BEVERLY, Mass.--(BUSINESS WIRE)--Feb 23, 2026--
seqWell, a global leader in NGS library construction technology, today announced the launch of MosaiX, a next-generation library prep kit designed to streamline a wide range of high-throughput applications, including human WGS, large plant and animal genomics, and hybrid capture workflows such as Whole Exome Sequencing (WES) and other targeted panels. The announcement coincides with the Advances in Genome Biology and Technology (AGBT) General Meeting to be held in Orlando, Florida, from Feb 23-27, 2026, where seqWell will be showcasing data from the new product.
This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20260223523287/en/
As genomic research scales to larger populations with increasing data requirements, laboratories often face a trade-off between workflow, speed and data quality. MosaiX eliminates this compromise by utilizing seqWell’s proprietary engineered TnX™ transposase in a novel directional tagmentation workflow. The MosaiX product enables researchers to quickly and affordably generate uniform libraries with low insertion bias using a 90-minute end-to-end workflow, requiring only 35 minutes of hands-on time.
MosaiX Library Prep has already been deployed in early access by leading genomic research institutions. Chad Nusbaum, Board Member and lead for genomics technology development for Darwin's Ark, a pet science nonprofit, has utilized the kit for a large-scale feline genomics initiative using fur samples as input. "The scale of our feline genomics project requires a library construction solution that is robust, scalable and simple to carry out, and, importantly, also capable of generating sufficient data from low input samples of mammalian-complexity genomes," said Nusbaum. "MosaiX has been a game-changer for our process. It allows us to process large numbers of diverse samples rapidly without sacrificing the coverage uniformity or library complexity essential for our downstream analysis. It works really well, and the data look great."
"With MosaiX, we set out to solve a fundamental challenge in library prep: how to achieve the convenience of tagmentation with the high-performance levels typically required for complex human and large plant or animal genomes," said Joseph Mellor, Chief Scientific Officer and Co-Founder of seqWell. "By integrating our engineered TnX transposase into a directional tagmentation workflow, we are providing scientists with a tool that offers uncompromised versatility and data quality, with the speed and scalability they have come to expect from seqWell products."
seqWell will be presenting MosaiX performance data and additional product details at the upcoming Advances in Genome Biology and Technology (AGBT) General Meeting. The MosaiX DNA Library Prep Kit will be available for purchase in March. For more information, please visit www.seqwell.com.
About seqWell
seqWell creates scalable genomics technologies that simplify library preparation workflows and help scientists to unlock transformative discoveries with sequencing. seqWell technology is focused on a novel, next-generation transposase, TnX™, to drive the scalability and high-performance needs of tagmentation and advance NGS. seqWell offers a range of library prep products and fragmentation workflows that allow customers to quickly and easily scale their short- and long-read sequencing initiatives. Learn more at www.seqwell.com or follow us on Linkedin.
MosaiX High-Performance DNA Library Prep from seqWell using TnX next-generation transposase and directional tagmentation for rapid, affordable, and scalable NGS library preparation.
GUADALAJARA, Mexico (AP) — Several Mexican states canceled school on Monday, with local and foreign governments warning their citizens to stay inside after widespread violence erupted following the army's killing of the powerful leader of the Jalisco New Generation Cartel.
Nemesio Rubén Oseguera Cervantes, known as “El Mencho” was the boss of one of the fastest-growing criminal networks in Mexico, notorious for trafficking fentanyl, methamphetamine and cocaine to the United States and staging brazen attacks against government officials who challenged it.
He was killed during a shoot-out in his home state of Jalisco as the Mexican military attempted to capture him. Cartel members responded with violence across the country, blocking roads and setting fire to vehicles.
President Claudia Sheinbaum urged calm and authorities announced late Sunday they had cleared most of the more than 250 cartel roadblocks across 20 states. The president was expected to address the situation at her daily news briefing Monday morning.
The White House confirmed that the U.S. provided intelligence support to the operation to capture the cartel leader and applauded Mexico's army for taking down a man who was one of the most wanted criminals in both countries.
Mexico hoped the death of the world's biggest fentanyl traffickers would ease Trump administration pressure to do more against the cartels, but many remained hunkered down and on edge as they waited to see the powerful cartel's reaction.
The U.S. Embassy said via X that its personnel in eight cities and the state of Michoacan would shelter in place and work remotely Monday and it warned U.S. citizens in many parts of Mexico to do the same.
Cars began circulating in Guadalajara before sunrise Monday with the start of the work week, a notable change from Sunday when Jalisco's state capital and Mexico's second-largest city was almost completely shut down as fearful residents stayed home.
More than 1,000 people were stuck in Guadalajara’s zoo overnight, sleeping in buses. On Monday morning. mothers wrapped up in blankets carried their toddlers out of the buses for a much-needed bathroom break as police trucks guarded the area.
Luis Soto Rendón, the zoo’s director, said many had been trapped there since 9 a.m. the day before, when violence broke out in Jalisco and the surrounding states. Families were left stranded, trying to distract their children, as they decided they couldn't return home in nearby states like Zacatecas and Michoacan.
“We decided to let people stay inside the zoo for their safety,” Soto said. “There are small children and senior citizens.”
Irma Hernández, a 43-year-old hotel security guard in Guadalajara, arrived at work early Monday morning.
She normally takes public transportation to work, but buses were not running and she had no way to cross the city. Her bosses organized a private car to pick her up. Her family, she said, was staying at home, too scared to leave.
“I am worried because I don't know how to get home if something happens,” she said.
Passengers arriving at the city's international airport Sunday night were told it was operating with limited personnel because of the burst of violence.
Authorities in Jalisco, Michoacan and Guanajuato reported at least 14 other people killed Sunday, including seven National Guard troops.
Videos circulating on social media Sunday showed tourists in Puerto Vallarta walking on the beach with smoke rising in the distance.
David Mora, Mexico analyst for International Crisis Group, said the capture and outburst of violence marks a point of inflection in Sheinbaum’s push to crack down on cartels and relieve U.S. pressures.
U.S. President Donald Trump has demanded Mexico do more to fight the smuggling of the often-deadly drug fentanyl, threatening to impose more tariffs or take unilateral military action if the country does not show results.
There were early signs that Mexico’s efforts were well received by the United States.
U.S. Ambassador Ron Johnson recognized the success of the Mexican armed forces and their sacrifice in a statement late Sunday. He added that “under the leadership of President Trump and President Sheinbaum, bilateral cooperation has reached unprecedented levels.”
But it may also pave the way for more violence as rival criminal groups take advantage of the blow dealt to the CJNG, Mora said.
“This might be a moment in which those other groups see that the cartel is weakened and want to seize the opportunity for them to expand control and to gain control over Cartel Jalisco in those states,” he said.
“Ever since President Sheinbaum has been in power, the army has been way more confrontational, combative against criminal groups in Mexico,” Mora said. “This is signaling to the U.S. that if we keep cooperating, sharing intelligence, Mexico can do it. We don’t need U.S. troops on Mexican soil."
Oseguera Cervantes, who was wounded in the operation to capture him Sunday in Tapalpa, Jalisco, about a two-hour drive southwest of Guadalajara, died while being flown to Mexico City, the Defense Department said in a statement.
During the operation, troops came under fire and killed four people at the location. Three more people, including Oseguera Cervantes, were wounded and later died, the statement said.
White House press secretary Karoline Leavitt said via X that the U.S. government provided intelligence support for the operation. “‘El Mencho’ was a top target for the Mexican and United States government as one of the top traffickers of fentanyl into our homeland,” she wrote. She commended Mexico’s military for its work.
The U.S. State Department had offered a reward of up to $15 million for information leading to the arrest of El Mencho. The Jalisco New Generation Cartel is one of the most powerful and fastest-growing criminal organizations in Mexico and began operating around 2009.
In February 2025, the Trump administration designated the cartel as a foreign terrorist organization.
Sheinbaum has criticized the “kingpin” strategy of previous administrations that took out cartel leaders, only to trigger explosions of violence as cartels fractured. While she has remained popular in Mexico, security is a persistent concern and since U.S. President Donald Trump took office a year ago, she has been under tremendous pressure to show results against drug trafficking.
The Jalisco cartel has been one of the most aggressive cartels in its attacks on the military — including on helicopters — and is a pioneer in launching explosives from drones and installing mines. In 2020, it carried out a spectacular assassination attempt with grenades and high-powered rifles in the heart of Mexico City against the then head of the capital’s police force and now federal security secretary.
Sánchez reported from Mexico City. Associated Press writer María Verza in Mexico City contributed to this report.
A National Guard patrols the area outside of the General Prosecutor's headquarters in Mexico City, Sunday, Feb. 22, 2026, after authorities reported that the Mexican Army killed Jalisco New Generation Cartel leader Nemesio Oseguera, known as "El Mencho." (AP Photo/Ginette Riquelme)
Charred vehicles sit in a parking lot sit outside a shopping mall in Guadalajara, Jalisco state, Mexico, Sunday, Feb. 22, 2026, as authorities reported that the Mexican Army killed Jalisco New Generation Cartel leader Nemesio Oseguera, known as "El Mencho." (AP Photo/Alejandra Leyva)
National Guards patrol the area outside of the General Prosecutor's headquarters in Mexico City, Sunday, Feb. 22, 2026, after authorities reported that the Mexican Army killed Jalisco New Generation Cartel leader Nemesio Oseguera, known as "El Mencho." (AP Photo/Ginette Riquelme)
Carts stand outside of a vandalized supermarket in Guadalajara, Jalisco state, Mexico, Sunday, Feb. 22, 2026, after the death of the leader of the Jalisco New Generation Cartel, Nemesio Rubén Oseguera Cervantes, known as "El Mencho." (AP Photo/Alejandra Leyva)
Army soldiers patrol outside the National Palace ahead of the daily, morning news conference by Mexican President Claudia Sheinbaum in Mexico City, Monday, Feb. 23, 2026. (AP Photo/Ginnette Riquelme)
A police officer stands guard by a charred vehicle after it was set on fire, on a road in Guadalajara, Jalisco state, Mexico, Sunday, Feb. 22, 2026, after the death of the leader of the Jalisco New Generation Cartel, Nemesio Rubén Oseguera Cervantes, known as "El Mencho." (AP Photo/Alejandra Leyva)
A charred vehicle sits at a damaged supermarket in Guadalajara, Jalisco state, Mexico, Sunday, Feb. 22, 2026, after the death of the leader of the Jalisco New Generation Cartel, Nemesio Rubén Oseguera Cervantes, known as "El Mencho." (AP Photo/Alejandra Leyva)
National Guards remove pedestrians by the General Prosecutor's headquarters in Mexico City, Sunday, Feb. 22, 2026, after the death of the leader of the Jalisco New Generation Cartel, Nemesio Rubén Oseguera Cervantes, known as "El Mencho." (AP Photo/Ginette Riquelme)
A soldier stands guard by a charred vehicle after it was set on fire, in Cointzio, Michoacán state, Mexico, Sunday, Feb. 22, 2026, following the death of the leader of the Jalisco New Generation Cartel, Nemesio Oseguera, known as "El Mencho." (AP Photo/Armando Solis)
A man rides a bike next to a convenience store that was set on fire, in San Francisco del Ricon, Guanajuato state, Mexico, Sunday, Feb. 22, 2026, after the death of the leader of the Jalisco New Generation Cartel, Nemesio Ruben Oseguera Cervantes, known as "El Mencho." (AP Photo/Alfredo Valadez)
