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Studies clash on Russian vaccine's efficacy against omicron

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Studies clash on Russian vaccine's efficacy against omicron
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Studies clash on Russian vaccine's efficacy against omicron

2021-12-17 22:28 Last Updated At:23:00

The developer of Russia’s Sputnik V said Friday that its vaccine provides the best protection against the omicron variant of the coronavirus, disputing a Western study which found Sputnik produced no antibodies against the new variant.

The Gamaleya Institute and the Russian Direct Investment Fund, which bankrolled Sputnik V and its one-shot version called Sputnik Light, said in a statement that a preliminary laboratory study showed Sputnik V had “the best virus neutralization results against omicron in comparison with other vaccines”.

Russian President Vladimir Putin praised Sputnik V efficiency against omicron earlier Friday.

Russian President Vladimir Putin delivers his speech during the Russian Union of Industrialists and Entrepreneurs (RSPP) Congress in Moscow, Russia, Friday, Dec. 17, 2021. (Mikhail Metzel, Sputnik, Kremlin Pool Photo via AP)

Russian President Vladimir Putin delivers his speech during the Russian Union of Industrialists and Entrepreneurs (RSPP) Congress in Moscow, Russia, Friday, Dec. 17, 2021. (Mikhail Metzel, Sputnik, Kremlin Pool Photo via AP)

“Our Sputnik V is working well, and, perhaps, even more effective against the omicron than other vaccines used,” the president said during a congress of the Russian Union of Industrialists and Entrepreneurs.

Meanwhile, international researchers from the University of Washington and the Swiss drugmaker Humabs Biomed SA said in a study published Tuesday in pre-print and yet to be peer-reviewed that data they analyzed showed conflicting results.

The study, which used samples from health care workers in Buenos Aires, Argentina, who received Sputnik V, showed “no neutralizing activity against omicron.”

Russian President Vladimir Putin gestures while speaking at the Russian Union of Industrialists and Entrepreneurs (RSPP) Congress in Moscow, Russia, Friday, Dec. 17, 2021. (Mikhail Metzel, Sputnik, Kremlin Pool Photo via AP)

Russian President Vladimir Putin gestures while speaking at the Russian Union of Industrialists and Entrepreneurs (RSPP) Congress in Moscow, Russia, Friday, Dec. 17, 2021. (Mikhail Metzel, Sputnik, Kremlin Pool Photo via AP)

Russia has so far reported 25 cases of the omicron variant in the country, according to Deputy Prime Minister Tatiana Golikova.

Follow AP's coverage of the pandemic at https://apnews.com/hub/coronavirus-pandemic

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UN approves an updated cholera vaccine that could help fight a surge in cases

2024-04-19 11:59 Last Updated At:12:00

The World Health Organization has approved a version of a widely used cholera vaccine that could help address a surge in cases that has depleted the global vaccine stockpile and left poorer countries scrambling to contain epidemics.

WHO authorized the vaccine, made by EuBiologics, which also makes the formulation now used, last week. The new version, called Euvichol-S, is a simplified formula that uses fewer ingredients, is cheaper, and can be made more quickly than the old version.

The vaccine was shown to be help preventing the diarrheal disease in late stage research conducted in Nepal.

WHO’s approval means donor agencies like the vaccines alliance Gavi and UNICEF can now buy it for poorer countries. Leila Pakkala, director of UNICEF’s supply division, said in a statement that the agency will be able to boost supplies by more than 25%.

Gavi estimated there could be about 50 million doses for the global stockpile this year, compared with 38 million last year.

Dr. Derrick Sim of Gavi called WHO’s authorization “a lifeline for vulnerable communities around the world.”

More is still needed, however: Since January, 14 countries affected by cholera outbreaks have requested 79 million doses. In January, the U.N. agency said the global vaccine stockpile was “entirely depleted” until the beginning of March. As of this week, WHO said there were 2.3 million doses available.

Cholera is an acute diarrhea disease caused by a bacteria typically spread via contaminated food or water. It is mostly seen in areas that have poor sanitation and lack access to clean water. While most people infected with cholera don't experience symptoms, those with severe cases need quick treatment with intravenous fluids and antibiotics. If left untreated, cholera kills about a quarter to half of people infected.

Since last January, WHO has reported more than 824,000 cholera infections, including 5,900 deaths worldwide, with the highest numbers of cases reported in the Middle East and Africa. The U.N. agency said warming temperatures that allow the cholera bacteria to live longer, have also worsened outbreaks and led to the highest death rates in a decade.

The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Science and Educational Media Group. The AP is solely responsible for all content.

FILE - A family enters a tent set aside for cholera patients at a clinic in Harare, Zimbabwe, on Nov. 18, 2023. The World Health Organization has approved a new version of a widely used cholera vaccine that could help address a surge in cases that has depleted the global vaccine stockpile. In a decision last week, WHO authorized a new vaccine by EuBiologics, the only maker of the oral cholera vaccine for a global stockpile managed by the U.N. health agency and partners. (AP Photo/Tsvangirayi Mukwazhi, File)

FILE - A family enters a tent set aside for cholera patients at a clinic in Harare, Zimbabwe, on Nov. 18, 2023. The World Health Organization has approved a new version of a widely used cholera vaccine that could help address a surge in cases that has depleted the global vaccine stockpile. In a decision last week, WHO authorized a new vaccine by EuBiologics, the only maker of the oral cholera vaccine for a global stockpile managed by the U.N. health agency and partners. (AP Photo/Tsvangirayi Mukwazhi, File)

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