Casas hits a bases-loaded single off Green Monster in 10th to lift Red Sox past White Sox 4-3

BOSTON (AP) — Triston Casas hit a bases-loaded single off the Green Monster to drive in the winning run with one out in the 10th inning on Saturday, lifting the Boston Red Sox to a 4-3 victory over the Chicago White Sox.

Rafael Devers hit a three-run homer for Boston, which won its fourth straight.

Luis Robert Jr. hit a two-run shot for the White Sox, who lost their sixth in a row and fell to 4-16 and 0-8 on the road, the worst road start in team history.

The Red Sox nearly wasted a scoreless outing by Garrett Crochet, who took a no-hitter into the eighth inning of a victory against the White Sox in his previous start. He gave up four singles while striking out seven over six innings on Saturday.

Boston took a 3-0 lead when Devers hit a fastball from Shane Smith that left Fenway Park over the Monster in the fifth.

Chicago tied it with a three-run seventh. Chase Meidroth had an RBI single before Robert hit a hanging sweeper.

Smith gave up three runs over 4 2/3 innings in his fourth major league start. The 25-year-old righty, who grew up about 30 minutes north of Fenway in Danvers, Massachusetts, hit three batters in his second straight start against Boston.

Garrett Whitlock (1-0) got the win.

Struggling Casas, who entered the day hitting .172, hit the second pitch halfway up the Monster against rookie Mike Vasil (0-1), who had his first major league decision.

Crochet has allowed only a run over 13 1/3 innings in his last two starts, both against his former team, with 18 strikeouts.

White Sox RHP Sean Burke (1-3, 7.56 ERA) is set to face struggling Red Sox righty Tanner Houck (0-2, 9.16), who was tagged for 12 runs in only 2 1/3 innings against Tampa Bay on Monday.

AP MLB: https://apnews.com/hub/mlb

Boston Red Sox's Rafael Devers celebrates as he begins to run the bases after hitting a three-run home run in the fifth inning of a baseball game against the Chicago White Sox, Saturday, April 19, 2025, in Boston. (AP Photo/Steven Senne)

Boston Red Sox's Rafael Devers, left, celebrates as he scores on his three-run home run in front of Chicago White Sox catcher Edgar Quero, right, in the fifth inning of a baseball game, Saturday, April 19, 2025, in Boston. (AP Photo/Steven Senne)

Boston Red Sox's Ceddanne Rafaela is hit by a pitch in the second inning of a baseball game against the Chicago White Sox, Saturday, April 19, 2025, in Boston. (AP Photo/Steven Senne)

Boston Red Sox's Ceddanne Rafaela reacts after he is hit by a pitch in the second inning of a baseball game against the Chicago White Sox, Saturday, April 19, 2025, in Boston. (AP Photo/Steven Senne)

Boston Red Sox's Rafael Devers, right, follows through on his swing as he hits a three-run home run in front of Chicago White Sox catcher Edgar Quero, left, in the fifth inning of a baseball game, Saturday, April 19, 2025, in Boston. (AP Photo/Steven Senne)

Boston Red Sox's Rafael Devers, center, wears a mascot mask as he celebrates his three-run home with teammates in the dugout in the fifth inning of a baseball game against the Chicago White Sox, Saturday, April 19, 2025, in Boston. (AP Photo/Steven Senne)

Chicago White Sox's Shane Smith delivers a pitch to a Boston Red Sox batter in the first inning of a baseball game, Saturday, April 19, 2025, in Boston. (AP Photo/Steven Senne)

Boston Red Sox's Garrett Crochet delivers a pitch to a Chicago White Sox batter in the first inning of a baseball game, Saturday, April 19, 2025, in Boston. (AP Photo/Steven Senne)

SAN FRANCISCO--(BUSINESS WIRE)--Jan 12, 2026--

Owkin, an AI company on a mission to solve the complexity of biology, today announced that its interoperable Pathology Explorer AI agent will be included in the launch of Claude for Healthcare and Life Sciences (HCLS) by Anthropic. This marks the first time a highly specialized, world-leading biological agent trained primarily on multimodal patient data is accessible through the Model Context Protocol (MCP) to a broad audience of healthcare and life sciences professionals.

This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20260112836381/en/

The collaboration enables seamless integration of Owkin's advanced pathology analysis capabilities into Claude's AI platform, making sophisticated biological intelligence accessible to healthcare organizations, pharmaceutical companies, and research institutions within their Claude workflows, without requiring system overhauls or proprietary process changes.

"I believe this agentic interoperability is the future of biopharma discoveries," said Thomas Clozel, M.D., CEO and co-founder of Owkin. "By making our best-in-class agents trained on patient data from the world's leading hospitals accessible through portals like Claude for HCLS, we're enabling the biggest healthcare organizations to accelerate their research in ways that weren't possible before. This is about putting patient data first when training AI and making that intelligence universally available to cure disease faster."

Pathology Explorer is part of Owkin’s K Pro community of agents for biology. This agent identifies and locates cell and tissue types, enabling spatially-aware analysis of patient tissue images. Using the agent, users can analyze tumors and their microenvironments and study inflammation patterns. Pathology Explorer enables the extraction of biomarkers from digitized pathology images to generate and validate hypotheses through cohort-level survival analysis — a critical capability for accelerating drug discovery, clinical trial design, and development of digital diagnostic tools. The agent leverages proprietary, best-in-class AI models that have been trained on patient histopathology data sourced from Owkin's network spanning over 800 hospitals from 104 healthcare centers, enabling it to deliver high-accuracy analysis.

Owkin MCP Integration Enables Seamless Access

Owkin has developed industry standard MCP encoding specifically designed to allow its proprietary K Pro agents to integrate seamlessly with Claude's interface. Pathology Explorer is the first agent from Owkin's interoperable agentic AI infrastructure for biology to be offered for external integration, demonstrating the company's commitment to building an open, API-first infrastructure that can serve as the universal foundation for advancing drug development.

Claude for Healthcare and Life Sciences is designed to accelerate preclinical R&D (including bioinformatics, protocol development, and literature synthesis), streamline clinical trial operations and data management, and support regulatory affairs and submission preparation. The integration of Owkin's Pathology Explorer extends these capabilities by enabling deep biological reasoning specifically trained on real patient data.

This is the third in a series of major announcements Owkin is unveiling, including agentic infrastructure for biology (Owkin's new interoperable agentic infrastructure for biopharma) and a strategic collaboration with NVIDIA to enhance OwkinZero, Owkin's biological large reasoning model.

About Owkin

Owkin is an AI company with $300 million in funding on a mission to solve the complexity of biology. It is building the first Biological Artificial Super Intelligence (BASI) by combining powerful biological large reasoning models, multimodal patient data, and agentic software. At the heart of this system is Owkin K, an AI copilot, and OwkinZero, Owkin's biological large reasoning model, used by researchers, clinicians, and drug developers to better understand biology, validate scientific hypotheses, and deliver better diagnostics and therapies faster. Owkin has exclusive access to multimodal patient data from more than 800 hospitals collected over a decade and partners with eight of the 10 largest pharmaceutical companies. For more information, visit www.owkin.com.

Owkin Media Kit:https://www.owkin.com/press-kit

Owkin's Specialized Biological AI Agent Pathology Explorer Launches with Anthropic's Claude for Healthcare and Life Sciences.