Asia's First Real-World ctDNA-MRD Study Strengthens Evidence for Cost-Effective Cancer Monitoring

A landmark study recently published in March 2025 by JCO Oncology Advances, demonstrates the potential of K-TRACK^TM in monitoring treatment response and assessing recurrence risk among 623 Solid-Tumor Patients of six cancer types (lung, colorectal, breast, gastric, liver, or ovarian cancer).⁽¹⁾

SINGAPORE, April 19, 2025 /PRNewswire/ -- Gene Solutions, a biotechnology company dedicated to advancing precision oncology in Asia, is excited to announce the publication of a pioneering real-world study in JCO Oncology Advances, validating circulating tumor DNA (ctDNA) as a strong prognostic biomarker to effectively monitor patients during cancer management.

K-TRACK^TM is a breakthrough in affordable tumor profiling and personalized cancer monitoring leveraging ctDNA technology. The study, the first of its kind in Asia, confirms K-TRACK^TM's clinical value across both early and advanced stages of cancer. The test can detect residual cancer cells (Minimal Residual Disease – MRD) after radical treatment, predict recurrence months earlier than traditional methods, and monitor treatment responses effectively. This innovative dual assay offers hope to patients in underserved regions where access to advanced diagnostic technologies remains a challenge.

Asia represents nearly 50% of global cancer cases, with incidence rates rising at an alarming pace. While some developed markets in the region have seen improvements in cancer mortality rates, Southeast Asia continues to experience high death rates, predominantly driven by cancer recurrence. ^(2,3)

Research has demonstrated the clinical prognostic value of ctDNA in a variety of cancer types both before and after treatment  ⁽⁴⁾.  Despite this potential, the adoption of ctDNA testing remains limited due to factors such as high costs, the absence of standardized methods and insufficient clinical utility of real-world data.

K-TRACK^TM was developed as an affordable, reliable personalized test for monitoring ctDNA across multiple solid tumors. It is designed to facilitate early detection of cancer recurrence and provide real-time monitoring of treatment responses. Validated in both clinical trials and real-world studies, K-TRACK^TM is built for meaningful impact in cancer care while ensuring accessibility. Here's how we make it work:

• Cost-Effective Innovation: K-TRACK^TM uniquely combines streamlined tumor profiling of 155 of the most common driver mutations with personalized ctDNA monitoring based on tumor-specific variants, significantly enhancing the affordability and accuracy for routine clinical practice.
• Comprehensive approach of genomic profiling and minimal residual disease tracking: The initial tumor profiling results guide the selection of targeted therapies and immunotherapies, while subsequent serial ctDNA monitoring provides early prediction of recurrence and assess treatment effectiveness.
• Designed for Real-World Conditions: K-TRACK^TM is engineered to provide reliable results even from challenging samples such as degraded tissue or delayed blood storage, making it ideal for complex clinical settings.

Real-world monitoring of ctDNA has proven effective in predicting early cancer recurrence, allowing for timely interventions and improved patient outcomes. In both early and advanced-stage cancer patients, K-TRACK^TM has demonstrated high accuracy in predicting recurrence. Following surgery, 84.4% [CA1]  of patients with ctDNA-positive results eventually relapsed, while an impressive 96.3% [CA2]  of those with ctDNA-negative results remained cancer-free. Moreover, the test could detect relapse up to 5.5-19.5 months earlier than clinical diagnosis by imaging methods. Simultaneously, the six case studies presented illustrated the clinical utility of ctDNA monitoring in predicting treatment response, informing adjuvant chemotherapy decisions, and identifying new resistant mutations to current targeted treatment. Thus, empowering clinicians with real-time, actionable insights to inform treatment decisions.

A Vision for Equitable Care

"Access to cutting-edge, personalized cancer treatment and monitoring—based on tumor genomic profiling— too often depends on where you live or what you can afford," said Dr. Lan N. Tu, Principal Investigator at Gene Solutions. "Our mission with K-TRACK^TM is to close that gap by providing an affordable and precise real-time solution for routine clinical use."

Gene Solutions is actively investing in two key areas:

1. On-going Clinical Trials and Real-World Studies:

The company is conducting comprehensive research to validate the role of ctDNA across various cancer types and treatment stages. This includes evaluating responses to TKIs and immune checkpoint inhibitors (ICIs) in lung cancer, neoadjuvant therapy in breast cancer, total neoadjuvant therapy in rectal cancer, and the use of biomarkers to inform immunotherapy treatment decisions in advanced cancers.

2. Biopharma Collaborations:

Gene Solutions is actively pursuing partnerships with biopharmaceutical companies to provide innovative solutions aimed at accelerating drug development across a range of therapeutic modalities. As the scientific evidence supporting ctDNA continues to grow, Gene Solutions is committed to expanding its research and fostering collaborations with current and new partners to explore new applications in cancer care. The company's direction aligns with the FDA's recommendation on ctDNA use as a biomarker in the development of curative-intent therapies for solid tumors which states: "ctDNA as a biomarker has a number of potential regulatory and clinical uses in the early-stage setting that may assist and expedite drug development." ⁽⁵⁾

About Gene Solutions

Gene Solutions, a multinational biotech company in Asia, is leading the way in leveraging advanced AI and ctDNA technologies for innovative cancer detection solutions. The company partners with over 4,500 hospitals and clinics across Southeast Asia and employs a dedicated team of approximately 250 biology experts and technicians out of a total of 700 employees.

With more than 50 peer-reviewed publications and over 50 multi-center studies conducted across the region, Gene Solutions is recognized for its proprietary research and CAP-accredited next-generation sequencing (NGS) laboratories in Singapore and Vietnam. By integrating multi-dimensional genomics with AI-driven methodologies, the company is committed to transforming cancer care and improving patient outcomes.

** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **

Asia's First Real-World ctDNA-MRD Study Strengthens Evidence for Cost-Effective Cancer Monitoring

Asia's First Real-World ctDNA-MRD Study Strengthens Evidence for Cost-Effective Cancer Monitoring

 

A Legendary Gathering: 300+ Olympic and Paralympic Icons 'Ignite' the Athlete and Fan Journey to LA28
at LA Memorial Coliseum

ASSETS: Links to hi-res photos and video follow.

VIDEO: Hi-res video b-roll footage of LA28 Celebration on Eve of Ticket Registration Opening
Link: EXTERNAL_LA28 Olympic Ticketing Registration Broll_2026_01_14
Password: @Olympic_Ticketing-Registration#LA28
Link Expiration: 1/19/26

STILL IMAGES: Getty images from LA28 Celebration on Eve of Ticket Registration Opening
Link: https://dam.gettyimages.com/s/63qk5pxpk85x7gv6f9tzjpst

LOS ANGELES, Jan. 14, 2026 /PRNewswire/ -- Starting today at 10 a.m. ET/ 7 a.m. PT, sports fans worldwide can register for the LA28 Ticket Draw* and take their first step toward witnessing Olympic and Paralympic history. On the eve of this milestone moment, LA28 hosted more than 300 Olympians and Paralympians – representing 28 different Games dating back to 1960 – at the historic LA Memorial Coliseum in the interest of continuing to build an athlete-centric Games, marking one of the largest assemblies of Olympic and Paralympic athletes ever gathered outside of competition.

"LA28 is ready to welcome the world and the most spectacular athletes from every corner of it for what will be the greatest Games in history," said LA28 Chief Executive Officer, Reynold Hoover. "A ticket to the Games is more than just a seat in the stands. It's an opportunity to witness history and be part of the awe-inspiring moments where we celebrate the best of humanity and experience unity through the power of sport."

How the Ticketing Process Works: Register Today at Tickets.LA28.org
Registration is the first step for a chance to secure a time slot to purchase tickets. Once registered, participants will be entered into a ticket draw, which will randomly assign time slots to purchase tickets throughout multiple future ticket drops.

Here are the key details of the ticketing process:

• Starting today, January 14 (10 a.m. EST / 7 a.m. PST), through March 18, fans around the world can register for the LA28 Ticket Draw and the opportunity to be selected for a time slot when Olympic tickets go on sale.
• Time slots to purchase during Drop 1 will run from April 9 to April 19, 2026.
• Fans will be notified by email from March 31 to April 7, 2026 if they've been assigned a time slot.
• There will be rolling ticket drops starting in April 2026. Fans are encouraged to register today for the best choice of tickets and events, as capacity may be filled or limited in subsequent drops. Paralympic tickets will go on sale in 2027.
• Fans only need to register once to be entered for future ticket draws and Paralympic draws once tickets for this event go on sale later in 2027. Those not selected for the first drop will automatically be entered into future draws.
• Anyone who wants access to tickets – whether for one sport or multiple events – will need to register for the LA28 Ticket Draw.
• If registrants selected for a time slot do not purchase the maximum amount of tickets allotted for the Olympic Games (12 per person) during that slot, they will automatically be entered into subsequent ticket draws.
• Tickets to the Opening and Closing Ceremony will be available in Drop 1.
• Tickets start at $28, and details on pricing for all categories will be available when Drop 1 opens in April 2026.

Introducing the LA & OKC Locals Presale*
The Locals Presale runs from April 2 to April 6, 2026 before Drop 1 opens on April 9. Residents who register for the ticket draw with billing postal codes in the following Southern California and Oklahoma counties will automatically be entered into the draw for the presale and will have a chance to secure a time slot during a special early-access window prior to tickets going on sale to the general public: Los Angeles, Orange, Riverside, Ventura, San Bernardino, Oklahoma, Canadian and Cleveland.

The LA28 ticket process will be powered by LA28's Official Ticketing Service Provider AXS and EVENTIM. In addition to individual tickets, curated ticket-inclusive hospitality experiences and packages from On Location will also go on sale in 2026. 

Options for Everyone
LA28 is committed to ensuring that tickets to the Games are accessible to everyone, especially for those in the Los Angeles community. To achieve this goal, LA28 is ensuring fans have a wide array of ticket options — from single tickets that will start at $28 to premium hospitality experiences — to witness the Games firsthand. This includes at least one million tickets priced at $28 and a third of tickets priced under $100.

In addition, LA28 launched a fundraising effort in November in which local sports teams, philanthropists and partners will contribute donations to fund free tickets that will go directly into the hands of local organizations to distribute within their communities.

To register for the LA28 Ticket Draw, visit Tickets.LA28.org.

In recognition of Visa's long-standing partnership with the Olympic and Paralympic Games, Visa is the Official Way to Pay.

ABOUT THE LA28 OLYMPIC AND PARALYMPIC GAMES
LA28 will bring the Olympic and Paralympic Games to Los Angeles in 2028, uniting more than 15,000 of the world's greatest athletes in a celebration of sport, culture and human potential. Set against a diverse collection of venues only Southern California can deliver, from the Pacific Ocean to Hollywood stages to world-class arenas, Los Angeles will become the third city ever to host three Olympic Games, following 1932 and 1984, and will also host its first ever Paralympic Games. The LA28 Games will celebrate historic milestones including becoming the first Olympic Games in history to feature more women athletes than men, the debut of new Olympic and Paralympic sports and becoming the first Games since 1948 to not build any new permanent infrastructure. Operating as an independently funded, non-profit organization, LA28 has built a strong foundation of successful commercial partnerships alongside licensing, hospitality, ticketing and with the support of the International Olympic Committee.

*NO PURCHASE OR PAYMENT REQUIRED TO REGISTER, ENTER OR WIN. RESTRICTIONS APPLY. ELIGIBILITY SUBJECT TO VERIFICATION. MUST BE AT LEAST 18 YEARS OF AGE AT TIME OF REGISTRATION. TERMS, DEADLINES AND PROCESS SUBJECT TO CHANGE. OFFICIAL TERMS FOR THE LA28 TICKET DRAW ARE AVAILABLE HERE. OFFICIAL TERMS FOR THE LA & OKC LOCALS PRESALE ARE AVAILABLE HERE. TICKET AVAILABILITY NOT GUARANTEED AND TICKET PURCHASES SUBJECT TO ADDITIONAL TERMS AND REQUIREMENTS HERE.

 

 

A Legendary Gathering: 300+ Olympic and Paralympic Icons 'Ignite' the Athlete and Fan Journey to LA28
at LA Memorial Coliseum

ASSETS: Links to hi-res photos and video follow.

VIDEO: Hi-res video b-roll footage of LA28 Celebration on Eve of Ticket Registration Opening
Link: EXTERNAL_LA28 Olympic Ticketing Registration Broll_2026_01_14
Password: @Olympic_Ticketing-Registration#LA28
Link Expiration: 1/19/26

STILL IMAGES: Getty images from LA28 Celebration on Eve of Ticket Registration Opening
Link: https://dam.gettyimages.com/s/63qk5pxpk85x7gv6f9tzjpst

LOS ANGELES, Jan. 14, 2026 /PRNewswire/ -- Starting today at 10 a.m. ET/ 7 a.m. PT, sports fans worldwide can register for the LA28 Ticket Draw* and take their first step toward witnessing Olympic and Paralympic history. On the eve of this milestone moment, LA28 hosted more than 300 Olympians and Paralympians – representing 28 different Games dating back to 1960 – at the historic LA Memorial Coliseum in the interest of continuing to build an athlete-centric Games, marking one of the largest assemblies of Olympic and Paralympic athletes ever gathered outside of competition.

"LA28 is ready to welcome the world and the most spectacular athletes from every corner of it for what will be the greatest Games in history," said LA28 Chief Executive Officer, Reynold Hoover. "A ticket to the Games is more than just a seat in the stands. It's an opportunity to witness history and be part of the awe-inspiring moments where we celebrate the best of humanity and experience unity through the power of sport."

How the Ticketing Process Works: Register Today at Tickets.LA28.org
Registration is the first step for a chance to secure a time slot to purchase tickets. Once registered, participants will be entered into a ticket draw, which will randomly assign time slots to purchase tickets throughout multiple future ticket drops.

Here are the key details of the ticketing process:

• Starting today, January 14 (10 a.m. EST / 7 a.m. PST), through March 18, fans around the world can register for the LA28 Ticket Draw and the opportunity to be selected for a time slot when Olympic tickets go on sale.
• Time slots to purchase during Drop 1 will run from April 9 to April 19, 2026.
• Fans will be notified by email from March 31 to April 7, 2026 if they've been assigned a time slot.
• There will be rolling ticket drops starting in April 2026. Fans are encouraged to register today for the best choice of tickets and events, as capacity may be filled or limited in subsequent drops. Paralympic tickets will go on sale in 2027.
• Fans only need to register once to be entered for future ticket draws and Paralympic draws once tickets for this event go on sale later in 2027. Those not selected for the first drop will automatically be entered into future draws.
• Anyone who wants access to tickets – whether for one sport or multiple events – will need to register for the LA28 Ticket Draw.
• If registrants selected for a time slot do not purchase the maximum amount of tickets allotted for the Olympic Games (12 per person) during that slot, they will automatically be entered into subsequent ticket draws.
• Tickets to the Opening and Closing Ceremony will be available in Drop 1.
• Tickets start at $28, and details on pricing for all categories will be available when Drop 1 opens in April 2026.

Introducing the LA & OKC Locals Presale*
The Locals Presale runs from April 2 to April 6, 2026 before Drop 1 opens on April 9. Residents who register for the ticket draw with billing postal codes in the following Southern California and Oklahoma counties will automatically be entered into the draw for the presale and will have a chance to secure a time slot during a special early-access window prior to tickets going on sale to the general public: Los Angeles, Orange, Riverside, Ventura, San Bernardino, Oklahoma, Canadian and Cleveland.

The LA28 ticket process will be powered by LA28's Official Ticketing Service Provider AXS and EVENTIM. In addition to individual tickets, curated ticket-inclusive hospitality experiences and packages from On Location will also go on sale in 2026. 

Options for Everyone
LA28 is committed to ensuring that tickets to the Games are accessible to everyone, especially for those in the Los Angeles community. To achieve this goal, LA28 is ensuring fans have a wide array of ticket options — from single tickets that will start at $28 to premium hospitality experiences — to witness the Games firsthand. This includes at least one million tickets priced at $28 and a third of tickets priced under $100.

In addition, LA28 launched a fundraising effort in November in which local sports teams, philanthropists and partners will contribute donations to fund free tickets that will go directly into the hands of local organizations to distribute within their communities.

To register for the LA28 Ticket Draw, visit Tickets.LA28.org.

In recognition of Visa's long-standing partnership with the Olympic and Paralympic Games, Visa is the Official Way to Pay.

ABOUT THE LA28 OLYMPIC AND PARALYMPIC GAMES
LA28 will bring the Olympic and Paralympic Games to Los Angeles in 2028, uniting more than 15,000 of the world's greatest athletes in a celebration of sport, culture and human potential. Set against a diverse collection of venues only Southern California can deliver, from the Pacific Ocean to Hollywood stages to world-class arenas, Los Angeles will become the third city ever to host three Olympic Games, following 1932 and 1984, and will also host its first ever Paralympic Games. The LA28 Games will celebrate historic milestones including becoming the first Olympic Games in history to feature more women athletes than men, the debut of new Olympic and Paralympic sports and becoming the first Games since 1948 to not build any new permanent infrastructure. Operating as an independently funded, non-profit organization, LA28 has built a strong foundation of successful commercial partnerships alongside licensing, hospitality, ticketing and with the support of the International Olympic Committee.

*NO PURCHASE OR PAYMENT REQUIRED TO REGISTER, ENTER OR WIN. RESTRICTIONS APPLY. ELIGIBILITY SUBJECT TO VERIFICATION. MUST BE AT LEAST 18 YEARS OF AGE AT TIME OF REGISTRATION. TERMS, DEADLINES AND PROCESS SUBJECT TO CHANGE. OFFICIAL TERMS FOR THE LA28 TICKET DRAW ARE AVAILABLE HERE. OFFICIAL TERMS FOR THE LA & OKC LOCALS PRESALE ARE AVAILABLE HERE. TICKET AVAILABILITY NOT GUARANTEED AND TICKET PURCHASES SUBJECT TO ADDITIONAL TERMS AND REQUIREMENTS HERE.

 

** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **

REGISTRATION FOR THE LA28 TICKET DRAW OPENS TODAY FOR TICKETS TO ALL OLYMPIC SPORTS