Catherine O'Hara died from a pulmonary embolism. Cancer was the underlying cause

LOS ANGELES (AP) — Catherine O’Hara died from a pulmonary embolism, with cancer as the underlying cause.

A Los Angeles County death certificate issued Monday lists the pulmonary embolism, which occurs when a blood clot blocks an artery in the lungs, as the immediate cause of the actor's Jan. 30 death at age 71. Rectal cancer was the long-term cause.

The oncologist who signed off on the certificate indicated that he had been treating O'Hara since March of last year, and last saw her on Jan. 27. She died at a hospital in Santa Monica, California.

The beloved Canadian-born comic actor and “SCTV” alum starred as Macaulay Culkin's mother in two “Home Alone” movies and won an Emmy as the dramatically oblivious wealthy matriarch Moira Rose in “Schitt’s Creek.”

Her death was a surprise to most, and an initial statement from her representatives said only that she died “following a brief illness.”

Collaborators including Culkin, Christopher Guest, Eugene Levy and Pedro Pascal paid her loving tribute after her death.

The document said she was cremated. It lists her profession as “actress” and her business as movies. It said she practiced her trade for 50 years.

FILE - Catherine O'Hara arrives at the 77th Primetime Emmy Awards in Los Angeles on Sept. 14, 2025. (Photo by Richard Shotwell/Invision/AP, File)

FILE - Eugene Levy, from left, Annie Murphy, Daniel Levy and Catherine O'Hara cast members in the series "Schitt's Creek" pose for a portrait during the 2018 Television Critics Association Winter Press Tour in Pasadena, Calif., on Jan. 14, 2018. (Photo by Willy Sanjuan/Invision/AP, File)

FILE - Catherine O'Hara, a cast member in the Apple+ series "The Studio," poses for a portrait on Thursday, March 20, 2025, in Los Angeles. (AP Photo/Chris Pizzello, File)

FILE - Catherine O'Hara poses for photographers upon arrival at the UK premiere of "Beetlejuice Beetlejuice" on Thursday, Aug. 29, 2024, in London. (Photo by Scott A Garfitt/Invision/AP)

TUCSON, Ariz. (AP) — Savannah Guthrie 's family is “at an hour of desperation” in the search for her missing mother, the “Today” show host said in a video released Monday, just hours before a purported ransom deadline apparently set by Nancy Guthrie ’s abductors.

Savannah Guthrie didn’t mention the deadline in the video, saying her family in Arizona continues to believe their 84-year-old mother is out there and hearing everyone’s prayers.

“She was taken and we don’t know where, and we need your help,” Guthrie said in the video posted on Instagram, which urged people nationwide to be on the lookout. “No matter where you are, even if you’re far from Tucson, if you see anything, if you hear anything.”

The mysterious disappearance and search has riveted the country. — from President Donald Trump, who spoke with Savannah Guthrie last week, to the online sleuths who’ve flooded social media with tips, theories and rumors.

Multiple news outlets have received alleged ransom letters during the past week. At least one letter made monetary demands and set deadlines for receiving the money. The first deadline passed last Thursday but a second one was set for Monday evening.

Law enforcement officials declined to affirm that the letters were credible but said all tips were being investigated seriously.

Authorities say they have growing concerns about Nancy Guthrie’s health because she needs daily medication. She is said to have a pacemaker and has dealt with high blood pressure and heart issues, according to sheriff’s dispatcher audio on broadcastify.com.

Savannah Guthrie expressed hope on Monday that her mom is still alive.

“We believe that somehow, some way, she is feeling these prayers,” Guthrie said, “and that God is lifting her even in this moment and in this darkest place.”

Savannah Guthrie said in a video Saturday that the family was prepared to pay for her mother’s return. “This is the only way we will have peace. This is very valuable to us, and we will pay.”

Authorities believe Nancy Guthrie was taken against her will from her home just outside Tucson. She was last seen there on Jan. 31 and reported missing the next day after not attending church services. DNA tests showed blood on Guthrie’s front porch was a match to her, and her doorbell camera was disconnected in the early hours of Sunday morning, Pima County Sheriff Chris Nanos has said.

Outside the home on Monday, neighbors strolled by on their morning jogs and walks, while a county sheriff's deputy remained stationed out front.

Detectives and agents carried out follow-up work in her neighborhood and other locations over the weekend as part of the investigation, the Pima County Sheriff’s Department said Sunday. “Investigators have not identified any suspects, persons of interest, or vehicles connected to this case,” the department said.

Investigators on Saturday were inside daughter Annie Guthrie’s home, about 4 miles (6 kilometers) from Nancy Guthrie's house. On Sunday, an investigator was seen using a pole to search an underground tank behind Nancy Guthrie’s home.

A person walks a dog as members of the Pima County sheriffs office remains outside of Nancy Guthrie's home, Monday, Feb. 9, 2026 in Tucson, Ariz. (AP Photo/Ty ONeil)

A member of the Pima County sheriffs office remains outside of Nancy Guthrie's home, Monday, Feb. 9, 2026 in Tucson, Ariz. (AP Photo/Ty ONeil)

FILE - This image provided by the Pima County Sheriff's Department on Feb. 2, 2026, shows a missing person alert for Nancy Guthrie. (Pima County Sheriff's Department via AP, File)

A member of the Pima County sheriffs office stands by his truck looking at Nancy Guthrie‘s house, Monday, Feb. 9, 2026 in Tucson, Ariz. (AP Photo/Ty ONeil)

Nancy Guthrie’s home in Tucson, Ariz., on Saturday, Feb. 7, 2026 (AP Photo/Ty ONeil)

Lit candles next to a sign from neighbors supporting the Guthrie family outside of Nancy Guthrie’s house in the early morning hours of Sunday, Feb. 8, 2026 in Tucson, Ariz. (AP Photo/Ty ONeil)