Raimel Tapia hit a go-ahead, two-run homer in a five-run second inning for his first RBIs this season, and the Toronto Blue Jays beat the Boston Red Sox 6-1 Wednesday night.

José Berríos (1-0) won for the first time in three starts this season, allowing one run and eight hits in six innings with six strikeouts and one walk. He lowered his ERA from 11.81 to 6.35.

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Toronto Blue Jays' Raimel Tapia, right, is congratulated by Matt Chapman after his two-run home run during the second inning of the team's baseball game against the Boston Red Sox, Wednesday, April 20, 2022, at Fenway Park in Boston. (AP PhotoCharles Krupa)

Raimel Tapia hit a go-ahead, two-run homer in a five-run second inning for his first RBIs this season, and the Toronto Blue Jays beat the Boston Red Sox 6-1 Wednesday night.

Boston Red Sox's Trevor Story puts his helmet back on after getting hit on the helmet by a pitch thrown by Toronto Blue Jays starting pitcher Jose Berrios during the third inning of a baseball game Wednesday, April 20, 2022, at Fenway Park in Boston. Story stayed in the game. (AP PhotoCharles Krupa)

Left-hander Tim Mayza got two outs while allowing two hits, and right-handers Trevor Richards and Julian Merryweather combined for 2 1/3 hitless innings.

Toronto Blue Jays' George Springer is examined after he was hit by a pitch during the sixth inning of the team's baseball game against the Boston Red Sox, Wednesday, April 20, 2022, at Fenway Park in Boston. (AP PhotoCharles Krupa)

Matt Chapman singled leading off the second, and Tapia homered to right for a 2-1 lead. Pivetta walked Santiago Espinal on a full count and Alejandro Kirk on four pitches, and Cavan Biggio's single loaded the bases.

Boston Red Sox second baseman Trevor Story, left, misses the throw as Toronto Blue Jays' Lourdes Gurriel Jr. (13) steals second base during the seventh inning of a baseball game Wednesday, April 20, 2022, at Fenway Park in Boston. (AP PhotoCharles Krupa)

REMEMBERING REMY

Boston Red Sox starting pitcher Nick Pivetta passes Toronto Blue Jays' Vladimir Guerrero Jr., left, while walking back to the mound during the second inning of a baseball game, Wednesday, April 20, 2022, at Fenway Park in Boston. Pivetta allowed five earned runs in the inning. (AP PhotoCharles Krupa)

Blue Jays: After being hit by a pitch from Phillips Valdéz in the sixth, Springer left in the bottom of the inning with a bruised right forearm. X-rays were negative.

Boston Red Sox's Trevor Story hits the dirt after getting hit on the helmet by a pitch thrown by Toronto Blue Jays' Jose Berrios during the third inning of a baseball game Wednesday, April 20, 2022, at Fenway Park in Boston. Story stayed in the game. (AP PhotoCharles Krupa)

Blue Jays: RHP Kevin Gausman (0-1, 4.22 ERA) is scheduled to start the series finale on Thursday. He is 4-8 with a 4.53 ERA in 20 games against the Red Sox, but has not faced them since 2018 while with Baltimore. In 11 games at Fenway Park, he is 2-4 with a 4.57 ERA.

Boston Red Sox's Trevor Story kneels after after getting hit on the helmet by a pitch thrown by Toronto Blue Jays' Jose Berrios during the third inning of a baseball game Wednesday, April 20, 2022, at Fenway Park in Boston. Story stayed in the game. At left is manager Alex Cora. (AP PhotoCharles Krupa)

Boston Red Sox's Trevor Story kneels after after getting hit on the helmet by a pitch thrown by Toronto Blue Jays' Jose Berrios during the third inning of a baseball game Wednesday, April 20, 2022, at Fenway Park in Boston. Story stayed in the game. At left is manager Alex Cora. (AP PhotoCharles Krupa)

Toronto Blue Jays' Raimel Tapia, right, is congratulated by Matt Chapman after his two-run home run during the second inning of the team's baseball game against the Boston Red Sox, Wednesday, April 20, 2022, at Fenway Park in Boston. (AP PhotoCharles Krupa)

Toronto Blue Jays' Raimel Tapia, right, is congratulated by Matt Chapman after his two-run home run during the second inning of the team's baseball game against the Boston Red Sox, Wednesday, April 20, 2022, at Fenway Park in Boston. (AP PhotoCharles Krupa)

Left-hander Tim Mayza got two outs while allowing two hits, and right-handers Trevor Richards and Julian Merryweather combined for 2 1/3 hitless innings.

Nick Pivetta (0-3) gave up five runs, seven hits and four walks in four innings. His ERA rose from 9.39 to 10.03, and the 29-year-old Canadian right-hander failed to reach the fifth inning for his second straight start.

J.D. Martinez had an RBI single in the first that drove in Rafael Devers, who had doubled. Martinez left with left adductor tightness after doubling to lead off the third.

Boston Red Sox's Trevor Story puts his helmet back on after getting hit on the helmet by a pitch thrown by Toronto Blue Jays starting pitcher Jose Berrios during the third inning of a baseball game Wednesday, April 20, 2022, at Fenway Park in Boston. Story stayed in the game. (AP PhotoCharles Krupa)

Boston Red Sox's Trevor Story puts his helmet back on after getting hit on the helmet by a pitch thrown by Toronto Blue Jays starting pitcher Jose Berrios during the third inning of a baseball game Wednesday, April 20, 2022, at Fenway Park in Boston. Story stayed in the game. (AP PhotoCharles Krupa)

Matt Chapman singled leading off the second, and Tapia homered to right for a 2-1 lead. Pivetta walked Santiago Espinal on a full count and Alejandro Kirk on four pitches, and Cavan Biggio's single loaded the bases.

George Springer hit a sacrifice fly, and Bo Bichette followed with a two-run single for a 5-1 lead.

Espinal added a seventh-inning sacrifice fly. Lourdes Gurriel Jr. and Tapia stole bases in the inning after Toronto entered with three this season.

Toronto Blue Jays' George Springer is examined after he was hit by a pitch during the sixth inning of the team's baseball game against the Boston Red Sox, Wednesday, April 20, 2022, at Fenway Park in Boston. (AP PhotoCharles Krupa)

Toronto Blue Jays' George Springer is examined after he was hit by a pitch during the sixth inning of the team's baseball game against the Boston Red Sox, Wednesday, April 20, 2022, at Fenway Park in Boston. (AP PhotoCharles Krupa)

REMEMBERING REMY

The Red Sox honored former second baseman Jerry Remy in a pregame ceremony. Remy, a native of Somerset, Massachusetts, made his major league debut with the California Angels in 1975 before spending more than 40 years with the Red Sox organization as a player, coach and broadcaster. He died on October 30 after a lengthy battle with lung cancer. Former Red Sox teammates Fred Lynn, Dwight Evans, Bob Stanley, Rick Burleson and Hall of Famers Jim Rice, Dennis Eckersley and Carl Yastrzemski were in attendance.

TRAINER’S ROOM

Boston Red Sox second baseman Trevor Story, left, misses the throw as Toronto Blue Jays' Lourdes Gurriel Jr. (13) steals second base during the seventh inning of a baseball game Wednesday, April 20, 2022, at Fenway Park in Boston. (AP PhotoCharles Krupa)

Boston Red Sox second baseman Trevor Story, left, misses the throw as Toronto Blue Jays' Lourdes Gurriel Jr. (13) steals second base during the seventh inning of a baseball game Wednesday, April 20, 2022, at Fenway Park in Boston. (AP PhotoCharles Krupa)

Blue Jays: After being hit by a pitch from Phillips Valdéz in the sixth, Springer left in the bottom of the inning with a bruised right forearm. X-rays were negative.

Red Sox: C Christian Vázquez was reinstated from the COVID-19 related injury list, where he was placed before Monday’s game. C Ronaldo Hernandez was optioned to Triple-A Worcester. ... 2B Trevor Story was hit on the helmet by a Berrios pitch in the third inning but stayed in the game.

UP NEXT

Boston Red Sox starting pitcher Nick Pivetta passes Toronto Blue Jays' Vladimir Guerrero Jr., left, while walking back to the mound during the second inning of a baseball game, Wednesday, April 20, 2022, at Fenway Park in Boston. Pivetta allowed five earned runs in the inning. (AP PhotoCharles Krupa)

Boston Red Sox starting pitcher Nick Pivetta passes Toronto Blue Jays' Vladimir Guerrero Jr., left, while walking back to the mound during the second inning of a baseball game, Wednesday, April 20, 2022, at Fenway Park in Boston. Pivetta allowed five earned runs in the inning. (AP PhotoCharles Krupa)

Blue Jays: RHP Kevin Gausman (0-1, 4.22 ERA) is scheduled to start the series finale on Thursday. He is 4-8 with a 4.53 ERA in 20 games against the Red Sox, but has not faced them since 2018 while with Baltimore. In 11 games at Fenway Park, he is 2-4 with a 4.57 ERA.

Red Sox: RHP Tanner Houck (1-0, 3.00) will make his third start of the season. This will also be his third career start against the Blue Jays. He has a 2.35 ERA against Toronto, without a decision.

More AP baseball: https://apnews.com/hub/MLB and https://twitter.com/AP_Sports

Boston Red Sox's Trevor Story hits the dirt after getting hit on the helmet by a pitch thrown by Toronto Blue Jays' Jose Berrios during the third inning of a baseball game Wednesday, April 20, 2022, at Fenway Park in Boston. Story stayed in the game. (AP PhotoCharles Krupa)

Boston Red Sox's Trevor Story hits the dirt after getting hit on the helmet by a pitch thrown by Toronto Blue Jays' Jose Berrios during the third inning of a baseball game Wednesday, April 20, 2022, at Fenway Park in Boston. Story stayed in the game. (AP PhotoCharles Krupa)

Boston Red Sox's Trevor Story kneels after after getting hit on the helmet by a pitch thrown by Toronto Blue Jays' Jose Berrios during the third inning of a baseball game Wednesday, April 20, 2022, at Fenway Park in Boston. Story stayed in the game. At left is manager Alex Cora. (AP PhotoCharles Krupa)

Boston Red Sox's Trevor Story kneels after after getting hit on the helmet by a pitch thrown by Toronto Blue Jays' Jose Berrios during the third inning of a baseball game Wednesday, April 20, 2022, at Fenway Park in Boston. Story stayed in the game. At left is manager Alex Cora. (AP PhotoCharles Krupa)