Results demonstrate a favorable safety profile and functional improvements in patients with severe tricuspid regurgitation including patients with reduced right ventricle function
YOKNEAM, Israel, Jan. 21, 2026 /PRNewswire/ -- Trisol Medical, a clinical-stage medical device company developing a transcatheter tricuspid valve replacement system, today announced positive results from its FDA-approved U.S. Early Feasibility Study evaluating the Trisol Transcatheter Tricuspid Valve in patients with severe to torrential tricuspid regurgitation.
Trisol's Transcatheter Tricuspid Valve Replacement (TTVR) system is designed to treat severe to torrential tricuspid regurgitation (TR), a condition in which the tricuspid valve fails to close properly, allowing blood to flow backward from the right ventricle to the right atrium. Patients with this condition often have limited treatment options.
To date, 22 patients with severe to torrential TR who were considered high risk for conventional surgery have been treated at leading U.S. centers, including Piedmont Heart Institute, Vanderbilt University Medical Center, University of Virginia Health System, Columbia University Medical Center, and Cedars-Sinai Medical Center, using a trans-jugular (TJ) access approach. Enrollment in the TJ cohort is now complete, and the study is proceeding with continued enrollment using Trisol's newly developed trans-femoral access route.
Key Study Results
- Safety: Less than 5% need for permanent pacemaker at 30-day follow-up.
- Effectiveness: Considerable reduction in TR following implantation.
- Functional outcomes: At 30-day and 12-month follow-up, notable improvements were observed in quality of life (KCCQ), heart failure symptoms (NYHA class), 6-minute walk distance, right ventricular function, and cardiac output.
- Technical performance: Successful deployment of the device and no incidents of migration.
Importantly, these encouraging results include patients with reduced right ventricular function, a large, high-risk subgroup associated with poorer outcomes and underserved by existing and emerging treatment approaches. Early clinical experience reported to date across emerging therapies highlights a persistent unmet need in this patient population, suggesting the Trisol valve could help address this critical gap.
Dr. Pradeep Yadav commented: "Trisol brings several novel features from ease of use to recapturable anchors, broad size range, lower pacemaker rate and performance in dysfunctional right ventricles. We are very excited to investigate the next phase with its transfemoral delivery system and pivotal trial."
"We are thrilled by these positive outcomes, which further validate the potential of our best-in-class technology to improve care for patients with severe TR. I would like to thank our clinical investigators and the entire clinical teams for their dedication and outstanding patient care," said Ron Davidson, CEO of Trisol Medical.
Dr. Shimon Eckhouse, Chairman of Trisol, added: "Millions of Americans suffer from TR, and despite recent advances, effective treatment options remain limited for patients with severe TR. The Trisol valve was developed to address this significant unmet need and has the potential to redefine the standard of care."
About Trisol Medical
Trisol Medical Ltd. is a clinical-stage medical device company specializing in the development of a novel TTVR. Founded within the Alon MedTech Ventures incubator, Trisol is dedicated to advancing minimally invasive heart valve therapies that offer safer alternatives to traditional surgical procedures. For further details, please visit: www.trisol-medical.com.
Media contact:
Ron Davidson
CEO
rond@trisol-medical.com
** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **
Trisol Medical Announces Positive Results from U.S. Early Feasibility Study of Its Transcatheter Tricuspid Valve Replacement System
- DXC integrates Ripple's institutional-grade blockchain technology into its Hogan core banking platform, which supports $5 trillion in deposits and 300 million accounts globally
- The collaboration enables financial institutions to bridge legacy finance with enterprise blockchain-based solutions without disrupting core banking infrastructure
ASHBURN, Va., Jan. 21, 2026 /PRNewswire/ -- DXC Technology (NYSE: DXC), a leading enterprise technology and innovation partner, today announced a strategic partnership with Ripple, a financial technology company that offers crypto solutions for businesses, to help banks seamlessly adopt digital asset custody and payment capabilities at enterprise scale.
As regulated financial institutions navigate an era of exponential change, digital asset adoption depends on accessible, secure blockchain infrastructure. Through this collaboration, DXC and Ripple enable financial institutions and fintechs to access digital asset technology seamlessly, bridging legacy financial systems with onchain finance. The solution enables programmable payments and the tokenization, custody, and transfer of digital assets—allowing institutions to deliver regulated digital asset use cases without disrupting mission-critical core banking systems.
Leveraging DXC's Hogan core banking platform, which powers more than 300 million deposit accounts and over $5 trillion in deposits globally, the initiative integrates Ripple's digital asset custody and payments technology into large-scale banking environments, providing Hogan clients with a streamlined path to deliver digital custody and payment capabilities.
"For digital assets to move into the financial mainstream, institutions need secure custody and seamless payment capabilities," said Sandeep Bhanote, Global Head and General Manager of Financial Services at DXC. "Our work with Ripple brings those capabilities together in a way that allows banks to engage in the digital asset ecosystem without changing their core systems, connecting traditional accounts, wallets and decentralized platforms at enterprise scale."
By delivering last-mile connectivity between regulated banking infrastructure and digital asset platforms, the collaboration helps financial institutions move beyond experimentation and into real-world deployment of blockchain-enabled use cases. Fintechs also benefit from simplified access to the banking relationships required to support compliant custody and payment solutions.
"Banks are under increasing pressure to modernize while continuing to operate on complex infrastructure," said Joanie Xie, VP and Managing Director, North America at Ripple. "Our partnership with DXC brings digital asset custody, RLUSD and payments directly into the core banking environments institutions already trust. Together, we're enabling banks to deliver secure, compliant digital asset use cases at enterprise scale without disruption."
The DXC–Ripple partnership reinforces DXC's commitment to helping financial institutions modernize safely and innovate responsibly. This represents a significant step forward in enabling digital asset adoption across production banking environments worldwide through an integrated core banking approach.
Ripple Payments is a licensed, end-to-end cross-border payment solution that enables Ripple to manage the flow of funds on behalf of its customers. Ripple Custody is designed for banks and financial institutions to securely manage digital assets, stablecoins or Real World Assets (RWAs).
About DXC Technology
DXC Technology (NYSE: DXC) is a leading enterprise technology and innovation partner delivering software, services, and solutions to global enterprises and public sector organizations — helping them harness AI to drive outcomes at a time of exponential change with speed. With deep expertise in Managed Infrastructure Services, Application Modernization, and Industry-Specific Software Solutions, DXC modernizes, secures, and operates some of the world's most complex technology estates. Learn more on dxc.com
About Ripple
Ripple is a financial technology company that offers crypto solutions for businesses. Ripple Payments uses blockchain to make cross-border payments faster, more transparent, and widely accessible. Ripple Custody offers customers a secure way to store and manage digital assets. Through Ripple Prime, the company offers a global, multi-asset prime brokerage for institutional customers. Ripple's stablecoin (RLUSD) and the cryptocurrency, XRP, are leveraged across these solutions to make traditional finance more efficient and enable new ways to utilize digital assets.
Media Contacts: DXC, Ashley Houk-Temple, ashley.houktemple@dxc.com; Ripple: Amy Dunn, Press@ripple.com
ASHBURN, Va., Jan. 21, 2026 /PRNewswire/ -- DXC Technology (NYSE: DXC), a leading enterprise technology and innovation partner, today announced a strategic partnership with Ripple, a financial technology company that offers crypto solutions for businesses, to help banks seamlessly adopt digital asset custody and payment capabilities at enterprise scale.
As regulated financial institutions navigate an era of exponential change, digital asset adoption depends on accessible, secure blockchain infrastructure. Through this collaboration, DXC and Ripple enable financial institutions and fintechs to access digital asset technology seamlessly, bridging legacy financial systems with onchain finance. The solution enables programmable payments and the tokenization, custody, and transfer of digital assets—allowing institutions to deliver regulated digital asset use cases without disrupting mission-critical core banking systems.
Leveraging DXC's Hogan core banking platform, which powers more than 300 million deposit accounts and over $5 trillion in deposits globally, the initiative integrates Ripple's digital asset custody and payments technology into large-scale banking environments, providing Hogan clients with a streamlined path to deliver digital custody and payment capabilities.
"For digital assets to move into the financial mainstream, institutions need secure custody and seamless payment capabilities," said Sandeep Bhanote, Global Head and General Manager of Financial Services at DXC. "Our work with Ripple brings those capabilities together in a way that allows banks to engage in the digital asset ecosystem without changing their core systems, connecting traditional accounts, wallets and decentralized platforms at enterprise scale."
By delivering last-mile connectivity between regulated banking infrastructure and digital asset platforms, the collaboration helps financial institutions move beyond experimentation and into real-world deployment of blockchain-enabled use cases. Fintechs also benefit from simplified access to the banking relationships required to support compliant custody and payment solutions.
"Banks are under increasing pressure to modernize while continuing to operate on complex infrastructure," said Joanie Xie, VP and Managing Director, North America at Ripple. "Our partnership with DXC brings digital asset custody, RLUSD and payments directly into the core banking environments institutions already trust. Together, we're enabling banks to deliver secure, compliant digital asset use cases at enterprise scale without disruption."
The DXC–Ripple partnership reinforces DXC's commitment to helping financial institutions modernize safely and innovate responsibly. This represents a significant step forward in enabling digital asset adoption across production banking environments worldwide through an integrated core banking approach.
Ripple Payments is a licensed, end-to-end cross-border payment solution that enables Ripple to manage the flow of funds on behalf of its customers. Ripple Custody is designed for banks and financial institutions to securely manage digital assets, stablecoins or Real World Assets (RWAs).
About DXC Technology
DXC Technology (NYSE: DXC) is a leading enterprise technology and innovation partner delivering software, services, and solutions to global enterprises and public sector organizations — helping them harness AI to drive outcomes at a time of exponential change with speed. With deep expertise in Managed Infrastructure Services, Application Modernization, and Industry-Specific Software Solutions, DXC modernizes, secures, and operates some of the world's most complex technology estates. Learn more on dxc.com
About Ripple
Ripple is a financial technology company that offers crypto solutions for businesses. Ripple Payments uses blockchain to make cross-border payments faster, more transparent, and widely accessible. Ripple Custody offers customers a secure way to store and manage digital assets. Through Ripple Prime, the company offers a global, multi-asset prime brokerage for institutional customers. Ripple's stablecoin (RLUSD) and the cryptocurrency, XRP, are leveraged across these solutions to make traditional finance more efficient and enable new ways to utilize digital assets.
Media Contacts: DXC, Ashley Houk-Temple, ashley.houktemple@dxc.com; Ripple: Amy Dunn, Press@ripple.com
** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **
DXC Partners with Ripple to Empower Global Banks with Scalable Digital Asset Custody and Payments
