James Kaprielian got the victory in his first major league start with five innings of one-run ball, Matt Olson homered and the Oakland Athletics held off the Boston Red Sox 4-1 Wednesday night.

Sean Murphy and Jed Lowrie also had RBIs for the A’s, who will try for a three-game sweep Thursday.

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Oakland Athletics' Matt Olson, right, rounds the bases on his solo home run off Boston Red Sox starting pitcher Eduardo Rodriguez during the sixth inning of a baseball game, Wednesday, May 12, 2021, in Boston. (AP PhotoCharles Krupa)

James Kaprielian got the victory in his first major league start with five innings of one-run ball, Matt Olson homered and the Oakland Athletics held off the Boston Red Sox 4-1 Wednesday night.

Boston Red Sox starting pitcher Eduardo Rodriguez looks down at a fresh baseball after giving up a solo home run to Oakland Athletics' Matt Olson during the sixth inning of a baseball game, Wednesday, May 12, 2021, in Boston. (AP PhotoCharles Krupa)

Boston has lost three straight.

Boston Red Sox's Marwin Gonzalez, left, is tagged out by Oakland Athletics third baseman Matt Chapman after getting caught in a run down during the fifth inning of a baseball game, Wednesday, May 12, 2021, in Boston. (AP PhotoCharles Krupa)

Oakland pounded out seven hits and four runs against Boston starter Eduardo Rodriguez (5-1). He struck out nine but also balked in a run and didn’t get the run support he received in his previous six starts.

Oakland Athletics' Ramon Laureano argues with home plate umpire Ryan Wills after striking out in the third inning of a baseball game against the Boston Red Sox, Wednesday, May 12, 2021, in Boston. (AP PhotoCharles Krupa)

With the score tied 1-1, Mitch Moreland led off the fifth with a single, followed by Elvis Andrus' double. Rodriguez struck out Mark Canha, but Lowrie’s groundout to Xander Bogaerts was deep enough to score Moreland and move Andrus to third.

Boston Red Sox starting pitcher Eduardo Rodriguez delivers during the first inning of a baseball game against the Oakland Athletics, Wednesday, May 12, 2021, in Boston. (AP PhotoCharles Krupa)

Athletics: Reinstated C Aramis Garcia from the injured list. He was on the opening day roster and hit .135 with a home run and two RBIs in 13 games before being placed on the 10-day IL May 4 with viral enteritis.

Oakland Athletics right fielder Stephen Piscotty dives but can't make the play on a double by Boston Red Sox's Marwin Gonzalez during the first inning of a baseball game, Wednesday, May 12, 2021, in Boston. (AP PhotoCharles Krupa)

Oakland center fielder Ramón Laureano was called out on strikes to end the A’s half of the third inning. He remained at the plate arguing as Boston’s players exited. He eventually threw both his batting helmet and bat and was ejected by home plate umpire Ryan Wills.

Oakland Athletics starting pitcher James Kaprielian delivers during the first inning of a baseball game against the Boston Red Sox, Wednesday, May 12, 2021, in Boston. (AP PhotoCharles Krupa)

Athletics: LHP Sean Manaea (3-1, 3.07 ERA) will make his eighth start of the season. He is 3-0 with a 2.23 ERA over his last six starts.

Oakland Athletics starting pitcher James Kaprielian delivers during the first inning of a baseball game against the Boston Red Sox, Wednesday, May 12, 2021, in Boston. (AP PhotoCharles Krupa)

Oakland Athletics starting pitcher James Kaprielian delivers during the first inning of a baseball game against the Boston Red Sox, Wednesday, May 12, 2021, in Boston. (AP PhotoCharles Krupa)

Burch Smith and Lou Trivino combined to pitch three scoreless innings for Oakland, and Jake Diekman completed a scoreless ninth for his fifth save.

Oakland Athletics' Matt Olson, right, rounds the bases on his solo home run off Boston Red Sox starting pitcher Eduardo Rodriguez during the sixth inning of a baseball game, Wednesday, May 12, 2021, in Boston. (AP PhotoCharles Krupa)

Oakland Athletics' Matt Olson, right, rounds the bases on his solo home run off Boston Red Sox starting pitcher Eduardo Rodriguez during the sixth inning of a baseball game, Wednesday, May 12, 2021, in Boston. (AP PhotoCharles Krupa)

Boston has lost three straight.

Kaprielian (1-0) settled down after a rocky first inning and ended his night after giving up just four hits and three walks with six strikeouts.

The right-hander made his first start of the season at Triple-A Las Vegas last week but got the call after starters Jesus Luzardo and Mike Fiers both went on the injured list. He made two big league relief appearances last season.

Boston Red Sox starting pitcher Eduardo Rodriguez looks down at a fresh baseball after giving up a solo home run to Oakland Athletics' Matt Olson during the sixth inning of a baseball game, Wednesday, May 12, 2021, in Boston. (AP PhotoCharles Krupa)

Boston Red Sox starting pitcher Eduardo Rodriguez looks down at a fresh baseball after giving up a solo home run to Oakland Athletics' Matt Olson during the sixth inning of a baseball game, Wednesday, May 12, 2021, in Boston. (AP PhotoCharles Krupa)

Oakland pounded out seven hits and four runs against Boston starter Eduardo Rodriguez (5-1). He struck out nine but also balked in a run and didn’t get the run support he received in his previous six starts.

Boston entered the night leading the major leagues in runs (190), but it struggled with runners on base. The Red Sox loaded the bases with no outs in the first inning, had runners on the corners with no outs in the fifth, and runners at second and third with one out in the eighth.

Meanwhile, the A’s did just enough with their handful of opportunities.

Boston Red Sox's Marwin Gonzalez, left, is tagged out by Oakland Athletics third baseman Matt Chapman after getting caught in a run down during the fifth inning of a baseball game, Wednesday, May 12, 2021, in Boston. (AP PhotoCharles Krupa)

Boston Red Sox's Marwin Gonzalez, left, is tagged out by Oakland Athletics third baseman Matt Chapman after getting caught in a run down during the fifth inning of a baseball game, Wednesday, May 12, 2021, in Boston. (AP PhotoCharles Krupa)

With the score tied 1-1, Mitch Moreland led off the fifth with a single, followed by Elvis Andrus' double. Rodriguez struck out Mark Canha, but Lowrie’s groundout to Xander Bogaerts was deep enough to score Moreland and move Andrus to third.

The lead grew to 3-1 when Rodriguez was called for a balk, scoring Andrus.

TRAINER’S ROOM

Oakland Athletics' Ramon Laureano argues with home plate umpire Ryan Wills after striking out in the third inning of a baseball game against the Boston Red Sox, Wednesday, May 12, 2021, in Boston. (AP PhotoCharles Krupa)

Oakland Athletics' Ramon Laureano argues with home plate umpire Ryan Wills after striking out in the third inning of a baseball game against the Boston Red Sox, Wednesday, May 12, 2021, in Boston. (AP PhotoCharles Krupa)

Athletics: Reinstated C Aramis Garcia from the injured list. He was on the opening day roster and hit .135 with a home run and two RBIs in 13 games before being placed on the 10-day IL May 4 with viral enteritis.

Red Sox: Placed right-handed pitcher Nick Pivetta on the COVID-19 injured list after he experienced side effects from his recent vaccination. Eduard Bazardo was recalled from Triple-A Worcester to take his roster spot.

EJECTED

Boston Red Sox starting pitcher Eduardo Rodriguez delivers during the first inning of a baseball game against the Oakland Athletics, Wednesday, May 12, 2021, in Boston. (AP PhotoCharles Krupa)

Boston Red Sox starting pitcher Eduardo Rodriguez delivers during the first inning of a baseball game against the Oakland Athletics, Wednesday, May 12, 2021, in Boston. (AP PhotoCharles Krupa)

Oakland center fielder Ramón Laureano was called out on strikes to end the A’s half of the third inning. He remained at the plate arguing as Boston’s players exited. He eventually threw both his batting helmet and bat and was ejected by home plate umpire Ryan Wills.

Laureano made a few steps toward Wills and pointed emphatically at Wills’ face before being restrained by members of the coaching staff. It was the second career ejection for Laureano.

UP NEXT

Oakland Athletics right fielder Stephen Piscotty dives but can't make the play on a double by Boston Red Sox's Marwin Gonzalez during the first inning of a baseball game, Wednesday, May 12, 2021, in Boston. (AP PhotoCharles Krupa)

Oakland Athletics right fielder Stephen Piscotty dives but can't make the play on a double by Boston Red Sox's Marwin Gonzalez during the first inning of a baseball game, Wednesday, May 12, 2021, in Boston. (AP PhotoCharles Krupa)

Athletics: LHP Sean Manaea (3-1, 3.07 ERA) will make his eighth start of the season. He is 3-0 with a 2.23 ERA over his last six starts.

Red Sox: RHP Garrett Richards (2-2, 4.54) has gone at least seven innings in two of his last three starts.

More AP MLB: https://apnews.com/MLB and https://twitter.com/AP_Sports

Oakland Athletics starting pitcher James Kaprielian delivers during the first inning of a baseball game against the Boston Red Sox, Wednesday, May 12, 2021, in Boston. (AP PhotoCharles Krupa)

Oakland Athletics starting pitcher James Kaprielian delivers during the first inning of a baseball game against the Boston Red Sox, Wednesday, May 12, 2021, in Boston. (AP PhotoCharles Krupa)

Oakland Athletics starting pitcher James Kaprielian delivers during the first inning of a baseball game against the Boston Red Sox, Wednesday, May 12, 2021, in Boston. (AP PhotoCharles Krupa)

Oakland Athletics starting pitcher James Kaprielian delivers during the first inning of a baseball game against the Boston Red Sox, Wednesday, May 12, 2021, in Boston. (AP PhotoCharles Krupa)