Bruker Announces 1.2 GHz NMR Spectrometer at Swiss High-field NMR Facility

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Bruker Announces 1.2 GHz NMR Spectrometer at Swiss High-field NMR Facility

2024-12-20 19:00 Last Updated At：19:10

ZÜRICH--(BUSINESS WIRE)--Dec 20, 2024--

Bruker announces the acceptance of a 1.2 GHz Ascend™ Nuclear Magnetic Resonance (NMR) spectrometer at the Swiss High-field NMR Facility, operated jointly by the University of Basel, ETH Zürich, and the University of Zürich. This state-of-the-art instrument will significantly enhance the research capabilities of several user groups, enabling advanced studies in structural biology and macromolecular analysis. The instrument, located at the University of Zürich, is the second 1.2 GHz NMR in Switzerland, with the first at ETH used for developing solid-state NMR techniques, and studying materials and biological systems.

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The Swiss High-field NMR Facility has locations at Biozentrum Basel and at University of Zürich. The new 1.2 GHz NMR complements the existing 800 MHz NMR in Basel and other high-field NMRs for protein structure determination, measurement of protein dynamics, ligand binding studies, conformational fingerprinting, and the analysis of protein-protein interactions.

Professor Oliver Zerbe from University of Zürich stated: "The 1.2 GHz NMR enables the study G protein-coupled receptors (GPCRs) in greater detail to define dynamic behavior and conduct drug binding studies. The higher resolution and dispersion at 1.2 GHz enhance the study of interactions of drug candidates with GPCRs. Professor Ricarda Törner, who will join UZH in 2025, will greatly benefit from increased resolution in her studies of intrinsically disordered proteins. Similarly, Professor Sigel's group anticipates significant advantages for their RNA research."

Stephan Grzesiek, Professor of Structural Biology at Biozentrum Basel, who started the initiative for a Swiss high-field solution NMR, remarked: “Finally, we also have a highest-field NMR available for Swiss solution NMR. It will enable new NMR methods and explore the limits of detection in disease-relevant applications, such as GPCR signaling and cancer.”

His colleague, Professor Sebastian Hiller from Biozentrum Basel noted: "The 1.2 GHz NMR allows to study structures and dynamics of chaperone-client complexes at atomic resolution. These detailed descriptions will reveal biophysical laws governing chaperone function, with implications for neurodegenerative diseases, such as Parkinson’s."

Detlef Günther, Professor for Trace Element and Micro Analysis, and Vice President of Research at ETH Zürich (2015-2022) when the instrument was ordered, remarked: "We are excited to provide our scientists with this ultra-high field NMR. This collaboration will enable groundbreaking research in structural biology, furthering our understanding of complex biological systems.”

About Bruker Corporation – Leader of the Post-Genomic Era (Nasdaq: BRKR)

Bruker is enabling scientists and engineers to make breakthrough post-genomic discoveries and develop new applications that improve the quality of human life. Bruker’s high performance scientific instruments and high value analytical and diagnostic solutions enable scientists to explore life and materials at molecular, cellular, and microscopic levels. In close cooperation with our customers, Bruker is enabling innovation, improved productivity, and customer success in post-genomic life science molecular and cell biology research, in applied and biopharma applications, in microscopy and nanoanalysis, as well as in industrial and cleantech research, and next-gen semiconductor metrology in support of AI. Bruker offers differentiated, high-value life science and diagnostics systems and solutions in preclinical imaging, clinical phenomics research, proteomics and multiomics, spatial and single-cell biology, functional structural and condensate biology, as well as in clinical microbiology and molecular diagnostics. For more information, please visit www.bruker.com.

Celebrities embrace black and old Hollywood glamour for Golden Globes red carpet

Ariana Grande, Teyana Taylor, Timothée Chalamet and a sea of other stars said goodbye to color at this year's Golden Globes, opting instead for black. And many in the crowd stuck with tried and true old Hollywood glamour Sunday.

But even in basic black, the red carpet had plenty of personal flourishes and playful embellishments.

Risk-takers Taylor, a winner for “One Battle After Another,” and Jenna Ortega went with “whale tails,” aka the tops of thongs, peeking out the backs of their black gowns. Taylor did it with her custom slinky Schiaparelli gown that showed off a deep low-cut back with a glittery low-hanging bow thong. Ortega, keeping it goth, wore a Dilara Findikoglu gown with black shoulder tassels and a black thong.

“I thought that was such a cheeky callback to Y2K fashion,” InStyle Fashion Director Kevin Huynh said. “I was just like, wow, you wouldn’t expect that on a red carpet.”

Grande left behind her “Wicked” character's signature pink color for a black Vivienne Westwood couture dress but brought back her ponytail. Other notable celebrities in black included Ayo Edebiri, Selena Gomez, Miley Cyrus and Mia Goth.

Edebiri chose a black off-the-shoulder Chanel dress embellished with jewels on the shoulders from Matthieu Blazy’s Métiers d’Art 2026 show.

Celebrities held onto their gowns and watched their steps as they posed for photos on high stairs that served as the red carpet. Like the Met Gala, they lined up at the bottom and had to perilously climb their way up.

The 83rd Golden Globes gives a glimpse into how celebrities will showcase their original take on fashion as the awards season progresses. Since 1944, the show has honored the best in film and television.

The carpet, at The Beverly Hilton in Beverly Hills, California, is a chance for nominees to make a statement, though some are beholden to fashion houses who pay them as ambassadors.

Several, including George Clooney, wore Giorgio Armani. The fashion world lost Armani in September, but his eponymous brand lives on.

“It was nice to see so many attendees, including Julia Roberts and Kate Hudson, wearing the brand and pay tribute,” said Véronique Hyland, fashion features director for Elle.

Not all celebrities followed the black dress trend.

Host Nikki Glaser, who held hosting duty for the second time, wore a strapless satin blush-pink corseted satin gown with a full skirt by Zuhair Murad. Emma Stone stunned in a butter yellow Louis Vuitton skirt set.

“Sinners” star Wunmi Mosaku stunned in a flowy yellow Matthew Reisman gown. The mother-to-be revealed her baby bump on the carpet. Mosaku's co-star Hailee Steinfeld showed off her pregnant figure on the carpet in a peach colored gown.

Stars shone in metallics. “Sentimental Value” actor Renate Reinsve twirled on the carpet in a shimmery silver tasseled dress by Nicolas Ghesquiere for Louis Vuitton. Her co-star Elle Fanning's Gucci dress was embroidered with Norwegian flowers in honor of their Norwegian drama film.

Rising star Chase Infiniti reflected back the carpet and all its stars in her mirrored corseted gown by Nicolas Ghesquiere for Louis Vuitton.

“She’s now Louis Vuitton ambassador, which I think kind of shows her potential as a star,” Vanity Fair style writer José Criales-Unzueta said. “So much of what happens behind the scenes helps define what we’re looking at, whether it’s a deal, whether it sponsorship, whether it is brand ambassadorship.”

Claire Danes eschewed the academic, laid-back tailored looks of her “Beast in Me” character for an effortlessly elegant, couture gown designed by her close friend Zac Posen for GapStudio. Posen and Danes’ friendship and creative collaboration began in high school.

Posen began working on Danes' Golden Globe gown in November. As both creative director for Gap and GapStudio designer, Posen told The Associated Press that elevating the American essential into eveningwear is part of his creative process for the brand.

For Danes' look, Posen transformed the concept of the classic Gap pocket T-shirt into an off-white silk jersey couture gown with subtle bugle beaded detailing and embroidery. The shimmering dress featured a low scoop back and front pocket detail.

“Claire has a great elegance to her and is deeply inherently sophisticated, but yet cool,” Posen said. “Those elements fit perfectly with one of our icons that has built and defined our brands, the pocket tee.

Celebrities are keeping the sheer dressing trend alive with no signs of it slowing down. Lisa of Blackpink wore a black sheer Jacquemus dress, and Jennifer Lopez posed in a see-through dress by Jean-Louis Scherrer.

Jennifer Lawrence walked the carpet in a floral sheer dress by Sarah Burton at Givenchy and accessorized her look with a glamorous floral silk stole.

“Just to go out in a naked dress that leaves very little to the imagination is one thing but what Jennifer Lawrence did was such a romantic approach to it,” Huynh said. “I think that really says a lot to Sarah Burton, the designer of Givenchy. She is a woman designing for women.”

The male nominees didn’t stray too far from traditional looks. Colman Domingo pared down his typical colorful suits for a black suit by Valentino adorned with silver leaf brooches down his lapel. Timothée Chalamet, a winner for “Marty Supreme,” has become one to watch for his fashion choices. Departing from his past colorful looks, Chalamet wore a black velvet vest and jacket from Chrome Hearts with black Timberland boots. Chalamet's partner of three years, Kylie Jenner, did not walk the carpet with the actor, but viewers captured her in a custom silver column look by Ashi Studio. It was hand-embroidered with a fan-shaped crystal bead neckline.

After his viral premiere orange look for “Marty Supreme,” Criales-Unzueta said Chalamet decided on a more traditional movie star style by choosing all black.

“Heated Rivalry” star Hudson Williams brought the cummerbund back but with a laid-back twist. The breakout star paired a white-peak lapel dinner jacket with an unbuttoned silk shirt. Williams, along with his co-star Connor Storrie, were presenters during the ceremony. Storrie wore a black tuxedo jacket by Saint Laurent, with black tie and shades.

“It’s really just sexy takes on classic menswear with just those little bit of edge to things,” Huynh said.

Jenna Rosenstein, beauty director for Harper’s Bazaar, noted Storrie's hair transformation. He plastered his trademark curly locks into a shaggy, retro-inspired mullet. Among the women, beauty highlights included the swoopy bobs of Edebiri and Gomez, she said.

“If there’s one thing you should invest in after this carpet, it’s a really good round brush, a can of hairspray and a statement lipstick,” Rosenstein said.

AP writer Leanne Italie contributed to this report.

For more coverage of the 2026 Golden Globe Awards, visit: https://apnews.com/hub/golden-globe-awards