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Illumina introduces the MiSeq i100 Series: its simplest, fastest benchtop sequencers

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Illumina introduces the MiSeq i100 Series: its simplest, fastest benchtop sequencers
Business

Business

Illumina introduces the MiSeq i100 Series: its simplest, fastest benchtop sequencers

2024-10-24 10:00 Last Updated At:10:15

Designed to make next-generation sequencing accessible to more labs

With room-temperature kit storage and shipping, Illumina's newest sequencers remove barriers to enable more insights and discoveries

SAN DIEGO, Oct. 24, 2024 /PRNewswire/ -- Illumina, Inc. (NASDAQ: ILMN), a global leader in DNA sequencing and array-based technologies, today unveiled its MiSeqâ„¢ i100 Series of sequencing systems, delivering unparalleled benchtop speed and simplicity to advance next-generation sequencing (NGS) for labs.

The two new benchtop instruments, MiSeq i100 and MiSeq i100 Plus Systems, will empower customers to unlock powerful insights through an affordable, comprehensive solution that is simple to understand and use, even for those with limited NGS expertise. Room-temperature storage and shipping enable labs to sequence on demand, with no delays for thaw time, and same-day sample-to-analysis.

"Our customers told us they need a faster, smaller, and easy-to-use instrument, and that's what we're delivering with the MiSeq i100," said Jacob Thaysen, PhD, CEO of Illumina. "Whether you are an established next-generation sequencing lab, or looking to start sequencing for the first time, our latest benchtop instrument adds the plug-and-play flexibility that today's labs are seeking."

The MiSeq i100 Series builds on the legacy of the original benchtop MiSeq System, which Illumina customers have used since 2011 to power a host of genomic discoveries. Completely redesigned and incorporating the groundbreaking technology and chemistry of the NovaSeqâ„¢ X Series, the MiSeq i100 will help to fuel the next era of genomics growth and discovery.  

Key technology enhancements

The MiSeq i100 Series brings Illumina's powerful XLEAP-SBS™ chemistry innovation even further—for the first time, harnessing the potential of room-temperature storage and shipping, which provides customers greater flexibility in how they plan and execute their projects while reducing their environmental impact. It offers flexible output capabilities and comes in two configurations: the MiSeq i100 Plus System has the full 100 million single-end reads per run, and the MiSeq i100 System has a maximum of 25 million single-end reads per run. Key features include:

  • Room-temperature shipping and storage for reagents: Eliminating the cold chain and allowing for greater flexibility to sequence on demand without the need to thaw reagents, which is critical for running urgent samples
  • Sustainability: An 85% reduction in packaging waste compared to the MiSeq System supports a lower carbon footprint
  • Speed: Dramatic reduction in run times: as fast as four hours, with same-day results (4× faster than MiSeq)
  • Cost efficiency: Cost-effective consumables enable more affordable sequencing
  • Turnkey workflows: 18 proven end-to-end workflows across 10 applications
  • Simplicity: Simpler, streamlined operations for various levels of sequencing experience

Push-button workflows on MiSeq i100 are available for small whole-genome sequencing for microbiology and targeted NGS panels for both infectious disease and oncology. Workflows provide metrics either directly on the instrument or via cloud-based DRAGENâ„¢ genomic data analysis, minimizing the need for bioinformatics expertise.

"The MiSeq i100 symbolizes Illumina's commitment to delivering total systems with complete workflows that allow our customers to accomplish more," said Steve Barnard, PhD, chief technology officer of Illumina. "With its enhanced speed, simplicity, scalability, and quality–and its intuitive user experience–the MiSeq i100 sets a new standard for benchtop sequencing."

Customer reactions

Illumina conducted early access testing of MiSeq i100 with customers around the world. Geneviève DonPierre, team leader of NGS Sequencing at Génome Québec, shared her lab's experience with the instrument, noting that most of the sequencing operations at the Center of Expertise and Services of Génome Québec are conducted on the NovaSeq X Plus. "With this new instrument, we are able to provide answers quickly for small projects or for researchers who need fast answers to determine whether or not they should pursue their project." 

Génome Québec is a nonprofit organization that provides genomic services for researchers in the academic and industrial fields of 45 countries. DonPierre noted the importance of room temperature storage for her lab: "It really helps the planning for the sequencing run. We don't have to think two days before to get a kit out of the freezer. So it really is a game changer to have kits stored at room temperature."

Tim Roloff Handschin, PhD, co-leader of Microbial Genomics (NGS) at the Institute for Medical Microbiology at the University of Zurich, and his team conduct research on developing new diagnostic tests, antimicrobial resistance and antimicrobial drugs. In his lab's experience with MiSeq i100, the ease of use and being able to achieve a turnaround time from bacterial culture to results within 24 hours will be transformative.

"We can start two runs on the same day and thereby increase our sample flow massively. And given that the reagents are shipped at room temperature, we don't need to wait for the cartridges to thaw," Roloff said. "We can just launch a run whenever we're ready with a new pool and there is no planning needed upfront. This gives us great flexibility, and this can provide new possibilities to develop new tests."

The new instrument was unveiled during a virtual customer event; a replay may be viewed here. The MiSeq i100 will be available to ship globally in 2025. For more information, visit the website.

Use of forward-looking statements

This release may contain forward-looking statements that involve risks and uncertainties. Among the important factors to which our business is subject that could cause actual results to differ materially from those in any forward-looking statements are: (i) challenges inherent in developing, manufacturing, and launching new products and services; (ii) our ability to manufacture robust instrumentation and consumables; (iii) customer uptake of, and satisfaction with new products and services; and (iv) the speed and scale of new product adoption by customers, together with other factors detailed in our filings with the Securities and Exchange Commission, including our most recent filings on Forms 10-K and 10-Q, or in information disclosed in public conference calls, the date and time of which are released beforehand. We undertake no obligation, and do not intend, to update these forward-looking statements, to review or confirm analysts' expectations, or to provide interim reports or updates on the progress of the current quarter.

About Illumina

Illumina is improving human health by unlocking the power of the genome. Our focus on innovation has established us as a global leader in DNA sequencing and array-based technologies, serving customers in the research, clinical, and applied markets. Our products are used for applications in the life sciences, oncology, reproductive health, agriculture, and other emerging segments. To learn more, visit illumina.com and connect with us on X, Facebook, LinkedIn, Instagram, TikTok, and YouTube.

Designed to make next-generation sequencing accessible to more labs

With room-temperature kit storage and shipping, Illumina's newest sequencers remove barriers to enable more insights and discoveries

SAN DIEGO, Oct. 24, 2024 /PRNewswire/ -- Illumina, Inc. (NASDAQ: ILMN), a global leader in DNA sequencing and array-based technologies, today unveiled its MiSeqâ„¢ i100 Series of sequencing systems, delivering unparalleled benchtop speed and simplicity to advance next-generation sequencing (NGS) for labs.

The two new benchtop instruments, MiSeq i100 and MiSeq i100 Plus Systems, will empower customers to unlock powerful insights through an affordable, comprehensive solution that is simple to understand and use, even for those with limited NGS expertise. Room-temperature storage and shipping enable labs to sequence on demand, with no delays for thaw time, and same-day sample-to-analysis.

"Our customers told us they need a faster, smaller, and easy-to-use instrument, and that's what we're delivering with the MiSeq i100," said Jacob Thaysen, PhD, CEO of Illumina. "Whether you are an established next-generation sequencing lab, or looking to start sequencing for the first time, our latest benchtop instrument adds the plug-and-play flexibility that today's labs are seeking."

The MiSeq i100 Series builds on the legacy of the original benchtop MiSeq System, which Illumina customers have used since 2011 to power a host of genomic discoveries. Completely redesigned and incorporating the groundbreaking technology and chemistry of the NovaSeqâ„¢ X Series, the MiSeq i100 will help to fuel the next era of genomics growth and discovery.  

Key technology enhancements

The MiSeq i100 Series brings Illumina's powerful XLEAP-SBS™ chemistry innovation even further—for the first time, harnessing the potential of room-temperature storage and shipping, which provides customers greater flexibility in how they plan and execute their projects while reducing their environmental impact. It offers flexible output capabilities and comes in two configurations: the MiSeq i100 Plus System has the full 100 million single-end reads per run, and the MiSeq i100 System has a maximum of 25 million single-end reads per run. Key features include:

  • Room-temperature shipping and storage for reagents: Eliminating the cold chain and allowing for greater flexibility to sequence on demand without the need to thaw reagents, which is critical for running urgent samples
  • Sustainability: An 85% reduction in packaging waste compared to the MiSeq System supports a lower carbon footprint
  • Speed: Dramatic reduction in run times: as fast as four hours, with same-day results (4× faster than MiSeq)
  • Cost efficiency: Cost-effective consumables enable more affordable sequencing
  • Turnkey workflows: 18 proven end-to-end workflows across 10 applications
  • Simplicity: Simpler, streamlined operations for various levels of sequencing experience

Push-button workflows on MiSeq i100 are available for small whole-genome sequencing for microbiology and targeted NGS panels for both infectious disease and oncology. Workflows provide metrics either directly on the instrument or via cloud-based DRAGENâ„¢ genomic data analysis, minimizing the need for bioinformatics expertise.

"The MiSeq i100 symbolizes Illumina's commitment to delivering total systems with complete workflows that allow our customers to accomplish more," said Steve Barnard, PhD, chief technology officer of Illumina. "With its enhanced speed, simplicity, scalability, and quality–and its intuitive user experience–the MiSeq i100 sets a new standard for benchtop sequencing."

Customer reactions

Illumina conducted early access testing of MiSeq i100 with customers around the world. Geneviève DonPierre, team leader of NGS Sequencing at Génome Québec, shared her lab's experience with the instrument, noting that most of the sequencing operations at the Center of Expertise and Services of Génome Québec are conducted on the NovaSeq X Plus. "With this new instrument, we are able to provide answers quickly for small projects or for researchers who need fast answers to determine whether or not they should pursue their project." 

Génome Québec is a nonprofit organization that provides genomic services for researchers in the academic and industrial fields of 45 countries. DonPierre noted the importance of room temperature storage for her lab: "It really helps the planning for the sequencing run. We don't have to think two days before to get a kit out of the freezer. So it really is a game changer to have kits stored at room temperature."

Tim Roloff Handschin, PhD, co-leader of Microbial Genomics (NGS) at the Institute for Medical Microbiology at the University of Zurich, and his team conduct research on developing new diagnostic tests, antimicrobial resistance and antimicrobial drugs. In his lab's experience with MiSeq i100, the ease of use and being able to achieve a turnaround time from bacterial culture to results within 24 hours will be transformative.

"We can start two runs on the same day and thereby increase our sample flow massively. And given that the reagents are shipped at room temperature, we don't need to wait for the cartridges to thaw," Roloff said. "We can just launch a run whenever we're ready with a new pool and there is no planning needed upfront. This gives us great flexibility, and this can provide new possibilities to develop new tests."

The new instrument was unveiled during a virtual customer event; a replay may be viewed here. The MiSeq i100 will be available to ship globally in 2025. For more information, visit the website.

Use of forward-looking statements

This release may contain forward-looking statements that involve risks and uncertainties. Among the important factors to which our business is subject that could cause actual results to differ materially from those in any forward-looking statements are: (i) challenges inherent in developing, manufacturing, and launching new products and services; (ii) our ability to manufacture robust instrumentation and consumables; (iii) customer uptake of, and satisfaction with new products and services; and (iv) the speed and scale of new product adoption by customers, together with other factors detailed in our filings with the Securities and Exchange Commission, including our most recent filings on Forms 10-K and 10-Q, or in information disclosed in public conference calls, the date and time of which are released beforehand. We undertake no obligation, and do not intend, to update these forward-looking statements, to review or confirm analysts' expectations, or to provide interim reports or updates on the progress of the current quarter.

About Illumina

Illumina is improving human health by unlocking the power of the genome. Our focus on innovation has established us as a global leader in DNA sequencing and array-based technologies, serving customers in the research, clinical, and applied markets. Our products are used for applications in the life sciences, oncology, reproductive health, agriculture, and other emerging segments. To learn more, visit illumina.com and connect with us on X, Facebook, LinkedIn, Instagram, TikTok, and YouTube.

** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **

Illumina introduces the MiSeq i100 Series: its simplest, fastest benchtop sequencers

Illumina introduces the MiSeq i100 Series: its simplest, fastest benchtop sequencers

Global fans to experience the Games of the Future like never before as MOBA PC.Dota 2 competition kickoffs in Abu Dhabi

DUBAI, UAE, Dec. 13, 2025 /PRNewswire/ -- Phygital International, the global promoter of phygital sports, today announces the official launch of the GOTF OTT Platform, the dedicated streaming destination for the Games of the Future 2025 Abu Dhabi powered by ADNOC (GOTF 2025). The platform goes live as this year's competition begins, with its first broadcast featuring the opening rounds of the MOBA PC.Dota 2 discipline on 14 December from Pixoul Gaming in Abu Dhabi.

Accessible at https://tv.gofuture.games, the new streaming hub serves as the central digital home for live broadcasts, full-event replays, highlights, and exclusive behind-the-scenes content spanning all GOTF 2025 disciplines.

Designed for global accessibility and year-round engagement, the platform enables fans everywhere to watch every match live, revisit full replays at any time, and enjoy curated short-form content optimized for social and mobile viewing.

Powered end-to-end by technology partner Asport, the GOTF OTT Platform integrates advanced cloud-based broadcasting, seamless navigation, and real-time highlight creation tools to elevate the fan experience. These capabilities support richer storytelling across all channels and establish tv.gofuture.games as the long-term digital home of phygital sport.

Moba PC.Dota 2 competition to launch platform

The launch coincides with preparations for a spectacular start to the Games, as the MOBA PC.Dota 2 competition brings together iconic players, celebrated legends, and rising regional stars for what promises to be one of the most competitive line-ups in the event's history. All matches from the discipline will stream live on https://tv.gofuture.games.

Teams set to compete include E7, Paper Tigers, Legends Rebooted, Vikings, Team Phoenix, Nigma Galaxy, Win and TraBoTeam each bringing a distinctive mix of elite pro players and influential gaming personalities. One of the leading competitors will be Xu "BurNIng" Zhilei, who will be playing in team Paper Tigers and who iswidely regarded as one of the greatest carry players in Dota 2 history.

With such a stacked international field, fans can expect clashing playstyles, unpredictable upsets, and fresh rivalries, setting the stage for one of the headline showpieces of GOTF 2025.

Following the opening Group Stage, the competition advances into a full double-elimination playoff bracket, culminating in high-stakes best-of-three clashes on 18–19 December at ADNEC, where teams will fight for a place in the final and a shot at international glory.

Commenting on the launch of the platform, Nis Hatt, CEO of Phygital International, said: "The GOTF OTT Platform marks a major milestone in our mission to bring phygital sport to a global audience. This world-class digital destination showcases the energy, innovation, and inclusivity at the heart of the Games of the Future. As Dota 2 opens the competition tomorrow, we're excited to offer millions of fans a new way to experience every moment of this year's Games live."

Growing network of global broadcast partners 

In addition to the GOTF OTT Platform, fans can follow the Games of the Future Abu Dhabi 2025 powered by ADNOC across a growing network of international media rights and broadcast partners, ensuring fans around the world can catch all the action.

In the United States, coverage will be available via ESR TV, the leading gaming and esports network reaching mainstream audiences through platforms such as Apple TV, Sling, and Amazon Prime Video Channels. Across Latin America, FOX Sports Mexico and Zapping will deliver both English and Spanish-language broadcasts across the region.

On mobile-first platforms, Bigo Live will act as an interactive real-time streaming hub, offering live competition windows, creator-led co-streams, and fan-generated reactions. With strong Gen-Z and global creator adoption, Bigo Live brings the Games directly into participatory viewing culture. Complementing this, Likee will amplify the emotion and energy of GOTF 2025 through short-form video storytelling, transforming standout moments into shareable narratives.

These partners build on an already confirmed broadcast footprint that includes Sportworld and BIGG TV across EMEA, Huya and SOOP in Asia, and StarTimes and TV BRICS across Africa.

"With these major additions to our broadcast network, we take great pride in ensuring the Games of the Future Abu Dhabi 2025 powered by ADNOC are accessible to audiences worldwide. We are delivering a multi-regional, multi-generational platform that matches the scale and innovation of phygital sport," added Hatt.

Tickets for the Games of the Future Abu Dhabi 2025 powered by ADNOC are now on sale at www.gotfabudhabi.com. Fans can also follow all the latest updates and behind-the-scenes content on Instagram at @gamesofthefutureofficial and @gotfabudhabi.

About Phygital International (PI): 
Phygital International is the promoter of phygital sports globally and is focused on innovating and redefining sports. It is the custodian and rights holder of the Games of the Future and oversees the bidding process for each host city.

For further information please visit: https://Phygitalinternational.com   

About the Games of the Future (GOTF): 
The Games of the Future is an annual international event that fuses the worlds of physical and digital and is the pinnacle of phygital sport. The tournament brings together the next generation of phygital sporting heroes from all over the world to compete in a diverse range of phygital disciplines and challenges. The Games of the Future 2025 will be held in Abu Dhabi, UAE while the Games of the Future 2026, will be held in Astana, Kazakhstan.

For more information please visit: https://gofuture.games/ 

Contact: press@phygitalinternational.com 

 

 

Global fans to experience the Games of the Future like never before as MOBA PC.Dota 2 competition kickoffs in Abu Dhabi

DUBAI, UAE, Dec. 13, 2025 /PRNewswire/ -- Phygital International, the global promoter of phygital sports, today announces the official launch of the GOTF OTT Platform, the dedicated streaming destination for the Games of the Future 2025 Abu Dhabi powered by ADNOC (GOTF 2025). The platform goes live as this year's competition begins, with its first broadcast featuring the opening rounds of the MOBA PC.Dota 2 discipline on 14 December from Pixoul Gaming in Abu Dhabi.

Accessible at https://tv.gofuture.games, the new streaming hub serves as the central digital home for live broadcasts, full-event replays, highlights, and exclusive behind-the-scenes content spanning all GOTF 2025 disciplines.

Designed for global accessibility and year-round engagement, the platform enables fans everywhere to watch every match live, revisit full replays at any time, and enjoy curated short-form content optimized for social and mobile viewing.

Powered end-to-end by technology partner Asport, the GOTF OTT Platform integrates advanced cloud-based broadcasting, seamless navigation, and real-time highlight creation tools to elevate the fan experience. These capabilities support richer storytelling across all channels and establish tv.gofuture.games as the long-term digital home of phygital sport.

Moba PC.Dota 2 competition to launch platform

The launch coincides with preparations for a spectacular start to the Games, as the MOBA PC.Dota 2 competition brings together iconic players, celebrated legends, and rising regional stars for what promises to be one of the most competitive line-ups in the event's history. All matches from the discipline will stream live on https://tv.gofuture.games.

Teams set to compete include E7, Paper Tigers, Legends Rebooted, Vikings, Team Phoenix, Nigma Galaxy, Win and TraBoTeam each bringing a distinctive mix of elite pro players and influential gaming personalities. One of the leading competitors will be Xu "BurNIng" Zhilei, who will be playing in team Paper Tigers and who iswidely regarded as one of the greatest carry players in Dota 2 history.

With such a stacked international field, fans can expect clashing playstyles, unpredictable upsets, and fresh rivalries, setting the stage for one of the headline showpieces of GOTF 2025.

Following the opening Group Stage, the competition advances into a full double-elimination playoff bracket, culminating in high-stakes best-of-three clashes on 18–19 December at ADNEC, where teams will fight for a place in the final and a shot at international glory.

Commenting on the launch of the platform, Nis Hatt, CEO of Phygital International, said: "The GOTF OTT Platform marks a major milestone in our mission to bring phygital sport to a global audience. This world-class digital destination showcases the energy, innovation, and inclusivity at the heart of the Games of the Future. As Dota 2 opens the competition tomorrow, we're excited to offer millions of fans a new way to experience every moment of this year's Games live."

Growing network of global broadcast partners 

In addition to the GOTF OTT Platform, fans can follow the Games of the Future Abu Dhabi 2025 powered by ADNOC across a growing network of international media rights and broadcast partners, ensuring fans around the world can catch all the action.

In the United States, coverage will be available via ESR TV, the leading gaming and esports network reaching mainstream audiences through platforms such as Apple TV, Sling, and Amazon Prime Video Channels. Across Latin America, FOX Sports Mexico and Zapping will deliver both English and Spanish-language broadcasts across the region.

On mobile-first platforms, Bigo Live will act as an interactive real-time streaming hub, offering live competition windows, creator-led co-streams, and fan-generated reactions. With strong Gen-Z and global creator adoption, Bigo Live brings the Games directly into participatory viewing culture. Complementing this, Likee will amplify the emotion and energy of GOTF 2025 through short-form video storytelling, transforming standout moments into shareable narratives.

These partners build on an already confirmed broadcast footprint that includes Sportworld and BIGG TV across EMEA, Huya and SOOP in Asia, and StarTimes and TV BRICS across Africa.

"With these major additions to our broadcast network, we take great pride in ensuring the Games of the Future Abu Dhabi 2025 powered by ADNOC are accessible to audiences worldwide. We are delivering a multi-regional, multi-generational platform that matches the scale and innovation of phygital sport," added Hatt.

Tickets for the Games of the Future Abu Dhabi 2025 powered by ADNOC are now on sale at www.gotfabudhabi.com. Fans can also follow all the latest updates and behind-the-scenes content on Instagram at @gamesofthefutureofficial and @gotfabudhabi.

About Phygital International (PI): 
Phygital International is the promoter of phygital sports globally and is focused on innovating and redefining sports. It is the custodian and rights holder of the Games of the Future and oversees the bidding process for each host city.

For further information please visit: https://Phygitalinternational.com   

About the Games of the Future (GOTF): 
The Games of the Future is an annual international event that fuses the worlds of physical and digital and is the pinnacle of phygital sport. The tournament brings together the next generation of phygital sporting heroes from all over the world to compete in a diverse range of phygital disciplines and challenges. The Games of the Future 2025 will be held in Abu Dhabi, UAE while the Games of the Future 2026, will be held in Astana, Kazakhstan.

For more information please visit: https://gofuture.games/ 

Contact: press@phygitalinternational.com 

 

 

** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **

Official streaming platform for the Games of the Future Abu Dhabi 2025 powered by ADNOC launches ahead of opening competition

Official streaming platform for the Games of the Future Abu Dhabi 2025 powered by ADNOC launches ahead of opening competition

Official streaming platform for the Games of the Future Abu Dhabi 2025 powered by ADNOC launches ahead of opening competition

Official streaming platform for the Games of the Future Abu Dhabi 2025 powered by ADNOC launches ahead of opening competition

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