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Agilent and National Heart Centre Singapore Sign Agreement to Advance Metabolic Heart Failure Research

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Agilent and National Heart Centre Singapore Sign Agreement to Advance Metabolic Heart Failure Research
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Agilent and National Heart Centre Singapore Sign Agreement to Advance Metabolic Heart Failure Research

2025-11-13 12:05 Last Updated At:12:25

Research focuses on human cardiac organoids to uncover metabolic drivers of heart failure and accelerate new therapeutic strategies to improve cardiovascular outcomes

SINGAPORE, Nov. 13, 2025 /PRNewswire/ -- Agilent Technologies Inc. (NYSE: A) announced the signing of a five-year Memorandum of Understanding (MOU) with National Heart Centre Singapore (NHCS) to accelerate innovation in metabolic heart failure research, one of the most complex and underserved areas in cardiovascular medicine.

Agilent Seahorse XF Flex Analyzer 3D Workflow Features Metabolic Profile that Serves as Dynamic Biomarkers of Cell Health jwplayer('myplayer1').setup({file: 'https://mma.prnasia.com/media2/2820817/Seahorse_XF_Flex_3D_Workflow_and_Applications_Video_Agilent.mp4', image: 'https://mma.prnasia.com/media2/2820817/Seahorse_XF_Flex_3D_Workflow_and_Applications_Video_Agilent.mp4?p=medium', autostart:'false', stretching : 'uniform', width: '512', height: '288'});

Heart failure remains a leading global cause of death and disability¹, with metabolic forms such as diabetic heart failure and heart failure with preserved ejection fraction (HFpEF) posing challenges due to limited treatment options². Under this agreement, Agilent and NHCS will combine their expertise in human cardiac organoids using human-derived heart tissues with cutting-edge analytical technologies, including Agilent's latest Seahorse XF Flex Analyzer which expands real-time metabolic analysis into 3D tissues and organoid workflows to investigate metabolic drivers of heart failure.

"Our collaboration with Agilent allows us to advance the study of heart disease using patient-specific beating heart cells. By combining NHCS's expertise with Agilent's advanced technology, we can detect the earliest changes in how heart cells use energy before visible damage occurs. This accelerates the discovery of new therapies and safely testing them, ultimately offering hope to heart failure patients who currently have limited treatment options," said Prof Derek Hausenloy, director of the National Heart Research Institute Singapore (NHRIS) at NHCS.

NHCS has established itself as a leader in modelling monogenic cardiac diseases using patient-specific induced pluripotent stem cells (iPSCs), which led to novel therapeutic targets now undergoing clinical evaluation³,⁴. Building on this foundation, the integration of Agilent's next-generation technology and NHCS's Preclinical Platform for Development of Therapeutics for Heart Failure (PREVENT-HF) positions the collaboration to provide hypotheses for clinical validation, offering new insights into disease progression, novel therapeutic development, and assessment of treatment safety and efficacy in clinically relevant models.

"Together with NHCS, we are bridging science and technology to reimagine how metabolic heart failure is understood and treated through translational research. This partnership reflects our shared commitment to addressing the unmet needs in cardiovascular care while strengthening our leadership in the biomedical ecosystem, positioning us at the frontier of cardiovascular research locally, regionally, and globally." Said Bharat Bhardwaj, vice president of APAC sales at Agilent.

Over the past decade, Agilent has made significant contributions to research advancement aimed at improving population health in Singapore. In 2019, the National University of Singapore (NUS), National University Hospital (NUH), and Agilent launched a $38 million research hub to boost clinical diagnostics and biochemistry testing.

Last year, Agilent partnered with NUS, acting through the Yong Loo Lin School of Medicine (NUS Medicine), established the NUS-Agilent Center of Excellence in Cell Metabolism in support of the Singapore Ministry of Health's Project RESET, Cardiovascular Metabolic Disease Translational Research Programme (CVMD-TRP) and PREVENT-HF to accelerate the discovery of novel insights into the complex mechanisms of heart disease.

About Agilent Technologies

Agilent Technologies Inc. (NYSE: A) is a global leader in analytical and clinical laboratory technologies, delivering insights and innovation that help our customers bring great science to life. Agilent's full range of solutions includes instruments, software, services, and expertise that provide trusted answers to our customers' most challenging questions. The company generated revenue of $6.51 billion in fiscal year 2024 and employs approximately 18,000 people worldwide. Information about Agilent is available at www.agilent.com. To receive the latest Agilent news, subscribe to the Agilent Newsroom. Follow Agilent on LinkedIn and Facebook.

About the National Heart Centre Singapore

The National Heart Centre Singapore (NHCS) is a leading national and regional referral centre for cardiovascular diseases, offering 185 beds and a comprehensive range of cardiac care services from preventive to rehabilitative. Ranked #12 as the World's Best Cardiology Hospital by Newsweek 2025, NHCS's clinical outcomes are consistently recognized at the international level, meeting or exceeding global standards. It is also the only facility in Singapore providing heart and lung transplantation programme.

As an academic medical centre, NHCS is committed to training healthcare professionals and advancing cardiovascular health through cutting-edge translational research in collaboration with local and international collaborators.

For more information, please visit: www.nhcs.com.sg

Media Contacts

Grace Thong

Agilent Technologies 

+65 9688 2152

grace.thong@agilent.com

 

Belinda Lim

National Heart Centre Singapore

+65 9689 7453

Belinda.lim.s.m@nhcs.com.sg

Grace Thong

Agilent Technologies 

+65 9688 2152

grace.thong@agilent.com

 

Belinda Lim

National Heart Centre Singapore

+65 9689 7453

Belinda.lim.s.m@nhcs.com.sg

 

1 https://www.who.int/health-topics/cardiovascular-diseases#tab=tab_1 

2 Ramachandra, C. J. A., Hernandez-Resendiz, S., Crespo-Avilan, G. E., Lin, Y. H. & Hausenloy, D. J. Mitochondria in acute myocardial infarction and cardioprotection. EBioMedicine 57, 102884, doi:10.1016/j.ebiom.2020.102884 (2020).

3 Mehta, A. et al. Identification of a targeted and testable antiarrhythmic therapy for long-QT syndrome type 2 using a patient-specific cellular model. European heart journal 39, 1446-1455, doi:10.1093/eurheartj/ehx394 (2018).

4 Ramachandra, C. J. A. et al. Inhibiting cardiac myeloperoxidase alleviates the relaxation defect in hypertrophic cardiomyocytes. Cardiovascular research 118, 517-530, doi:10.1093/cvr/cvab077 (2022).

1 https://www.who.int/health-topics/cardiovascular-diseases#tab=tab_1 

2 Ramachandra, C. J. A., Hernandez-Resendiz, S., Crespo-Avilan, G. E., Lin, Y. H. & Hausenloy, D. J. Mitochondria in acute myocardial infarction and cardioprotection. EBioMedicine 57, 102884, doi:10.1016/j.ebiom.2020.102884 (2020).

3 Mehta, A. et al. Identification of a targeted and testable antiarrhythmic therapy for long-QT syndrome type 2 using a patient-specific cellular model. European heart journal 39, 1446-1455, doi:10.1093/eurheartj/ehx394 (2018).

4 Ramachandra, C. J. A. et al. Inhibiting cardiac myeloperoxidase alleviates the relaxation defect in hypertrophic cardiomyocytes. Cardiovascular research 118, 517-530, doi:10.1093/cvr/cvab077 (2022).

 

** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **

Agilent and National Heart Centre Singapore Sign Agreement to Advance Metabolic Heart Failure Research

Agilent and National Heart Centre Singapore Sign Agreement to Advance Metabolic Heart Failure Research

VICTORIA, Seychelles, April 1, 2026 /PRNewswire/ -- Global crypto trading platform BYDFi will mark its 6th anniversary with a month-long celebration beginning on April 1, 2026, highlighting BYDFi's evolution into an all-in-one crypto trading platform built on a CEX + DEX dual-engine model. Over six years, BYDFi has strengthened infrastructure, user safeguards, and market access, reinforcing an operating foundation built for reliability.

A Month-Long Celebration for BYDFi's 6th Anniversary

Beginning on April 1, 2026, BYDFi's anniversary program will feature rewards of more than $1,000,000 USDT.

BYDFi's anniversary campaign will center on three major events: Warm-Up Tasks, covering onboarding, first trades, fiat purchase rewards, referrals, and community participation; Shoot to Win, a football-themed lucky-draw experience; and the Futures Golden Ball Cup, a two-round futures trading competition.

Together, these three events give both new and existing users more ways to join BYDFi's 6th anniversary while reflecting BYDFi's broader journey over the past six years.

For more event details, please visit the official website: BYDFi 6th Anniversary.

BYDFi's Evolution: From Core Trading to Broader Market Access

Over the past six years, BYDFi has grown into a global crypto trading platform serving more than 1 million users across 190+ countries and regions. Since launch, BYDFi has broadened product offerings, strengthened user safeguards, and expanded across both centralized and onchain trading.

Recent milestones shaped BYDFi's growth:

  • July 2025: BYDFi supported tokenized U.S. equities through xStocks.
  • August 2025: BYDFi entered a multi-year partnership with Newcastle United.
  • August 2025: BYDFi launched BYDFi Card.
  • February 2026: BYDFi launched TradFi trading on Web and App, extending access to stocks, gold, and silver.
  • March 2026: BYDFi integrated perpetual futures market data into TradingView.

Global Presence, Industry Recognition, and the Reliability Behind the Platform

From June 2025 through March 2026, BYDFi built visibility across Asia and Europe through appearances in Seoul, Bali, Lisbon, Hong Kong, Bucharest, and Warsaw, strengthening industry connections and reinforcing BYDFi's long-term market commitment.

Over the same period, BYDFi received the following industry recognitions:

  1. Trusted Exchange Award at the TrustFinance Performance Awards
  2. Outstanding Crypto Trading Platform at the FinanceFeeds Awards
  3. BeInCrypto recognition in the Best Centralized Exchange (CEX) category
  4. Best All-in-One Crypto Trading Platform at Crypto Expo Europe 2026
  5. Best Global Crypto Trading Platform at Next Block Expo 2026

Behind this progress is the operating foundation BYDFi continues to build around reliability. BYDFi holds MSB registrations in the U.S. and Canada and is a member of South Korea's CODE VASP Alliance. BYDFi also maintains 100%+ Proof of Reserves with periodic public reporting and reinforces this transparency with an 800 BTC Protection Fund. Together with 24/7 multilingual support and timely official-channel responses, these measures reflect a user-first standard built for clarity, protection, and trust.

Looking Ahead: Building the Next Chapter of BYDFi

BYDFi is entering the next stage with a continued focus on product strength, user protection, and long-term trust. Michael, Co-Founder and CEO of BYDFi, shares:

"Six years is an important milestone for BYDFi, but what matters more is what BYDFi continues to build from here. Users expect consistency, clear standards, and continuous improvement as needs evolve."

He further adds, "For BYDFi, the next chapter is about strengthening the fundamentals: better infrastructure, stronger user protections, broader market access, and a trading experience designed to be practical, stable, and trusted over the long term."

About BYDFi

Established in 2020, BYDFi is a global crypto trading platform that combines the power of a centralized exchange (CEX) with an integrated onchain trading module. Recognized by Forbes as one of the Best Crypto Exchanges In Canada For 2026, BYDFi offers intuitive, low-fee trading across Spot and Perpetual Contracts to Copy Trading, and Automated Crypto Trading Bots, empowering both new and experienced traders to navigate digital assets with confidence.

BYDFi is dedicated to delivering a world-class crypto trading experience for every user.

BUIDL Your Dream Finance.

Twitter( X ) | LinkedIn | Telegram | YouTube | TikTok | How to Buy on BYDFi

VICTORIA, Seychelles, April 1, 2026 /PRNewswire/ -- Global crypto trading platform BYDFi will mark its 6th anniversary with a month-long celebration beginning on April 1, 2026, highlighting BYDFi's evolution into an all-in-one crypto trading platform built on a CEX + DEX dual-engine model. Over six years, BYDFi has strengthened infrastructure, user safeguards, and market access, reinforcing an operating foundation built for reliability.

A Month-Long Celebration for BYDFi's 6th Anniversary

Beginning on April 1, 2026, BYDFi's anniversary program will feature rewards of more than $1,000,000 USDT.

BYDFi's anniversary campaign will center on three major events: Warm-Up Tasks, covering onboarding, first trades, fiat purchase rewards, referrals, and community participation; Shoot to Win, a football-themed lucky-draw experience; and the Futures Golden Ball Cup, a two-round futures trading competition.

Together, these three events give both new and existing users more ways to join BYDFi's 6th anniversary while reflecting BYDFi's broader journey over the past six years.

For more event details, please visit the official website: BYDFi 6th Anniversary.

BYDFi's Evolution: From Core Trading to Broader Market Access

Over the past six years, BYDFi has grown into a global crypto trading platform serving more than 1 million users across 190+ countries and regions. Since launch, BYDFi has broadened product offerings, strengthened user safeguards, and expanded across both centralized and onchain trading.

Recent milestones shaped BYDFi's growth:

  • July 2025: BYDFi supported tokenized U.S. equities through xStocks.
  • August 2025: BYDFi entered a multi-year partnership with Newcastle United.
  • August 2025: BYDFi launched BYDFi Card.
  • February 2026: BYDFi launched TradFi trading on Web and App, extending access to stocks, gold, and silver.
  • March 2026: BYDFi integrated perpetual futures market data into TradingView.

Global Presence, Industry Recognition, and the Reliability Behind the Platform

From June 2025 through March 2026, BYDFi built visibility across Asia and Europe through appearances in Seoul, Bali, Lisbon, Hong Kong, Bucharest, and Warsaw, strengthening industry connections and reinforcing BYDFi's long-term market commitment.

Over the same period, BYDFi received the following industry recognitions:

Behind this progress is the operating foundation BYDFi continues to build around reliability. BYDFi holds MSB registrations in the U.S. and Canada and is a member of South Korea's CODE VASP Alliance. BYDFi also maintains 100%+ Proof of Reserves with periodic public reporting and reinforces this transparency with an 800 BTC Protection Fund. Together with 24/7 multilingual support and timely official-channel responses, these measures reflect a user-first standard built for clarity, protection, and trust.

Looking Ahead: Building the Next Chapter of BYDFi

BYDFi is entering the next stage with a continued focus on product strength, user protection, and long-term trust. Michael, Co-Founder and CEO of BYDFi, shares:

"Six years is an important milestone for BYDFi, but what matters more is what BYDFi continues to build from here. Users expect consistency, clear standards, and continuous improvement as needs evolve."

He further adds, "For BYDFi, the next chapter is about strengthening the fundamentals: better infrastructure, stronger user protections, broader market access, and a trading experience designed to be practical, stable, and trusted over the long term."

About BYDFi

Established in 2020, BYDFi is a global crypto trading platform that combines the power of a centralized exchange (CEX) with an integrated onchain trading module. Recognized by Forbes as one of the Best Crypto Exchanges In Canada For 2026, BYDFi offers intuitive, low-fee trading across Spot and Perpetual Contracts to Copy Trading, and Automated Crypto Trading Bots, empowering both new and experienced traders to navigate digital assets with confidence.

BYDFi is dedicated to delivering a world-class crypto trading experience for every user.

BUIDL Your Dream Finance.

Twitter( X ) | LinkedIn | Telegram | YouTube | TikTok | How to Buy on BYDFi

** This press release is distributed by PR Newswire through automated distribution system, for which the client assumes full responsibility. **

BYDFi Marks 6th Anniversary with Month-Long Celebration, Built for Reliability

BYDFi Marks 6th Anniversary with Month-Long Celebration, Built for Reliability

BYDFi Marks 6th Anniversary with Month-Long Celebration, Built for Reliability

BYDFi Marks 6th Anniversary with Month-Long Celebration, Built for Reliability

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