Iran and the United States held a fifth round of talks in Rome on Friday over Tehran’s rapidly advancing nuclear program.
The negotiations represent a milestone in the fraught relations between the two nations over Iran's program, which is enriching uranium close to weapons-grade levels. Officials are now focused on the details that could make or break any accord.
Here's a timeline of the tensions between the two countries over Iran's atomic program.
1967 — Iran takes possession of its Tehran Research Reactor under America’s “Atoms for Peace” program.
1979 — Shah Mohammad Reza Pahlavi, fatally ill, flees Iran as popular protests against him surge. Ayatollah Ruhollah Khomeini returns to Tehran and the Islamic Revolution sweeps him to power. Students seize the United States Embassy in Tehran, beginning the 444-day hostage crisis. Iran’s nuclear program goes fallow under international pressure.
August 2002 — Western intelligence services and an Iranian opposition group reveal Iran’s secret Natanz nuclear enrichment facility.
June 2003 — Britain, France and Germany engage Iran in nuclear negotiations.
October 2003 — Iran suspends uranium enrichment.
February 2006 — Iran announces it will restart uranium enrichment following the election of hard-line president Mahmoud Ahmadinejad. Britain, France and Germany walk out of stalled negotiations.
June 2009 — Iran’s disputed presidential election sees Ahmadinejad re-elected despite fraud allegations, sparking Green Movement protests and violent government crackdown.
October 2009 — Under President Barack Obama, the U.S. and Iran open a secret backchannel for messages in the sultanate of Oman.
July 2012 — U.S. and Iranian officials hold face-to-face secret talks in Oman.
July 14, 2015 — World powers and Iran announce a long-term, comprehensive nuclear agreement that limits Tehran's enrichment of uranium in exchange for the lifting of economic sanctions.
May 2018 — Trump unilaterally withdraws the U.S. from the nuclear agreement, calling it the “worst deal ever.” He says he’ll get better terms in new negotiations to stop Iran’s missile development and support for regional militias. Those talks don’t happen in his first term.
May 8, 2019 — Iran announces it will begin backing away from the accord. A series of regional attacks on land and at sea blamed on Tehran follow.
Jan. 3, 2020 — A U.S. drone strike in Baghdad kills Gen. Qassem Soleimani, the architect of Tehran’s proxy wars in the Middle East.
Jan. 8, 2020 — In retaliation for Soleimani’s killing, Iran launches a barrage of missiles at military bases in Iraq that are home to thousands of American and Iraqi troops. More than 100 U.S. service members suffer traumatic brain injuries. As Iran braces for a counterattack, the Revolutionary Guard shoots down a Ukrainian passenger plane shortly after takeoff from Tehran’s international airport, reportedly mistaking it for a U.S. cruise missile. All 176 people on board are killed.
July 2020 — A mysterious explosion tears apart a centrifuge production plant at Iran’s Natanz nuclear enrichment facility. Iran blames the attack on archenemy Israel.
April 6, 2021 — Iran and the U.S. under President Joe Biden begin indirect negotiations in Vienna over how to restore the nuclear deal. Those talks, and others between Tehran and European nations, fail to reach any agreement.
April 11, 2021 — A second attack within a year targets Iran’s Natanz nuclear site, again likely carried out by Israel.
April 16, 2021 — Iran begins enriching uranium up to 60% — its highest purity ever and a technical step from weapons-grade levels of 90%.
Feb. 24, 2022 – Russia launches its full-scale invasion of Ukraine. Moscow ultimately will come to rely on Iranian bomb-carrying drones in the conflict, as well as missiles.
July 17, 2022 — An adviser to Iran’s supreme leader, Kamal Kharrazi, says that Iran is technically capable of making a nuclear bomb, but has not decided whether to build one. His remarks will be repeated by others in the coming years as tensions grow.
Oct. 7, 2023 — Hamas militants from the Gaza Strip storm into Israel, killing 1,200 people and taking 250 others hostage. This begins the most intense war ever between Israel and Hamas. Iran, which has armed Hamas, offers support to the militants. Regional tensions spike.
Nov. 19, 2023 — Yemen’s Houthi rebels, long supported by Iran, seize the ship Galaxy Leader, beginning a monthslong campaign of attacks on shipping through the Red Sea corridor that the U.S. Navy describes as the most intense combat it has seen since World War II. The attacks mirror tactics earlier used by Iran.
April 14, 2024 — Iran launches an unprecedented direct attack on Israel, firing over 300 missiles and attack drones. Israel, working with a U.S.-led international coalition, intercepts much of the incoming fire.
April 19, 2024 — A suspected Israeli strike hits an air defense system by an airport in Isfahan, Iran.
July 31, 2024 – Ismail Haniyeh, a Hamas leader, is assassinated apparently by Israel during a visit to Tehran after the inauguration of reformist President Masoud Pezeshkian.
Sept. 27, 2024 — Israeli airstrike kills Hezbollah leader Hassan Nasrallah.
Oct. 1, 2024 — Iran launches its second direct attack on Israel, though a U.S.-led coalition and Israel shoot down most of the missiles.
Oct. 16, 2024 — Israel kills Hamas leader Yahya Sinwar in the Gaza Strip.
Oct. 26, 2024 — Israel openly attacks Iran for the first time, striking air defense systems and sites associated with its missile program.
Jan. 20, 2025 — Trump is inaugurated for his second term as president.
Feb. 7, 2025 – Iran's Supreme Leader Ayatollah Ali Khamenei says proposed talks with the U.S. are “not intelligent, wise or honorable.”
March 7, 2025 – Trump says he sent a letter to Khamenei seeking a new nuclear deal with Tehran.
March 15, 2025 — Trump launches intense airstrikes targeting Houthi rebels in Yemen, the last members of Iran's self-described “Axis of Resistance” capable of daily attacks.
April 7, 2025 — Trump announces the U.S. and Iran will hold direct talks in Oman. Iran says they'll be indirect talks, but confirms the meeting.
April 12, 2025 — First round of talks between Iran and the U.S. take place in Oman, ending with a promise to hold more talks after U.S. Mideast envoy Steve Witkoff and Iranian Foreign Minister Abbas Araghchi “briefly spoke” together.
April 19, 2025 — Second round of talks between the U.S. and Iran are held in Rome.
April 26, 2025 — Iran and the U.S. meet in Oman a third time, but the negotiations include talks at the expert level for the first time.
May 11, 2025 — Iran and the U.S. meet in Oman for a fourth round of negotiations ahead of Trump's trip to the Mideast.
May 23, 2025 — Iran and the U.S. meet in Rome for a fifth round of talks, with Oman saying the negotiations made "some but not conclusive progress."
In this photo released by the official website of the office of the Iranian supreme leader, Supreme Leader Ayatollah Ali Khamenei speaks during a memorial in Tehran, Iran, Tuesday, May 20, 2025 for late President Ebrahim Raisi, who died in a helicopter crash last year. (Office of the Iranian Supreme Leader via AP)
CRANS-MONTANA, Switzerland (AP) — About 40 people were killed and another 115 injured, most of them seriously, after a fire ripped through a bar’s New Year celebration in a Swiss Alpine resort less than two hours after midnight Thursday, police said.
Authorities did not immediately have an exact count of the deceased.
The Crans-Montana resort is best known as an international ski and golf venue, and overnight, its crowded Le Constellation bar morphed from a scene of revelry into the site of one of Switzerland’s worst tragedies.
Valais Canton police commander Frédéric Gisler said during a news conference that work is underway to identify the victims and inform their families, adding that the community is “devastated.”
Thirteen of the wounded were Italian citizens, and another six Italians are unaccounted for, Italy’s ambassador to Switzerland, Gian Lorenzo Cornado, told state-run RAI television.
Beatrice Pilloud, Valais Canton attorney general, said it was too early to determine the cause of the fire. Experts have not yet been able to go inside the wreckage.
“At no moment is there a question of any kind of attack,” Pilloud said.
She later said the number of people who were in the bar is “currently totally unknown,” adding that its maximum capacity will be part of the investigation.
“For the time being, we don’t have any suspect,” she added, when asked if anyone had been arrested over the fire. “An investigation has been opened, not against anyone, but to illuminate the circumstances of this dramatic fire.”
Gisler said the priority until further notice would be identifying the victims, and added that “this work will have to take several days.”
Axel Clavier, a 16-year-old from Paris who survived the blaze, described “total chaos” inside the bar. One of his friends died and “two or three" were missing, he told The Associated Press.
He said he hadn’t seen the fire start, but did see waitresses arrive with Champagne bottles with sparklers, he said.
Clavier said he felt like he was suffocating and initially hid behind a table, then ran upstairs and tried to use a table to break a Plexiglas window. It fell out of its casing, allowing him to escape.
He lost his jacket, shoes, phone and bank card while fleeing, but “I am still alive and it’s just stuff.”
“I’m still in shock,” he added.
Two women told French broadcaster BFMTV they were inside when they saw a male bartender lifting a female bartender on his shoulders as she held a lit candle in a bottle. The flames spread, collapsing the wooden ceiling, they told the broadcaster.
One of the women described a crowd surge as people frantically tried to escape from a basement nightclub up a narrow flight of stairs and through a narrow door.
Another witness speaking to BFMTV described people smashing windows to escape the blaze, some gravely injured, and panicked parents rushing to the scene in cars to see whether their children were trapped inside. The young man said he saw about 20 people scrambling to get out of the smoke and flames and likened what he saw to a horror movie as he watched from across the street.
One of the people unaccounted for was an Italian, Giovanni Tamburi, whose mother Carla Masielli issued an appeal for any news about her son and asked the media to show his photo in hopes of identifying him, according to RAI.
“We have called all the hospitals but they don’t give me any news. We don’t know if he’s among the dead. We don’t know if he’s among the missing,” she wailed. “They don’t tell us anything!”
The injured were so numerous that the intensive care unit and operating theater at the regional hospital quickly hit full capacity, said Mathias Reynard, head of the regional government of the Valais Canton.
“This evening should have been a moment of celebration and coming together, but it turned into a nightmare,” said Reynard.
Italian Foreign Minister Antonio Tajani was planning to go to the site on Friday given the significant number of Italians involved.
Three of the wounded were being transported from the Sion hospital in Switzerland to Milan’s Niguarda, the Italian civil protection agency said.
In a region busy with tourists skiing on the slopes, the authorities have called on the local population to show caution in the coming days to avoid any accidents that could require medical resources that are already overwhelmed.
With high-altitude ski runs rising around 3,000 meters (nearly 9,850 feet) in the heart of the Valais region's snowy peaks and pine forests, Crans-Montana is one of the top venues on the World Cup circuit. The resort will host the best men’s and women’s downhill racers, including Lindsey Vonn, for their final events before the Milan-Cortina Olympics in February. The town's Crans-sur-Sierre golf club stages the European Masters each August on a picturesque course.
The Swiss blaze on Thursday came 25 years after an inferno in the Dutch fishing town of Volendam on New Year’s Eve, which killed 14 people and injured more than 200 as they celebrated in a cafe.
Swiss President Guy Parmelin, speaking on his first day in office, said many emergency staff had been “confronted by scenes of indescribable violence and distress.”
“This Thursday must be the time of prayer, unity and dignity,” he said. “Switzerland is a strong country not because it is sheltered from drama, but because it knows how to face them with courage and a spirit of mutual help.”
Dazio reported from Berlin and Leicester reported from Paris. Geir Moulson in Berlin and Graham Dunbar in Geneva contributed to this report.
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This story has been corrected to fix the spelling of the name of Mathias Reynard, head of the regional government of the Valais Canton.
A floral tribute left near the area where a fire broke out at the Le Constellation bar and lounge during New Year's celebration, in Crans-Montana, Switzerland, Thursday, Jan. 1, 2026. (Jean-Christophe Bott/Keystone via AP)
A hearse car drives as police officers inspect the area where a fire broke out at the Le Constellation bar and lounge during New Year's celebration, in Crans-Montana, Switzerland, Thursday, Jan. 1, 2026. (Jean-Christophe Bott/Keystone via AP)
Police officers inspect the area where a fire broke out at the Le Constellation bar and lounge leaving people dead and injured, during New Year’s celebration, in Crans-Montana, Swiss Alps, Switzerland, Thursday, Jan. 1, 2026. (Jean-Christophe Bott/Keystone via AP)
Police officers inspect the area where a fire broke out at the Le Constellation bar and lounge leaving people dead and injured, during New Year’s celebration, in Crans-Montana, Swiss Alps, Switzerland, Thursday, Jan. 1, 2026. (Jean-Christophe Bott/Keystone via AP)
From left, Mathias Reynard, State Councillor and president of the Council of State of the Canton of Valais, Stephane Ganzer, State Councillor and head of the Department of Security, Institutions and Sport of the Canton of Valais, Frederic Gisler, Commander of the Valais Cantonal Police and Beatrice Pilloud, Attorney General of the Canton of Valais during a press conference in Lens, following a fire that broke out at the Le Constellation bar and lounge leaving people dead and injured, during New Year’s celebration, in Crans-Montana, Swiss Alps, Switzerland, Thursday, Jan. 1, 2026. (Alessandro della Valle/Keystone via AP)
Police officers inspect the area where a fire broke out at the Le Constellation bar and lounge leaving people dead and injured, during New Year’s celebration, in Crans-Montana, Swiss Alps, Switzerland, Thursday, Jan. 1, 2026. (Jean-Christophe Bott/Keystone via AP)
From left, Mathias Reynard, State Councillor and president of the Council of State of the Canton of Valais, Stephane Ganzer, State Councillor and head of the Department of Security, Institutions and Sport of the Canton of Valais, Frederic Gisler, Commander of the Valais Cantonal Police, Beatrice Pilloud, Attorney General of the Canton of Valais and Nicole Bonvin-Clivaz, Vice-President of the Municipal Council of Crans-Montana during a press conference in Lens, following a fire that broke out at the Le Constellation bar and lounge leaving people dead and injured, during New Year’s celebration, in Crans-Montana, Swiss Alps, Switzerland, Thursday, Jan. 1, 2026. (Alessandro della Valle/Keystone via AP)
A skier walks in the area where a fire broke out at the Le Constellation bar and lounge leaving people dead and injured, during New Year’s celebration, in Crans-Montana, Swiss Alps, Switzerland, Thursday, Jan. 1, 2026. (Alessandro della Valle/Keystone via AP)
A banner stating that fireworks are prohibited due to the risk of fire is pictured near the area where a fire broke out at the Le Constellation bar and lounge leaving people dead and injured, during New Year’s celebration, in Crans-Montana, Swiss Alps, Switzerland, Thursday, Jan. 1, 2026. (Alessandro della Valle/Keystone via AP)
Police officers inspect the area where a fire broke out at the Le Constellation bar and lounge leaving people dead and injured, during New Year’s celebration, in Crans-Montana, Swiss Alps, Switzerland, Thursday, Jan. 1, 2026. (Alessandro della Valle/Keystone via AP)
Police officers inspect the area where a fire broke out at the Le Constellation bar and lounge leaving people dead and injured, during New Year’s celebration, in Crans-Montana, Swiss Alps, Switzerland, Thursday, Jan. 1, 2026. (Alessandro della Valle/Keystone via AP)
Police officers inspect the area where a fire broke out at the Le Constellation bar and lounge leaving people dead and injured, during New Year’s celebration, in Crans-Montana, Swiss Alps, Switzerland, Thursday, Jan. 1, 2026. (Alessandro della Valle/Keystone via AP)
Police officers inspect the area where a fire broke out at the Le Constellation bar and lounge leaving people dead and injured, during New Year’s celebration, in Crans-Montana, Swiss Alps, Switzerland, Thursday, Jan. 1, 2026. (Alessandro della Valle/Keystone via AP)
