At least two shooters opened fire on a party bus driving on a San Francisco Bay Area freeway early Tuesday, killing two women and wounding at least five others, authorities said.

The passengers were celebrating a woman’s 21st birthday when the bus was attacked around 12:20 a.m. on Interstate 580 as it was returning to Oakland from San Francisco, the East Bay Times reported.

At least two shooters in another vehicle began firing at the bus, then followed it off the freeway and continued shooting at it on city streets, authorities said. About 70 rounds were fired at the party bus.

Paramedics and police officers respond to a shooting on a party bus that left two people dead and more wounded in East Oakland, Calif., on Tuesday, May 18, 2021. Someone opened fire on a party bus on a San Francisco Bay Area freeway early Tuesday, killing two women and wounding at least five others, authorities said. The passengers were celebrating a woman's 21st birthday when the bus was attacked on Interstate 580 as it was returning to Oakland from San Francisco, the East Bay Times reported. (Dylan BouscherBay Area News Group via AP)

Paramedics and police officers respond to a shooting on a party bus that left two people dead and more wounded in East Oakland, Calif., on Tuesday, May 18, 2021. Someone opened fire on a party bus on a San Francisco Bay Area freeway early Tuesday, killing two women and wounding at least five others, authorities said. The passengers were celebrating a woman's 21st birthday when the bus was attacked on Interstate 580 as it was returning to Oakland from San Francisco, the East Bay Times reported. (Dylan BouscherBay Area News Group via AP)

“Based on preliminary investigation, it does not appear this shooting was a random event,” according to the California Highway Patrol, which is investigating along with Oakland police.

The Alameda County Coroner’s Bureau said one woman died on the bus and the other at a hospital. One of them was a 19-year-old Stockton resident, relatives told the newspaper.

At least five other women were wounded, and some were taken by ambulance to a hospital from an Oakland police station, where the bus driver went after the shooting. One of the victims is in critical condition.

A man who identified himself as the father of the 21-year-old celebrating her birthday said she was shot in the leg but is in stable condition.

Last month, a 25-year-old woman was shot while riding on a party bus in Oakland. There were more than 30 passengers on the bus that was supposed to go to San Francisco, authorities said. None of the other passengers or the driver were injured, and the woman survived.