HONG KONG SAR - Media OutReach Newswire - 3 February 2026 - Liver cancer is one of the three deadliest cancers worldwide, and metabolic dysfunction-related cases have become increasingly common in recent years. A research team from The Hong Kong Polytechnic University (PolyU) has identified a protein secreted by fat cells that promotes cancer growth and has successfully developed a novel antibody that neutralises this protein, marking a significant breakthrough in impeding the progression of liver cancer. The research findings have been published in the Journal of Clinical Investigation.
Metabolic dysfunction-associated steatotic liver disease (MASLD), commonly known as fatty liver disease, currently affects around a quarter of the global population and is an important risk factor for liver cancer. In affected individuals, fat cells induce insulin resistance and chronic inflammation, leading to excessive fat accumulation in the liver. This ultimately impairs liver function and may progress to liver cancer. Treatment options for MASLD-induced liver cancer remain limited and the effectiveness of current immunotherapies is suboptimal.
A breakthrough study led by Prof. Terence LEE, Associate Head and Professor of the PolyU Department of Applied Biology and Chemical Technology, and his research team has revealed that an adipocyte-derived protein, known as fatty acid-binding protein 4 (FABP4) is a key driver that accelerates tumour growth. Through mass spectrometry, the team confirmed that patients with MASLD-induced liver cancer had markedly elevated FABP4 levels in their serum. Further investigations showed that FABP4 activates a series of pro-proliferative signalling pathways within cells, causing cancer cells to multiply and grow more rapidly.
Prof. Lee's team has successfully developed a monoclonal antibody that neutralises FABP4. This antibody not only inhibits the growth and proliferation of FABP4-driven cancer stem cells, but also enhances the ability of immune cells to combat cancer.
Prof. Lee said, "This neutralising antibody against FABP4 demonstrates significant potential in inhibiting tumour growth and activating immune cells, providing a complementary approach to current immunotherapy strategies. Our findings highlight that targeting adipocyte-derived FABP4 holds promise for treating MASLD-induced liver cancer."
Prof. Lee added that gaining deeper insights into how adipocyte-derived FABP4 affects liver cancer cells helps to explicate the disease mechanisms of liver cancer, particularly in obese individuals. Intervening in the relevant signalling pathways could provide effective methods to combat this aggressive malignancy.
Prof. Lee believes that, as this adipocyte-targeted immunotherapy continues to mature, it will bring more treatment options to MASLD patients. He remarked, "If its efficacy can be proven in clinical trials, it could offer new hope to many affected individuals."
The research is supported by the Innovation and Technology Fund of the Innovation and Technology Commission of the Government of the Hong Kong Special Administrative Region of the People's Republic of China. PolyU has filed a non-provisional patent for the developed antibody and is continuing to optimise its binding affinity to facilitate future clinical applications.
Hashtag: #PolyU #FattyLiver #Cancer #LiverCancer #理大 #香港理工大学 #肝癌 #癌症 #脂肪肝
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Prof. Terence Lee, Associate Head and Professor of the PolyU Department of Applied Biology and Chemical Technology, and his research team have developed a novel antibody targeting the adipocyte-derived protein FABP4, offering a new approach to treating metabolism-related liver cancer.
CHANG ZHOU, CHINA - Media OutReach Newswire - 7 July 2026 - The global new energy vehicle market has seen rapid growth in recent years. With continued strong expectations for new energy vehicle exports, the global electric vehicle (EV) charging market is entering a new stage of rapid expansion. Recently, StarCharge, the global leading brand of EV Charging equipment and smart energy systems, held a major industry seminar in Hong Kong and released two new white papers at the event, exploring two major transformative trends in the industry that are worth paying attention to.
StarCharge Releases Industry White Papers: From Infrastructure to Network Systems, Microgrids Moving from Customization to Scaling Up Development
Charging stations are becoming a key connection of smart energy systems
According to the 'Technical White Paper' by StarCharge, for years, EV charging infrastructure has mainly been seen as support for vehicle sales expansion: building more chargers, expanding coverage, and speeding up charging.
However, this role is starting to change.
As electrification scales up, charging networks are becoming a part of the energy system itself. They are no longer just places for vehicles to top up; they are evolving into smart energy nodes connecting vehicles, the grid, distributed energy, storage, and digital management.
This shift from charging infrastructure to charging network systems shows that the industry is moving from basic access to integrated value: from charging services to energy services, from standalone stations to PV-storage-charging systems, from equipment deployment to scenario-based infrastructure.
StarCharge believes that the future charging network ecosystem will go through four major turning points.
Four Key Points Reshaping the Ecosystem
1. Charging Networks Are Becoming Energy Infrastructure
Charging infrastructure is going beyond its original role as just a support for EVs. As EV adoption grows, charging networks are becoming strategic energy infrastructure: they connect mobility demand with the grid, distributed energy, storage, digital platforms, and future energy services.
2. Defining the Scenarios for the Network
The future charging network won't be shaped by hardware alone. Policies determine whether infrastructure should be built, technology determines the speed of construction, but real-world scenarios determine what the charging network actually needs to look like.
Urban commuting, highway trips, ride-hailing, logistics fleets, county and rural coverage, holiday peak demand, heavy trucks, mining areas, ports, airports, and autonomous driving all create different charging needs. Therefore, a mature charging network can't be 'one-size-fits-all'; it has to be designed around different vehicle types, operating hours, power requirements, reliability needs, and grid conditions.
3. Digital platforms turn charging networks into operable assets
A large charging network only truly has value when it can be scaled, optimized, and managed. This is exactly the core role of cloud platforms. They turn millions of charging points, users, stations, transactions, and energy flows into a measurable, controllable, and continuously optimized operating system.
StarCharge's platform capabilities cover site selection, pricing, marketing, station operations, smart maintenance, charging safety, station robots, AI-based smart charging, fleet management, energy optimization, and ESG reporting. In other words, digital platforms are the key to transforming charging infrastructure from a heavy-asset network into smart, operable, and scalable assets.
4. Charging stations are becoming grid-friendly energy resources
The next-generation charging infrastructure won't be defined by any single technology. It will be built on a complete tech stack, combining high-power charging, liquid cooling, integrated PV-storage-charging, DC bus architecture, V2G, automated charging, and AI-driven operations. In other words, future charging stations shouldn't just be passive electricity consumers that add stress to the grid. Through energy storage, renewable energy integration, V2G, smart scheduling, and AI-based energy optimization, charging stations can become grid-friendly energy resources.
This means that aside from charging vehicles, a charging station can absorb renewable energy, buffer peak loads, respond to demand-side signals, support peak shaving and valley filling, regulate frequency, and provide carbon-neutral ESG data for fleet operators. Its business model will also go beyond charging fees, creating new value through energy services, data services, carbon-related benefits, and grid interaction capabilities.
Microgrids Have Emerged at the Right Time
At the same time, with the continuous development of distributed energy and photovoltaic energy, microgrids have emerged at the right time. They are not just a product, but a local energy system built around real-world scenarios.
In the latest "White Paper" on scenario-based microgrid technology, StarCharge points out that microgrids are moving from customized engineering projects toward scalable, replicable energy systems.
StarCharge Releases Industry White Papers: From Infrastructure to Network Systems, Microgrids Moving from Customization to Scaling Up Development
A microgrid is a scenario-based local energy system
According to StarCharge, a microgrid is not a single device, nor is it just an energy storage product. It's a local energy system designed around the needs of a specific scenario, coordinating local generation, loads, storage, control, and operational strategies within a defined electrical boundary.
Moreover, depending on the scenario—such as data centers, individual charging stations, zero-carbon industrial parks, or green mines—the energy challenges are completely different. The right microgrid is defined by the scenario it serves.
The white paper also highlights four high-value paths: electricity-computing synergy, independent power supply, zero-carbon parks, and green mines. In areas with weak grids or limited grid access, microgrids ensure the operation of critical loads. In emerging load scenarios like data centers and industrial parks, microgrids support renewable energy integration, energy resilience, and cost optimization. In high-tech-demand scenarios like mines, microgrids become the foundation for ensuring production continuity, energy transition, and ESG competitiveness.
The three-stage evolution of microgrids
As power sources and loads become increasingly DC, microgrid architectures are evolving from AC-dominated systems to AC-DC hybrid systems, and eventually toward microgrids with a higher proportion of DC.
Microgrid 1.0 — dominated by AC architecture. It integrates renewable energy into the existing AC grid framework, but its control heavily relies on grid-following management and support from the external grid.
Microgrid 2.0 — the AC-DC hybrid stage. AC and DC buses coexist, allowing PV, storage, and DC loads to connect more directly. Bidirectional power hubs, solid-state transformers (SST), and energy routers become important bridges between AC and DC systems. This stage balances strong AC compatibility with higher DC efficiency and is expected to remain mainstream in the next 10-15 years.
Microgrid 3.0—it's the era of DC microgrids. As solar PV, wind power, battery storage, data centers, LED lighting, and EV charging increasingly move toward DC, DC microgrids can reduce repeated AC-DC conversion losses, simplify control, and support millisecond-level responses.
This evolution is closely linked to the mission of microgrids: breaking through energy access bottlenecks, enabling sustainable development, connecting technology, industry, policy, market, and community needs, and unlocking the integrated value of local energy systems.
In the future, StarCharge will steadily expand into the growing global markets for new EVs and renewable energy, building on its smart energy systems that have been widely validated in the Chinese market.
Hashtag: #StarCharge
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