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Asia's First Real-World ctDNA-MRD Study Strengthens Evidence for Cost-Effective Cancer Monitoring

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Asia's First Real-World ctDNA-MRD Study Strengthens Evidence for Cost-Effective Cancer Monitoring
Business

Business

Asia's First Real-World ctDNA-MRD Study Strengthens Evidence for Cost-Effective Cancer Monitoring

2025-04-19 19:45 Last Updated At:20:05

A landmark study recently published in March 2025 by JCO Oncology Advances, demonstrates the potential of K-TRACKTM in monitoring treatment response and assessing recurrence risk among 623 Solid-Tumor Patients of six cancer types (lung, colorectal, breast, gastric, liver, or ovarian cancer).(1)

SINGAPORE, April 19, 2025 /PRNewswire/ -- Gene Solutions, a biotechnology company dedicated to advancing precision oncology in Asia, is excited to announce the publication of a pioneering real-world study in JCO Oncology Advances, validating circulating tumor DNA (ctDNA) as a strong prognostic biomarker to effectively monitor patients during cancer management.

K-TRACKTM is a breakthrough in affordable tumor profiling and personalized cancer monitoring leveraging ctDNA technology. The study, the first of its kind in Asia, confirms K-TRACKTM's clinical value across both early and advanced stages of cancer. The test can detect residual cancer cells (Minimal Residual Disease – MRD) after radical treatment, predict recurrence months earlier than traditional methods, and monitor treatment responses effectively. This innovative dual assay offers hope to patients in underserved regions where access to advanced diagnostic technologies remains a challenge.

Asia represents nearly 50% of global cancer cases, with incidence rates rising at an alarming pace. While some developed markets in the region have seen improvements in cancer mortality rates, Southeast Asia continues to experience high death rates, predominantly driven by cancer recurrence. (2,3)

Research has demonstrated the clinical prognostic value of ctDNA in a variety of cancer types both before and after treatment  (4).  Despite this potential, the adoption of ctDNA testing remains limited due to factors such as high costs, the absence of standardized methods and insufficient clinical utility of real-world data.

K-TRACKTM was developed as an affordable, reliable personalized test for monitoring ctDNA across multiple solid tumors. It is designed to facilitate early detection of cancer recurrence and provide real-time monitoring of treatment responses. Validated in both clinical trials and real-world studies, K-TRACKTM is built for meaningful impact in cancer care while ensuring accessibility. Here's how we make it work:

Real-world monitoring of ctDNA has proven effective in predicting early cancer recurrence, allowing for timely interventions and improved patient outcomes. In both early and advanced-stage cancer patients, K-TRACKTM has demonstrated high accuracy in predicting recurrence. Following surgery, 84.4% [CA1]  of patients with ctDNA-positive results eventually relapsed, while an impressive 96.3% [CA2]  of those with ctDNA-negative results remained cancer-free. Moreover, the test could detect relapse up to 5.5-19.5 months earlier than clinical diagnosis by imaging methods. Simultaneously, the six case studies presented illustrated the clinical utility of ctDNA monitoring in predicting treatment response, informing adjuvant chemotherapy decisions, and identifying new resistant mutations to current targeted treatment. Thus, empowering clinicians with real-time, actionable insights to inform treatment decisions.

A Vision for Equitable Care

"Access to cutting-edge, personalized cancer treatment and monitoring—based on tumor genomic profiling— too often depends on where you live or what you can afford," said Dr. Lan N. Tu, Principal Investigator at Gene Solutions. "Our mission with K-TRACKTM is to close that gap by providing an affordable and precise real-time solution for routine clinical use."

Gene Solutions is actively investing in two key areas:

1. On-going Clinical Trials and Real-World Studies:

The company is conducting comprehensive research to validate the role of ctDNA across various cancer types and treatment stages. This includes evaluating responses to TKIs and immune checkpoint inhibitors (ICIs) in lung cancer, neoadjuvant therapy in breast cancer, total neoadjuvant therapy in rectal cancer, and the use of biomarkers to inform immunotherapy treatment decisions in advanced cancers.

2. Biopharma Collaborations:

Gene Solutions is actively pursuing partnerships with biopharmaceutical companies to provide innovative solutions aimed at accelerating drug development across a range of therapeutic modalities. As the scientific evidence supporting ctDNA continues to grow, Gene Solutions is committed to expanding its research and fostering collaborations with current and new partners to explore new applications in cancer care. The company's direction aligns with the FDA's recommendation on ctDNA use as a biomarker in the development of curative-intent therapies for solid tumors which states: "ctDNA as a biomarker has a number of potential regulatory and clinical uses in the early-stage setting that may assist and expedite drug development." (5)

About Gene Solutions

Gene Solutions, a multinational biotech company in Asia, is leading the way in leveraging advanced AI and ctDNA technologies for innovative cancer detection solutions. The company partners with over 4,500 hospitals and clinics across Southeast Asia and employs a dedicated team of approximately 250 biology experts and technicians out of a total of 700 employees.

With more than 50 peer-reviewed publications and over 50 multi-center studies conducted across the region, Gene Solutions is recognized for its proprietary research and CAP-accredited next-generation sequencing (NGS) laboratories in Singapore and Vietnam. By integrating multi-dimensional genomics with AI-driven methodologies, the company is committed to transforming cancer care and improving patient outcomes.

** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **

Asia's First Real-World ctDNA-MRD Study Strengthens Evidence for Cost-Effective Cancer Monitoring

Asia's First Real-World ctDNA-MRD Study Strengthens Evidence for Cost-Effective Cancer Monitoring

Asia's First Real-World ctDNA-MRD Study Strengthens Evidence for Cost-Effective Cancer Monitoring

Asia's First Real-World ctDNA-MRD Study Strengthens Evidence for Cost-Effective Cancer Monitoring

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Introducing Motorola's stunning new motorola edge 60 fusion

2025-05-16 14:15 Last Updated At:14:35

Packed with premium features: s marter, highly personalised AI;
world-first camera features; Pantone Validated Colours and
the brightest display in the category - all for just $699

SYDNEY, May 16, 2025 /PRNewswire/ -- Mobile communications leader, Motorola, has announced the launch of the highly anticipated motorola edge 60 fusion in Australia.

On sale from Thursday 22 May, the motorola edge 60 fusion introduces new highly evolved moto ai[12] features which are more intuitive than any previous models and set to transform daily interactions. With the world's first Sony LYTIATM 700C camera validated by Pantone, plus the brightest display in the category[1] with Pantone Validated Colours[10], it produced the most outstanding, true-to-life imagery. The battery can power up for a full-day battery in just eight minutes . 

Priced at just $699, the motorola edge 60 fusion features a tactile leather-inspired finish for an added layer of elegance. The colours of Slipstream, Amazonite and Zephyr have been designed in conjunction with Pantone Colour InstituteTM.  

Corning® Gorilla® Glass 7i protects the device with 2x better drop and scratch performance[7]. It also meets military standards for durability - ideal to face scorching summer days as high as 60°C - even blazing temperatures inside a parked car! It also withstands up to 95% humidity, the kind found in coastal areas[8]. Its worry-free underwater protection is designed to withstand submersion in up to 1.5 meters of fresh water for 30 minutes, so being dropped in the water is one less thing to worry about[9].

FULL TECH SPECS:

Everyday moments made easier with moto ai

Artificial Intelligence is central to Motorola's innovation, enhancing all facets of its technology. With a quick prompt like 'Catch me up' moto ai delivers concise, tailored summaries[5] of what matters most. Users can skip the endless scrolling and focus on staying on top of their day with clarity and ease. Expanded app coverage – including WhatsApp calls – and customisable summaries put the user in control, while quick actions like returning calls or replying to messages make staying connected easy.

Capturing screenshots, photos, and notes is easy with moto ai's 'Remember this and Recall' automatically analysing and tagging them. If you need more detail, add a note yourself. Later, simply ask, "What was I getting for Dad?" and moto ai will pull up exactly what's needed, like that screenshot of a polo shirt.

Users can stay focused with moto ai's 'Pay attention', allowing moto ai to handle the notes. With live transcription and speaker identification, type or press 'Pay Attention' in the search bar to start recording automatically. Your session is transcribed in real time, so you can stay engaged without missing a word.

Motorola hasn't just strengthened its existing moto ai features, but equipped the edge 60 fusion with new AI capabilities that will transform daily interactions: Next Move, Playlist Studio, and Image Studio.

With Motorola's Next Move, users can receive tailored recommendations based on what's on their screen, whether a recipe or travel plans, moto ai gives suggested next steps - ideal for beginners and AI enthusiasts alike who want to understand what AI can do for them.

Users can turn to Playlist Studio to set the tone for the day, using on-screen content or a prompt within the moto ai app to curate a perfect playlist, while Image Studio[11] helps bring fresh entertainment to group chats and social media, using generative AI creation and editing capabilities to turn ideas into images, avatars, stickers, and wallpapers.

Content creation continues to be an area significantly enhanced by moto ai, bringing a cinematic effect to everyday moments, moto ai works behind the scenes to deliver the best possible photos and videos. The Photo Enhancement Engine applies precise colour, brightness, and texture adjustments, as well as noise reduction to content captured, bringing it to life with exceptional clarity and vibrancy.

Smartphone essentials engineered with the premium quality you want 

The motorola edge 60 fusion offers the best of the best when it comes to essential features. The camera is not just a first for Motorola, but the world, powered by Sony LYTIATM 700C sensor and featuring OIS video stabilisation, users can effortlessly shoot like a pro and curate standout photos. With colours validated by Pantone, users can be confident that they are documenting the world as they see it, true to life. 

Impressive imagery requires an impressive display, and the motorola edge 60 fusion delivers Motorola's sharpest, brightest display ever. The 6.7" pOLED display reveals the full potential of content, even in particularly sunny environments. Users can enjoy a clear, vibrant picture with Pantone Validated Colours[10], plus sharper detail and less pixelation thanks to Super HD resolution (1220p), delivering 13% more resolution than standard Full HD (1080p) displays. In addition, it can reach a peak brightness of up to 4500 nits – 2.8x brighter than the previous generation motorola edge[3,4]

These groundbreaking essentials require an impressive battery to support, and Motorola has delivered just that with a 5200mAh battery and 68W TurboPowerTM charging, allowing users to power up for a full-day battery in just eight minutes[2]

From its exceptional camera, to the stunning display, all can be enjoyed stutter-free, with the ultrafast MediaTek Dimensity 7300 chipset ensuring no annoying stops and starts, plus up to additional 12GB of RAM[9] with RAM Boost. 

Twice as tough: Durability and craftsmanship like never before 

The motorola edge 60 fusion is the epitome of quality craftsmanship and purposeful design, featuring a leather-inspired finish that gives you a touch of luxury and an added layer of elegance. In another example of maximising Motorola's unique partnership with Pantone, the device's aesthetic is elevated further thanks to specially curated hues - Slipstream, Amazonite and Zephyr - that have been designed in conjunction with Pantone Colour InstituteTM.

Its beautiful finish is built to last, featuring Corning® Gorilla® Glass 7i, the device's display is protected with 2x better drop and scratch performance[7]. The motorola edge 60 fusion also meets military standards for durability, thanks to its MIL-STG 810H rating, all while maintaining a sophisticated, elegant look-and-feel. It's protected against extreme temperatures including harsh winters as cold as -20°C or scorching summer days as high as 60°C - even the blazing temperatures inside a parked car. It also withstands up to 95% humidity, the kind found in coastal areas[8]

Complementing its tough build is its worry-free underwater protection. The motorola edge 60 fusion is engineered to give you peace of mind with IP68 and IP69 ratings, offering superior protection against dust, direct, sand, and high-pressure water. Plus, it's designed to withstand submersion in up to 1.5 meters of fresh water for 30 minutes, so being dropped in the water is one less thing to worry about[9]

Availability

The motorola edge 60 fusion is available to buy from 22 May, RRP $699. Stockists will include JB Hi-Fi, Harvey Norman, Officeworks, The Good Guys, Amazon, and motorola.com.au. Colour availability may vary store-to-store.

Visit motorola.com.au to sign up for updates.

Follow Motorola Australia on FacebookInstagram and TikTok.

Legal disclaimers

** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **

Introducing Motorola's stunning new motorola edge 60 fusion

Introducing Motorola's stunning new motorola edge 60 fusion

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