David Fletcher had a two-run single in the 11th inning. and the Los Angeles Angels beat Toronto 7-5 on Thursday night in the first regular season game played at the Blue Jays' spring training ballpark.

Fletcher's hit to center came on the first pitch from Rafael Dolis, who replaced Ryan Borucki (1-1) with runners on second and third and two outs.

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The Los Angeles Angels and Toronto Blue Jays line up for the anthems prior to a baseball game Thursday, April 8, 2021, in Dunedin, Fla. (AP PhotoMike Carlson)

David Fletcher had a two-run single in the 11th inning. and the Los Angeles Angels beat Toronto 7-5 on Thursday night in the first regular season game played at the Blue Jays' spring training ballpark.

The Los Angeles Angels and Toronto Blue Jays line up for the anthems prior to a baseball game Thursday, April 8, 2021, in Dunedin, Fla. (AP PhotoMike Carlson)

Toronto became the first team in Major League Baseball history to play home openers in three different cities over three consecutive seasons. The Blue Jays played in Toronto in 2019 and moved home games to the ballpark of their Triple-A team in Buffalo, New York, after the Canadian government barred them due to novel coronavirus travel restrictions.

Los Angeles Angels' Mike Trout doubles during the first inning of a baseball game against the Toronto Blue Jays Thursday, April 8, 2021, in Dunedin, Fla. (AP PhotoMike Carlson)

Vladimir Guerrero Jr. and Cavan Biggio homered for the Blue Jays, who won their home opener in Buffalo last season 5-4 in 10 innings over Miami to end a streak of eight consecutive home opening losses. The skid was tied for the third longest in major league history.

Los Angeles Angels' Jose Iglesias (4) congratulates Mike Trout after his solo home run against the Toronto Blue Jays during the fifth inning of a baseball game Thursday, April 8, 2021, in Dunedin, Fla. (AP PhotoMike Carlson)

Trout put the Angels up 4-3 on a long solo drive to left off Ross Stripling in the fifth that went 444 feet. Shohei Ohtani pulled the Angels even at 5-all on a seventh-inning RBI single.

Los Angeles Angels starting pitcher Griffin Canning reacts after giving up a home run to Toronto Blue Jays' Cavan Biggio during the sixth inning of a baseball game Thursday, April 8, 2021, in Dunedin, Fla. (AP PhotoMike Carlson)

Blue Jays: OF George Springer is not expected to make his Toronto debut during the seven-game homestand. He started the season on the injured list with a strained left oblique muscle and now has a low strain right quadriceps strain.

Los Angeles Angels second baseman David Fletcher cannot handle the throw as Toronto Blue Jays' Bo Bichette steals second base during the sixth inning of a baseball game Thursday, April 8, 2021, in Dunedin, Fla. (AP PhotoMike Carlson)

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Toronto Blue Jays starting pitcher Ross Stripling throws against the Los Angeles Angels during the third inning of a baseball game Thursday, April 8, 2021, in Dunedin, Fla. (AP PhotoMike Carlson)

Toronto Blue Jays starting pitcher Ross Stripling throws against the Los Angeles Angels during the third inning of a baseball game Thursday, April 8, 2021, in Dunedin, Fla. (AP PhotoMike Carlson)

Los Angeles Angels starting pitcher Griffin Canning throws against the Toronto Blue Jays during the third inning of a baseball game Thursday, April 8, 2021, in Dunedin, Fla. (AP PhotoMike Carlson)

Los Angeles Angels starting pitcher Griffin Canning throws against the Toronto Blue Jays during the third inning of a baseball game Thursday, April 8, 2021, in Dunedin, Fla. (AP PhotoMike Carlson)

Los Angeles Angels' Mike Trout rounds the bases in front of Toronto Blue Jays shortstop Bo Bichette after his solo home run during the fifth inning of a baseball game Thursday, April 8, 2021, in Dunedin, Fla. (AP PhotoMike Carlson)

Los Angeles Angels' Mike Trout rounds the bases in front of Toronto Blue Jays shortstop Bo Bichette after his solo home run during the fifth inning of a baseball game Thursday, April 8, 2021, in Dunedin, Fla. (AP PhotoMike Carlson)

Junior Guerra (2-0) worked a scoreless 10th before Raisel Iglesias struck out the side for his second save.

The Los Angeles Angels and Toronto Blue Jays line up for the anthems prior to a baseball game Thursday, April 8, 2021, in Dunedin, Fla. (AP PhotoMike Carlson)

The Los Angeles Angels and Toronto Blue Jays line up for the anthems prior to a baseball game Thursday, April 8, 2021, in Dunedin, Fla. (AP PhotoMike Carlson)

Toronto became the first team in Major League Baseball history to play home openers in three different cities over three consecutive seasons. The Blue Jays played in Toronto in 2019 and moved home games to the ballpark of their Triple-A team in Buffalo, New York, after the Canadian government barred them due to novel coronavirus travel restrictions.

TD Ballpark, also the home of Toronto's low Class-A minor league club, last year completed a renovation that cost more than $102 million. Four trucks with additional lighting were brought in for this year’s regular season-games The first three homestands at least will be played in Dunedin, through mid-May.

One reason the Blue Jays opted to stay in Florida was the weather, which was an ideal 80 degrees at first pitch — surprisingly, it was around the same temperature in Buffalo.

The Los Angeles Angels and Toronto Blue Jays line up for the anthems prior to a baseball game Thursday, April 8, 2021, in Dunedin, Fla. (AP PhotoMike Carlson)

The Los Angeles Angels and Toronto Blue Jays line up for the anthems prior to a baseball game Thursday, April 8, 2021, in Dunedin, Fla. (AP PhotoMike Carlson)

Vladimir Guerrero Jr. and Cavan Biggio homered for the Blue Jays, who won their home opener in Buffalo last season 5-4 in 10 innings over Miami to end a streak of eight consecutive home opening losses. The skid was tied for the third longest in major league history.

Los Angeles star Mike Trout went 3 for 5 and had the first regular-season hit at the ballpark, a first-inning double, and also homered. He also had potential go-ahead hit off Julian Merryweather with two on and two outs in the ninth taken away on a diving catch by center fielder Randal Grichuk.

Guerrero connected for a 404-foot, two-run homer to center off Griffin Canning during a three-run first. Biggio’s s solo shot and a run-scoring single by Guerrero in the sixth gave Toronto a 5-4 lead..

Los Angeles Angels' Mike Trout doubles during the first inning of a baseball game against the Toronto Blue Jays Thursday, April 8, 2021, in Dunedin, Fla. (AP PhotoMike Carlson)

Los Angeles Angels' Mike Trout doubles during the first inning of a baseball game against the Toronto Blue Jays Thursday, April 8, 2021, in Dunedin, Fla. (AP PhotoMike Carlson)

Trout put the Angels up 4-3 on a long solo drive to left off Ross Stripling in the fifth that went 444 feet. Shohei Ohtani pulled the Angels even at 5-all on a seventh-inning RBI single.

TRAINER’S ROOM

Angels: RHP Luke Bard has decided to have season-ending right hip surgery. It is scheduled for May 20.

Los Angeles Angels' Jose Iglesias (4) congratulates Mike Trout after his solo home run against the Toronto Blue Jays during the fifth inning of a baseball game Thursday, April 8, 2021, in Dunedin, Fla. (AP PhotoMike Carlson)

Los Angeles Angels' Jose Iglesias (4) congratulates Mike Trout after his solo home run against the Toronto Blue Jays during the fifth inning of a baseball game Thursday, April 8, 2021, in Dunedin, Fla. (AP PhotoMike Carlson)

Blue Jays: OF George Springer is not expected to make his Toronto debut during the seven-game homestand. He started the season on the injured list with a strained left oblique muscle and now has a low strain right quadriceps strain.

UP NEXT

Angels LHP Andrew Heaney (0-1) is scheduled to start Friday night. Toronto has not announced its starter.

Los Angeles Angels starting pitcher Griffin Canning reacts after giving up a home run to Toronto Blue Jays' Cavan Biggio during the sixth inning of a baseball game Thursday, April 8, 2021, in Dunedin, Fla. (AP PhotoMike Carlson)

Los Angeles Angels starting pitcher Griffin Canning reacts after giving up a home run to Toronto Blue Jays' Cavan Biggio during the sixth inning of a baseball game Thursday, April 8, 2021, in Dunedin, Fla. (AP PhotoMike Carlson)

More AP MLB: https://apnews.com/hub/MLB and https://twitter.com/AP_Sports

Los Angeles Angels second baseman David Fletcher cannot handle the throw as Toronto Blue Jays' Bo Bichette steals second base during the sixth inning of a baseball game Thursday, April 8, 2021, in Dunedin, Fla. (AP PhotoMike Carlson)

Los Angeles Angels second baseman David Fletcher cannot handle the throw as Toronto Blue Jays' Bo Bichette steals second base during the sixth inning of a baseball game Thursday, April 8, 2021, in Dunedin, Fla. (AP PhotoMike Carlson)

Toronto Blue Jays starting pitcher Ross Stripling throws against the Los Angeles Angels during the third inning of a baseball game Thursday, April 8, 2021, in Dunedin, Fla. (AP PhotoMike Carlson)

Toronto Blue Jays starting pitcher Ross Stripling throws against the Los Angeles Angels during the third inning of a baseball game Thursday, April 8, 2021, in Dunedin, Fla. (AP PhotoMike Carlson)

Los Angeles Angels starting pitcher Griffin Canning throws against the Toronto Blue Jays during the third inning of a baseball game Thursday, April 8, 2021, in Dunedin, Fla. (AP PhotoMike Carlson)

Los Angeles Angels starting pitcher Griffin Canning throws against the Toronto Blue Jays during the third inning of a baseball game Thursday, April 8, 2021, in Dunedin, Fla. (AP PhotoMike Carlson)

Los Angeles Angels' Mike Trout rounds the bases in front of Toronto Blue Jays shortstop Bo Bichette after his solo home run during the fifth inning of a baseball game Thursday, April 8, 2021, in Dunedin, Fla. (AP PhotoMike Carlson)

Los Angeles Angels' Mike Trout rounds the bases in front of Toronto Blue Jays shortstop Bo Bichette after his solo home run during the fifth inning of a baseball game Thursday, April 8, 2021, in Dunedin, Fla. (AP PhotoMike Carlson)