DALLAS--(BUSINESS WIRE)--May 13, 2025--
Susan G. Komen®, the world’s leading breast cancer organization, today released its 2025 Annual Impact Report, highlighting a year of progress made possible by the dedication of its donors, volunteers and partners.
This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20250513335744/en/
Breast cancer is the second leading cause of cancer death among women in the U.S. and is the most common cancer among women worldwide. What’s more, it’s estimated that more than 168,000 people in the U.S. are living with metastatic breast cancer (MBC), also known as stage 4, the most advanced and incurable stage of breast cancer. This year alone, nearly 43,000 people in the U.S. are expected to die from breast cancer — with MBC responsible for most of these deaths.
Komen’s impact report highlights the critical progress made in the fight against breast cancer made possible by the passionate dedication of its donors, volunteers and partners — and the hope for a brighter future driven by its nationwide community. Komen believes that to save lives, the community must focus on conquering aggressive and metastatic breast cancers and eliminating barriers to care to achieve health equity.
To achieve the organization’s goals, to date, Komen has invested nearly $2.5 billion in advocacy, community programs, education and patient support services, ensuring people are educated about the complexities of risk, screening, diagnosis and treatment for breast cancer and have access to the care they need. Komen has also invested nearly $1.1 billion in research making it the largest nonprofit contributor to the cause, second only to the U.S. government. This investment has led to new ways to prevent, detect, diagnose and treat breast cancer.
“Susan G. Komen’s impact is woven into nearly every major breakthrough and patient-centered policy in the history of breast cancer, but we could never have come this far without the support of our community,” said Paula Schneider, Komen president and CEO. “Our donors, volunteers, partners and fundraisers are the heart of our history and frankly, our future. Many come to Komen because they’ve been personally touched by this disease — and, as a breast cancer survivor, myself included. There is power in pain and hope alike, and the progress we’ve made is a testament to those who’ve turned their experience and grief into action.”
Key Highlights from Komen’s 2025 impact report include:
With proposed federal budget cuts for Fiscal Year 2026 threatening to erode decades of progress in the fight against breast cancer, continued funding especially for early detection programs, safety net care services and research has never been more critical. If these cuts proceed, Susan G. Komen will continue to stand as the leading breast cancer organization in the nation — but without sustained government support, lifesaving breakthroughs may be delayed, early detection efforts will be reduced, and patients will be left behind with poor outcomes to follow.
As Komen continues to lead the charge against breast cancer, the 2025 Impact Report serves as both a reflection of what’s been achieved and a call to action for what still needs to be accomplished. Every advancement — whether in research, patient care, education or policy — is fueled by the commitment of those who stand with Komen.
“With continued support, we can build on these incredible milestones to ensure everyone affected by this disease has access to the high-quality care, resources and support they need to survive and thrive after breast cancer,” added Schneider. “The fight is far from over — but together, we will finish it.”
Read the full report online.
About Susan G. Komen ®
Susan G. Komen ® is the world’s leading nonprofit breast cancer organization, working to save lives and end breast cancer forever. Komen has an unmatched, comprehensive 360-degree approach to fighting this disease across all fronts and supporting millions of people in the U.S. and in countries worldwide. We advocate for patients, drive research breakthroughs, improve access to high-quality care, offer direct patient support and empower people with trustworthy information. Founded by Nancy G. Brinker, who promised her sister, Susan G. Komen, that she would end the disease that claimed Suzy’s life, Komen remains committed to supporting those affected by breast cancer today, while tirelessly searching for tomorrow’s cures. Visit komen.org or call 1-877 GO KOMEN. Connect with us on social at www.komen.org/contact-us/follow-us/.
Progress Highlights from Susan G. Komen’s® 2025 Impact Report
DUBAI, United Arab Emirates (AP) — U.S. President Donald Trump said Iran wants to negotiate with Washington after his threat to strike the Islamic Republic over its bloody crackdown on protesters, a move coming as activists said Monday the death toll in the nationwide demonstrations rose to at least 544.
Iran had no immediate reaction to the news, which came after the foreign minister of Oman — long an interlocutor between Washington and Tehran — traveled to Iran this weekend. It also remains unclear just what Iran could promise, particularly as Trump has set strict demands over its nuclear program and its ballistic missile arsenal, which Tehran insists is crucial for its national defense.
Meanwhile Monday, Iran called for pro-government demonstrators to head to the streets in support of the theocracy, a show of force after days of protests directly challenging the rule of 86-year-old Supreme Leader Ayatollah Ali Khamenei. Iranian state television aired chants from the crowd, who shouted “Death to America!” and “Death to Israel!”
Trump and his national security team have been weighing a range of potential responses against Iran including cyberattacks and direct strikes by the U.S. or Israel, according to two people familiar with internal White House discussions who were not authorized to comment publicly and spoke on condition of anonymity.
“The military is looking at it, and we’re looking at some very strong options,” Trump told reporters on Air Force One on Sunday night. Asked about Iran’s threats of retaliation, he said: “If they do that, we will hit them at levels that they’ve never been hit before.”
Trump said that his administration was in talks to set up a meeting with Tehran, but cautioned that he may have to act first as reports of the death toll in Iran mount and the government continues to arrest protesters.
“I think they’re tired of being beat up by the United States,” Trump said. “Iran wants to negotiate.”
He added: “The meeting is being set up, but we may have to act because of what’s happening before the meeting. But a meeting is being set up. Iran called, they want to negotiate.”
Iran through country's parliamentary speaker warned Sunday that the U.S. military and Israel would be “legitimate targets” if America uses force to protect demonstrators.
More than 10,600 people also have been detained over the two weeks of protests, said the U.S.-based Human Rights Activists News Agency, which has been accurate in previous unrest in recent years and gave the death toll. It relies on supporters in Iran crosschecking information. It said 496 of the dead were protesters and 48 were with security forces.
With the internet down in Iran and phone lines cut off, gauging the demonstrations from abroad has grown more difficult. The Associated Press has been unable to independently assess the toll. Iran’s government has not offered overall casualty figures.
Those abroad fear the information blackout is emboldening hard-liners within Iran’s security services to launch a bloody crackdown. Protesters flooded the streets in the country’s capital and its second-largest city on Saturday night into Sunday morning. Online videos purported to show more demonstrations Sunday night into Monday, with a Tehran official acknowledging them in state media.
In Tehran, a witness told the AP that the streets of the capital empty at the sunset call to prayers each night. By the Isha, or nighttime prayer, the streets are deserted.
Part of that stems from the fear of getting caught in the crackdown. Police sent the public a text message that warned: “Given the presence of terrorist groups and armed individuals in some gatherings last night and their plans to cause death, and the firm decision to not tolerate any appeasement and to deal decisively with the rioters, families are strongly advised to take care of their youth and teenagers.”
Another text, which claimed to come from the intelligence arm of the paramilitary Revolutionary Guard, also directly warned people not to take part in demonstrations.
“Dear parents, in view of the enemy’s plan to increase the level of naked violence and the decision to kill people, ... refrain from being on the streets and gathering in places involved in violence, and inform your children about the consequences of cooperating with terrorist mercenaries, which is an example of treason against the country,” the text warned.
The witness spoke to the AP on condition of anonymity due to the ongoing crackdown.
The demonstrations began Dec. 28 over the collapse of the Iranian rial currency, which trades at over 1.4 million to $1, as the country’s economy is squeezed by international sanctions in part levied over its nuclear program. The protests intensified and grew into calls directly challenging Iran’s theocracy.
Nikhinson reported from aboard Air Force One.
In this frame grab from video obtained by the AP outside Iran, a masked demonstrator holds a picture of Iran's Crown Prince Reza Pahlavi during a protest in Tehran, Iran, Friday, January. 9, 2026. (UGC via AP)
In this frame grab from footage circulating on social media from Iran shows protesters taking to the streets despite an intensifying crackdown as the Islamic Republic remains cut off from the rest of the world in Tehran, Iran, Friday, Jan. 9, 2026.(UGC via AP)
In this frame grab from footage circulating on social media from Iran showed protesters once again taking to the streets of Tehran despite an intensifying crackdown as the Islamic Republic remains cut off from the rest of the world in Tehran, Iran, Saturday Jan. 10, 2026. (UGC via AP)
