Conan O'Brien accepts Mark Twain Prize for humor as politics roils the Kennedy Center

WASHINGTON (AP) — On a night when half a dozen people made jokes about this being the last-ever Mark Twain Prize, Conan O'Brien made sure the ceremony at the John F. Kennedy Center for the Performing Arts ended on a high note.

O’Brien accepted the award for lifetime achievement in comedy Sunday night while acknowledging the backstage turmoil that hangs over the future of the cultural center in Washington.

O’Brien, 61, was named the 26th recipient of the Mark Twain Prize in mid-January, about three weeks before President Donald Trump upended the Kennedy Center by ousting longtime president Deborah Rutter and board chairman David Rubenstein. Trump dismissed the board of trustees and replaced them with loyalists, who then elected him as chairman.

On Sunday, O'Brien specifically thanked Rubenstein and Rutter — drawing an extended round of applause — and also Kennedy Center staffers who, he said, were “worried about what the future might bring.”

He said the example of Mark Twain's own life and career was particularly resonant at this moment in American history.

“Twain hated bullies. ... He punched up, not down, and he deeply empathized with the weak,” O'Brien said. “Twain loved America, but he knew it was deeply flawed.”

A Mark Twain impersonator then emerged from the audience. After a back-and-forth debate with O'Brien, he joined him on stage and the pair slow danced for a while. They were then joined by a dozen more Twain impersonators and previous Twain Prize recipient Adam Sandler for a raucous rendition of Neil Young’s “Rockin in the Free World.”

That musical ending capped off a night when the uncertain fate of the Kennedy Center itself was woven through the multiple tributes and testimonials to O’Brien.

“I think it would be insane not to address the elephant in the room,” comic Nikki Glaser said on the red carpet before the ceremony. “It’s in the air tonight. This night is about Conan, but it can be both.”

Once the festivities began, Stephen Colbert joked that the Kennedy Center had announced two new board members: Bashar Assad, the ousted president of Syria, and Skeletor, a fictional supervillain.

John Mulaney quipped that the entire building would soon be renamed “the Roy Cohn Pavilion” after one of Trump’s mentors. And Sarah Silverman made multiple Trump jokes that were too vulgar to print.

Trump, in announcing the Kennedy Center changes, posted on social media that those who were dismissed "do not share our Vision for a Golden Age in Arts and Culture.”

How that vision takes shape remains to be seen, but Trump has spoken about wanting to book more Broadway shows there and floated the idea of granting Kennedy Center Honors status to actor Sylvester Stallone and singer-songwriter Paul Anka.

Into this maelstrom stepped O'Brien, whose comedic persona has never been particularly political. The comic has always tended more toward goofiness and self-deprecation. But he has also leaned into sensitive societal issues at times. In 2011, O'Brien officiated a gay wedding live on his show, overseeing the marriage of his longtime costume designer Scott Cronick and his partner David Gorshein.

O’Brien vaulted into the spotlight from near-total obscurity in 1993 when he was chosen to replace David Letterman as host of “Late Night” despite no significant on-camera experience. The former Harvard Lampoon editor had spent the previous years as a writer for “Saturday Night Live” and “The Simpsons,” appearing on camera only as an occasional background extra in “SNL” skits.

He went on to host “Late Night” for 16 years, longer than any other host. O'Brien was later tapped to replace Jay Leno as host of “The Tonight Show,” but that experiment ended in public failure. After seven months of declining ratings, NBC executives brought Leno back for a new show that would bump “The Tonight Show” back. O’Brien refused to accept the move, leading to a public spat that ended with a multimillion-dollar payout for O’Brien and his staff to exit the network in early 2010.

O'Brien went on to host another talk show on the cable station TBS, while launching successful podcasts and travel shows. He is currently on a late-career elder statesman hot streak. His travel series, “Conan O’Brien Must Go,” drew popular and critical acclaim, with a second season coming. His recent gig hosting the Academy Awards was so well received that the producers announced they are bringing him back next year.

In the wake of Trump's takeover of the Kennedy Center, several artists, including the producers of “Hamilton” and actress and writer Issa Rae, announced they were canceling appearances at the venue.

Others have chosen to perform while making their sentiments known from the stage. Leftist comic W. Kamau Bell directly addressed the controversy in his performance just days after the shake-up. Earlier this month, cellist Erin Murphy Snedecor ended her set with a performance of the Woody Guthrie protest anthem “All You Fascists Bound to Lose.”

Other comedians receiving the lifetime achievement award include both Letterman and Leno, along with George Carlin, Whoopi Goldberg, Bob Newhart, Carol Burnett, Bill Murray and Dave Chappelle.

The ceremony will be streamed on Netflix on May 4.

Comedian Conan O'Brien walks out on stage at the start of the 25th Annual Mark Twain Prize for American Humor Celebrating Conan O'Brien, Sunday, March 23, 2025, at the Kennedy Center for the Performing Arts in Washington. (AP Photo/Kevin Wolf)

Comedian Conan O'Brien walks out on stage at the start of the 25th Annual Mark Twain Prize for American Humor Celebrating Conan O'Brien, Sunday, March 23, 2025, at the Kennedy Center for the Performing Arts in Washington. (AP Photo/Kevin Wolf)

Triumph the Insult Comic Dog speaks at the start of the 25th Annual Mark Twain Prize for American Humor Celebrating Conan O'Brien, Sunday, March 23, 2025, at the Kennedy Center for the Performing Arts in Washington. (AP Photo/Kevin Wolf)

Netflix co-CEO Ted Sarandos, left, shakes hands with Reggie Watts as they arrive at the 25th Annual Mark Twain Prize for American Humor Celebrating Conan O'Brien, Sunday, March 23, 2025, at the Kennedy Center for the Performing Arts in Washington. (AP Photo/Kevin Wolf)

Nikki Glaser, left, and her mom, Julie Glaser, center, look as her dad, Edward Glaser, right, stands on Nikki's dress as they arrive at the 25th Annual Mark Twain Prize for American Humor Celebrating Conan O'Brien, Sunday, March 23, 2025, at the Kennedy Center for the Performing Arts in Washington. (AP Photo/Kevin Wolf)

Comedian Conan O'Brien, fourth from right, is applauded as he takes his seat at the start of the 25th Annual Mark Twain Prize for American Humor Celebrating Conan O'Brien, Sunday, March 23, 2025, at the Kennedy Center for the Performing Arts in Washington. (AP Photo/Kevin Wolf)

Comedian Conan O'Brien, center, and his wife, Liza Powel O'Brien, looks out on the crowd at the start of the 25th Annual Mark Twain Prize for American Humor Celebrating Conan O'Brien, Sunday, March 23, 2025, at the Kennedy Center for the Performing Arts in Washington. (AP Photo/Kevin Wolf)

Brian McCann, dressed as the FedEx Pope, looks to Conan O'Brien at the start of the 25th Annual Mark Twain Prize for American Humor Celebrating Conan O'Brien, Sunday, March 23, 2025, at the Kennedy Center for the Performing Arts in Washington. (AP Photo/Kevin Wolf)

Comedian Conan O'Brien walks out on stage at the start of the 25th Annual Mark Twain Prize for American Humor Celebrating Conan O'Brien, Sunday, March 23, 2025, at the Kennedy Center for the Performing Arts in Washington. (AP Photo/Kevin Wolf)

President Donald Trump attends a board meeting at the John F. Kennedy Center for the Performing Arts in Washington, Monday, March 17, 2025. (Pool via AP)

President Donald Trump tours the John F. Kennedy Center for the Performing Arts in Washington, Monday, March 17, 2025. (Pool via AP)

FILE - Conan O'Brien takes part in a panel discussion during the South by Southwest Conference and Festival, March 11, 2025, in Austin, Texas. (Photo by Jack Plunkett/Invision/AP, File)

Protesters confronted federal officers in Minneapolis on Thursday, a day after a woman was fatally shot by an Immigration and Customs Enforcement officer.

The demonstrations came amid heightened tensions after President Donald Trump's administration dispatched 2,000 officers and agents to Minnesota for its latest immigration crackdown.

Across the country, another city was reeling after federal immigration officers shot and wounded two people in a vehicle outside a hospital in Portland, Oregon.

The killing of 37-year-old Renee Good in Minneapolis on Wednesday set off a clash between federal and state officials over whether the shooting appeared justified and whether a Minnesota law enforcement agency had jurisdiction to investigate.

Here's what is known about the shooting:

The woman was shot in her SUV in a residential neighborhood south of downtown Minneapolis, about a mile (1.6 kilometers) from where police killed George Floyd in 2020. Videos taken by bystanders and posted online show an officer approaching a vehicle stopped in the middle of the road, demanding the driver open the door and grabbing the handle.

The Honda Pilot begins to pull forward and a different ICE officer standing in front of the vehicle draws his gun and immediately fires at least two shots at close range, jumping back as the vehicle moves toward him.

It is not clear from the videos if the officer gets struck by the SUV, which speeds into two cars parked on a curb before stopping.

It’s also not clear what happened in the lead-up to the shooting.

Homeland Security Secretary Kristi Noem said the SUV was part of a group of protesters that had been harassing agents and “impeding operations” that morning. She said agents had freed one of their vehicles that was stuck in snow and were leaving the area when the confrontation and shooting occurred.

No video has emerged to corroborate Noem’s account. Bystander video from the shooting scene shows a sobbing woman who says the person shot was her wife. That woman hasn’t spoken publicly to give her version of events.

Good died of gunshot wounds to the head.

A U.S. citizen born in Colorado, Good described herself on social media as a “poet and writer and wife and mom." Her ex-husband said Good had just dropped off her 6-year-old son at school Wednesday and was driving home when she encountered ICE agents on a residential street.

He said Good and her current partner moved to Minneapolis last year from Kansas City, Missouri.

Good's killing is at least the fifth death to result from the aggressive U.S. immigration crackdown the Trump administration launched last year.

Noem said Thursday that there would be a federal investigation into the shooting, though she again called the woman’s actions “domestic terrorism.”

“This vehicle was used to hit this officer,” Noem said. “It was used as a weapon, and the officer feels as though his life was in jeopardy.”

Vice President JD Vance said the shooting was justified and referred to Good's death as “a tragedy of her own making.”

Minneapolis Police Chief Brian O’Hara gave no indication that the driver was trying to harm anyone when he described the shooting to reporters Wednesday. Minneapolis Mayor Jacob Frey said he had watched videos of the shooting that show it was avoidable.

The agent who shot Good is an Iraq War veteran who has served for nearly two decades in the Border Patrol and U.S. Immigration and Customs Enforcement, according to records obtained by The Associated Press.

Jonathan Ross has been a deportation officer with ICE since 2015, records show. He was seriously injured this summer when he was dragged by the vehicle of a fleeing suspect whom he shot with a stun gun.

Federal officials have not named the officer. But Noem said he was dragged by a vehicle in June, and a department spokesperson confirmed Noem was referring to the Bloomington, Minnesota, case in which documents identified the injured officer as Ross.

Court documents say Ross got his arm stuck in the window as a driver fled arrest in that incident. Ross was dragged 100 yards (91 meters), and cuts to his arm required 50 stitches.

According to police, officers initially responded to a report of a shooting outside a hospital Thursday afternoon.

Minutes later police heard that a man who had been shot was asking for help in a residential area a couple of miles away. Officers went there and found a man and a woman with gunshot wounds. Officers determined they were wounded in a shooting with federal agents.

Police Chief Bob Day said the FBI was leading the investigation and he had no details about events that led to the shooting.

The Department of Homeland Security said the vehicle’s passenger was “a Venezuelan illegal alien affiliated with the transnational Tren de Aragua prostitution ring” who was involved in a recent shooting. When agents identified themselves to the occupants during a “targeted vehicle stop,” the driver tried to run them over, the department said. An agent fired in self-defense, it said.

There was no immediate independent corroboration of that account or of any gang affiliation of the vehicle’s occupants.

Trump and his allies have consistently blamed Tren de Aragua for being at the root of violence and illicit drug dealing in some U.S. cities.

Drew Evans, head of Minnesota Bureau of Criminal Apprehension, said Thursday that federal authorities have denied the state agency access to evidence in the Good case, barring the state from investigating the shooting alongside the FBI.

Minnesota Gov. Tim Walz demanded that state investigators be given a role, telling reporters that residents would otherwise have a difficulty accepting the findings of federal law enforcement.

“And I say that only because people in positions of power have already passed judgment from the president to the vice president to Kristi Noem,” Walz said.

Noem denied that Minnesota authorities were being shut out, saying: “They don’t have any jurisdiction in this investigation.”

Dozens of protesters gathered Thursday morning outside a Minneapolis federal building being used as a base for the immigration crackdown. Border Patrol officers fired tear gas and doused demonstrators with pepper spray to push them back from the gate.

Area schools were closed as a safety precaution.

Protests were also planned across the U.S. in cities including New York, New Orleans and Seattle.

Associated Press writer Audrey McAvoy contributed.

Protesters confront federal agents outside the Bishop Henry Whipple Federal Building, Thursday, Jan. 8, 2026, in Minneapolis, Minn. (AP Photo/Tom Baker)

People gather for a vigil after an Immigration and Customs Enforcement officer shot and killed a motorist earlier in the day, Wednesday, Jan. 7, 2026, in Minneapolis. (AP Photo/Bruce Kluckhohn)

People participate in a protest and vigil after an Immigration and Customs Enforcement officer shot and killed a woman in Minneapolis, on Wednesday, Jan. 7, 2026. (Christopher Katsarov/The Canadian Press via AP)