Vladimir Guerrero Jr. hit his major-league leading 23rd homer and later capped Toronto’s ninth-inning rally with a go-ahead, two-run double, and the Blue Jays ended a five-game skid with a 10-7 victory Saturday over the Baltimore Orioles.

Marcus Semien homered twice for Toronto, which scored six runs in the ninth off relievers Paul Fry and Tyler Wells to stun the Orioles.

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Baltimore Orioles' Freddy Galvis, left, is restrained by Toronto Blue Jays first base Vladimir Guerrero Jr. during a benches-clearing argument in the fourth inning of a baseball game, Saturday, June 19, 2021, in Baltimore. The incident happened as a result of Blue Jays' starting pitcher Alek Manoah hitting Orioles' Maikel Franco with a pitch after Manoah gave up back-to-back home runs to Ryan Mountcastle and DJ Stewart. (AP PhotoJulio Cortez)

Vladimir Guerrero Jr. hit his major-league leading 23rd homer and later capped Toronto’s ninth-inning rally with a go-ahead, two-run double, and the Blue Jays ended a five-game skid with a 10-7 victory Saturday over the Baltimore Orioles.
Toronto Blue Jays starting pitcher Alek Manoah, right, talks with umpires, from left, Jerry Meals, Vic Carapazza and Jansen Visconti after Manoah was ejected in the fourth inning of a baseball game against the Baltimore Orioles, Saturday, June 19, 2021, in Baltimore. The incident happened as a result of Manoah hitting Orioles' Maikel Franco with a pitch after Manoah gave up back-to-back home runs to Ryan Mountcastle and DJ Stewart. (AP PhotoJulio Cortez)

Toronto starter Alek Manoah was ejected for hitting Maikel Franco after surrendering back-to-back blasts in the fourth inning and instigating a benches-clearing incident in which no punches were thrown.
Baltimore Orioles' DJ Stewart follows through as he hits a solo home run off Toronto Blue Jays starting pitcher Alek Manoah during the fourth inning of a baseball game, Saturday, June 19, 2021, in Baltimore. (AP PhotoJulio Cortez)

Manoah gave up a two-run shot to Mountcastle and a solo homer to DJ Stewart in the fourth to give Baltimore a 5-2 lead. He then plunked Franco on the first pitch, prompting the benches and bullpens to empty. Once the situation cooled down, the umpires conferred and ejected Manoah.
Baltimore Orioles manager Brandon Hyde (18) talks with home plate umpire Roberto Ortiz, center left, as members of the Orioles and Toronto Blue Jays engage in a benches-clearing argument after Blue Jays' Alek Manoah hit Orioles' Maikel Franco with a pitch during the fourth inning of a baseball game, Saturday, June 19, 2021, in Baltimore. The hit by a pitch came after Manoah gave up back-to-back home runs to Orioles' Ryan Mountcastle and DJ Stewart, which prompted the argument. (AP PhotoJulio Cortez)

Mountcastle, who also had solo blasts in the second and sixth, is the first Oriole with three homers in a game since Pedro Severino did it at Texas on June 4, 2019. He became the second Orioles rookie with a three-homer game — Nick Markakis was the first, doing so Aug. 22, 2006, against Minnesota.
Baltimore Orioles' Cedric Mullins gestures after hitting a solo home run off Toronto Blue Jays starting pitcher Anthony Kay during the seventh inning of a baseball game, Saturday, June 19, 2021, in Baltimore. (AP PhotoJulio Cortez)

Blue Jays: OF Lourdes Gurriel Jr. pinch hit in the seventh inning and remained in the game to play left a day after exiting for a pinch hitter in the ninth inning with a back injury.
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Baltimore Orioles' Freddy Galvis, left, is restrained by Toronto Blue Jays first base Vladimir Guerrero Jr. during a benches-clearing argument in the fourth inning of a baseball game, Saturday, June 19, 2021, in Baltimore. The incident happened as a result of Blue Jays' starting pitcher Alek Manoah hitting Orioles' Maikel Franco with a pitch after Manoah gave up back-to-back home runs to Ryan Mountcastle and DJ Stewart. (AP PhotoJulio Cortez)

Vladimir Guerrero Jr. hit his major-league leading 23rd homer and later capped Toronto’s ninth-inning rally with a go-ahead, two-run double, and the Blue Jays ended a five-game skid with a 10-7 victory Saturday over the Baltimore Orioles.

Toronto Blue Jays starting pitcher Alek Manoah, right, talks with umpires, from left, Jerry Meals, Vic Carapazza and Jansen Visconti after Manoah was ejected in the fourth inning of a baseball game against the Baltimore Orioles, Saturday, June 19, 2021, in Baltimore. The incident happened as a result of Manoah hitting Orioles' Maikel Franco with a pitch after Manoah gave up back-to-back home runs to Ryan Mountcastle and DJ Stewart. (AP PhotoJulio Cortez)

Toronto starter Alek Manoah was ejected for hitting Maikel Franco after surrendering back-to-back blasts in the fourth inning and instigating a benches-clearing incident in which no punches were thrown.

Baltimore Orioles' DJ Stewart follows through as he hits a solo home run off Toronto Blue Jays starting pitcher Alek Manoah during the fourth inning of a baseball game, Saturday, June 19, 2021, in Baltimore. (AP PhotoJulio Cortez)

Manoah gave up a two-run shot to Mountcastle and a solo homer to DJ Stewart in the fourth to give Baltimore a 5-2 lead. He then plunked Franco on the first pitch, prompting the benches and bullpens to empty. Once the situation cooled down, the umpires conferred and ejected Manoah.

Baltimore Orioles manager Brandon Hyde (18) talks with home plate umpire Roberto Ortiz, center left, as members of the Orioles and Toronto Blue Jays engage in a benches-clearing argument after Blue Jays' Alek Manoah hit Orioles' Maikel Franco with a pitch during the fourth inning of a baseball game, Saturday, June 19, 2021, in Baltimore. The hit by a pitch came after Manoah gave up back-to-back home runs to Orioles' Ryan Mountcastle and DJ Stewart, which prompted the argument. (AP PhotoJulio Cortez)

Mountcastle, who also had solo blasts in the second and sixth, is the first Oriole with three homers in a game since Pedro Severino did it at Texas on June 4, 2019. He became the second Orioles rookie with a three-homer game — Nick Markakis was the first, doing so Aug. 22, 2006, against Minnesota.

Baltimore Orioles' Cedric Mullins gestures after hitting a solo home run off Toronto Blue Jays starting pitcher Anthony Kay during the seventh inning of a baseball game, Saturday, June 19, 2021, in Baltimore. (AP PhotoJulio Cortez)

Blue Jays: OF Lourdes Gurriel Jr. pinch hit in the seventh inning and remained in the game to play left a day after exiting for a pinch hitter in the ninth inning with a back injury.

Ryan Mountcastle recorded his first career three-homer game and Cedric Mullins had his second consecutive multihomer game for Baltimore, which hit six homers in a game for the first time since doing so against Houston on Aug. 18, 2016.

Baltimore Orioles' Freddy Galvis, left, is restrained by Toronto Blue Jays first base Vladimir Guerrero Jr. during a benches-clearing argument in the fourth inning of a baseball game, Saturday, June 19, 2021, in Baltimore. The incident happened as a result of Blue Jays' starting pitcher Alek Manoah hitting Orioles' Maikel Franco with a pitch after Manoah gave up back-to-back home runs to Ryan Mountcastle and DJ Stewart. (AP PhotoJulio Cortez)

Baltimore Orioles' Freddy Galvis, left, is restrained by Toronto Blue Jays first base Vladimir Guerrero Jr. during a benches-clearing argument in the fourth inning of a baseball game, Saturday, June 19, 2021, in Baltimore. The incident happened as a result of Blue Jays' starting pitcher Alek Manoah hitting Orioles' Maikel Franco with a pitch after Manoah gave up back-to-back home runs to Ryan Mountcastle and DJ Stewart. (AP PhotoJulio Cortez)

Toronto starter Alek Manoah was ejected for hitting Maikel Franco after surrendering back-to-back blasts in the fourth inning and instigating a benches-clearing incident in which no punches were thrown.

Staked to a 7-4 lead to start the ninth, Fry (0-2) allowed two walks and two hits while recording two outs. Wells entered with the bases loaded and a 7-5 lead, but Bo Bichette blooped a two-run single to right to tie it. Guerrero then laced a double into the left-center gap to give the Blue Jays a 9-7 lead, and he scored on Randal Grichuk’s ensuing double.

Jordan Romano (4-1) pitched two scoreless innings for Toronto.

Toronto Blue Jays starting pitcher Alek Manoah, right, talks with umpires, from left, Jerry Meals, Vic Carapazza and Jansen Visconti after Manoah was ejected in the fourth inning of a baseball game against the Baltimore Orioles, Saturday, June 19, 2021, in Baltimore. The incident happened as a result of Manoah hitting Orioles' Maikel Franco with a pitch after Manoah gave up back-to-back home runs to Ryan Mountcastle and DJ Stewart. (AP PhotoJulio Cortez)

Toronto Blue Jays starting pitcher Alek Manoah, right, talks with umpires, from left, Jerry Meals, Vic Carapazza and Jansen Visconti after Manoah was ejected in the fourth inning of a baseball game against the Baltimore Orioles, Saturday, June 19, 2021, in Baltimore. The incident happened as a result of Manoah hitting Orioles' Maikel Franco with a pitch after Manoah gave up back-to-back home runs to Ryan Mountcastle and DJ Stewart. (AP PhotoJulio Cortez)

Manoah gave up a two-run shot to Mountcastle and a solo homer to DJ Stewart in the fourth to give Baltimore a 5-2 lead. He then plunked Franco on the first pitch, prompting the benches and bullpens to empty. Once the situation cooled down, the umpires conferred and ejected Manoah.

Manoah allowed five runs in 3 1/3 innings, striking out six.

Baltimore starter Dean Kremer yielded solo shots to Semien and Guerrero in the first but no other damage over six innings, striking out six.

Baltimore Orioles' DJ Stewart follows through as he hits a solo home run off Toronto Blue Jays starting pitcher Alek Manoah during the fourth inning of a baseball game, Saturday, June 19, 2021, in Baltimore. (AP PhotoJulio Cortez)

Baltimore Orioles' DJ Stewart follows through as he hits a solo home run off Toronto Blue Jays starting pitcher Alek Manoah during the fourth inning of a baseball game, Saturday, June 19, 2021, in Baltimore. (AP PhotoJulio Cortez)

Mountcastle, who also had solo blasts in the second and sixth, is the first Oriole with three homers in a game since Pedro Severino did it at Texas on June 4, 2019. He became the second Orioles rookie with a three-homer game — Nick Markakis was the first, doing so Aug. 22, 2006, against Minnesota.

Mullins had solo shots in the third and the seventh a day after going deep twice in the series opener against the Blue Jays.

TRAINER’S ROOM

Baltimore Orioles manager Brandon Hyde (18) talks with home plate umpire Roberto Ortiz, center left, as members of the Orioles and Toronto Blue Jays engage in a benches-clearing argument after Blue Jays' Alek Manoah hit Orioles' Maikel Franco with a pitch during the fourth inning of a baseball game, Saturday, June 19, 2021, in Baltimore. The hit by a pitch came after Manoah gave up back-to-back home runs to Orioles' Ryan Mountcastle and DJ Stewart, which prompted the argument. (AP PhotoJulio Cortez)

Baltimore Orioles manager Brandon Hyde (18) talks with home plate umpire Roberto Ortiz, center left, as members of the Orioles and Toronto Blue Jays engage in a benches-clearing argument after Blue Jays' Alek Manoah hit Orioles' Maikel Franco with a pitch during the fourth inning of a baseball game, Saturday, June 19, 2021, in Baltimore. The hit by a pitch came after Manoah gave up back-to-back home runs to Orioles' Ryan Mountcastle and DJ Stewart, which prompted the argument. (AP PhotoJulio Cortez)

Blue Jays: OF Lourdes Gurriel Jr. pinch hit in the seventh inning and remained in the game to play left a day after exiting for a pinch hitter in the ninth inning with a back injury.

Orioles: Manager Brandon Hyde said he anticipates LHP John Means (shoulder strain) returning “right around” the All-Star break. Means, who left his June 5 start in the first inning and landed on the injured list the next day, has started to play catch.

DEAL

Baltimore Orioles' Cedric Mullins gestures after hitting a solo home run off Toronto Blue Jays starting pitcher Anthony Kay during the seventh inning of a baseball game, Saturday, June 19, 2021, in Baltimore. (AP PhotoJulio Cortez)

Baltimore Orioles' Cedric Mullins gestures after hitting a solo home run off Toronto Blue Jays starting pitcher Anthony Kay during the seventh inning of a baseball game, Saturday, June 19, 2021, in Baltimore. (AP PhotoJulio Cortez)

Toronto acquired RHP Jacob Barnes from the New York Mets for minor league RHP Troy Miller. Barnes was 1-1 with a 6.27 ERA and two saves in 19 appearances for New York before he was designated for assignment Monday.

UP NEXT

Blue Jays: LHP Hyun Jin Ryu (5-4, 3.43 ERA) is 1-0 with a 3.00 ERA in three career starts against Baltimore.

Orioles: RHP Matt Harvey (3-8, 7.76) will attempt to end an eight-start winless streak as the three-game series concludes. Harvey is 0-7 with a 12.00 ERA since May 7.

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