP PhotoWilfredo Lee)

Toronto Blue Jays center fielder Cavan Biggio catches a ball hit by Miami Marlins' Jazz Chisholm during the fifth inning of a baseball game Wednesday, Sept. 2, 2020, in Miami. (AP PhotoWilfredo Lee)

Miami scored its run on Garrett Cooper’s RBI single in the fifth.

The Blue Jays committed three baserunning blunders that ended innings. Jonathan Villar was thrown out attempting to stretch a single into a double in the first, and Miami catcher Jorge Alfaro picked off Gurriel at first in the second and Villar at third in the fourth.

TRAINER’S ROOM:

Toronto Blue Jays' Lourdes Gurriel Jr., left, and Rowdy Tellez (44) celebrate after Gurriel hit a home run that scored Tellez during the fifth inning of the team's baseball game against the Miami Marlins, Wednesday, Sept. 2, 2020, in Miami. (AP PhotoWilfredo Lee)

Toronto Blue Jays' Lourdes Gurriel Jr., left, and Rowdy Tellez (44) celebrate after Gurriel hit a home run that scored Tellez during the fifth inning of the team's baseball game against the Miami Marlins, Wednesday, Sept. 2, 2020, in Miami. (AP PhotoWilfredo Lee)

Blue Jays: RHP Trent Thornton underwent surgery Tuesday to remove loose bodies from his pitching elbow. Manager Charlie Montoyo anticipates Thornton will be ready for next spring training.

Marlins: RHP Eliecer Hernandez (lat muscle sprain) was placed on the 10-day injured list. Hernandez felt discomfort and departed after pitching two plus innings in his start Tuesday against the Blue Jays. In a corresponding move, Miami promoted IF Eddy Alvarez from its alternate training site.

UP NEXT:

Toronto Blue Jays' Jonathan Villar hits a single during the fourth inning of a baseball game against the Miami Marlins, Wednesday, Sept. 2, 2020, in Miami. (AP PhotoWilfredo Lee)

Toronto Blue Jays' Jonathan Villar hits a single during the fourth inning of a baseball game against the Miami Marlins, Wednesday, Sept. 2, 2020, in Miami. (AP PhotoWilfredo Lee)

Blue Jays: RHP Taijuan Walker (3-2, 3.27 ERA) will make his second start for Toronto on Thursday at Boston. Acquired from Seattle Aug. 27, Walker pitched six shutout innings against Baltimore in his debut with the Blue Jays on Aug. 29.

Marlins: RHP Pablo Lopez (3-2, 2.10 ERA) will start the opener of a three-game series at Tampa Bay on Friday night. Lopez has not allowed more than two earned runs in any of his six starts this season.

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Toronto Blue Jays' Jonathan Villar is tagged out by Miami Marlins second baseman Jon Berti at second after he attempted to stretch out a single during the first inning of a baseball game, Wednesday, Sept. 2, 2020, in Miami. (AP PhotoWilfredo Lee)

Toronto Blue Jays' Jonathan Villar is tagged out by Miami Marlins second baseman Jon Berti at second after he attempted to stretch out a single during the first inning of a baseball game, Wednesday, Sept. 2, 2020, in Miami. (AP PhotoWilfredo Lee)