Israeli troops shot and killed two Palestinians and wounded a third after the men opened fire on a base in the occupied West Bank on Friday, the latest in a series of violent confrontations amid soaring tensions in Jerusalem.

Dozens of Palestinians in an east Jerusalem neighborhood are at risk of being evicted following a long legal battle with Israeli settlers, and Palestinian protesters have clashed with Israeli police in the city on a nightly basis since the start of the Muslim holy month of Ramadan.

The tensions have radiated across the region, with neighboring Jordan warning Israel against further “provocative” steps, and Iran seizing on the sensitivities around Jerusalem and encouraging the violence.

Demonstrators burn representations of Israeli and U.S flags during the annual Al-Quds, or Jerusalem, Day rally in Tehran, Iran, Friday, May 7, 2021. Iran held a limited anti-Israeli rally amid the coronavirus pandemic to mark the Quds Day. After the late Ayatollah Khomeini, leader of the Islamic Revolution and founder of present-day Iran, toppled the pro-Western Shah in 1979, he declared the last Friday of the Muslim holy month of Ramadan as an international day of struggle against Israel and for the liberation of Jerusalem. (AP PhotoVahid Salemi)

Demonstrators burn representations of Israeli and U.S flags during the annual Al-Quds, or Jerusalem, Day rally in Tehran, Iran, Friday, May 7, 2021. Iran held a limited anti-Israeli rally amid the coronavirus pandemic to mark the Quds Day. After the late Ayatollah Khomeini, leader of the Islamic Revolution and founder of present-day Iran, toppled the pro-Western Shah in 1979, he declared the last Friday of the Muslim holy month of Ramadan as an international day of struggle against Israel and for the liberation of Jerusalem. (AP PhotoVahid Salemi)

Israeli police said three attackers fired on the base near the northern West Bank town of Jenin. The Border Police and an Israeli soldier opened fire in response, killing two of the men and wounding a third, who was evacuated to a hospital.

Some 70,000 worshippers attended the final Friday prayers of Ramadan at Al-Aqsa, the Islamic endowment that oversees the site said. Thousands protested afterwards, waving the green flags of the Islamic militant group Hamas and chanting pro-Hamas slogans before dispersing peacefully.

Israelis and Palestinians are bracing more more violence in the coming days.

A demonstrator holds a Palestinian flag during the annual Al-Quds, or Jerusalem, Day rally in Tehran, Iran, Friday, May 7, 2021. Iran held a limited anti-Israeli rally amid the coronavirus pandemic to mark the Quds Day. After the late Ayatollah Khomeini, leader of the Islamic Revolution and founder of present-day Iran, toppled the pro-Western Shah in 1979, he declared the last Friday of the Muslim holy month of Ramadan as an international day of struggle against Israel and for the liberation of Jerusalem. (AP PhotoVahid Salemi)

A demonstrator holds a Palestinian flag during the annual Al-Quds, or Jerusalem, Day rally in Tehran, Iran, Friday, May 7, 2021. Iran held a limited anti-Israeli rally amid the coronavirus pandemic to mark the Quds Day. After the late Ayatollah Khomeini, leader of the Islamic Revolution and founder of present-day Iran, toppled the pro-Western Shah in 1979, he declared the last Friday of the Muslim holy month of Ramadan as an international day of struggle against Israel and for the liberation of Jerusalem. (AP PhotoVahid Salemi)

Sunday night is “Laylat al-Qadr” or the “Night of Destiny,” the most sacred in the Muslim holy month of Ramadan. Worshippers will gather for intense nighttime prayers at the Al-Aqsa mosque compound in Jerusalem's Old City, a flashpoint holy site sacred to Muslims and to Jews, who refer to it as the Temple Mount.

Sunday night is also the start of Jerusalem Day, a national holiday in which Israel celebrates its annexation of east Jerusalem and religious nationalists hold parades and other celebrations in the city. On Monday, an Israeli court is expected to issue a verdict on the evictions.

Israel's archenemy Iran was meanwhile marking its own Quds (Jerusalem) Day on Friday. The national holiday typically features anti-Israel protests and fiery speeches by Iranian leaders predicting Israel's demise.

Demonstrators hold Palestinian flags during the annual Al-Quds, or Jerusalem, Day rally in Tehran, Iran, Friday, May 7, 2021. Iran held a limited anti-Israeli rally amid the coronavirus pandemic to mark the Quds Day. After the late Ayatollah Khomeini, leader of the Islamic Revolution and founder of present-day Iran, toppled the pro-Western Shah in 1979, he declared the last Friday of the Muslim holy month of Ramadan as an international day of struggle against Israel and for the liberation of Jerusalem. (AP PhotoVahid Salemi)

Demonstrators hold Palestinian flags during the annual Al-Quds, or Jerusalem, Day rally in Tehran, Iran, Friday, May 7, 2021. Iran held a limited anti-Israeli rally amid the coronavirus pandemic to mark the Quds Day. After the late Ayatollah Khomeini, leader of the Islamic Revolution and founder of present-day Iran, toppled the pro-Western Shah in 1979, he declared the last Friday of the Muslim holy month of Ramadan as an international day of struggle against Israel and for the liberation of Jerusalem. (AP PhotoVahid Salemi)

“The downward and declining movement of the Zionist regime has begun and will not stop," Supreme Leader Ayatollah Ali Khamenei said in a televised address. He called for continuing armed “resistance” in the Palestinian territories and urged Muslim nations support it.

This year, Ramadan has coincided with an uptick in Israeli-Palestinian violence focused on Jerusalem, where Palestinian protesters have repeatedly clashed with Israeli police over restrictions on outdoor gatherings at the Damascus Gate leading into the Old City.

On Thursday, Israeli forces arrested a Palestinian suspected of carrying out a drive-by shooting earlier this week in the West Bank that killed an Israeli and wounded two others.

On Wednesday, Israeli troops shot and killed a 16-year-old Palestinian during a confrontation near the West Bank city of Nablus. The military said several Palestinians had thrown firebombs toward soldiers.

In recent days, protesters have scuffled with police and settlers over the threatened eviction of dozens of Palestinians in the Sheikh Jarrah neighborhood in east Jerusalem. Several Palestinian families in Sheikh Jarrah have been embroiled in a long-running legal battle with Israeli settler groups trying to acquire property in the neighborhood north of the Old City.

Israel captured east Jerusalem, along with the West Bank and Gaza — territories the Palestinians want for their future state — in the 1967 Mideast war. Israel annexed east Jerusalem in a move not recognized internationally and views the entire city as its capital.

The Palestinians view east Jerusalem — which includes major holy sites for Jews, Christians and Muslims — as their capital, and its fate is one of the most sensitive issues in the conflict.

Neighboring Jordan, which made peace with Israel in 1994 and is the custodian of Al-Aqsa, weighed in on Friday, saying “Israel's continuation of its illegal practices and provocative steps" in the city is a “dangerous game.”

“Building and expanding settlements, confiscating lands, demolishing homes and deporting Palestinians from their homes are illegal practices that perpetuate the occupation and undermine the chances of achieving a just and comprehensive peace, which is a regional and international necessity," Jordan’s Foreign Minister Ayman al-Safadi tweeted.

The Islamic militant group Hamas, which rules the Gaza Strip, has egged on the violence, and Palestinian militants in Gaza have fired rockets in support of the protesters.

Earlier this week, the shadowy commander of Hamas' armed wing, Mohammed Deif, released his first public statement in seven years, in which he warned Israel it would pay a “heavy price” if it evicts Palestinians from their homes.

Associated Press writer Amir Vahdat in Tehran, Iran contributed.