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SINGAPORE, June 6, 2025 /PRNewswire/ -- Leading international travel service provider Trip.com has announced two new strategic partnerships aimed at expanding its Attractions & Tours business across Southeast Asia. It has signed agreements with Vietnam's premier entertainment brand, Sun World Holding, and Singapore-based DreamUs International Holdings, operator of popular family attractions including the newly-revamped SuperPark Singapore.
These collaborations underscore Trip.com Group's commitment to enhancing user experiences through curated, high-quality travel products and to supporting partners in digital transformation and global outreach.
Strengthening Regional Presence Through Key Partnerships
In Vietnam, Trip.com entered into a strategic partnership with Sun World Holding, a flagship brand under Sun Group. The signing took place on the sidelines of Trip.com Group's Envision 2025 Global Conference in Shanghai. Through this collaboration, Trip.com will distribute Sun World's attraction tickets across domestic and international markets, with a focus on key inbound regions such as South Korea, China, Thailand, and Singapore. The partnership will also support joint marketing initiatives to promote iconic destinations like Phu Quoc, Da Nang, and Sa Pa.
"Vietnam is a key market for Trip.com as we continue to grow internationally, and we are delighted to embark on a new phase of our cooperation with Sun World Holding to strengthen our offerings in this wonderful country," said Mr Chase Liu, General Manager of Attractions & Tours, Trip.com Group. "Together, we aim to promote Vietnam as a premier travel destination and deliver unforgettable experiences to our users worldwide."
Ms Christine Tran, Deputy CEO of Sun World Holding, added: "We are honoured to establish a strategic partnership with Trip.com, one of the leading online travel platforms in the region and the world. With Trip.com's influence, we hope not only to enhance service quality for our customers through technological solutions and optimised distribution systems to Sun World parks but also to strengthen the presence of Sun Hospitality & Entertainment's ecosystem in key international markets, especially in Asia."
In Singapore, Trip.com signed an exclusive ticket distribution agreement with DreamUs International Holdings, the operator of SuperPark Singapore, Pororo Park Singapore, and Tayo Station. Under this agreement, Trip.com will serve as the exclusive authorised third-party distributor for tickets to these attractions, streamlining inventory management and improving access for regional audiences. While DreamUs will continue to operate its direct-to-consumer sales through its official website and on-site counters, all other online platforms and resellers must now source their ticket inventory exclusively via Trip.com or its designated partners.
"This partnership strengthens Trip.com's leadership in the attractions and experiences space," added Mr Liu. "We're proud to support DreamUs in expanding their audience reach while consolidating distribution through our ecosystem."
Ms Carolyn Chia, General Manager of DreamUs International Holdings, commented: "We are excited to collaborate with Trip.com as our exclusive distribution gateway. This partnership allows us to consolidate supply management while reaching new customer segments, both locally and regionally."
Continued Growth in Southeast Asia
These partnerships reflect Trip.com's ongoing investment in Southeast Asia's travel ecosystem. Through innovative collaborations with trusted local brands, the Group continues to expand its one-stop platform capabilities, offering travellers enhanced access to regional experiences and ensuring partners benefit from scalable digital distribution.
Trip.com's Attractions & Tours business in Southeast Asia has expanded rapidly, doubling (over 110% increase) its year-on-year GMV growth last year. Vietnam in particular saw even stronger growth, with 2024's GMV more than tripling (over 250% increase) compared to the previous year, while the slightly more mature Singapore market saw healthy growth of over 80%.
About Trip.com
Trip.com is an international one-stop travel service provider, available in 24 languages across 39 countries and regions in 35 local currencies. Trip.com has an extensive hotel and flight network consisting of more than 1.5 million hotels and flights from over 640 airlines covering 3,400 airports in 220 countries and regions around the globe. Trip.com's world-class 24/7 multilingual customer service, as well as additional centres in Edinburgh, Tokyo and Seoul, help to 'create the best travel experience' for its millions of customers worldwide. To book your next trip, visit trip.com.
About Sun World Holding LLC
Sun World Holding LLC., part of Sun Group, is positioned as a world-class entertainment and hospitality brand. The Sun World system includes nine amusement parks and tourist destinations across Vietnam: Sun World Ba Na Hills, Da Nang Downtown, Sun World Fansipan Legend, Sun World Ha Long, Sun World Hon Thom, Sun World Ba Den Mountain, Sun World Ha Nam, Sun World Cat Ba, and Sun World Sam Son. Each Sun World offers a unique version, showcasing the cultural, human, and natural beauty of each region, telling the story of the destination with a range of fascinating experiences. The Sun Hospitality Group encompasses 15 world-class resorts in Vietnam, many of which have received continuous international accolades, such as InterContinental Danang Sun Peninsula Resort, JW Marriott Phu Quoc Emerald Bay, and Capella Hanoi.
About DreamUs Group
DreamUs Group is a leading provider of experience-based family entertainment with a mission to bring serious happiness to children and families through the power of purposeful play. Headquartered in Singapore, DreamUs Group operates a network of immersive play destinations designed to inspire creativity, build confidence, and foster connection.
With flagship locations in Singapore and Indonesia, our portfolio includes SuperPark Singapore, Pororo Park Singapore, Tayo Station, SuperPark Indonesia (Pondok Indah Mall and Puri Indah Mall), and Pororo Park Indonesia. DreamUs playgrounds offer more than fun—they provide meaningful, developmentally rich experiences that support natural learning through play.
For more information, visit dreamusgroup.com.
SINGAPORE, June 6, 2025 /PRNewswire/ -- Leading international travel service provider Trip.com has announced two new strategic partnerships aimed at expanding its Attractions & Tours business across Southeast Asia. It has signed agreements with Vietnam's premier entertainment brand, Sun World Holding, and Singapore-based DreamUs International Holdings, operator of popular family attractions including the newly-revamped SuperPark Singapore.
These collaborations underscore Trip.com Group's commitment to enhancing user experiences through curated, high-quality travel products and to supporting partners in digital transformation and global outreach.
Strengthening Regional Presence Through Key Partnerships
In Vietnam, Trip.com entered into a strategic partnership with Sun World Holding, a flagship brand under Sun Group. The signing took place on the sidelines of Trip.com Group's Envision 2025 Global Conference in Shanghai. Through this collaboration, Trip.com will distribute Sun World's attraction tickets across domestic and international markets, with a focus on key inbound regions such as South Korea, China, Thailand, and Singapore. The partnership will also support joint marketing initiatives to promote iconic destinations like Phu Quoc, Da Nang, and Sa Pa.
"Vietnam is a key market for Trip.com as we continue to grow internationally, and we are delighted to embark on a new phase of our cooperation with Sun World Holding to strengthen our offerings in this wonderful country," said Mr Chase Liu, General Manager of Attractions & Tours, Trip.com Group. "Together, we aim to promote Vietnam as a premier travel destination and deliver unforgettable experiences to our users worldwide."
Ms Christine Tran, Deputy CEO of Sun World Holding, added: "We are honoured to establish a strategic partnership with Trip.com, one of the leading online travel platforms in the region and the world. With Trip.com's influence, we hope not only to enhance service quality for our customers through technological solutions and optimised distribution systems to Sun World parks but also to strengthen the presence of Sun Hospitality & Entertainment's ecosystem in key international markets, especially in Asia."
In Singapore, Trip.com signed an exclusive ticket distribution agreement with DreamUs International Holdings, the operator of SuperPark Singapore, Pororo Park Singapore, and Tayo Station. Under this agreement, Trip.com will serve as the exclusive authorised third-party distributor for tickets to these attractions, streamlining inventory management and improving access for regional audiences. While DreamUs will continue to operate its direct-to-consumer sales through its official website and on-site counters, all other online platforms and resellers must now source their ticket inventory exclusively via Trip.com or its designated partners.
"This partnership strengthens Trip.com's leadership in the attractions and experiences space," added Mr Liu. "We're proud to support DreamUs in expanding their audience reach while consolidating distribution through our ecosystem."
Ms Carolyn Chia, General Manager of DreamUs International Holdings, commented: "We are excited to collaborate with Trip.com as our exclusive distribution gateway. This partnership allows us to consolidate supply management while reaching new customer segments, both locally and regionally."
Continued Growth in Southeast Asia
These partnerships reflect Trip.com's ongoing investment in Southeast Asia's travel ecosystem. Through innovative collaborations with trusted local brands, the Group continues to expand its one-stop platform capabilities, offering travellers enhanced access to regional experiences and ensuring partners benefit from scalable digital distribution.
Trip.com's Attractions & Tours business in Southeast Asia has expanded rapidly, doubling (over 110% increase) its year-on-year GMV growth last year. Vietnam in particular saw even stronger growth, with 2024's GMV more than tripling (over 250% increase) compared to the previous year, while the slightly more mature Singapore market saw healthy growth of over 80%.
About Trip.com
Trip.com is an international one-stop travel service provider, available in 24 languages across 39 countries and regions in 35 local currencies. Trip.com has an extensive hotel and flight network consisting of more than 1.5 million hotels and flights from over 640 airlines covering 3,400 airports in 220 countries and regions around the globe. Trip.com's world-class 24/7 multilingual customer service, as well as additional centres in Edinburgh, Tokyo and Seoul, help to 'create the best travel experience' for its millions of customers worldwide. To book your next trip, visit trip.com.
About Sun World Holding LLC
Sun World Holding LLC., part of Sun Group, is positioned as a world-class entertainment and hospitality brand. The Sun World system includes nine amusement parks and tourist destinations across Vietnam: Sun World Ba Na Hills, Da Nang Downtown, Sun World Fansipan Legend, Sun World Ha Long, Sun World Hon Thom, Sun World Ba Den Mountain, Sun World Ha Nam, Sun World Cat Ba, and Sun World Sam Son. Each Sun World offers a unique version, showcasing the cultural, human, and natural beauty of each region, telling the story of the destination with a range of fascinating experiences. The Sun Hospitality Group encompasses 15 world-class resorts in Vietnam, many of which have received continuous international accolades, such as InterContinental Danang Sun Peninsula Resort, JW Marriott Phu Quoc Emerald Bay, and Capella Hanoi.
About DreamUs Group
DreamUs Group is a leading provider of experience-based family entertainment with a mission to bring serious happiness to children and families through the power of purposeful play. Headquartered in Singapore, DreamUs Group operates a network of immersive play destinations designed to inspire creativity, build confidence, and foster connection.
With flagship locations in Singapore and Indonesia, our portfolio includes SuperPark Singapore, Pororo Park Singapore, Tayo Station, SuperPark Indonesia (Pondok Indah Mall and Puri Indah Mall), and Pororo Park Indonesia. DreamUs playgrounds offer more than fun—they provide meaningful, developmentally rich experiences that support natural learning through play.
For more information, visit dreamusgroup.com.
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Trip.com Strengthens Southeast Asia Footprint with Strategic Partnerships in Vietnam and Singapore
Trip.com Strengthens Southeast Asia Footprint with Strategic Partnerships in Vietnam and Singapore
Trip.com Strengthens Southeast Asia Footprint with Strategic Partnerships in Vietnam and Singapore
Highlights:
- Neurizon announces an expansion to the size of Regimen I intended to support a larger and more informative dataset, with accelerated time to topline readout and no change in funding requirements
- Increase in sample size driven by enrolment rate exceeding original expectations and the absence of a concurrent regimen during the expected recruitment period
- Regimen I expands from 160 to 240 participants to maintain statistical power for the primary endpoint aligned with the original trial assumptions
- The increased sample size allows more robust analysis of subgroups and biomarkers and ensures a fully powered study at topline results
- Based on current enrolment momentum, Neurizon anticipates that last participant dosing will now occur in Q2 CY2027 with topline results to be released early Q3 CY2027, exceeding previous trial timeframe projection
- Expanded participant cohort cost is materially offset by a contribution of philanthropic funds from the Sean M. Healey & AMG Center for ALS at Mass General Brigham
- As a result of diligent cost management and rapid recruitment, this change is expected to have no impact on Neurizon's costs through to topline results and only a very modest increase in the total cost of completing the full trial
- Larger, consistent dataset expected to strengthen partnering and commercial positioning for NUZ-001
- 113 participants assigned and 74 dosed as of 22 May 2026, with 64 US clinical trial sites activated and 193 participants screened under the master protocol to date
- Neurizon to host a shareholder webinar on 28 May to discuss the trial recruitment expansion in further detail
MELBOURNE, Australia, May 27, 2026 /PRNewswire/ -- Neurizon® Therapeutics Limited (ASX: NUZ & NUZOA; OTCQB: NUZTF) ("Neurizon" or "the Company"), a clinical-stage biotech company dedicated to advancing innovative treatments for neurodegenerative diseases, is pleased to advise that Regimen I of the HEALEY ALS Platform Trial will increase its total patient cohort from 160 to 240 participants. The expansion is driven by the enrolment rate exceeding original expectations and the absence of a concurrent regimen during the expected recruitment period. Expanded design maintains statistical power for the primary endpoint aligned with the original assumptions underpinning the study and allows more robust analysis of subgroups and biomarkers.
Importantly, the current recruitment momentum is expected to accelerate the overall trial timeline relative to previous expectations, despite the increased recruitment target. Based on current trends, the Company now anticipates last participant dosing in Q2 CY2027, with topline results expected in early Q3 CY2027.
Following an extensive review of the scientific, statistical, financial and regulatory considerations, as well as ongoing engagement with the Sean M. Healey & AMG Center, Regimen I will now comprise 180 NUZ-001 participants and 60 Regimen I placebo controls.
As of 22 May 2026, 113 participants have been assigned to Regimen I and 74 participants have been dosed. There are 64 clinical trial sites activated across the United States and 193 participants have been screened to date under the master protocol. While current recruitment momentum continues to track ahead of prior expectations, future recruitment rates may vary over time.
Based on the expanded 240-patient design, accelerated enrolment timelines and a meaningful financial contribution of philanthropic funds from the Sean M. Healey & AMG Center for ALS at Mass General Brigham, Neurizon expects the total funding requirements through to study completion to remain unchanged.
Neurizon remains focused on efficiently delivering a scientifically meaningful outcome from the HEALEY ALS Platform Trial. The expansion of the trial has no impact on Neurizon's expected costs through to topline results, with only a modest overall increase in the total cost of completing the full trial. This increase is expected to be further offset through eligibility under the Australian Federal Government's R&D Tax Incentive Program, together with the financial contribution of philanthropic funds from the Sean M. Healey & AMG Center for ALS at Mass General Brigham. This demonstrates Neurizon's continued focus on cost and capital efficiency and ensures the Company remains fully funded through completion of the trial.
Neurizon believes expanding the regimen is a fiscally disciplined and strategically attractive decision to generate a larger, more statistically robust, and internally consistent ALS dataset, which eliminates reliance on placebo groups from other regimens and maintains the original statistical assumptions underpinning the study at topline results.
Interim Executive Chairman, Mr Sergio Duchini said: "The expansion of Regimen I to 240 participants reflects our considerable confidence in NUZ-001 and is underpinned by strong momentum being delivered across the HEALEY ALS Platform Trial study. Importantly, this decision maintains the statistical power for the analysis of the primary endpoint and the potential for topline results ahead of our previously stated schedule."
"The strength of recruitment and engagement across the HEALEY ALS Platform Trial network has positioned Neurizon to proactively optimise the study design at an important point in the trial. We believe the expanded dataset will strengthen the statistical robustness, interpretability and strategic value of the program as we advance toward topline results."
"Importantly, the larger and more internally consistent dataset is expected to enhance future regulatory, partnering and commercial opportunities for NUZ-001, while also strengthening our ability to generate valuable biomarker and translational insights relevant to the broader neurodegenerative disease landscape."
"ALS remains an area of urgent unmet medical need, and we believe this decision further strengthens Neurizon's positioning as we continue advancing NUZ-001 through late-stage clinical development."
Merit Cudkowicz, MD, MSc, Director of the Healey & AMG Center and Executive Director of the Mass General Brigham Neuroscience Institute, said: "This partnership with Neurizon reflects a shared commitment to advancing meaningful science while keeping people living with ALS at the center of everything we do. We thank our patient advisory committee members and the entire ALS community for active participation in this important clinical trial. By working collaboratively, we can accelerate progress, strengthen the research ecosystem, and ultimately deliver solutions that better serve the ALS community."
Sabrina Paganoni, MD, PhD, Co-Principal Investigator of the HEALEY ALS Platform Trial and Co-Director of the Neurological Clinical Research Institute (NCRI) said: "I want to sincerely thank the Network of Excellence for ALS (NEALS) investigators and site teams for achieving our most rapid enrollment to date — an extraordinary milestone that reflects their dedication and collaboration. I also want to recognize the coordination center at the Healey & AMG Center and key vendors for outstanding implementation and execution of the study, which made this success possible, as well as participants and their families for their dedication and support."
About the HEALEY ALS Platform Trial:
The HEALEY ALS Platform Trial (ClinicalTrials.gov identifier: NCT04297683) is a multicentre, double-blind, placebo controlled adaptive Phase 2/3 clinical trial conducted by the Sean M. Healey & AMG Center for ALS at Mass General Brigham in the United States (US), created in partnership with the Network of Excellence for ALS (NEALS). Entry into the HEALEY ALS Platform Trial is competitive, with drug candidates reviewed and selected by expert committees based on scientific merit and evidence of potential benefit in ALS. The goal of the HEALEY ALS Platform Trial is to accelerate the development of potential new ALS therapies.
This announcement has been authorised for release by the Board of Neurizon Therapeutics Limited.
About Neurizon Therapeutics Limited
Neurizon Therapeutics Limited (ASX: NUZ) is a clinical-stage biotechnology company dedicated to advancing treatments for neurodegenerative diseases. Neurizon is developing its lead drug candidate, NUZ-001, for the treatment of ALS, which is the most common form of motor neurone disease. Neurizon's strategy is to accelerate access to effective ALS treatments for patients while exploring the potential of NUZ-001 for broader neurodegenerative applications. Through international collaborations and rigorous clinical programs, Neurizon is dedicated to creating new horizons for patients and families impacted by complex neural disorders. NUZ-001 is an investigational product and is not approved for commercial use in any jurisdiction.
Neurizon® is a registered trademark of Neurizon Therapeutics Limited
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HEALEY ALS Platform Trial Regimen I expands to 240 participants
