Rafael Devers and Hunter Renfroe homered, Nick Pivetta won his third consecutive start and the Boston Red Sox defeated the Baltimore Orioles 4-3 Sunday.

Boston has won five of six, and at 22-13 owns the best record in baseball. The Orioles fell to a majors-worst 4-13 at home, including 0-6 against the Red Sox.

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Boston Red Sox's Rafael Devers, right, celebrates his home run with Hunter Renfroe, left, during the second inning of a baseball game against the Baltimore Orioles, Sunday, May 9, 2021, in Baltimore. (AP PhotoNick Wass)

Rafael Devers and Hunter Renfroe homered, Nick Pivetta won his third consecutive start and the Boston Red Sox defeated the Baltimore Orioles 4-3 Sunday.

Boston Red Sox's Marwin Gonzalez, front left, is tagged out by Baltimore Orioles first baseman Ryan Mountcastle, right, on a pickoff during the third inning of a baseball game, Sunday, May 9, 2021, in Baltimore. (AP PhotoNick Wass)

Renfroe added a solo shot off Cole Sulser in the eighth.

Baltimore Orioles' right fielder Ryan McKenna cannot get to a ball hit by Boston Red Sox's Kevin Plawecki during the seventh inning of a baseball game, Sunday, May 9, 2021, in Baltimore. McKenna was charged with a fielding error on the play and Plawecki reached first base. (AP PhotoNick Wass)

Pivetta ran into his only serious trouble right away. After retiring his first two batters of the day, he issued consecutive walks and then gave up Ryan Mountcastle’s RBI single.

Boston Red Sox's Rafael Devers gestures as he stands on second base after he hit a two-RBI double during the sixth inning of a baseball game against the Baltimore Orioles, Sunday, May 9, 2021, in Baltimore. (AP PhotoNick Wass)

Baltimore shortstop Freddy Galvis extended his hitting streak to 10 with a single in the fourth.

Baltimore Orioles starting pitcher Dean Kremer delivers a pitch during the first inning of a baseball game against the Boston Red Sox, Sunday, May 9, 2021, in Baltimore. (AP PhotoNick Wass)

Orioles: Baltimore placed RHP Dillon Tate (left hamstring strain) on the 10-day IL, retroactive to Friday. Tate is 0-1 with a 3.46 ERA in 11 games this season. The Orioles recalled OF Ryan McKenna from Triple-A Norfolk.

Boston Red Sox starting pitcher Nick Pivetta delivers a pitch during the first inning of a baseball game against the Baltimore Orioles, Sunday, May 9, 2021, in Baltimore. (AP PhotoNick Wass)

Orioles: RHP Jorge López (1-3, 6.49), who allowed seven runs in four innings against Boston on April 11, takes the mound as the four-game series concludes.

Boston Red Sox right fielder Hunter Renfroe makes a catch on a line drive by Baltimore Orioles' Cedric Mullins, not seen, for the out during the first inning of a baseball game, Sunday, May 9, 2021, in Baltimore. (AP PhotoNick Wass)

Boston Red Sox right fielder Hunter Renfroe makes a catch on a line drive by Baltimore Orioles' Cedric Mullins, not seen, for the out during the first inning of a baseball game, Sunday, May 9, 2021, in Baltimore. (AP PhotoNick Wass)

Devers, who homered off Baltimore starter Dean Kremer in the second inning, hit a two-run double off reliever Adam Plutko in the sixth to give Boston a 3-2 lead.

Boston Red Sox's Rafael Devers, right, celebrates his home run with Hunter Renfroe, left, during the second inning of a baseball game against the Baltimore Orioles, Sunday, May 9, 2021, in Baltimore. (AP PhotoNick Wass)

Boston Red Sox's Rafael Devers, right, celebrates his home run with Hunter Renfroe, left, during the second inning of a baseball game against the Baltimore Orioles, Sunday, May 9, 2021, in Baltimore. (AP PhotoNick Wass)

Renfroe added a solo shot off Cole Sulser in the eighth.

Pivetta (5-0) allowed two runs and three hits in six innings to improve to 7-0 since being traded from Philadelphia to Boston last August. He is only the fourth starting pitcher in franchise history to win at least his first seven decisions with the team, joining George Winter (7-0 in 1901), Dave Ferriss (8-0 in 1945) and John Burkett (7-0 in 2002).

Matt Barnes earned his eighth save in as many tries with a perfect ninth.

Boston Red Sox's Marwin Gonzalez, front left, is tagged out by Baltimore Orioles first baseman Ryan Mountcastle, right, on a pickoff during the third inning of a baseball game, Sunday, May 9, 2021, in Baltimore. (AP PhotoNick Wass)

Boston Red Sox's Marwin Gonzalez, front left, is tagged out by Baltimore Orioles first baseman Ryan Mountcastle, right, on a pickoff during the third inning of a baseball game, Sunday, May 9, 2021, in Baltimore. (AP PhotoNick Wass)

Pivetta ran into his only serious trouble right away. After retiring his first two batters of the day, he issued consecutive walks and then gave up Ryan Mountcastle’s RBI single.

Baltimore’s Cedric Mullins belted a two-out solo homer in the fifth.

Kremer (0-3) surrendered three runs and five hits in five-plus innings and has not won in nine starts since beating the New York Yankees in his major league debut on Sept. 6.

Baltimore Orioles' right fielder Ryan McKenna cannot get to a ball hit by Boston Red Sox's Kevin Plawecki during the seventh inning of a baseball game, Sunday, May 9, 2021, in Baltimore. McKenna was charged with a fielding error on the play and Plawecki reached first base. (AP PhotoNick Wass)

Baltimore Orioles' right fielder Ryan McKenna cannot get to a ball hit by Boston Red Sox's Kevin Plawecki during the seventh inning of a baseball game, Sunday, May 9, 2021, in Baltimore. McKenna was charged with a fielding error on the play and Plawecki reached first base. (AP PhotoNick Wass)

Baltimore shortstop Freddy Galvis extended his hitting streak to 10 with a single in the fourth.

TRAINER’S ROOM

Red Sox: Boston placed INF Christian Arroyo (left hand contusion) on the 10-day injured list, retroactive to Friday, and recalled INF Jonathan Araúz from Triple-A Worcester. Arroyo was hit on the hand with a pitch Wednesday. … Boston has shut down RHP Tanner Houck after he was diagnosed with a sore flexor muscle at Worcester. “There’s no timetable, but this is something we feel will be short term,” manager Alex Cora said. “It’s not something where we are overly concerned.” Houck was 0-2 with a 4.35 ERA in three April appearances with the Red Sox.

Boston Red Sox's Rafael Devers gestures as he stands on second base after he hit a two-RBI double during the sixth inning of a baseball game against the Baltimore Orioles, Sunday, May 9, 2021, in Baltimore. (AP PhotoNick Wass)

Boston Red Sox's Rafael Devers gestures as he stands on second base after he hit a two-RBI double during the sixth inning of a baseball game against the Baltimore Orioles, Sunday, May 9, 2021, in Baltimore. (AP PhotoNick Wass)

Orioles: Baltimore placed RHP Dillon Tate (left hamstring strain) on the 10-day IL, retroactive to Friday. Tate is 0-1 with a 3.46 ERA in 11 games this season. The Orioles recalled OF Ryan McKenna from Triple-A Norfolk.

UP NEXT

Red Sox: LHP Martín Pérez (0-2, 4.40 ERA), who has a 2.53 ERA in two road starts this season, gets the ball for Boston.

Baltimore Orioles starting pitcher Dean Kremer delivers a pitch during the first inning of a baseball game against the Boston Red Sox, Sunday, May 9, 2021, in Baltimore. (AP PhotoNick Wass)

Baltimore Orioles starting pitcher Dean Kremer delivers a pitch during the first inning of a baseball game against the Boston Red Sox, Sunday, May 9, 2021, in Baltimore. (AP PhotoNick Wass)

Orioles: RHP Jorge López (1-3, 6.49), who allowed seven runs in four innings against Boston on April 11, takes the mound as the four-game series concludes.

More AP MLB: https://apnews.com/MLB and https://twitter.com/AP_Sports

Boston Red Sox starting pitcher Nick Pivetta delivers a pitch during the first inning of a baseball game against the Baltimore Orioles, Sunday, May 9, 2021, in Baltimore. (AP PhotoNick Wass)

Boston Red Sox starting pitcher Nick Pivetta delivers a pitch during the first inning of a baseball game against the Baltimore Orioles, Sunday, May 9, 2021, in Baltimore. (AP PhotoNick Wass)

Boston Red Sox right fielder Hunter Renfroe makes a catch on a line drive by Baltimore Orioles' Cedric Mullins, not seen, for the out during the first inning of a baseball game, Sunday, May 9, 2021, in Baltimore. (AP PhotoNick Wass)

Boston Red Sox right fielder Hunter Renfroe makes a catch on a line drive by Baltimore Orioles' Cedric Mullins, not seen, for the out during the first inning of a baseball game, Sunday, May 9, 2021, in Baltimore. (AP PhotoNick Wass)