Bryce Harper treated heckling fans to a long home run, Andrew Knapp delivered a key pinch-hit in place of injured catcher J.T. Realmuto and the Philadelphia Phillies beat the Washington Nationals 6-2 on Tuesday night.

Realmuto was hit in the left knee by Josh Bell's foul ball in the seventh inning. The star catcher stayed in the game until Bell struck out to end the inning.

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Philadelphia Phillies' Bryce Harper watches his solo home run during the first inning of a baseball game against the Washington Nationals at Nationals Park, Tuesday, May 11, 2021, in Washington. (AP PhotoAlex Brandon)

Bryce Harper treated heckling fans to a long home run, Andrew Knapp delivered a key pinch-hit in place of injured catcher J.T. Realmuto and the Philadelphia Phillies beat the Washington Nationals 6-2 on Tuesday night.

Philadelphia Phillies starting pitcher Chase Anderson throws during the first inning of a baseball game against the Washington Nationals at Nationals Park, Tuesday, May 11, 2021, in Washington. (AP PhotoAlex Brandon)

Harper, the 2015 MVP who played for Washington from 2012-18, signed a 13-year, $330 million with Philadelphia two years ago. He was regularly booed when the Phillies visited Nationals Park in 2019, then received a reprieve last year when fans weren’t permitted to attend games during the truncated season in the midst of the pandemic.

Washington Nationals starting pitcher Erick Fedde throws during the third inning of a baseball game against the Philadelphia Phillies at Nationals Park, Tuesday, May 11, 2021, in Washington. (AP PhotoAlex Brandon)

Chase Anderson (2-3) retired 15 of 16 after yielding two hits to begin the game, then Turner hit his eighth homer on the first pitch of the sixth.

Philadelphia Phillies' Bryce Harper hits a solo home run during the first inning of a baseball game against the Washington Nationals at Nationals Park, Tuesday, May 11, 2021, in Washington. (AP PhotoAlex Brandon)

Rhys Hoskins delivered the Phillies second run with an RBI single in the third, and Andrew McCutchen hit a sacrifice fly an inning later.

Washington Nationals shortstop Trea Turner can't handle a hit by Philadelphia Phillies' Didi Gregorius during the sixth inning of a baseball game at Nationals Park, Tuesday, May 11, 2021, in Washington. (AP PhotoAlex Brandon)

Nationals: RHP Stephen Strasburg (shoulder inflammation) threw 62 pitches in a simulated game Tuesday. “He threw a little bit more than we anticipated, which to me is a good sign,” manager Dave Martinez said. … RHP Wander Suero (left oblique strain) was examined and worked out before Tuesday’s game. Martinez said if things went well the reliever could be activated Wednesday or Thursday.

Washington Nationals' Kyle Schwarber is hit by a pitch during the fourth inning of a baseball game against the Philadelphia Phillies at Nationals Park, Tuesday, May 11, 2021, in Washington. (AP PhotoAlex Brandon)

Nationals: LHP Jon Lester (0-1, 2.70 ERA), who has gone five innings in both of his starts this year for Washington, takes the mound as the series continues.

Trea Turner homered for Washington, which has dropped six of seven since reaching .500 and briefly taking the NL East lead on May 2. It was the first of 19 games between the teams this season, all crammed between May 11 and Sept. 1.

Philadelphia Phillies' Bryce Harper watches his solo home run during the first inning of a baseball game against the Washington Nationals at Nationals Park, Tuesday, May 11, 2021, in Washington. (AP PhotoAlex Brandon)

Philadelphia Phillies' Bryce Harper watches his solo home run during the first inning of a baseball game against the Washington Nationals at Nationals Park, Tuesday, May 11, 2021, in Washington. (AP PhotoAlex Brandon)

Harper, the 2015 MVP who played for Washington from 2012-18, signed a 13-year, $330 million with Philadelphia two years ago. He was regularly booed when the Phillies visited Nationals Park in 2019, then received a reprieve last year when fans weren’t permitted to attend games during the truncated season in the midst of the pandemic.

It was back to normal as Philadelphia played its first game in Washington this year. Harper was jeered when he stepped into the box in the first inning --- and two pitches later blasted an offering from Erick Fedde off the front of the second deck in right field.

While Harper began things, Knapp effectively finished off the victory for Philadelphia. Knapp capped a three-run inning with a two-run, bases-loaded single.

Philadelphia Phillies starting pitcher Chase Anderson throws during the first inning of a baseball game against the Washington Nationals at Nationals Park, Tuesday, May 11, 2021, in Washington. (AP PhotoAlex Brandon)

Philadelphia Phillies starting pitcher Chase Anderson throws during the first inning of a baseball game against the Washington Nationals at Nationals Park, Tuesday, May 11, 2021, in Washington. (AP PhotoAlex Brandon)

Chase Anderson (2-3) retired 15 of 16 after yielding two hits to begin the game, then Turner hit his eighth homer on the first pitch of the sixth.

Juan Soto walked to end Anderson’s night and scored two batters later on Kyle Schwarber’s single.

Fedde (2-4) threw only one perfect inning --- his last --- while making it through five. He surrendered five hits, three walks and three runs and struck out five.

Washington Nationals starting pitcher Erick Fedde throws during the third inning of a baseball game against the Philadelphia Phillies at Nationals Park, Tuesday, May 11, 2021, in Washington. (AP PhotoAlex Brandon)

Washington Nationals starting pitcher Erick Fedde throws during the third inning of a baseball game against the Philadelphia Phillies at Nationals Park, Tuesday, May 11, 2021, in Washington. (AP PhotoAlex Brandon)

Rhys Hoskins delivered the Phillies second run with an RBI single in the third, and Andrew McCutchen hit a sacrifice fly an inning later.

TRAINER’S ROOM

Phillies: LHP Archie Bradley (left oblique strain) is scheduled to make a rehabilitation appearance Wednesday for Triple-A Lehigh Valley. Bradley has not pitched for Philadelphia since April 10.

Philadelphia Phillies' Bryce Harper hits a solo home run during the first inning of a baseball game against the Washington Nationals at Nationals Park, Tuesday, May 11, 2021, in Washington. (AP PhotoAlex Brandon)

Philadelphia Phillies' Bryce Harper hits a solo home run during the first inning of a baseball game against the Washington Nationals at Nationals Park, Tuesday, May 11, 2021, in Washington. (AP PhotoAlex Brandon)

Nationals: RHP Stephen Strasburg (shoulder inflammation) threw 62 pitches in a simulated game Tuesday. “He threw a little bit more than we anticipated, which to me is a good sign,” manager Dave Martinez said. … RHP Wander Suero (left oblique strain) was examined and worked out before Tuesday’s game. Martinez said if things went well the reliever could be activated Wednesday or Thursday.

UP NEXT

Phillies: RHP Zack Wheeler (3-2, 2.83 ERA) makes his start since his three-hit shutout of Milwaukee on Thursday. He was 1-1 with a 1.46 ERA in two starts against Washington last season.

Washington Nationals shortstop Trea Turner can't handle a hit by Philadelphia Phillies' Didi Gregorius during the sixth inning of a baseball game at Nationals Park, Tuesday, May 11, 2021, in Washington. (AP PhotoAlex Brandon)

Washington Nationals shortstop Trea Turner can't handle a hit by Philadelphia Phillies' Didi Gregorius during the sixth inning of a baseball game at Nationals Park, Tuesday, May 11, 2021, in Washington. (AP PhotoAlex Brandon)

Nationals: LHP Jon Lester (0-1, 2.70 ERA), who has gone five innings in both of his starts this year for Washington, takes the mound as the series continues.

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Washington Nationals' Kyle Schwarber is hit by a pitch during the fourth inning of a baseball game against the Philadelphia Phillies at Nationals Park, Tuesday, May 11, 2021, in Washington. (AP PhotoAlex Brandon)

Washington Nationals' Kyle Schwarber is hit by a pitch during the fourth inning of a baseball game against the Philadelphia Phillies at Nationals Park, Tuesday, May 11, 2021, in Washington. (AP PhotoAlex Brandon)