A national panel of vaccine experts in Canada recommended Wednesday that provinces extend the interval between the two doses of a COVID-19 shot to quickly inoculate more people, as the prime minister expressed optimism that vaccination timelines could be sped up.

In laying out its new guidelines, the National Advisory Committee on Immunization said extending the dose interval to four months would create opportunities to protect the entire adult population against the virus within a short time frame.

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A vial of the AstraZeneca COVID-19 vaccine doses, one of the first 500,000 of the two million, is displayed that Canada has secured through a deal with the Serum Institute of India in partnership with Verity Pharma, Wednesday, March 3, 2021, at a facility in Milton, Ontario. (Carlos OsorioPool Photo via AP)

A national panel of vaccine experts in Canada recommended Wednesday that provinces extend the interval between the two doses of a COVID-19 shot to quickly inoculate more people, as the prime minister expressed optimism that vaccination timelines could be sped up.

Michael Gray moves a pallet of some of the first 500,000 of the two million AstraZeneca COVID-19 vaccine doses that Canada has secured through a deal with the Serum Institute of India in partnership with Verity Pharma  Wednesday, March 3, 2021, at a facility in Milton, Ontario. (Carlos OsorioPool Photo via AP)

In comparison, the federal government previously said 38% of people would receive two doses by the end of June.

Anita Anand, Canada's Minister of Public Services and Procurement opens a box with some of the first 500,000 of the two million AstraZeneca COVID-19 vaccine doses that Canada has secured through a deal with the Serum Institute of India in partnership with Verity Pharma, Wednesday, March 3, 2021, at a facility in Milton, Ontario. (Carlos OsorioPool Photo via AP)

“Effectiveness against variants of concern will also be monitored closely, and recommendations may need to be revised,” it said, adding there is currently no evidence that a longer interval will affect the emergence of the variants.

Boxes of some of the first 500,000 of the two million AstraZeneca COVID-19 vaccine doses that Canada has secured through a deal with the Serum Institute of India in partnership with Verity Pharma are displayed, Wednesday, March 3, 2021, at a facility in Milton, Ontario. (Carlos OsorioPool Photo via AP)

Manitoba and Quebec also said Wednesday they will delay second doses. Ontario previously said it was weighing a similar move but would seek advice from the federal government.

Anita Anand, Canada's Minister of Public Services and Procurement, poses for a photo with some of the first 500,000 of the two million AstraZeneca COVID-19 vaccine doses that Canada has secured through a deal with the Serum Institute of India in partnership with Verity Pharma, Wednesday, March 3, 2021, at a facility in Milton, Ontario. (Carlos OsorioPool Photo via AP)

Anita Anand, Canada's Minister of Public Services and Procurement, poses for a photo with some of the first 500,000 of the two million AstraZeneca COVID-19 vaccine doses that Canada has secured through a deal with the Serum Institute of India in partnership with Verity Pharma, Wednesday, March 3, 2021, at a facility in Milton, Ontario. (Carlos OsorioPool Photo via AP)

Boxes of some of the first 500,000 of the two million AstraZeneca COVID-19 vaccine doses that Canada has secured through a deal with the Serum Institute of India in partnership with Verity Pharma are displayed, Wednesday, March 3, 2021, at a facility in Milton, Ontario. (Carlos OsorioPool Photo via AP)

Boxes of some of the first 500,000 of the two million AstraZeneca COVID-19 vaccine doses that Canada has secured through a deal with the Serum Institute of India in partnership with Verity Pharma are displayed, Wednesday, March 3, 2021, at a facility in Milton, Ontario. (Carlos OsorioPool Photo via AP)

As many as 80% of Canadians over 16 could receive a single dose by the end of June simply with the expected supply of Pfizer-BioNTech and Moderna vaccines, the panel said. Second doses would begin to be administered in July as more shipments arrive, the panel said, noting that 55 million doses are expected to be delivered in the third quarter of the year.

A vial of the AstraZeneca COVID-19 vaccine doses, one of the first 500,000 of the two million, is displayed that Canada has secured through a deal with the Serum Institute of India in partnership with Verity Pharma, Wednesday, March 3, 2021, at a facility in Milton, Ontario. (Carlos OsorioPool Photo via AP)

A vial of the AstraZeneca COVID-19 vaccine doses, one of the first 500,000 of the two million, is displayed that Canada has secured through a deal with the Serum Institute of India in partnership with Verity Pharma, Wednesday, March 3, 2021, at a facility in Milton, Ontario. (Carlos OsorioPool Photo via AP)

In comparison, the federal government previously said 38% of people would receive two doses by the end of June.

The addition of the newly approved Oxford-AstraZeneca vaccine to the country’s supply could mean almost all Canadians would get their first shot in that time frame, but the federal government has not yet said how many doses of that vaccine will be delivered in the spring and how many in the summer.

“The vaccine effectiveness of the first dose will be monitored closely and the decision to delay the second dose will be continuously assessed based on surveillance and effectiveness data and post-implementation study designs,” the panel wrote.

Michael Gray moves a pallet of some of the first 500,000 of the two million AstraZeneca COVID-19 vaccine doses that Canada has secured through a deal with the Serum Institute of India in partnership with Verity Pharma  Wednesday, March 3, 2021, at a facility in Milton, Ontario. (Carlos OsorioPool Photo via AP)

Michael Gray moves a pallet of some of the first 500,000 of the two million AstraZeneca COVID-19 vaccine doses that Canada has secured through a deal with the Serum Institute of India in partnership with Verity Pharma Wednesday, March 3, 2021, at a facility in Milton, Ontario. (Carlos OsorioPool Photo via AP)

“Effectiveness against variants of concern will also be monitored closely, and recommendations may need to be revised,” it said, adding there is currently no evidence that a longer interval will affect the emergence of the variants.

The updated guidance applies to all COVID-19 vaccines currently approved for use in Canada. Canada's provinces administer health care in the country.

The committee’s recommendation came hours after the Atlantic coast province of Newfoundland and Labrador said it will extend the interval between the first and second doses to four months, and days after health officials in British Columbia announced they were doing so.

Anita Anand, Canada's Minister of Public Services and Procurement opens a box with some of the first 500,000 of the two million AstraZeneca COVID-19 vaccine doses that Canada has secured through a deal with the Serum Institute of India in partnership with Verity Pharma, Wednesday, March 3, 2021, at a facility in Milton, Ontario. (Carlos OsorioPool Photo via AP)

Anita Anand, Canada's Minister of Public Services and Procurement opens a box with some of the first 500,000 of the two million AstraZeneca COVID-19 vaccine doses that Canada has secured through a deal with the Serum Institute of India in partnership with Verity Pharma, Wednesday, March 3, 2021, at a facility in Milton, Ontario. (Carlos OsorioPool Photo via AP)

Manitoba and Quebec also said Wednesday they will delay second doses. Ontario previously said it was weighing a similar move but would seek advice from the federal government.

Earlier Wednesday, Prime Minister Justin Trudeau said any change in public health guidance regarding the timing of the two doses could affect the speed of Canada’s vaccine rollout, as could the approval of more shots.

Canada has had a vaccine shortage until now.

Boxes of some of the first 500,000 of the two million AstraZeneca COVID-19 vaccine doses that Canada has secured through a deal with the Serum Institute of India in partnership with Verity Pharma are displayed, Wednesday, March 3, 2021, at a facility in Milton, Ontario. (Carlos OsorioPool Photo via AP)

Boxes of some of the first 500,000 of the two million AstraZeneca COVID-19 vaccine doses that Canada has secured through a deal with the Serum Institute of India in partnership with Verity Pharma are displayed, Wednesday, March 3, 2021, at a facility in Milton, Ontario. (Carlos OsorioPool Photo via AP)

Anita Anand, Canada's Minister of Public Services and Procurement, poses for a photo with some of the first 500,000 of the two million AstraZeneca COVID-19 vaccine doses that Canada has secured through a deal with the Serum Institute of India in partnership with Verity Pharma, Wednesday, March 3, 2021, at a facility in Milton, Ontario. (Carlos OsorioPool Photo via AP)

Anita Anand, Canada's Minister of Public Services and Procurement, poses for a photo with some of the first 500,000 of the two million AstraZeneca COVID-19 vaccine doses that Canada has secured through a deal with the Serum Institute of India in partnership with Verity Pharma, Wednesday, March 3, 2021, at a facility in Milton, Ontario. (Carlos OsorioPool Photo via AP)

Boxes of some of the first 500,000 of the two million AstraZeneca COVID-19 vaccine doses that Canada has secured through a deal with the Serum Institute of India in partnership with Verity Pharma are displayed, Wednesday, March 3, 2021, at a facility in Milton, Ontario. (Carlos OsorioPool Photo via AP)

Boxes of some of the first 500,000 of the two million AstraZeneca COVID-19 vaccine doses that Canada has secured through a deal with the Serum Institute of India in partnership with Verity Pharma are displayed, Wednesday, March 3, 2021, at a facility in Milton, Ontario. (Carlos OsorioPool Photo via AP)