The World Health Organization has approved a version of a widely used cholera vaccine that could help address a surge in cases that has depleted the global vaccine stockpile and left poorer countries scrambling to contain epidemics.
WHO authorized the vaccine, made by EuBiologics, which also makes the formulation now used, last week. The new version, called Euvichol-S, is a simplified formula that uses fewer ingredients, is cheaper, and can be made more quickly than the old version.
The vaccine was shown to be help preventing the diarrheal disease in late stage research conducted in Nepal.
WHO’s approval means donor agencies like the vaccines alliance Gavi and UNICEF can now buy it for poorer countries. Leila Pakkala, director of UNICEF’s supply division, said in a statement that the agency will be able to boost supplies by more than 25%.
Gavi estimated there could be about 50 million doses for the global stockpile this year, compared with 38 million last year.
Dr. Derrick Sim of Gavi called WHO’s authorization “a lifeline for vulnerable communities around the world.”
More is still needed, however: Since January, 14 countries affected by cholera outbreaks have requested 79 million doses. In January, the U.N. agency said the global vaccine stockpile was “entirely depleted” until the beginning of March. As of this week, WHO said there were 2.3 million doses available.
Cholera is an acute diarrhea disease caused by a bacteria typically spread via contaminated food or water. It is mostly seen in areas that have poor sanitation and lack access to clean water. While most people infected with cholera don't experience symptoms, those with severe cases need quick treatment with intravenous fluids and antibiotics. If left untreated, cholera kills about a quarter to half of people infected.
Since last January, WHO has reported more than 824,000 cholera infections, including 5,900 deaths worldwide, with the highest numbers of cases reported in the Middle East and Africa. The U.N. agency said warming temperatures that allow the cholera bacteria to live longer, have also worsened outbreaks and led to the highest death rates in a decade.
The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Science and Educational Media Group. The AP is solely responsible for all content.
FILE - A family enters a tent set aside for cholera patients at a clinic in Harare, Zimbabwe, on Nov. 18, 2023. The World Health Organization has approved a new version of a widely used cholera vaccine that could help address a surge in cases that has depleted the global vaccine stockpile. In a decision last week, WHO authorized a new vaccine by EuBiologics, the only maker of the oral cholera vaccine for a global stockpile managed by the U.N. health agency and partners. (AP Photo/Tsvangirayi Mukwazhi, File)
BLAINE, Minn. (AP) — Taylor Pendrith shot a 7-under 64 on Friday to take a two-stroke lead over Matt NeSmith into the weekend in the 3M Open.
Playing in windier afternoon conditions, Pendrith made a 30-foot birdie putt on the par-4 16th and tapped in for another birdie on the par-5 18th. He had a 12-under 130 total at the TPC Twin Cities, playing the first 36 holes without a bogey.
The 33-year-old Canadian won the CJ Cup Byron Nelson in May in Texas for his first PGA Tour title. He tied for fifth last week in the Barracuda Championship in California.
“Today was pretty tricky with the wind, it was blowing pretty hard at times, so my speed was great all day and stayed really patient," Pendrith said. “I didn’t really have many good looks through the first hour I would say of golf and was able to stay patient and make a couple, made a couple longer ones, which was nice.”
NeSmith had a 64 in the morning before wind gusts topping 20 mph hit the course in the afternoon and early evening.
Seeking his first PGA Tour victory, NeSmith lost in a playoff two weeks ago at the ISCO Championship in Kentucky, his lone top-10 finish in 20 prior starts this season. He has missed 11 cuts.
“Patience is key out here whether it be to win golf tournaments, to make cuts, to try and keep your card to try and get in the top 30,” NeSmith said. “I think it pertains to each and every person out here. You never know when you’re going to get hot, you never know when good golf’s coming. Just kind of try and be patient, try and keep calmer heads and you never know what will happen.”
First-round leader Jacob Bridgeman had a 70 to drop three strokes back at 9 under with Andrew Putnam (66). Doug Ghim (64), Lanto Griffin (66), Alex Smalley (65) and Jhonattan Vegas (66) were 8 under.
“I felt like anything under par today was pretty good, especially in the afternoon,” said Bridgeman, one of the last players to tee off Friday. “The wind was blowing really hard in the beginning of the round, caught a little bit of a lull at the end, which was nice. But greens were kind of bumpy from all the traffic. … I stayed patient all day, didn’t really have a whole lot of great chances.”
The event is the second-to-last tournament before the FedEx Cup playoffs begin, with some players near the 70-player cutoff failing to advance to the weekend. Nick Dunlap (64th in the standings), Luke List (71st) and defending champion Lee Hodges (73rd) missed the cut.
Jacob Bridgeman walks on the 10th tee during the second round of the 3M Open golf tournament at the Tournament Players Club, Friday, July 26, 2024, in Blaine, Minn. (AP Photo/Charlie Neibergall)
Stewart Cink watches his tee shot on the 10th hole during the second round of the 3M Open golf tournament at the Tournament Players Club, Friday, July 26, 2024, in Blaine, Minn. (AP Photo/Charlie Neibergall)
Kurt Kitayama watches his tee shot on the second hole during the second round of the 3M Open golf tournament at the Tournament Players Club, Friday, July 26, 2024, in Blaine, Minn. (AP Photo/Charlie Neibergall)
Lanto Griffin watches his tee shot on the second hole during the second round of the 3M Open golf tournament at the Tournament Players Club, Friday, July 26, 2024, in Blaine, Minn. (AP Photo/Charlie Neibergall)
Andrew Putnam watches his tee shot on the second hole during the second round of the 3M Open golf tournament at the Tournament Players Club, Friday, July 26, 2024, in Blaine, Minn. (AP Photo/Charlie Neibergall)
Matt NeSmith walks off the 18th green after his putt during the second round of the 3M Open golf tournament at the Tournament Players Club, Friday, July 26, 2024, in Blaine, Minn. (AP Photo/Charlie Neibergall)
Matt NeSmith watches his tee shot on the second hole during the second round of the 3M Open golf tournament at the Tournament Players Club, Friday, July 26, 2024, in Blaine, Minn. (AP Photo/Charlie Neibergall)
Taylor Pendrith lines up his putt on the 18th green during the second round of the 3M Open golf tournament at the Tournament Players Club, Friday, July 26, 2024, in Blaine, Minn. (AP Photo/Charlie Neibergall)
Taylor Pendrith putts on the 18th green during the second round of the 3M Open golf tournament at the Tournament Players Club, Friday, July 26, 2024, in Blaine, Minn. (AP Photo/Charlie Neibergall)
