SEOUL, South Korea, Sept. 10, 2024 /PRNewswire/ -- Lunit (KRX:328130.KQ), a leading provider of AI-powered solutions for cancer diagnostics and therapeutics, today announced the presentation of a significant study at the European Society for Medical Oncology (ESMO) Congress 2024 in Barcelona, Spain, from September 13-17.
While Nivolumab plus chemotherapy has recently been approved as a standard first-line treatment for advanced gastric cancer (AGC), its efficacy varies among patients. This variability underscores the critical need for reliable biomarkers to predict treatment response. Lunit's study addresses this pressing need, potentially offering a new tool to optimize patient care and treatment decisions.
Conducted in collaboration with leading Korean medical institutions, the research showcases the potential of Lunit's AI-powered histopathology analyzer, Lunit SCOPE IO®, in predicting treatment response and guiding treatment decisions for AGC via assessment of immune phenotype.
The study analyzed H&E images from 585 AGC patients, with Lunit SCOPE IO® classifying tumors into two immune phenotypes—inflamed (IIP) and non-inflamed—based on the presence and distribution of tumor-infiltrating lymphocytes (TILs) from hematoxylin and eosin (H&E) slides that are readily available from a standard clinical workup. This classification provided valuable insights into the tumor microenvironment and helped predict treatment response, particularly in cases where traditional biomarkers like PD-L1 may not provide a complete picture.
Key findings include:
1. Patients treated with Nivolumab+Chemotherapy showed significantly longer median progression-free survival (mPFS) compared to Chemotherapy alone (8.2 vs. 5.9 months).
2. The inflamed immune phenotype group, classified by Lunit SCOPE IO®, was associated with more pronounced PFS benefits from Nivolumab+Chemotherapy:
3. The predictive value of IIP was consistent across different PD-L1 expression levels.
4. Multivariate analysis confirmed IIP as an independent factor for PFS in patients treated with Nivolumab+Chemotherapy.
"By demonstrating that our AI-powered immune phenotype analysis can predict treatment response independently of PD-L1 status, we're opening new possibilities for tailoring treatments in AGC," said Brandon Suh, CEO of Lunit. "This is particularly significant because gastric cancer continues to be a leading cause of cancer-related deaths globally, representing 7.7% of all cancer cases. Our AI technology has the potential to enhance the precision of treatment decisions, potentially leading to more effective therapies and better quality of life for patients with AGC."
Please visit Lunit's poster session at 1411P to discover more about our findings and the innovative capabilities of Lunit SCOPE IO®.
Poster presentation featuring Lunit SCOPE IO at ESMO Congress 2024:
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About Lunit
Founded in 2013, Lunit (KRX:328130.KQ) is a medical AI company on a mission to conquer cancer. We harness AI-powered medical image analytics and AI biomarkers to ensure accurate diagnosis and optimal treatment for each cancer patient. Our FDA-cleared Lunit INSIGHT suite for cancer screening serves over 3,500 hospitals and medical institutions across 50+ countries.
Our clinical studies have been published in top journals, including the Journal of Clinical Oncology and the Lancet Digital Health, and presented at global conferences such as the ASCO and RSNA. In 2024, Lunit acquired Volpara Health Technologies, setting the stage for unparalleled synergy and accuracy, particularly in breast health and screening technologies. Headquartered in Seoul, South Korea, with a network of offices worldwide, Lunit leads the global fight against cancer. Discover more at lunit.io.
** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **
Lunit to Present AI-Analyzed Immune Phenotype Study as Immunotherapy Response Predictor for Advanced Gastric Cancer at ESMO Congress 2024
Borneo Pickleball International Tournament 2024 (BPIT)
Venue: Pikabol - Malaysia's Pickleball Powerhouse
Date: 14th October 2024
KUCHING, Malaysia, Oct. 14, 2024 /PRNewswire/ -- After four days of intense competition and exhilarating matches, the Borneo Pickleball International Tournament 2024 (BPIT) came to a thrilling conclusion today at Pikabol - Malaysia's Pickleball Powerhouse. The tournament, which saw talented players from across the region, celebrated the spirit of sportsmanship, teamwork, and skill as the finest pickleball players competed for top honors.
The tournament, which ran from October 10th to 13th, brought together over 500 athletes competing in both team and individual categories, including the Team Event, Mixed Doubles Veteran, and Novice Double. Spectators were treated to a display of athletic excellence as seasoned professionals and rising stars showcased their talents in every match.
Winners Take the Stage
The prestigious tournament awarded a total prize pool of RM20,650, alongside trophies, medals, and exclusive prizes generously sponsored by Skechers and Starbucks. Champions and runner ups in the team event category received the coveted BPIT 2024 Trophies, symbolizing their triumph and dedication to the sport.
In the Team Event, Paragon SG emerged as the Champions, with Paragon Perfecto securing the Runner-Up spot after a hard-fought finale. The ESM Voltage Vipers Pickleball claimed 3rd place, while Dayak Daily Berami proudly took 4th. In the Mixed Doubles Veteran category, Hari Mohan and Varsha Majmudar proved their dominance, taking the Championship title, followed closely by Moon Tan and Chong Siew Tan as Runners-Up. In 3rd place were Jeffery Kuok and Monaliza Ibrahim, while Lydia Wong and Andrew Soo took home the 4th spot.
The Novice Doubles category saw a stunning performance from Izzudin Mohd Razali and Afiq Aziz who clinched the top spot, while Shaifful bin Sapian and Khairil Azrie bin Jamat battled their way to 2nd place. The competition was fierce, with Sean Aziz Abdullah and Faustino Rinaldon Mundaw along with Nik Nasron Bin Halik and Muqri Othman finishing in 3rd and 4th place, respectively. The event was a thrilling success, leaving spectators in awe and setting a high standard for future tournaments.
The winners were honored in a grand awards ceremony, where YB Datuk Snowdan Lawan presented the medals on stage. YB Datuk Snowdan Lawan commended the players for their remarkable performance and highlighted the spirit of teamwork and perseverance shown throughout the tournament. The event was a thrilling success, leaving spectators in awe and setting a high standard for future tournaments.
A Special Thanks to Our Sponsors & Endorsers
BPIT 2024 was made possible thanks to the unwavering support of our sponsors, the Malaysia Convention and Exhibition Bureau, Sarawak Energy Berhad, WTK, Starbucks, PIKABOL, DHI, Odysportsz, and Pickleball Global for their invaluable support and ongoing commitment to the development of pickleball in the region. Their involvement has helped elevate the tournament, making it a standout event in Malaysia's sporting calendar.
The tournament proudly received endorsements from both the Malaysia Pickleball Association and the Sarawak Pickleball Association. It also garnered strong backing from the Ministry of Youth, Sports, and Entrepreneur Development Sarawak and the Ministry of Tourism, Creative Industry, and Performing Arts Sarawak.
A Celebration of Community and Sport
Speaking at the closing ceremony, Mr. Ruslan Bujang, Chairman of BPIT 2024 expressed gratitude to the tournament's key partners for their unwavering support. He extended special thanks to the BPIT2024's Exclusive Strategic Advisor Business Events Sarawak and it's partners - Malaysia Airlines, CPH Travels, Sarawak Tourism Board, and The Hemisphere—for their exceptional contributions in providing services to participants and fostering the growth of sports tourism in Sarawak.
With the 2024 edition successfully concluded, the excitement for next BPIT is already building. As pickleball continues to grow in popularity across Malaysia and beyond, the BPIT remains a key platform for players to demonstrate their prowess and for fans to experience the very best of the sport.
** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **
A Triumphant Conclusion to the Borneo Pickleball International Tournament 2024
