Skip to Content Facebook Feature Image

Accelerating Drug Discovery: Tsingke Biotech Unveils Next-Generation Rapid Protein and Antibody Solutions

Business

Accelerating Drug Discovery: Tsingke Biotech Unveils Next-Generation Rapid Protein and Antibody Solutions
Business

Business

Accelerating Drug Discovery: Tsingke Biotech Unveils Next-Generation Rapid Protein and Antibody Solutions

2025-11-19 22:17 Last Updated At:22:35

BEIJING and LISBON, Portugal, Nov. 19, 2025 /PRNewswire/ -- At PEGS Europe 2025, one of the industry's premier gatherings for innovation in protein and antibody engineering, Tsingke Biotech highlighted its latest accelerated protein and antibody services. The leading Chinese biotechnology company announced that its services can generate proteins in as little as 3 days and produce antibodies within 7 days, offering a potential step-change in speed for biopharma developers aiming to shorten drug discovery timelines worldwide.

High-Speed Protein Production Across Six Expression Systems

Tsingke Biotech combines advanced gene synthesis, automated expression, and purification technologies to deliver rapid protein production. The company supports six expression systems—including E. coli, Bacillus subtilis, yeast, insect, mammalian, and cell-free systems—allowing simple proteins to be produced in 3 days via cell-free methods, while complex proteins and antibodies are ready in 7–14 days. According to Tsingke, overall protein expression success reaches 95%.

Accelerated Antibody Discovery and Production

Traditional hybridoma-based antibody development can take 1–2 months. Tsingke's Single-B Cell Antibody Discovery Service preserves natural VH/VL pairing and generates high-affinity antibodies (10⁻⁸–10⁻¹² M), utilizing FACS technology. The service is engineered for efficiency, delivering full, comprehensive results in a remarkable timeframe of just 8–10 weeks. Furthermore, the supported formats encompass a broad spectrum of therapeutic antibodies sourced from both mouse and rabbit models, ensuring versatility for critical research and development needs.

In addition, for antibody production, Tsingke uses Expi293 and CHO-K1 systems, achieving milligram-scale yields in 7 days and gram-scale yields in 14 days, with average production exceeding 300 mg/L. A broad range of antibody formats, including VHH-His and VHH-Fc, are available.

Tsingke Biotech Draws Strong Industry Interest at PEGS Summit

Tsingke Biotech's booth at the PEGS Summit attracted attention from global biopharma professionals, with many visitors engaging in discussions and companies exploring potential collaborations. This reflects the growing demand for innovative solutions in protein and antibody production.

Comment from Tsingke Biotech

"PEGS is a key event for protein and antibody engineering," said Nan Zhang, Global Marketing Manager at Tsingke Biotech. "Our service's combination of speed, customization, and quality is designed to help the biopharma industry meet the growing demand for faster drug development."

Tsingke's subsidiary operates ISO 13485-certified facilities with state-of-the-art Class 100,000 cleanroom environments, ensuring high standards of quality and a smooth transition from research-grade to GLP/GMP-compliant workflows.

About Tsingke

Beijing Tsingke Biotech Co., Ltd. is a leading biotechnology company that provides comprehensive solutions for research and therapeutic development. With expertise in molecular biology, genetics, and protein science, Tsingke offers custom DNA/RNA synthesis, gene cloning, protein expression, antibody discovery, and viral vector packaging (AAV, LV, AdV). Its production environments, certified with ISO 13485 and Class 100,000 cleanrooms, ensure consistent quality and reliability. Backed by advanced automation and a global scientific team, Tsingke accelerates innovation in drug discovery, functional genomics, and genetic engineering, thereby empowering researchers worldwide with cutting-edge biomanufacturing solutions.

For news and updates, follow Tsingke Biotech on LinkedIn.

Media Contact

info@tsingke.com.cn

** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **

Accelerating Drug Discovery: Tsingke Biotech Unveils Next-Generation Rapid Protein and Antibody Solutions

Accelerating Drug Discovery: Tsingke Biotech Unveils Next-Generation Rapid Protein and Antibody Solutions

SHANGHAI, April 1, 2026 /PRNewswire/ -- Smartee Denti-Technology today announced the addition of Material Choice and Trimline Selection features to its digital case management system SmarteeCheck. Available immediately at the case approval stage, these updates provide clinicians with greater flexibility to further customize treatment plans based on personal preferences and dental condition of individual patients.

Material Choice: Balancing Precision and Comfort

Clinicians can now select between Softer and Standard dental sheets when approving a case. This dual-option approach addresses the advanced clinical understanding that different phases of tooth movement require different mechanical properties.

Smartee's Softer material is suited for treatment stages where patient comfort and initial compliance are priorities, while the Standard material provides the sustained force expression needed for robust control. This functionality allows clinicians to select the appropriate material for each treatment phase without having to switch aligner systems.

Trimline Selection: Evidence from Industry Studies

The update also allows clinicians to choose from three distinct trimline styles at case approval: Classic Scalloped, Scalloped Extended, and Straight.

This feature aligns with recent clinical studies on aligner biomechanics and aesthetics. A systematic review published in BMC Oral Health noted that trimline design influences orthodontic tooth movement efficacy by affecting force delivery and aligner retention. Additionally, an eye-tracking study in the American Journal of Orthodontics and Dentofacial Orthopedics (AJODO) confirmed that different trimline designs impact how aligners are visually perceived.

To meet diverse clinical requirements, the system offers:

  • Classic Scalloped Trimline: Precisely conforms to the gingival margin for improved aesthetics and comfort.
  • Scalloped Extended Trimline: Extends beyond the margin to enlarge the surface area in the maxillary posterior buccal region for enhanced retention.
  • Straight Trimline: A straight horizontal trimming at the gingival zenith, delivering maximum retention force.

Clinical Flexibility
While some clear aligner systems offer a single standard trimline, Smartee's update enables doctors to easily toggle between three distinct styles at case approval. This supports personalized treatment planning by allowing orthodontists to balance retention, force control, and gingival aesthetics according to each patient's specific clinical profile.

Availability
The Material Choice and Trimline Selection features are available globally starting March 31, 2026, for all new case approvals through Smartee's digital case management system.

** This press release is distributed by PR Newswire through automated distribution system, for which the client assumes full responsibility. **

Smartee Introduces Material and Trimline Selection Features to Enhance Aligner Customization

Smartee Introduces Material and Trimline Selection Features to Enhance Aligner Customization

Smartee Introduces Material and Trimline Selection Features to Enhance Aligner Customization

Smartee Introduces Material and Trimline Selection Features to Enhance Aligner Customization

Recommended Articles