SAN FRANCISCO (11-7) at GREEN BAY (13-4)

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FILE -San Francisco 49ers running back Trey Sermon, middle, runs for a touchdown against the Green Bay Packers during the second half of an NFL football game in Santa Clara, Calif., Sunday, Sept. 26, 2021. The Packers and 49er meet Saturday, Jan. 22, 2022.(AP PhotoJed Jacobsohn, File)

SAN FRANCISCO (11-7) at GREEN BAY (13-4)

FILE -Green Bay Packers kicker Mason Crosby (2) kicks the game winning field goal from the hold of Corey Bojorquez during the second half of an NFL football game against the San Francisco 49ers in Santa Clara, Calif., Sunday, Sept. 26, 2021. The Packers and 49er meet Saturday, Jan. 22, 2022.(AP PhotoJed Jacobsohn, File)

LAST MEETING: Packers beat 49ers 30-28 on Sept. 26, in Santa Clara, California.

San Francisco 49ers defensive end Charles Omenihu (92) celebrates after sacking Dallas Cowboys quarterback Dak Prescott (4) during the second half of an NFL wild-card playoff football game in Arlington, Texas, Sunday, Jan. 16, 2022. (Smiley N. PoolThe Dallas Morning News via AP)

49ERS DEFENSE: OVERALL (3), RUSH (6), PASS (6), SCORING (8).

FILE - Green Bay Packers' Davante Adams, left, celebrates his touchdown reception with Aaron Rodgers during the first half of an NFL football game against the Cleveland Browns Saturday, Dec. 25, 2021, in Green Bay, Wis. Until this season, Green Bay Packers quarterback Aaron Rodgers always referred to Hall of Fame cornerback Charles Woodson as his greatest teammate ever. After a Christmas Day victory over the Cleveland Browns, Rodgers called Adams the “most dominant player I’ve played with.” (AP PhotoMatt Ludtke, File)

49ERS PLAYER TO WATCH: WR Deebo Samuel. The All-Pro wideout had a season-low 52 yards from scrimmage – including zero yards rushing - against the Packers back in September but has since emerged as much more of a multipurpose threat. He had 1,405 yards receiving, 365 yards rushing and 14 total touchdowns in the regular season. Samuel rushed for 72 yards and a touchdown on 10 carries and also had three catches for 38 yards against Dallas.

Green Bay Packers running back A.J. Dillon (28) rushes during the second half of an NFL football game against the Detroit Lions, Sunday, Jan. 9, 2022, in Detroit. (AP PhotoDuane Burleson)

KEY INJURIES: Bosa (concussion), CB Ambry Thomas (knee) and DE Jordan Willis (ankle) are all questionable for the 49ers. ... QB Jimmy Garoppolo (shoulder, thumb) and LB Fred Warner are set to play despite dealing with injuries. ... Bakhtiari (knee) and CB Jaire Alexander (shoulder) are questionable and WR Marquez Valdes-Scantling (back) is doubtful. … Packers OT Billy Turner (knee) and WR Randall Cobb (core) are expected to return from injuries Saturday. ... Packers TE Robert Tonyan and OL Elgton Jenkins are out for the season with knee injuries.

OPENING LINE: Packers by 6, according to FanDuel Sportsbook.

AGAINST THE SPREAD: 49ers 10-8; Packers 12-5.

SERIES RECORD: Packers lead 38-32-1

FILE -San Francisco 49ers running back Trey Sermon, middle, runs for a touchdown against the Green Bay Packers during the second half of an NFL football game in Santa Clara, Calif., Sunday, Sept. 26, 2021. The Packers and 49er meet Saturday, Jan. 22, 2022.(AP PhotoJed Jacobsohn, File)

FILE -San Francisco 49ers running back Trey Sermon, middle, runs for a touchdown against the Green Bay Packers during the second half of an NFL football game in Santa Clara, Calif., Sunday, Sept. 26, 2021. The Packers and 49er meet Saturday, Jan. 22, 2022.(AP PhotoJed Jacobsohn, File)

LAST MEETING: Packers beat 49ers 30-28 on Sept. 26, in Santa Clara, California.

LAST WEEK: 49ers won 23-17 at Dallas on Sunday; Packers had bye, lost to Lions 37-30.

49ERS OFFENSE: OVERALL (7), RUSH (7), PASS (12), SCORING (13-T).

FILE -Green Bay Packers kicker Mason Crosby (2) kicks the game winning field goal from the hold of Corey Bojorquez during the second half of an NFL football game against the San Francisco 49ers in Santa Clara, Calif., Sunday, Sept. 26, 2021. The Packers and 49er meet Saturday, Jan. 22, 2022.(AP PhotoJed Jacobsohn, File)

FILE -Green Bay Packers kicker Mason Crosby (2) kicks the game winning field goal from the hold of Corey Bojorquez during the second half of an NFL football game against the San Francisco 49ers in Santa Clara, Calif., Sunday, Sept. 26, 2021. The Packers and 49er meet Saturday, Jan. 22, 2022.(AP PhotoJed Jacobsohn, File)

49ERS DEFENSE: OVERALL (3), RUSH (6), PASS (6), SCORING (8).

PACKERS OFFENSE: OVERALL (9), RUSH (21), PASS (11), SCORING (13).

PACKERS DEFENSE: OVERALL (9), RUSH (12), PASS (9), SCORING (13).

TURNOVER DIFFERENTIAL: 49ers minus-4; Packers plus-13

San Francisco 49ers defensive end Charles Omenihu (92) celebrates after sacking Dallas Cowboys quarterback Dak Prescott (4) during the second half of an NFL wild-card playoff football game in Arlington, Texas, Sunday, Jan. 16, 2022. (Smiley N. PoolThe Dallas Morning News via AP)

San Francisco 49ers defensive end Charles Omenihu (92) celebrates after sacking Dallas Cowboys quarterback Dak Prescott (4) during the second half of an NFL wild-card playoff football game in Arlington, Texas, Sunday, Jan. 16, 2022. (Smiley N. PoolThe Dallas Morning News via AP)

49ERS PLAYER TO WATCH: WR Deebo Samuel. The All-Pro wideout had a season-low 52 yards from scrimmage – including zero yards rushing - against the Packers back in September but has since emerged as much more of a multipurpose threat. He had 1,405 yards receiving, 365 yards rushing and 14 total touchdowns in the regular season. Samuel rushed for 72 yards and a touchdown on 10 carries and also had three catches for 38 yards against Dallas.

PACKERS PLAYER TO WATCH: QB Aaron Rodgers. He threw 20 touchdown passes without an interception over his final seven games to emerge as a favorite to win his fourth MVP award. Now he has a chance to improve upon his so-so 11-9 playoff record as a starter, which includes an 0-3 mark against the 49ers.

KEY MATCHUP: Packers OT David Bakhtiari vs. 49ers DE Nick Bosa. This is based on the assumption that both these guys actually play. Bakhtiari, a 2020 All-Pro, tore his anterior cruciate ligament on Dec. 31, 2020, and finally returned to action by playing 27 snaps in the Packers’ regular-season finale. The Packers have been cautious with him in practice the last couple of weeks. Bosa, who recorded 15 ½ sacks during the regular season, sustained a concussion against Dallas. Bosa has 4 ½ sacks in four career playoff games.

FILE - Green Bay Packers' Davante Adams, left, celebrates his touchdown reception with Aaron Rodgers during the first half of an NFL football game against the Cleveland Browns Saturday, Dec. 25, 2021, in Green Bay, Wis. Until this season, Green Bay Packers quarterback Aaron Rodgers always referred to Hall of Fame cornerback Charles Woodson as his greatest teammate ever. After a Christmas Day victory over the Cleveland Browns, Rodgers called Adams the “most dominant player I’ve played with.” (AP PhotoMatt Ludtke, File)

FILE - Green Bay Packers' Davante Adams, left, celebrates his touchdown reception with Aaron Rodgers during the first half of an NFL football game against the Cleveland Browns Saturday, Dec. 25, 2021, in Green Bay, Wis. Until this season, Green Bay Packers quarterback Aaron Rodgers always referred to Hall of Fame cornerback Charles Woodson as his greatest teammate ever. After a Christmas Day victory over the Cleveland Browns, Rodgers called Adams the “most dominant player I’ve played with.” (AP PhotoMatt Ludtke, File)

KEY INJURIES: Bosa (concussion), CB Ambry Thomas (knee) and DE Jordan Willis (ankle) are all questionable for the 49ers. ... QB Jimmy Garoppolo (shoulder, thumb) and LB Fred Warner are set to play despite dealing with injuries. ... Bakhtiari (knee) and CB Jaire Alexander (shoulder) are questionable and WR Marquez Valdes-Scantling (back) is doubtful. … Packers OT Billy Turner (knee) and WR Randall Cobb (core) are expected to return from injuries Saturday. ... Packers TE Robert Tonyan and OL Elgton Jenkins are out for the season with knee injuries.

SERIES NOTES: The Packers and 49ers have split eight previous playoff matchups. The 49ers have won the last three postseason meetings, including a 37-20 victory in the NFC championship game two seasons ago. … The 49ers have hosted the Packers in the regular season each of the last three years. The Packers won 30-28 this year on Mason Crosby’s 51-yard field goal as time expired and won 34-17 last season. The 49ers won 37-8 in 2019. … This marks the first time the Packers and 49ers have faced off in Lambeau Field since the Packers won 33-30 on Oct. 15, 2018.

STATS AND STUFF: The winner of this game faces either the Tampa Bay Buccaneers or Los Angeles Rams in the NFC championship game. The Packers would play the NFC championship game at home, while the 49ers would have to go back on the road. … The 49ers are coming off a five-sack performance against Dallas. Charles Omenihu had 1 ½ sacks in that game. … 49ers K Robbie Gould is 18 of 18 in career playoff field-goal attempts, the most makes ever in the postseason without a miss. Gould made kicks of 53, 52 and 40 yards against Dallas. … The 49ers have won their last four divisional-round playoff games (during the 2011, 2012, 2013 and 2019 seasons). Three of the four wins were at home. Their last loss in this round was a 31-6 defeat at Tampa Bay during the 2002 season. … The Niners have averaged 195.3 yards rushing per game in four playoff games under coach Kyle Shanahan. ... San Francisco QB Jimmy Garoppolo has averaged 149.8 yards passing per game with four INTs and two TDs in four playoff starts. ... The Packers are seeking to reach the NFC championship game for a third straight season. They haven’t made it to the Super Bowl since their 2010 championship season. … The last two times he has faced the 49ers, Packers WR Davante Adams has caught a total of 22 passes for 305 yards. He has scored a touchdown in each of those games. … Rodgers has thrown multiple touchdown passes in an NFL-record nine straight playoff games. … The Packers are 11-10 in divisional playoff games, including an 8-1 home record. The home loss came to the eventual Super Bowl champion New York Giants in the 2011 season. … The 49ers are 33-21 and the Packers are 36-24 in postseason games. Only the New England Patriots (37-22) have a better postseason winning percentage. The Packers’ 36 postseason wins put them in a tie for second place with the Pittsburgh Steelers, one behind New England. … 49ers coach Kyle Shanahan and Packers coach Matt LaFleur worked together as NFL assistants with Houston, Washington and Atlanta.

Green Bay Packers running back A.J. Dillon (28) rushes during the second half of an NFL football game against the Detroit Lions, Sunday, Jan. 9, 2022, in Detroit. (AP PhotoDuane Burleson)

Green Bay Packers running back A.J. Dillon (28) rushes during the second half of an NFL football game against the Detroit Lions, Sunday, Jan. 9, 2022, in Detroit. (AP PhotoDuane Burleson)

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