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The Latest: 2024 candidates tune their campaigns with less than 100 days to go

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The Latest: 2024 candidates tune their campaigns with less than 100 days to go
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The Latest: 2024 candidates tune their campaigns with less than 100 days to go

2024-08-01 09:52 Last Updated At:10:00

Donald Trump spoke Wednesday at a meeting of the National Association of Black Journalists, where his opponent in the presidential race, Vice President Kamala Harris, did not appear. The group said it was in discussions for her to address its members in September.

The Republican former president's appearance at the Chicago convention attracted protesters and came a day after Harris held a boisterous rally in Atlanta. The Trump campaign has said he plans an event Saturday at the same venue.

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Vice President Kamala Harris waves to supporters during her arrival in Houston on Wednesday, July 31, 2024. (AP Photo/Mat Otero)

Donald Trump spoke Wednesday at a meeting of the National Association of Black Journalists, where his opponent in the presidential race, Vice President Kamala Harris, did not appear. The group said it was in discussions for her to address its members in September.

Vice President Kamala Harris delivers remarks at a Sigma Gamma Rho Sorority gathering in Houston, Wednesday, July 31, 2024, in Houston. (AP Photo/Mat Otero)

Vice President Kamala Harris delivers remarks at a Sigma Gamma Rho Sorority gathering in Houston, Wednesday, July 31, 2024, in Houston. (AP Photo/Mat Otero)

Republican presidential candidate former President Donald Trump, left, moderated by from left, ABC's Rachel Scott, Semafor's Nadia Goba and FOX News' Harris Faulkner, speaks at the National Association of Black Journalists, NABJ, convention, Wednesday, July 31, 2024, in Chicago. (AP Photo/Charles Rex Arbogast)

Republican presidential candidate former President Donald Trump, left, moderated by from left, ABC's Rachel Scott, Semafor's Nadia Goba and FOX News' Harris Faulkner, speaks at the National Association of Black Journalists, NABJ, convention, Wednesday, July 31, 2024, in Chicago. (AP Photo/Charles Rex Arbogast)

Republican presidential candidate former President Donald Trump speaks at the National Association of Black Journalists, NABJ, convention, Wednesday, July 31, 2024, in Chicago. (AP Photo/Charles Rex Arbogast)

Republican presidential candidate former President Donald Trump speaks at the National Association of Black Journalists, NABJ, convention, Wednesday, July 31, 2024, in Chicago. (AP Photo/Charles Rex Arbogast)

A Secret Service agents stands post in front of the stage ahead of Republican presidential candidate former President Donald Trump speaking at the National Association of Black Journalists, NABJ, convention, Wednesday, July 31, 2024, in Chicago. (AP Photo/Charles Rex Arbogast)

A Secret Service agents stands post in front of the stage ahead of Republican presidential candidate former President Donald Trump speaking at the National Association of Black Journalists, NABJ, convention, Wednesday, July 31, 2024, in Chicago. (AP Photo/Charles Rex Arbogast)

FILE - Vice President Kamala Harris boards Air Force Two as she departs Westfield-Barnes Regional Airport in Westfield, Mass., July 27, 2024. With less than 100 days until Election Day, Harris faces unique challenges in pitching her policy ideas to Americans. (AP Photo/Stephanie Scarbrough, Pool, File)

FILE - Vice President Kamala Harris boards Air Force Two as she departs Westfield-Barnes Regional Airport in Westfield, Mass., July 27, 2024. With less than 100 days until Election Day, Harris faces unique challenges in pitching her policy ideas to Americans. (AP Photo/Stephanie Scarbrough, Pool, File)

Republican Arizona Senate candidate Kari Lake holds up a binder of Democratic Rep. Ruben Gallego's voting record, Lake's opponent in the upcoming general election, while speaking after being declared the primary winner Tuesday, July 30, 2024, in Phoenix. (AP Photo/Ross D. Franklin)

Republican Arizona Senate candidate Kari Lake holds up a binder of Democratic Rep. Ruben Gallego's voting record, Lake's opponent in the upcoming general election, while speaking after being declared the primary winner Tuesday, July 30, 2024, in Phoenix. (AP Photo/Ross D. Franklin)

FILE - Vice President Kamala Harris speaks during the American Federation of Teachers' 88th national convention, July 25, 2024, in Houston. Harris appears to have energized Democrats in the early days of her candidacy, according to a new poll from the AP-NORC Center for Public Affairs Research that was conducted after President Joe Biden withdrew from the race. About 8 in 10 Democrats say they would be very or somewhat satisfied if Harris became the Democratic nominee for president. (AP Photo/Tony Gutierrez, file)

FILE - Vice President Kamala Harris speaks during the American Federation of Teachers' 88th national convention, July 25, 2024, in Houston. Harris appears to have energized Democrats in the early days of her candidacy, according to a new poll from the AP-NORC Center for Public Affairs Research that was conducted after President Joe Biden withdrew from the race. About 8 in 10 Democrats say they would be very or somewhat satisfied if Harris became the Democratic nominee for president. (AP Photo/Tony Gutierrez, file)

FILE - Vice President Kamala Harris speaks at a campaign event, July 17, 2024, in Kalamazoo, Mich. Harris' views on important issues have shifted since she first ran for president four years ago. Back then, she took a variety of liberal positions on issues involving crime, energy and immigration. However, she generally charted a more moderate path after becoming vice president under President Joe Biden. (AP Photo/Carlos Osorio, File)

FILE - Vice President Kamala Harris speaks at a campaign event, July 17, 2024, in Kalamazoo, Mich. Harris' views on important issues have shifted since she first ran for president four years ago. Back then, she took a variety of liberal positions on issues involving crime, energy and immigration. However, she generally charted a more moderate path after becoming vice president under President Joe Biden. (AP Photo/Carlos Osorio, File)

FILE - Vice President Kamala Harris and second gentleman Doug Emhoff kiss during an event in the East Room of the White House in Washington, to light the menorah to celebrate Hanukkah, Dec. 1, 2021. Republican presidential candidate former President Donald Trump in an interview on Tuesday claimed Vice President Kamala Harris “doesn’t like Jewish people,” despite being married to a Jewish man and Trump seemed to agree with a radio host who called second gentleman Doug Emhoff “a crappy Jew.” (AP Photo/Susan Walsh, File)

FILE - Vice President Kamala Harris and second gentleman Doug Emhoff kiss during an event in the East Room of the White House in Washington, to light the menorah to celebrate Hanukkah, Dec. 1, 2021. Republican presidential candidate former President Donald Trump in an interview on Tuesday claimed Vice President Kamala Harris “doesn’t like Jewish people,” despite being married to a Jewish man and Trump seemed to agree with a radio host who called second gentleman Doug Emhoff “a crappy Jew.” (AP Photo/Susan Walsh, File)

Supporters cheer as they listen to Republican vice presidential candidate Sen. JD Vance, R-Ohio, during a campaign event in Reno, Nev., Tuesday, July 30, 2024. (AP Photo/Jae C. Hong)

Supporters cheer as they listen to Republican vice presidential candidate Sen. JD Vance, R-Ohio, during a campaign event in Reno, Nev., Tuesday, July 30, 2024. (AP Photo/Jae C. Hong)

The director of the Heritage Foundation’s Project 2025 vision for a complete overhaul of the federal government stepped down after blowback from Trump’s campaign, which has tried to disavow the program created by many of the former president’s allies and former aides.

Dueling ad campaigns by the presidential candidates portray Harris, a Democrat, as “fearless,” while an ad from Trump blasts the vice president for problems at the southern U.S. border.

Trump said in an interview Tuesday on radio station WABC that Harris “doesn’t like Jewish people” and appeared to agree with a host who called her Jewish husband, Doug Emhoff, “a crappy Jew.”

Follow the AP’s Election-2024 coverage at: https://apnews.com/hub/election-2024.

Here's the Latest:

Two famous women who live in Connecticut made surprise appearances during a virtual rally Wednesday night for Vice President Kamala Harris, billed as the launch of the “Connecticut Women for Harris” initiative. Both television producer and screenwriter Shonda Rhimes, who lives in Westport, and comedian and writer Samantha Bee, who lives in New Canaan, both spoke of the excitement they’re feeling and seeing surrounding her candidacy for president.

“What I’ve found is that there’s like this amazing swell of energy. A swell of energy and an excitement about everything. But the other thing that I feel I am getting from people is so much hope. People are feeling hopeful again for something that really matters. This is a story that I could not write and make up. There are twists in here that I could not have contemplated ... in any show I wrote,” said Rhimes, who said she’s known Harris for years.

Bee, who has interviewed Harris multiple times over the years, said she’s fired up about her candidacy, telling the women on the Zoom call: “I feel like my entire body is vibrating.” She added: “I’ve covered a lot of presidential campaigns, and this feels like a very special moment,” she said.

“I frankly have always thought that she would make an incredible president, and I know I’m not wrong. I love her laugh. Okay. I think it’s great. She laughs. That’s amazing. I love her vigor. I love her intelligence. I so admire her determination,” Bee said. “And truly, she is a best in class communicator on abortion and fighting for our bodily autonomy. Look, man, if this is the honeymoon period, I don’t want it to end. And really, why should it? It does not have to.”

Vice President Kamala Harris responded Wednesday to former President Donald Trump’s false suggestion that she misled voters about her race, saying “the American people deserve better.”

Speaking at the Sigma Gamma Rho Sorority Inc.’s 60th International Biennial Boule in Houston, Harris drew knowing chuckles from the audience as she mentioned Trump’s comments earlier in the day at the annual meeting of the National Association of Black Journalists.

“It was the same old show,” she said. “The divisiveness and the disrespect.”

“Our differences do not divide us, they are an essential source of our strength,” Harris added. “The American people deserve a leader who tells the truth, a leader who does not respond with hostility and anger when confronted with the facts.”

Vice President Kamala Harris is warning that after the Supreme Court found that presidents enjoy broad immunity from prosecution, former President Donald Trump will be emboldened like never before if he wins the White House again.

Speaking at a fundraiser in Houston, the likely Democratic presidential nominee said “this is not 2016 or 2020.”

“This month, the United States Supreme Court basically just told the former president, who has been convicted of fraud, that going forward, he will be immune for activity we know he is prepared to engage in if he gets back in the White House,” Harris told donors.” So think about that. At least before there was the threat that there might be consequences. Now there is implicit, some would say explicit, authority to know there will be no consequences.”

The remarks were Harris’ sharpest attack yet on Trump as she follows what had been a core component of President Joe Biden’s campaign message in branding Trump as a threat to American democracy.

Harris raised $2.5 million at the fundraiser, her campaign said.

White House press secretary Karine Jean-Pierre was asked during her briefing with reporters Wednesday about Donald Trump asking, about Kamala Harris, “Is she Indian or is she Black?” and making other derisive comments. She responded with disbelief, initially murmuring, “Wow.”

Jean-Pierre called what Trump said at a meeting of the National Association of Black Journalists in Chicago “repulsive” and said, "It’s insulting, and no one has any right to tell someone who they are how they identify.”

“That is no one’s right. It is someone’s own decision,” said Jean-Pierre, who said she was speaking “as a person of color, as a Black woman who is in this position, that is standing before you at this podium behind this lectern” in the White House briefing room.

“Only she can speak to her experience. Only she can speak to what it’s like,” Jean-Pierre said of Harris. “And I think it’s insulting for anybody — it doesn’t matter if it’s a former leader or former president, it is insulting.”

Robert F. Kennedy Jr.’s campaign announced ballot access in eight additional states: Alabama, Arkansas, Kansas, Massachusetts, Montana, North Dakota, Vermont and Virginia. This means, his campaign claims, he has enough signatures to get on the ballot in 42 states.

Trump repeatedly made false comparisons between protests that have taken place over the last several years, including the police brutality protests during COVID-19, and the attack on the U.S. Capitol on Jan. 6, 2021. But the events have been fundamentally different.

The insurrection at the Capitol was an intentional, direct attack on a hallowed democratic institution, to overturn a fair and free election. More than 1,400 people have been charged with federal crimes related to the Jan. 6 riot at the Capitol. Nearly 900 of them have pleaded guilty. Over 200 others have been convicted by judges or juries after trials in Washington, D.C. Only two Capitol riot defendants have been acquitted of all charges after trials.

Protests following the death of George Floyd by Minneapolis police were a coast-to-coast protest movement demanding an end to systemic racism that occasionally, but not frequently, turned violent.

Trump was asked during his appearance at the National Association of Black Journalists convention if he would pardon his supporters who assaulted more than 140 police officers while trying to breach the Capitol building while lawmakers were certifying Joe Biden’s 2020 presidential win. Trump deflected and began a long winded diatribe about the recent pro-Gaza protests near the Capitol last week where there were skirmishes with police and many demonstrators were arrested for publicly defacing property with anti-Semitic tropes and terrorist propaganda. There were no reported injuries of police or protesters at the recent protests, unlike the Capitol attack which resulted in one woman dead and several police officers who died after the fact due to related injuries and mental health trauma.

Donald Trump was questioned Wednesday at the conference of the National Association of Black Journalists about his vice presidential running mate, JD Vance, and Vance’s history of comments about the value of women or couples who don’t have children.

Asked why he chose Vance, Trump said it was because he represents a working-class upbringing.

“He’s a very smart guy without the benefit of having a family that has contact with a father that is well-connected,” the former president said. “I respect people for their success.”

Kadia Goba, of Semafor, received light applause when she noted that Trump was divorced and that Vance “may have opinions” about divorced people.

Trump received laughs and gasps when he said that Vance would also have opinions about childless people when he said “people like yourself” in response to Goba.

Asked if he, like Biden, would step down as president or presidential candidate if his health were to become an issue, Trump said Wednesday that he would and challenged Kamala Harris to a cognitive test while accusing her of failing her bar exam to become a lawyer.

“I would do it with her. I’ll say, you know what? She failed her law exam. She didn’t pass a law exam, so maybe she wouldn’t pass the cognitive test,” Trump said. While Harris reportedly failed her first attempt at the bar exam, she went on to pass the exam and later became elected as San Francisco’s district attorney and then as California’s attorney general.

A room full of journalists at the convention of the National Association of Black Journalists in Chicago stood largely stone-cold Wednesday as former President Donald Trump addressed them.

Some remarks drew interlaced boos, cheers and gasps as the conversation unfolded. Trump garnered rounds of laughs as he lambasted Rachel Scott and ABC News for their coverage of him and for the journalist’s questions about his record and rhetoric on race.

When Trump said he “wasn’t familiar” with the killing of Sonya Massey, many conventiongoers groaned. A white sheriff’s deputy shot and killed Massey inside her Illinois home this month after the Black woman called 911. A now-fired deputy has been charged with murder. President Joe Biden and Vice President Kamala Harris were among those to publicly mourn Massey.

Trump earlier in his remarks questioned the race of Vice President Kamala Harris, who is Black and Indian American.

Before he became a presidential candidate, Trump led efforts challenging the candidacy of former President Barack Obama by falsely asserting he was ineligible to run because he was born outside of the U.S. Birtherism, as it became known, was just the start of Trump’s history questioning the credentials and qualifications of Black politicians.

— The item above has been corrected to show that Massey was killed this month, not last month.

Donald Trump falsely questioned Kamala Harris’ race during an appearance Wednesday with the National Association of Black Journalists in Chicago that quickly turned hostile.

The Republican former president claimed that Harris, the first Black woman and Asian American to serve as vice president, had in the past promoted only her Indian heritage.

“I didn’t know she was Black until a number of years ago when she happened to turn Black, and now she wants to be known as Black. So I don’t know, is she Indian or is she Black?” Trump said.

Trump’s appearance immediately became heated as he sparred with interviewer Rachel Scott of ABC News, accusing her of giving him a “very rude introduction” with a tough first question about his past criticism of Black people and Black journalists.

“I think it’s disgraceful that I came here in good spirit. I love the Black population of this country; I’ve done so much for Black population of this country,” Trump said.

As an undergraduate, Harris attended Howard University, one of the nation’s most prominent historically Black institutions, where she also pledged the historically Black sorority Alpha Kappa Alpha. As a U.S. senator, Harris was a member of the Congressional Black Caucus.

Some protesters outside the venue played horns and musical instruments under the name Sousaphones Against Hate. “We played a whole bunch of protests going back to 2016 all the way through," said trombone player Dylan Rehm, 44. “So when we found out that he was going to be here today, we decided to do a version of an ode to Kendrick Lamar’s ‘Not Like Us,’ but we said ‘Trump’s not like us.'”

Second gentleman Doug Emhoff rallied New Hampshire Democrats on Wednesday, highlighting his wife’s commitment to restoring abortion rights and more.

“Once we get the presidency, get numbers in the Senate and the House, we can actually do something about this crisis,” he said. “You can see a world in which if Kamala Harris wins and we get the House and the Senate, we can make things happen in this country, not only on reproductive rights, but freedoms in general.”

Emhoff, who described as “surreal” the days since President Joe Biden ended his campaign and endorsed Vice President Kamala Harris, spoke to about 500 people in a union hall in Concord. As it has elsewhere, abortion has become a key campaign issue for Democrats in New Hampshire, where the procedure is legal up to 24 weeks of pregnancy but the Republican-led Legislature has rejected attempts to enshrine it as a right under the state constitution.

“We really have a stark choice between a life of freedom — fundamental rights, progress, moving forward, a place for all of us — and like I said, a hellscape,” Emhoff said.

Dozens of activists are protesting former President Donald Trump’s appearance in Chicago and chanting outside the downtown hotel where he will address the National Association of Black Journalists.

Their chants Wednesday included, “Donald Trump ain’t welcome here!” Several activists carried Palestinian flags and signs calling for “Peace, Justice, and Equity for All.”

Police presence was heavy outside the hotel, where a brass band also played at times. A few cars driving by the hotel along the busy Michigan Avenue corridor honked their horns.

A few people in Trump T-shirts, and at least one counterprotester who spoke against abortion, also stood outside the hotel.

Vice President Kamala Harris’ presidential campaign said ahead of Donald Trump’s appearance Wednesday at a meeting of the National Association of Black Journalists that he would lie about his record.

“Not only does Donald Trump have a history of demeaning NABJ members and honorees who remain pillars of the Black press, he also has a history of attacking the media and working against the vital role the press play in our democracy,” Jasmine Harris, the campaign’s director of Black media, said in a statement.

Harris, who is not related to the vice president, also said, “Black voters see Donald Trump’s lies and empty pandering for what they are — and they will hold him accountable at the polls this November.”

Kamala Harris is not scheduled to appear at the convention, but the NABJ said in a statement on the social platform X that it was in discussions with her campaign to have her appear virtually or in person for a conversation in September.

Trump posted on his social media network that he was told he could not do the event virtually.

“She declined, and I am getting ready to land in Chicago in order to be there,” Trump wrote. “Now I am told that she is doing the Event on ZOOM. WHAT’S GOING ON HERE?”

Chicago activists said that former President Donald Trump is “not welcome” in the nation’s third-largest city and that they’ll protest outside the hotel where he is expected to address the National Association of Black Journalists.

Activist groups, including the Chicago Alliance Against Racist and Political Repression, said they aren’t sure how many will attend their Wednesday protest. The demonstration is expected to start shortly before noon, when Trump will be interviewed by a panel of reporters.

Chicago Mayor Brandon Johnson is also attending the same convention hours after Trump. Johnson said in a post on the social media platform X that his administration’s values and practices “are in complete opposition to former President Donald Trump’s agenda.”

The first-term Democratic mayor says he wants to assure the public that city agencies and departments are “fully prepared to uphold safety during his scheduled visit.”

During his 2016 campaign, Trump canceled a rally in Chicago over safety concerns after protesters packed the arena where he was scheduled to speak.

Kamala Harris has put a charge in Wisconsin’s most powerful Democratic stronghold, Dane County, where enthusiasm and volunteer support for President Joe Biden had been slipping.

Voters in Madison, the county’s famously liberal heart, pointed to what they described in interviews as Harris’ more vocal attention to specific Democratic priorities, in addition to her younger age and livelier style, in helping to restore their enthusiasm in a place where the party must post overwhelming margins to carry the swing state.

Biden won 75% of the vote in the county, Wisconsin’s fastest-growing, in 2020, beating Trump by 181,000 votes there while carrying the state by fewer than 21,000.

With less than 100 days until Election Day, Vice President Kamala Harris faces challenges in pitching her policy ideas.

Republicans are trying to drag her down by reminding voters of her liberal positions from her unsuccessful 2020 primary campaign, as well as tag her with controversies from President Joe Biden's administration.

At the same time, Harris wants to harness Biden-era accomplishments while charting her own course to maximize her chances of defeating Republican Donald Trump. It’s a delicate dance that she’ll need to perform at high speeds in an unprecedented political situation.

Meanwhile, Trump’s invitation to address the National Association of Black Journalists has sparked an intense debate within the organization and a flurry of arguments online.

Trump’s acceptance of the invitation has led at least one high-profile group member to step down as a convention co-chair and others to argue their convention may become a platform for Trump to make false claims or be seen as winning NABJ’s endorsement.

News executives were worried in the first half of the year about consumers expressing relatively little interest in the upcoming election. That has now changed.

There’s evidence that interest has started to perk up following an extraordinary run of news. That includes the assassination attempt on former President Donald Trump, President Joe Biden’s decision not to seek reelection and the rapid ascension of Vice President Kamala Harris as the Democratic candidate.

Taboola says its measurement of news sites shows interest going up. Fox News was the most obvious beneficiary of the boost in attention, with July being its most-watched month since November 2020.

Vice President Kamala Harris waves to supporters during her arrival in Houston on Wednesday, July 31, 2024. (AP Photo/Mat Otero)

Vice President Kamala Harris waves to supporters during her arrival in Houston on Wednesday, July 31, 2024. (AP Photo/Mat Otero)

Vice President Kamala Harris delivers remarks at a Sigma Gamma Rho Sorority gathering in Houston, Wednesday, July 31, 2024, in Houston. (AP Photo/Mat Otero)

Vice President Kamala Harris delivers remarks at a Sigma Gamma Rho Sorority gathering in Houston, Wednesday, July 31, 2024, in Houston. (AP Photo/Mat Otero)

Republican presidential candidate former President Donald Trump, left, moderated by from left, ABC's Rachel Scott, Semafor's Nadia Goba and FOX News' Harris Faulkner, speaks at the National Association of Black Journalists, NABJ, convention, Wednesday, July 31, 2024, in Chicago. (AP Photo/Charles Rex Arbogast)

Republican presidential candidate former President Donald Trump, left, moderated by from left, ABC's Rachel Scott, Semafor's Nadia Goba and FOX News' Harris Faulkner, speaks at the National Association of Black Journalists, NABJ, convention, Wednesday, July 31, 2024, in Chicago. (AP Photo/Charles Rex Arbogast)

Republican presidential candidate former President Donald Trump speaks at the National Association of Black Journalists, NABJ, convention, Wednesday, July 31, 2024, in Chicago. (AP Photo/Charles Rex Arbogast)

Republican presidential candidate former President Donald Trump speaks at the National Association of Black Journalists, NABJ, convention, Wednesday, July 31, 2024, in Chicago. (AP Photo/Charles Rex Arbogast)

A Secret Service agents stands post in front of the stage ahead of Republican presidential candidate former President Donald Trump speaking at the National Association of Black Journalists, NABJ, convention, Wednesday, July 31, 2024, in Chicago. (AP Photo/Charles Rex Arbogast)

A Secret Service agents stands post in front of the stage ahead of Republican presidential candidate former President Donald Trump speaking at the National Association of Black Journalists, NABJ, convention, Wednesday, July 31, 2024, in Chicago. (AP Photo/Charles Rex Arbogast)

FILE - Vice President Kamala Harris boards Air Force Two as she departs Westfield-Barnes Regional Airport in Westfield, Mass., July 27, 2024. With less than 100 days until Election Day, Harris faces unique challenges in pitching her policy ideas to Americans. (AP Photo/Stephanie Scarbrough, Pool, File)

FILE - Vice President Kamala Harris boards Air Force Two as she departs Westfield-Barnes Regional Airport in Westfield, Mass., July 27, 2024. With less than 100 days until Election Day, Harris faces unique challenges in pitching her policy ideas to Americans. (AP Photo/Stephanie Scarbrough, Pool, File)

Republican Arizona Senate candidate Kari Lake holds up a binder of Democratic Rep. Ruben Gallego's voting record, Lake's opponent in the upcoming general election, while speaking after being declared the primary winner Tuesday, July 30, 2024, in Phoenix. (AP Photo/Ross D. Franklin)

Republican Arizona Senate candidate Kari Lake holds up a binder of Democratic Rep. Ruben Gallego's voting record, Lake's opponent in the upcoming general election, while speaking after being declared the primary winner Tuesday, July 30, 2024, in Phoenix. (AP Photo/Ross D. Franklin)

FILE - Vice President Kamala Harris speaks during the American Federation of Teachers' 88th national convention, July 25, 2024, in Houston. Harris appears to have energized Democrats in the early days of her candidacy, according to a new poll from the AP-NORC Center for Public Affairs Research that was conducted after President Joe Biden withdrew from the race. About 8 in 10 Democrats say they would be very or somewhat satisfied if Harris became the Democratic nominee for president. (AP Photo/Tony Gutierrez, file)

FILE - Vice President Kamala Harris speaks during the American Federation of Teachers' 88th national convention, July 25, 2024, in Houston. Harris appears to have energized Democrats in the early days of her candidacy, according to a new poll from the AP-NORC Center for Public Affairs Research that was conducted after President Joe Biden withdrew from the race. About 8 in 10 Democrats say they would be very or somewhat satisfied if Harris became the Democratic nominee for president. (AP Photo/Tony Gutierrez, file)

FILE - Vice President Kamala Harris speaks at a campaign event, July 17, 2024, in Kalamazoo, Mich. Harris' views on important issues have shifted since she first ran for president four years ago. Back then, she took a variety of liberal positions on issues involving crime, energy and immigration. However, she generally charted a more moderate path after becoming vice president under President Joe Biden. (AP Photo/Carlos Osorio, File)

FILE - Vice President Kamala Harris speaks at a campaign event, July 17, 2024, in Kalamazoo, Mich. Harris' views on important issues have shifted since she first ran for president four years ago. Back then, she took a variety of liberal positions on issues involving crime, energy and immigration. However, she generally charted a more moderate path after becoming vice president under President Joe Biden. (AP Photo/Carlos Osorio, File)

FILE - Vice President Kamala Harris and second gentleman Doug Emhoff kiss during an event in the East Room of the White House in Washington, to light the menorah to celebrate Hanukkah, Dec. 1, 2021. Republican presidential candidate former President Donald Trump in an interview on Tuesday claimed Vice President Kamala Harris “doesn’t like Jewish people,” despite being married to a Jewish man and Trump seemed to agree with a radio host who called second gentleman Doug Emhoff “a crappy Jew.” (AP Photo/Susan Walsh, File)

FILE - Vice President Kamala Harris and second gentleman Doug Emhoff kiss during an event in the East Room of the White House in Washington, to light the menorah to celebrate Hanukkah, Dec. 1, 2021. Republican presidential candidate former President Donald Trump in an interview on Tuesday claimed Vice President Kamala Harris “doesn’t like Jewish people,” despite being married to a Jewish man and Trump seemed to agree with a radio host who called second gentleman Doug Emhoff “a crappy Jew.” (AP Photo/Susan Walsh, File)

Supporters cheer as they listen to Republican vice presidential candidate Sen. JD Vance, R-Ohio, during a campaign event in Reno, Nev., Tuesday, July 30, 2024. (AP Photo/Jae C. Hong)

Supporters cheer as they listen to Republican vice presidential candidate Sen. JD Vance, R-Ohio, during a campaign event in Reno, Nev., Tuesday, July 30, 2024. (AP Photo/Jae C. Hong)

Next Article

Nobel Prize in medicine honors American duo for their discovery of microRNA

2024-10-07 19:18 Last Updated At:19:22

STOCKHOLM (AP) — The Nobel Prize in physiology or medicine was awarded Monday to Americans Victor Ambros and Gary Ruvkun for their discovery of microRNA, tiny pieces of genetic material that alter how genes work at the cellular level and could lead to new ways of treating cancer.

The Nobel Assembly at the Karolinska Institute, which awarded the prize, said the duo's discovery is “proving to be fundamentally important for how organisms develop and function."

“Their groundbreaking discovery revealed a completely new principle of gene regulation that turned out to be essential for multicellular organisms, including humans,” the assembly said in a statement explaining the importance of their work.

Ambros performed the research that led to his prize at Harvard University. He is currently a professor of natural science at the University of Massachusetts Medical School. Ruvkun’s research was performed at Massachusetts General Hospital and the Harvard Medical School, where he’s a professor of genetics, said Thomas Perlmann, Secretary-General of the Nobel Committee.

Perlmann said he spoke to Ruvkun by phone shortly before the announcement.

“It took a long time before he came to the phone and sounded very tired, but he quite rapidly was quite excited and happy, when he understood what it was all about,” Perlmann said.

Ambros and Ruvkun, the assembly explained, were initially interested in genes that control the timing of different genetic developments, ensuring that cell types develop at the right time.

To do that, they studied two mutant strains of worms commonly used as research models in science. The two scientists set out to identify the mutated genes responsible in these worms and what their role was. The mechanism they ultimately identified — the regulation of genes by microRNA — has allowed organisms to evolve for hundreds of millions of years.

The Nobel committee said Ambros and Ruvkun’s discovery ultimately “revealed a new dimension to gene regulation, essential for all complex life forms.”

MicroRNA have opened up scientists’ approaches to treating diseases like cancer by helping to regulate how genes work at the cellular level, according to Dr. Claire Fletcher, a lecturer in molecular oncology at Imperial College London.

Fletcher said microRNA provide genetic instructions to tell cells to make new proteins and that there were two main areas where microRNA could be helpful: in developing drugs to treat diseases and in serving as biomarkers.

“MicroRNA alters how genes in the cell work,” said Fletcher, who is an outside expert not associated with the Nobel prize.

“If we take the example of cancer, we’ll have a particular gene working overtime, it might be mutated and working in overdrive,” she said. “We can take a microRNA that we know alters the activity of that gene and we can deliver that particular microRNA to cancer cells to stop that mutated gene from having its effect.”

Last year, the Nobel Prize in Physiology or Medicine went to Hungarian-American Katalin Karikó and American Drew Weissman for discoveries that enabled the creation of mRNA vaccines against COVID-19 that were critical in slowing the pandemic.

The prize carries a cash award of 11 million Swedish kronor ($1 million) from a bequest left by the prize’s creator, Swedish inventor Alfred Nobel.

The announcement launched this year’s Nobel prizes award season.

Nobel announcements continue with the physics prize on Tuesday, chemistry on Wednesday and literature on Thursday. The Nobel Peace Prize will be announced Friday and the Nobel Memorial Prize in Economic Sciences on Oct. 14.

The laureates are invited to receive their awards at ceremonies on Dec. 10, the anniversary of Nobel’s death.

Fletcher said there are clinical trials ongoing to see how microRNA approaches might help treat skin cancer, but that there aren’t yet any drug treatments approved by drug regulators. She expected that might happen in the next five to 10 years.

She said microRNA represent another way of being able to control the behaviour of genes to treat and track various diseases.

“The majority of therapies we have at the moment are targeting proteins in cells,” she said. “If we can intervene at the microRNA level, it opens up a whole new way of us developing medicines and us controlling the activity of genes whose levels might be altered in diseases.”

Corder reported from The Hague, Netherlands, Cheng reported from London.

This picture released by UMass shows Victor Ambros, PhD, the Silverman Chair in Natural Sciences and professor of molecular medicine at UMass Chan in Worcester, Mass., Feb. 7, 2024. (Faith Ninivaggi via AP)

This picture released by UMass shows Victor Ambros, PhD, the Silverman Chair in Natural Sciences and professor of molecular medicine at UMass Chan in Worcester, Mass., Feb. 7, 2024. (Faith Ninivaggi via AP)

This picture released by UMass shows Victor Ambros, PhD, the Silverman Chair in Natural Sciences and professor of molecular medicine at UMass Chan in Worcester, Mass., Feb. 7, 2024. (Faith Ninivaggi via AP)

This picture released by UMass shows Victor Ambros, PhD, the Silverman Chair in Natural Sciences and professor of molecular medicine at UMass Chan in Worcester, Mass., Feb. 7, 2024. (Faith Ninivaggi via AP)

Gary Ruvkun, American molecular biologist, 2024 Nobel Prize winner in physiology or medicine, speaks with a reporter, Monday, Oct. 7, 2024, at his home, in Newton, Mass. (AP Photo/Steven Senne)

Gary Ruvkun, American molecular biologist, 2024 Nobel Prize winner in physiology or medicine, speaks with a reporter, Monday, Oct. 7, 2024, at his home, in Newton, Mass. (AP Photo/Steven Senne)

Gary Ruvkun, American molecular biologist, 2024 Nobel Prize winner in physiology or medicine, speaks with a reporter, Monday, Oct. 7, 2024, at his home, in Newton, Mass. (AP Photo/Steven Senne)

Gary Ruvkun, American molecular biologist, 2024 Nobel Prize winner in physiology or medicine, speaks with a reporter, Monday, Oct. 7, 2024, at his home, in Newton, Mass. (AP Photo/Steven Senne)

This combo of pictures released by Mass General and UMass show American molecular biologist Gary Ruvkun, left, and UMass Chair in Natural Sciences and professor of molecular medicine, Victor Ambros. (Joshua Touster and UMass via AP)

This combo of pictures released by Mass General and UMass show American molecular biologist Gary Ruvkun, left, and UMass Chair in Natural Sciences and professor of molecular medicine, Victor Ambros. (Joshua Touster and UMass via AP)

This undated picture released by Mass General shows American molecular biologist Gary Ruvkun. (Joshua Touster via AP)

This undated picture released by Mass General shows American molecular biologist Gary Ruvkun. (Joshua Touster via AP)

This undated picture released by UMass shows Victor Ambros, PhD, the Silverman Chair in Natural Sciences and professor of molecular medicine. (UMass via AP)

This undated picture released by UMass shows Victor Ambros, PhD, the Silverman Chair in Natural Sciences and professor of molecular medicine. (UMass via AP)

Olle Kämpe, right, professor of clinical endocrinology, explains the work of this year's Nobel Prize in Physiology or Medicine laureates Americans Victor Ambros, and Gary Ruvkun during a press conference at the Karolinska Institute in Stockholm, Sweden, on Monday, Oct. 7, 2024. (Christine Olsson/TT News Agency via AP)

Olle Kämpe, right, professor of clinical endocrinology, explains the work of this year's Nobel Prize in Physiology or Medicine laureates Americans Victor Ambros, and Gary Ruvkun during a press conference at the Karolinska Institute in Stockholm, Sweden, on Monday, Oct. 7, 2024. (Christine Olsson/TT News Agency via AP)

Olle Kämpe, right, professor of clinical endocrinology, explains the work of this year's Nobel Prize in Physiology or Medicine laureates Americans Victor Ambros, and Gary Ruvkun, pictured on the screen, during a press conference at the Karolinska Institute in Stockholm, Sweden, on Monday, Oct. 7, 2024. (Christine Olsson/TT News Agency via AP)

Olle Kämpe, right, professor of clinical endocrinology, explains the work of this year's Nobel Prize in Physiology or Medicine laureates Americans Victor Ambros, and Gary Ruvkun, pictured on the screen, during a press conference at the Karolinska Institute in Stockholm, Sweden, on Monday, Oct. 7, 2024. (Christine Olsson/TT News Agency via AP)

Americans Victor Ambros, left, and Gary Ruvkun, are seen on a screen after being awarded this year's Nobel Prize in Physiology or Medicine during a press conference to announce the winners at the Karolinska Institute in Stockholm, Sweden, on Monday, Oct. 7, 2024. (Christine Olsson/TT News Agency via AP)

Americans Victor Ambros, left, and Gary Ruvkun, are seen on a screen after being awarded this year's Nobel Prize in Physiology or Medicine during a press conference to announce the winners at the Karolinska Institute in Stockholm, Sweden, on Monday, Oct. 7, 2024. (Christine Olsson/TT News Agency via AP)

Nobel Committee chairman Thomas Perlmann, right, announces Americans Victor Ambros, left, and Gary Ruvkun, seen on a screen being awarded this year's Nobel Prize in Physiology or Medicine, during a press conference at the Karolinska Institute in Stockholm, Sweden, on Monday, Oct. 7, 2024. (Christine Olsson/TT News Agency via AP)

Nobel Committee chairman Thomas Perlmann, right, announces Americans Victor Ambros, left, and Gary Ruvkun, seen on a screen being awarded this year's Nobel Prize in Physiology or Medicine, during a press conference at the Karolinska Institute in Stockholm, Sweden, on Monday, Oct. 7, 2024. (Christine Olsson/TT News Agency via AP)

FILE - A close-up view of a Nobel Prize medal at the National Institutes of Health (NIH) in Bethesda, Md., Tuesday, Dec. 8, 2020. (AP Photo/Jacquelyn Martin, File)

FILE - A close-up view of a Nobel Prize medal at the National Institutes of Health (NIH) in Bethesda, Md., Tuesday, Dec. 8, 2020. (AP Photo/Jacquelyn Martin, File)

FILE - A bust of Alfred Nobel on display following a press conference at the Karolinska Institute in Stockholm, Sweden, on Monday, Oct. 3, 2022. (Henrik Montgomery/TT News Agency via AP, File)

FILE - A bust of Alfred Nobel on display following a press conference at the Karolinska Institute in Stockholm, Sweden, on Monday, Oct. 3, 2022. (Henrik Montgomery/TT News Agency via AP, File)

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