BARCELONA, Spain, Sept. 20, 2024 /PRNewswire/ -- The highly anticipated 2024 European Society for Medical Oncology (ESMO) Annual Congress has taken place from September 13 to 17 in Barcelona, Spain. As one of the most influential annual gatherings in oncology, this congress brings together leading cancer experts and researchers from around the globe, showcasing the latest advancements in the field and providing high-quality educational and networking opportunities for oncology professionals.
Biosyngen, an innovative biotechnology company specializing in immune cell therapies, has showcased its groundbreaking technology on gene-modified, functionally enhanced tumor-infiltrating lymphocytes (TILs) derived from liver cancer biopsy samples.
BioSyngen has secured ten clinical trial approvals in China and the U.S. for its innovative fourth-generation oncology therapies. Currently, our leading pipeline product, BRG01, is in the pivotal Phase II clinical trial stage for solid tumors. Additionally, the first patients have been enrolled in the Phase I trials for our other groundbreaking therapies, BST02 and BRL03, with completion of Phase I trials anticipated later this year.
Abstract Title
Pre-clinical Development of Genetically Modified Tumor-infiltrating Lymphocytes using Biopsy Samples from Liver Cancer Patients
Abstract No.
1034P
Tumor-infiltrating lymphocytes (TILs) are heterogeneous lymphocyte populations within the tumor microenvironment that contains T cells capable of recognizing tumor- or virus-associated antigens. In February of this year, the FDA approved the first TIL-based therapy used with IL-2 for advanced metastatic/recurrent melanoma. However, due to the variability in T cell infiltration between hot and cold tumors, differential abundance of antigen-specific T cells with robust immune response functionality, and the dependence of TIL anti-tumor efficacy on concomitant use of high-dose IL-2 combination therapy, the therapeutic applications of non-edited TILs are quite limited outside of melanoma.
To address these challenges, Biosyngen has developed a proprietary platform for expanding TILs from biopsy samples, achieving production of 1011 cells within four weeks. Additionally, the company has established a stable gene modification platform that reprograms TIL metabolism, enhances TIL activity and sustained antitumor efficacy by expressing membrane anchor proteins. Anti-tumor efficacy has significantly enhanced (without IL-2 co-injection) and no obvious toxicity observed.
Biosyngen houses best-in-class proprietary TIL platform aiming to expand the clinical applications of TIL technology with following features:
** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **
Biosyngen Best-in-Class Next-Generation Tumor-Infiltrating Lymphocyte (TIL) Technology Debuts on ESMO 2024 Annual Meeting
Biosyngen Best-in-Class Next-Generation Tumor-Infiltrating Lymphocyte (TIL) Technology Debuts on ESMO 2024 Annual Meeting
One of Singapore's most popular IT festivals to host nationwide tournaments and influencer face-offs on top of exclusive IT deals and latest gadgets showcase
SINGAPORE, Nov. 8, 2024 /PRNewswire/ -- Organiser for popular IT fairs COMEX, ITSHOW and Consumer Electronics Exhibition (CEE), Constellar will conclude its annual consumer electronics and technology series on a high note with The Tech Show (TTS) 2024, to be held at Singapore EXPO Hall 6B from 14 to 17 November 2024. This year's edition aims to become the premier destination for all things gaming, including latest gadgets that enhance the gaming experience and trending games that appeal to gamers of all ages and levels.
For the first time, TTS 2024 is partnering with the Singapore Cybersports & Online Gaming Association (SCOGA) to host Campus Legends Secondary School, Singapore's premier collegiate esports tournament which gives student gamers the ultimate stage to compete nationally by representing their schools. Together with SCOGA, Tournament Sponsor Logitech and Official Gaming PC, Predator. TTS 2024 will also host the inaugural Stellar Esports Cup powered by Constellar. This community tournament aims to bring together players of every age and skill level, uniting the community through the thrill of competition and the spirit of teamwork. Over 60 teams consisting players of all levels will compete and showcase their skills in Valorant and Mobile Legends Bang Bang, while vying with one another for a staggering prize pool of up to $15,000 in cash and products.
"By participating in The Tech Show, SCOGA aims to elevate the profile of esports in Singapore and showcase the exceptional talents of our young athletes from Campus Legends Secondary School," said Mr Dennis Ooi, President, SCOGA. "We are excited to collaborate with Constellar and partners to raise awareness about the positive impact of esports on youth development. Through this partnership, we hope to inspire the next generation of gamers and create a thriving esports ecosystem in Singapore," he added.
"The Tech Show seeks to set the stage for larger, more impactful gaming events to be hosted in future editions. By bringing gamers and tech enthusiasts together, we aim to foster a close-knit, multi-generational gaming community and create a safe, dynamic and engaging space for youth and avid gamers of all ages in Singapore. We aim to continuously engage the young in an offline retail environment through experiences and forging memories," said Mr Paul Lee, Chief Executive (Markets), Constellar.
TTS 2024 promises an electrifying atmosphere, with influencers @HeyThomask, @Stylobin, @crazneax and @Jaxine teaming up in a Creators' Showdown against their fans. Visitors will be able to watch the live event on 16th November (Saturday), from 3pm onwards. Fans of Paper Rex, one of the world's best Valorant teams, can also look forward to exclusive meet-and-greets with team members @Jingggxd and @spicyuuu on Saturday from 3-5pm.
"While our Singapore team has enjoyed tremendous success on the international stage in Valorant, many Singaporeans are still unaware of us and we cannot wait to introduce ourselves to new fans," said Mr Nikhil Hathiramani, Co-Founder & CEO of IMPLS Entertainment, the agency representing Paper Rex. "Paper Rex has always been proud to represent Singapore on the global esports stage. While Singapore's gaming community is smaller, it is vibrant, passionate, and rapidly growing, with an incredible mix of talent and enthusiasm. We are excited to support the local gaming community and inspire aspiring gamers," he added.
Other Key Highlights
Don't Miss Out. Mark your calendars and join us at Singapore Expo Hall 6B from 14-17 November. Concurrent events happening in Singapore EXPO during the same weekend include the APAC F&B Expo, Baby Land and Mega Beauty Festival.
For latest information on the gaming tournaments, deals and updates, visit our website and follow us on Facebook, Instagram and TikTok. Sign up here to receive the digital brochure with the best highlights and deals dropping on 13 November 2024.
About Constellar
Constellar is Asia's preferred partner for convening businesses, curating ideas and creating opportunities for sustainable business growth and global impact. Based in Singapore with a regional footprint in China and Malaysia, we curate and develop influential trade and consumer events for key industries, connecting global marketplaces in sectors such as fintech, industrial transformation and ESG. We also manage the Singapore EXPO, Singapore's largest purpose-built venue for Meetings, Incentives, Conventions and Exhibitions (MICE). Our vision is to be a global leader made in Asia, activating impactful networks to enable cross-industry collaboration and innovation through our holistic portfolio of intellectual properties in the MICE industry. Visit constellar.co for more information.
ANNEX A: Exhibitors' Highlights (Non-Exhaustive)
Exhibitor
Event Highlight(s)
Dreamcore
Dreamcore will be launching the new Ghost Pro Gaming PC featuring latest components, and offering up to $800 off gaming PCs and tons of freebies.
Hinomi
Hinomi is thrilled to announce its exclusive Tech Show offers, featuring up to 60% off on a wide range of ergonomic solutions. From the unique foldable H1 Pro ergonomic chair, perfect for flexible living spaces, to the gamer-friendly X1 chair with advanced ergonomic support, Hinomi has everyone covered. In an exciting collaboration with Tefal, shoppers will have a chance to spin and win amazing prizes, such as the Tefal IXEO+ Garment Steamer(worth $459) and Frutelia Plus Juicer (worth $89.9).
Hydroflux
Discover Hydroflux's Range of Water Purifiers:
• WISH Water Purifier: Hydroflux's flagship model, popular among families for its sleek vintage design, blending functionality with timeless style.
• NAMI Water Purifier: A bestseller known for its simple, compact design, making it a favorite for households looking for efficient, space-saving solutions.
• IGLOO Ice-Making Water Purifier: A unique dual-function purifier that dispenses purified ice on one side and water on the other, perfect for those seeking convenience and versatility.
Enjoy exclusive discounts up to $900 off, plus complimentary gifts with every purchase.
Logitech
Logitech is the Tournament Sponsor for the Gaming Arena, supporting The Tech Show 2024 with their innovative products from gaming headsets, keyboard and mouse on stage and off stage. Consumers can enjoy a range of promotions at their sales booth at the show.
OSIM
OSIM will be showcasing its UThrone V Gaming Massage Chair, the only gaming chair with massage, designed for gamers.
Prism+
Prism+ will be displaying its top-of-the-line Mini LED series with Google TV, which promises the best viewing experience.
SecretLab
Visitors can try out the latest gaming chairs from SecretLab, such as the following:
• Secretlab VALORANT Collection
• Secretlab TITAN Evo NanoGen™ Edition – This one's a game-changer, offering the perfect balance of comfort and ergonomics that everyone will want to experience.
• Secretlab Ergonomic Recliner Add-On
• Secretlab TITAN Evo Paper Rex Edition
• Secretlab TITAN Evo Final Fantasy XIV Edition
• Secretlab for Automobili Lamborghini Deluxe Edition – This edition will definitely draw attention; no other brand can rival the prestige of our collaborations.
TTRacing
Visitors can experience the following gaming chairs and smart desks from TTRacing:
• TTRacing Maxx Air Threads Fabric Gaming Chair - Luffy Edition
• TT AIRFLEX Ergochair
• TTRacing Titus Smart Desk
ULTI
ULTI will be showcasing its APEX+ Ascent Ergonomic Chairs which offer unmatched comfort and convenience, engineered for seamless transitions between relaxation, play and productivity.
** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **
Gaming & Esports Takes Center Stage at The Tech Show 2024