The Latest on confrontations between Israelis and Palestinians (all times local):

1:36 p.m.

An Israeli airstrike has hit another high-rise building in the middle of Gaza City.

Local media reported that Tuesday's airstrike killed an unknown number of militants inside.

But the airstrike in the middle class Rimal neighborhood sent terrified residents of the building into the streets. They included screaming women and children, some of whom were barefoot.

Earlier Tuesday, Israel hit a high-rise where it said a Hamas commander was hiding. Palestinian health officials said a woman and her 19-year-old disabled son were killed. The fate of the Hamas commander was not immediately known.

Since Monday, Gaza militants have also fired hundreds of rockets toward Israel.

The escalation in the conflict was sparked by weeks of tensions in contested Jerusalem.