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Oklo and DOE Partner to Deploy Radioisotope Pilot Facility Supporting Cancer Care and U.S. Medical Supply Chains

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Oklo and DOE Partner to Deploy Radioisotope Pilot Facility Supporting Cancer Care and U.S. Medical Supply Chains
Business

Business

Oklo and DOE Partner to Deploy Radioisotope Pilot Facility Supporting Cancer Care and U.S. Medical Supply Chains

2026-01-07 21:04 Last Updated At:01-09 15:32

SANTA CLARA, Calif.--(BUSINESS WIRE)--Jan 7, 2026--

Oklo Inc. (NYSE: OKLO) (“Oklo”), an advanced nuclear technology company, announced today that it has signed a U.S. Department of Energy (DOE) Other Transaction Agreement (OTA) to support the design, construction, and operation of a radioisotope pilot plant (“Radioisotope Pilot Facility”) under the DOE Reactor Pilot Program (RPP). Signing the OTA is a major milestone which marks the transition from project selection and planning into active execution under DOE authorization.

This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20260107011601/en/

“This OTA establishes a framework for execution and risk reduction. By building and operating a pilot reactor, we generate the data and experience to streamline future commercial deployments, improve regulatory efficiency, and deliver long-term value,” said Jacob DeWitte, co-founder and CEO of Oklo.

Atomic Alchemy Inc., an Oklo subsidiary, is using the Radioisotope Pilot Facility to lay the groundwork for future commercial plants that make medical and research radioisotopes in the United States. These radioisotopes are essential for diagnosing cancer, treating disease, powering medical research, and supporting national security. Today, many are produced overseas or in aging facilities. By first operating a pilot plant, Oklo can then scale into reliable, domestic production that helps ensure hospitals, researchers, and patients have consistent access to these lifesaving materials.

With the OTA now in place, Atomic Alchemy will focus its near-term resources on building the Radioisotope Pilot Facility under DOE authorization. As part of this learn-first-then-scale strategy, Atomic Alchemy has withdrawn its previously submitted Nuclear Regulatory Commission construction permit application for the Meitner-1 commercial radioisotope production facility at Idaho National Laboratory to focus on the Radioisotope Pilot Facility.

Oklo views the RPP as an enabler and accelerator to deliver advanced nuclear technologies that strengthen U.S. energy security, healthcare infrastructure, and industrial leadership.

About Oklo Inc.: Oklo Inc. is developing fast fission power plants to deliver clean, reliable, affordable energy at scale, establishing a domestic supply chain for critical radioisotopes, and advancing nuclear fuel recycling to convert nuclear waste into clean energy. Oklo was the first to receive a site use permit from the U.S. Department of Energy for a commercial advanced fission plant, was awarded fuel from Idaho National Laboratory, and submitted the first custom combined license application for an advanced reactor to the U.S. Nuclear Regulatory Commission. Oklo is also developing advanced fuel recycling technologies in collaboration with the U.S. Department of Energy and U.S. National Laboratories.

Forward-Looking Statements

This press release includes statements that express Oklo’s opinions, expectations, objectives, beliefs, plans, intentions, strategies, assumptions, forecasts or projections regarding future events or future results and therefore are, or may be deemed to be, “forward-looking statements.” The words “may,” “will,” “could,” “should,” “expects,” “anticipates,” “intends,” “plans,” “believes,” “seeks,” “estimates,” “continue,” “might,” “possible,” “potential,” “predict,” “project,” “goal,” “would,” “commit,” or, in each case, their negative or other variations or comparable terminology, and similar expressions may identify forward-looking statements, but the absence of these words does not mean that a statement is not forward-looking. These forward-looking statements include all matters that are not historical facts. They appear in a number of places throughout this press release and include statements regarding our intentions, beliefs or current expectations concerning, among other things, results of operations, financial condition, liquidity, prospects, growth, strategies and the markets in which Oklo operates. Such forward-looking statements are based on information available as of the date of this press release, and current expectations, forecasts and assumptions, and involve a number of judgments, risks and uncertainties.

As a result of a number of known and unknown risks and uncertainties, the actual results or performance of Oklo may be materially different from those expressed or implied by these forward-looking statements. The following important risk factors could affect Oklo’s future results and cause those results or other outcomes to differ materially from those expressed or implied in the forward-looking statements: risks related to the development and deployment of Oklo’s powerhouses; the risk that Oklo is pursuing an emerging market with no commercial project operating and regulatory uncertainties; risks related to acquisitions, divestitures, or joint ventures we may engage in; the need for financing to construct plants, which remain subject to market, financial, political, and legal conditions; risks related to an inability to raise additional capital to support our business and sustain our growth on favorable terms; the effects of competition; risks related to accessing high-assay low-enriched uranium, plutonium, and other fuels at acceptable costs (including recycled fuels); risks related to our supply chain; risks related to power purchase agreements; risks related to human capital; risks related to our intellectual property; risks related to cybersecurity and data privacy; changes in applicable laws or regulations, including tariffs; the outcome of any government and regulatory proceedings and investigations and inquiries; and the other factors set forth in our documents we have filed with the U.S. Securities and Exchange Commission (the “SEC”).

The foregoing list of factors is not exhaustive. You should carefully consider the foregoing factors and the other risks and uncertainties of the other documents filed by Oklo from time to time with the SEC. The forward-looking statements contained in this press release are based on current expectations and beliefs concerning future developments and their potential effects on Oklo. There can be no assurance that future developments affecting Oklo will be those that Oklo has anticipated. Oklo undertakes no obligation to update or revise any forward-looking statements to reflect events or circumstances after the date of this presentation, except as may be required by law.

Render of Atomic Alchemy radioisotope pilot facility (Image: Hillside Architecture, PLLC)

Render of Atomic Alchemy radioisotope pilot facility (Image: Hillside Architecture, PLLC)

There are primary elections Tuesday in Kentucky, Alabama, Georgia, Oregon, Idaho and Pennsylvania. These contests will be a further test of President Donald Trump 's grip on Republican voters.

In Kentucky, Ed Gallrein won Republican nomination for U.S. House in Kentucky’s 4th Congressional District, beating incumbent Thomas Massie. Trump handpicked Gallrein after Massie broke with him over issues including the release of the Jeffrey Epstein files. .

In Georgia, Republicans are choosing a challenger to take on Democratic Sen. Jon Ossoff. Trump has not endorsed a candidate, which could lead to a runoff on June 16. There’s also a bruising Republican primary for governor. Most polls are closed.

In Alabama, Republican voters will choose a U.S. Senate candidate to replace Tommy Tuberville, who is running for governor. Polls have closed.

In Pennsylvania, Democratic voters will pick their nominees to flip four Republican-held seats seen as critical for the party to retake the U.S. House. The races will be a test of Gov. Josh Shapiro’s influence. Polls have closed.

In Oregon, Democratic Gov. Tina Kotek will face nearly two dozen challengers. Voters will also decide whether to raise gas taxes to pay for improvements to the state’s roads and bridges. Voting concludes at 11 p.m. ET.

In Idaho, voters are picking their party's nominees for governor and U.S. Senate. Voting concludes at 11 p.m. ET.

The Latest:

“He was a bad guy. He deserves to lose,” Trump told reporters following Massie’s defeat, another sign of Trump’s enduring grip on the Republican base.

Trump allies quickly celebrated the victory online. Chris LaCivita, Trump’s 2024 co-campaign manager, posted a photo of Trump raising his middle finger and tagged Massie in the post.

“Do not ever doubt President Trump and his political power,” Trump spokesperson Steven Cheung wrote on social media.

The Pennsylvania governor urged the crowd at his primary election rally to help the party’s candidates win control of the state Legislature for the first time in more than three decades.

Josh Shapiro, who is putting his clout on the line in congressional and legislative races, said he will advance a stronger agenda with Democratic control in Harrisburg.

“Give me a Democratic majority in the Senate and we will fully fund mass transit, we will build more housing, and we will codify abortion rights into state law,” Shapiro said.

The former college football coach entered politics with his election to the U.S. Senate in 2020. Tuberville opted not to seek a second term and instead launched a bid for governor.

During his time in the Senate, Tuberville was closely aligned with Trump, who endorsed Tuberville in 2020 and has also backed his bid for governor. “Tommy Tuberville has my Complete and Total Endorsement to be the next Governor of the Great State of Alabama – COACH TUBERVILLE WILL NEVER LET YOU DOWN!” Trump wrote on social media.

During the primary, opponent Ken McFeeters accused Tuberville of not meeting the legal requirement to have lived in the state for seven years. Tuberville maintains he meets the residency requirement, and the Alabama Republican Party dismissed McFeeters’ challenge.

Jones emphasized his previous political victories in his speech after advancing to the Georgia governor runoff. He said he cut taxes and regulations and was tough on public safety and election integrity.

He acknowledged the president, who endorsed him, during his roughly 10 minutes of remarks.

“I could not leave this stage without thanking President Donald J. Trump,” he said.

Jackson took shots at Burt Jones after advancing to a June 16 runoff, saying Jones “was all talk and no results.”

And while Jones was endorsed by Trump, Jackson said he would be Trump’s “favorite governor.”

“As governor, I’ll be like Trump but with a southern tongue,” said Jackson.

In announcing that he conceded defeat to Gallrein, Massie also made a jab at his opponent over the millions of dollars poured in to the race by pro-Israel groups to try to defeat the incumbent.

“I would have come out sooner, but I had to call my opponent and concede and it took a while to find Ed Gallrein in Tel Aviv,” Massie told the crowd.

Massie has voted against U.S. aid to Israel and faced accusations of antisemitism. He has denied the charges, arguing that he is generally against all foreign aid.

The race drew in millions of dollars against Massie from pro-Israel interest groups, including from the Republican Jewish Coalition Victory Fund

Stelson, a one-time local TV anchor and personality, lost in 2024 to Perry by barely a percentage point in the right-leaning 10th District.

Stelson was backed by Shapiro and the House Democrats’ campaign arm, the Democratic Congressional Campaign Committee.

Stelson beat progressive challenger Justin Douglas for the right to challenge Perry again in the Harrisburg-area district.

After unseating Massie with strong backing from Trump, Gallrein pledged to take the party’s agenda to Washington and work closely with the president. His victory speech lasted around five minutes.

“We have a saying on the family farm that it’s a contact sport,” Gallrein said. “I can tell you that campaigning is one as well folks.”

Trump-endorsed Georgia Lt. Gov. Burt Jones was the frontrunner for much of the lead-up to tonight’s gubernatorial primary, until health care executive and billionaire Rick Jackson entered the race just a few months ago.

Jackson spent millions of his own dollars to flood the state with campaign ads.

Many candidates backed by the president have enjoyed comfortable victories in their elections this primary season, but few have been up against a candidate with such a large campaign budget. Jones and Jackson have advanced to a June 16 runoff election.

The Kentucky congressman claimed in his speech after his defeat that young voters were still on his side.

“People that want somebody that will go along to get along, I’ve never heard of that strategy but that seems to be what the voters want,” Massie said. “But not the young voters.”

The crowd was still energetic despite Massie’s loss, and started a chant of “No more wars!” that the congressman joined in on. Massie’s speech meandered through different topics and touched on other politicians before another chant started of “America First!”

“We stirred up something. There is a yearning in this country for someone who will vote for principles over party,” Massie said.

Gov. Josh Shapiro was uncontested in Tuesday’s primary. He’s seeking a second term in the fall and puts his clout on the line in the battleground state ahead of a potential 2028 bid for the White House.

The 52-year-old has made his opposition to Trump’s agenda a central focus of his reelection campaign.

Shapiro is on track to break his own fundraising record. He’s working to flip important Republican-held U.S. House seats and deliver the first Democratic-controlled state Legislature in more than three decades.

Republican state Treasurer Stacy Garrity ran uncontested for the GOP’s nomination.

Shapiro — who made Kamala Harris’ short list for a vice presidential running mate in 2024 — has never said whether he’s actually interested in running for president.

The president, who had waged his own social media campaign against Massie, posted a photo showing him and Gallrein under the words “Ed Gallrein Wins! Endorsed by President Trump!”

The two-term state treasurer was uncontested in the GOP primary.

Garrity is running as a strong backer of Trump’s agenda as she attempts to be the first Republican to win the office in Pennsylvania since 2010.

Shapiro ran uncontested for the Democratic Party’s nomination to seek a second term.

Garrity lagged badly behind Shapiro in fundraising after winning two relatively low-profile races for treasurer.

The result showed the president’s persisting influence over GOP voters, adding to a growing number of Trump-backed primary challengers to defeat Republican lawmakers who angered him in his second term.

Massie, who has served in Congress since 2012, fell into Trump’s crosshairs in part by pushing for the release of the Jeffrey Epstein files and denouncing the war in Iran.

Gallrein, a former Navy Seal who avoided making public appearances on the campaign trail, ran on his military service and loyalty to the president. He accused Massie of forsaking Trump and the party.

Gallrein is expected to win the general election in the deeply red district.

The Pennsylvania governor’s election night rally is being held in a converted centrifuge where the U.S. Navy once tested g-forces on astronauts.

The crowd of local Democrats began trickling in to the Fuge after 7 p.m. ET, ordering drinks and picking at appetizers in a circular event space with a vaulted ceiling and a wraparound projection screen where astronauts used to be tested to the limits of human tolerance to gravity and acceleration.

The location — in suburban Philadelphia’s Bucks County — is symbolic because it in a congressional district where Gov. Josh Shapiro is trying to help Democrats knock off Republican U.S. Rep. Brian Fitzpatrick and take back control of Congress.

Shapiro ran unopposed for the nomination in his reelection bid and was expected to speak after 9 p.m. ET. He was expected to appear later with his endorsed candidate in the district, Democrat Bob Harvie.

The Georgia secretary of state’s office said that won’t delay reporting for the rest of the county’s results.

A judge ordered a precinct at Ison Springs Elementary School to stay open until 11:02 p.m. because the school was placed on lockdown just before noon and remained closed until 4 p.m. over an incident that was unrelated to the election, the Secretary of State’s office said.

Sandy Springs police said officers responded to a call about a man dressed in military-style gear and reports of possible gunshots fired in the area. After an extensive manhunt, a suspect was taken into custody, police said.

Eleven Cobb County precincts were also staying open late, with delayed closures ranging from six minutes to an hour.

U.S. Rep. Andy Barr, who was endorsed by Trump, beat Daniel Cameron, a former state attorney general who leaned into his Christianity on the campaign trail.

The winner in November will replace U.S. Sen. Mitch McConnell, who is stepping down in a generational changing of the guard for Republicans.

Trump swayed the race not just through his endorsement but by offering a third challenger, Nate Morris, an ambassadorship just over two weeks before Election Day. Morris, who fashioned himself as the MAGA candidate, withdrew from the race and encouraged his backers to support Barr.

Barr was first elected in 2012 in the 6th Congressional District. He is expected to win the general election in the Republican-dominated state.

Eleven polling places in Georgia’s Cobb County, in the Atlanta suburbs, will be staying open late because of issues that arose during the day.

Blake Evans, who oversees elections for the secretary of state’s office, said the precincts were staying open because of problems with the electronic poll pads that are used to to check in voters. The extensions range from six minutes at one location to an hour at another, according to a judge’s order.

Deputy Secretary of State Matt Tyser said they are waiting on an order from a Fulton County judge to extend voting at a precinct in Sandy Springs, just north of Atlanta. That’s because a “law enforcement issue” that was unrelated to the election forced the closure of the polling place for several hours.

Most polls in Georgia are set to close at 7 p.m. ET.

Most of the polls in the state closed at 6 p.m. ET, including in the 4th District where U.S. Rep. Thomas Massie is up against Ed Gallrein in the Republican primary that’s garnered national attention.

The president picked Gallrein to compete against Massie, who’s frustrated Trump partly by pushing for the release of the Jeffrey Epstein files.

Western Kentucky is in the Central Time Zone and polls there close at 7 p.m. ET.

Five of Oregon’s six congressional districts are held by Democrats.

Its 5th District, considered the most competitive, was flipped by Republicans for the first time in decades in 2022 but reclaimed by Democrats in 2024. The district stretches from southern Portland across the Cascade Range to Bend.

The incumbent, Democratic Rep. Janelle Bynum, is running against a primary opponent who has not reported raising any money.

Two candidates, a county commissioner and a political consultant, are running in the district’s GOP primary in the hope of trying to win the seat back for Republicans in November.

Both Democratic Gov. Josh Shapiro and Republican Stacy Garrity are running unopposed in their primaries.

Shapiro is heavily favored to win reelection this fall over Garrity, the state treasurer.

Republicans acknowledge Shapiro’s electoral strength, and may hope that Garrity can at least make it a close contest to help protect the party’s other candidates on the ballot in contests for Congress and the state Legislature.

Tuberville could face former U.S. Sen. Doug Jones, a Democrat, if both men secure their parties’ nominations.

The two last competed in the 2020 Senate race, when Tuberville easily defeated Jones, who was then the incumbent. Tuberville was boosted by a Trump endorsement and his high profile from his years as a football coach.

Jones, a former U.S. attorney, won a 2017 special election for U.S. Senate over Republican Roy Moore. Jones remains the last Democrat to win a statewide race in Alabama.

When Geoff Duncan was Georgia’s lieutenant governor, he resisted Trump’s efforts to overturn Joe Biden’s victory in the state in 2020. He’s since left the Republican Party, and he’s running for governor as a Democrat.

His campaign has involved a lot of apologizing to win over voters who may be turned off by his previously conservative positions.

It’s an interesting example of how traditional partisan lines have been scrambled since Trump rose to power a decade ago. Many Republicans who have crossed the president have retired or been defeated in primaries. Only a few of them have attempted to switch parties like Duncan.

Incumbent Tina Kotek is expected to win the Democratic primary and advance to November’s general election.

Elected to her first term as governor in 2022 after years in the Legislature, Kotek pledged to tackle homelessness, mental health and education. Despite approving funding and programs aimed at those issues, the state has continued to see rising homelessness and flagging student test scores that have failed to return to pre-pandemic levels.

Kotek also has sparred with the Trump administration, which sought to deploy the National Guard to Portland last fall during its immigration crackdown for the stated purpose of protecting federal property and personnel.

After the state and city sued to block the deployment, a federal judge found that protests at Portland’s U.S. Immigration and Customs Enforcement building didn’t meet the conditions for using the military domestically under federal law.

The president supported an opponent to Massie, just as he has done elsewhere.

On May 5, several Indiana state senators who defied Trump on redistricting lost their primaries to candidates backed by the president.

On May 16, Sen. Bill Cassidy lost his primary in Louisiana. Rep. Julia Letlow, who Trump endorsed, and state Treasurer John Fleming will compete in a runoff.

Cassidy had voted to convict Trump during an impeachment trial over the Jan. 6 attack on the U.S. Capitol.

Massie angered Trump by voting against his signature tax legislation over concerns of adding to the national debt, pushing for the release of the Jeffrey Epstein files and opposing his decision to go to war with Iran.

His positions, Massie insists, reflect the America First promises Trump initially made on the campaign trail.

In a Kentucky district where the president won by 35 points two years ago, Massie told The Associated Press that this primary is “by far the most challenging reelection I’ve ever faced.”

Voters have sent Massie back to Congress ever since his first election in 2012, embracing his stalwart independence and jaunty personality. Back in 2020, they brushed off Trump’s social media demand to throw Massie out of the Republican Party because he was a “third rate Grandstander.”

Their names may seem familiar.

The Democratic field in Kentucky includes former state lawmaker Charles Booker and former Marine pilot Amy McGrath. McGrath beat Booker and several other candidates in the 2020 Democratic primary to face McConnell.

Democrats have not won a U.S. Senate race in Kentucky since 1992.

Pennsylvania’s governor is also a potential 2028 presidential candidate. With his own primary uncontested, he’s been spending money and support on Democrats running for U.S. House and the state Legislature.

Shapiro is on track to break his own campaign spending record and, in a step to help races up and down the ballot, has plunged more than $900,000 so far this election cycle into the state Democratic Party’s accounts.

The election year is an opportunity for Shapiro to show his political strength in a premier battleground state should he decide to run for president in 2028.

U.S. Sen. Chris Coons, D-Delaware, said Trump is continuing a “campaign of retribution” against his political enemies.

He suggested that the latest example is Secretary of Defense Pete Hegseth campaigning — “during a war” — against U.S. Rep. Tom Massie ahead of Kentucky’s primary on Tuesday.

“That continues to prevent Republicans from having the courage to speak out on matters of principle, which I think is putting all of us at risk,” Coons told reporters in the U.S. Capitol on Tuesday.

Massie angered Trump by opposing his signature tax legislation over concerns about the national debt, pushing for the release of the Jeffrey Epstein files and opposing his decision to go to war with Iran.

They are being asked whether to approve a 6-cent-a-gallon gas tax increase passed by the Democratic-controlled Legislature last fall.

They’ve been casting ballots as prices at the pump have skyrocketed because of the war with Iran.

Democrats increased the tax and other fees to help pay for road improvements and plug a hole in the state’s transportation budget. Republicans responded by launching a successful referendum campaign to refer the tax and fee increases to the ballot, saying they drive the cost of living even higher.

Democrats say the main cause of skyrocketing gas prices is Trump’s decision to go to war with Iran. But they’ve acknowledged the difficult timing of the ballot measure, which has also complicated national Democrats’ affordability messaging in midterm campaigning.

Kentucky will release the first results of the night.

In the 2024 primaries, the AP reported the first Kentucky votes six minutes after most polls closed at 6 p.m. ET. The last vote update of the night was at 9:47 p.m.

Georgia will be next, with polls closing at 7 p.m. ET. In the 2022 state primaries, results were available at 13 minutes after polls closed. The last vote update of the night was at 3:29 a.m.

Polls in Alabama and Pennsylvania close at 8 p.m. ET, and both states started releasing votes at roughly the same time in the 2024 primaries — at 8:01 p.m. and 8:03 p.m., respectively. Both stopped counting for the night around 2 a.m.

Idaho and Oregon are expected to begin releasing votes just as voting concludes at 11 p.m. ET. In their last state primaries, Oregon began releasing votes right at 11 p.m. and Idaho at 11:09 p.m. Idaho’s last update of the night was at 4:51 a.m., while Oregon’s last update was at 5:11 a.m.

A sign directs voters arriving to vote in the Georgia primary elections on Tuesday, May 19, 2026, in Atlanta. (AP Photo/Brynn Anderson)

A sign directs voters arriving to vote in the Georgia primary elections on Tuesday, May 19, 2026, in Atlanta. (AP Photo/Brynn Anderson)

Pennsylvania Gov. Josh Shapiro walk to speaks with members of the media outside his polling place in Rydal, Pa., Tuesday, May 19, 2026. (AP Photo/Matt Rourke)

Pennsylvania Gov. Josh Shapiro walk to speaks with members of the media outside his polling place in Rydal, Pa., Tuesday, May 19, 2026. (AP Photo/Matt Rourke)

A person walks outside a polling place in Philadelphia, Tuesday, May 19, 2026. (AP Photo/Matt Rourke)

A person walks outside a polling place in Philadelphia, Tuesday, May 19, 2026. (AP Photo/Matt Rourke)

Richard Cullom leaves a voting center after voting, Tuesday, May 19, 2026, in Marietta, Ga. (AP Photo/Mike Stewart)

Richard Cullom leaves a voting center after voting, Tuesday, May 19, 2026, in Marietta, Ga. (AP Photo/Mike Stewart)

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