TOKYO--(BUSINESS WIRE)--Apr 17, 2025--
Rigaku Corporation, a Group company of Rigaku Holdings Corporation (headquarters: Akishima, Tokyo; CEO: Jun Kawakami; hereinafter “Rigaku”), and SPERA PHARMA, Inc. (headquarters: Osaka; President & Representative Director: Keitaro Iwaki; hereinafter “SPERA PHARMA”) have initiated a strategic partnership aimed at accelerating and transforming pharmaceutical development by leveraging the two companies’ cutting-edge technologies and extensive expertise.
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SPERA PHARMA will use XtaLAB Synergy-ED, an integrated platform for electronic diffraction provided by Rigaku, for contract analytical services, thereby offering customers robust support in pharmaceutical development.
The XtaLAB Synergy-ED incorporates 3D ED/MicroED 1, which is utilized for the structure analysis of substances, including microscopic crystals and minute quantities of crystalline powder. This sophisticated technology provides sufficiently high resolution to determine atomic-level structures, enabling the detailed elucidation of molecular structures of organic compounds and similar substances.
SPERA PHARMA is currently the world’s only company in the pharmaceutical industry offering contract analytical services with the XtaLAB Synergy-ED. Rigaku will extend technical support to SPERA PHARMA for its contract analytical operations.
Furthermore, the two companies are collaborating closely to advance research utilizing the XtaLAB Synergy-ED and to actively share information on the application methods and analytical technologies.
Through this partnership, Rigaku and SPERA PHARMA aim to provide robust support at the forefront of pharmaceutical development, playing pivotal roles in pioneering the future of medicine.
1: Stands for “Three-Dimensional Electron Diffraction/Microcrystal Electron Diffraction.” A method for analysis of crystalline structures using electronic diffraction.
Example of Joint Research and Use
“Detection of Hydrogen Atoms Using Only 3D ED/MicroED and Contribution to Structure Determining Salts or Cocrystals,” Crystal Growth ＆ Design, 2025, 25, 1, 129–135
URL: https://pubs.acs.org/doi/10.1021/acs.cgd.4c01421
(Registration required to read.)
About the Rigaku Group
Since its establishment in 1951, the engineering professionals of the Rigaku group have been dedicated to benefiting society with leading-edge technologies, notably including its core fields of X-ray and thermal analysis. With a market presence in over 90 countries and some 2,000 employees from 9 global operations, Rigaku is a solution partner in industry and research analysis institutes. Our overseas sales ratio has reached approximately 70% while sustaining an exceptionally high market share in Japan. Together with our customers, we continue to develop and grow. As applications expand from semiconductors, electronic materials, batteries, environment, resources, energy, life science to other high-tech fields, Rigaku realizes innovations “To Improve Our World by Powering New Perspectives.”
For details, please visit rigaku-holdings.com/english
About SPERA PHARMA
SPERA PHARMA was established in July 2017 in the Juso area of Yodogawa-ku, Osaka. It is a contract development and manufacturing organization (CDMO) specializing in Chemistry, Manufacturing and Controls (CMC) pharmaceutical sciences, including process chemistry, formulation development, and analytical development, as well as the manufacturing of investigational drugs. The company’s expert research team, which has extensive experience and proven results, works flexibly in all phases of pharmaceutical development from the early stage to final drug application. SPERA PHARMA is a one-stop provider of comprehensive services and solutions to meet customer needs. For further information, please visit spera-pharma.co.jp/en
Left: Keitaro Iwaki, President & Representative Director, SPERA PHARMA; Right: Jun Kawakami, President & CEO, Rigaku
President Vladimir Putin visited Russia's Kursk region for the first time since Moscow claimed that it drove Ukrainian forces out of the area last month, the Kremlin said Wednesday.
Putin visited the region bordering Ukraine the previous day, according to the Kremlin.
Ukrainian forces made a surprise incursion into Kursk in August 2024 in one of its biggest battlefield successes in the more than three-year war. The incursion was the first time Russian territory was occupied by an invader since World War II and dealt a humiliating blow to the Kremlin.
Since the end of 2023, Russia has mostly had the advantage on the battlefield, with the exception of Kursk.
Ukraine, the U.S. and South Korea said that North Korea sent up to 12,000 troops to help the Russian army take back control of Kursk, and Russia said on April 26 that its forces had pushed out the Ukrainian army. Kyiv officials denied the claim.
Putin’s unannounced visit appeared to be an effort to show Russia is in control of the conflict — even though its full-scale invasion of its neighbor has been slow and costly in terms of casualties and equipment — amid recent U.S. and European proposals for a ceasefire that Putin has effectively rejected.
Video broadcast by Russian state media showed that Putin visited Kursk Nuclear Power Plant-2, which is still under construction, and met with selected volunteers behind closed doors.
Many of the volunteers wore clothes emblazoned with the Russian flag and the Latin letters “Z” and “V”, which are symbols of Russia’s invasion of Ukraine.
“What you are doing now during this difficult situation for this region, for this area, and for the country, will remain with you for the rest of your life as, perhaps, the most meaningful thing with which you were ever involved,” Putin said as he drank tea with the volunteers.
Ukraine's surprise thrust into Kursk and its ability to hold land there was a logistical feat, carried out in secrecy, that countered months of gloomy news from the front about Ukrainian forces being pushed backward by the bigger Russian army.
Kyiv's strategy aimed to show that Russia has weaknesses and that the war isn't lost. It also sought to distract Russian forces from their onslaught in the eastern Donetsk region of Ukraine.
The move was fraught with risk. Analysts noted that it could backfire and open a door for Russian advances in Ukraine by further stretching Ukrainian forces that are short-handed along the roughly 1,000-kilometer (620-mile) front line.
The incursion didn’t significantly change the dynamics of the war.
Putin told acting Gov. Alexander Khinshtein that the Kremlin supported the idea of continuing monthly payments to displaced families that still couldn't return to their homes.
Putin said that he would back a proposal to build a museum in the region to celebrate what acting Gov. Alexander Khinshtein described as “the heroism of our defenders and the heroism of the region’s residents.”
Disgruntled residents had previously shown their disapproval over a lack of compensation in rare organized protests.
Russia’s Ministry of Defense said that its air defenses shot down 159 Ukrainian drones across the country overnight, including 53 over the Oryol region and 51 over the Bryansk region.
In Ukraine, Russian drone attacks killed two people and wounded five others in the northern Sumy region, the regional administration said.
In the Kyiv region, four members of a family were injured when debris from a downed drone hit their home, according to the regional administration.
Russia launched 76 Shahed and decoy drones overnight at Ukraine, the Ukrainian air force said.
Follow AP’s coverage of the war in Ukraine at https://apnews.com/hub/russia-ukraine
In this photo released by the Russian Presidential Press Service on Wednesday, May 21, 2025, Russian President Vladimir Putin, 2nd left, attends a meeting with volunteers at Kursk region, Russia. (Russian Presidential Press Service via AP)
In this photo released by the Russian Presidential Press Service on Wednesday, May 21, 2025, Russian President Vladimir Putin, center, speaks with volunteers at Kursk region, Russia. (Russian Presidential Press Service via AP)
In this photo taken from video distributed by Russian Defense Ministry Press Service on Wednesday, May 21, 2025, Russian servicemen attend a combat training for assault units in an undisclosed location in Ukraine. (Russian Defense Ministry Press Service via AP)
