TORONTO (AP) — Alejandro Kirk hit a game-ending, bases-loaded single in the 10th inning and the Toronto Blue Jays overcame a six-run deficit to beat the Boston Red Sox 7-6 in Lucas Giolito's return on Wednesday night, stopping a three-game losing streak.
Vladimir Guerrero Jr. started the 10th as the automatic runner on second, Justin Slaten (0-1) intentionally walked Daulton Varsho and George Springer with one out and Kirk singled to left.
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Toronto Blue Jays' Bo Bichette, left, leads off first base as Boston Red Sox starting pitcher Lucas Giolito (54) throws in the first inning of a baseball game in Toronto on Wednesday, April 30, 2025. (Jon Blacker/The Canadian Press via AP)
Boston Red Sox starting pitcher Lucas Giolito (54) throws to a Toronto Blue Jays batter in the first inning of a baseball game in Toronto on Wednesday, April 30, 2025. (Jon Blacker/The Canadian Press via AP)
Boston Red Sox starting pitcher Lucas Giolito (54) throws to a Toronto Blue Jays batter in first inning American League baseball action in Toronto on Wednesday, April 30, 2025. (Jon Blacker/The Canadian Press via AP)
Boston Red Sox's Carlos Narvaez (75) celebrates hitting a solo home run against the Toronto Blue Jays in sixth inning American League baseball action in Toronto on Wednesday, April 30, 2025. (Jon Blacker/The Canadian Press via AP)
Toronto Blue Jays' Vladimir Guerrero Jr, left, and Anthony Santander (25) celebrate after Santander hit a three-run home run against the Boston Red Sox in seventh inning American League baseball action in Toronto on Wednesday, April 30, 2025. (Jon Blacker/The Canadian Press via AP)
Toronto Blue Jays' Anthony Santander (25) runs the bases after hitting a three-run home run against the Boston Red Sox in seventh inning American League baseball action in Toronto on Wednesday, April 30, 2025. (Jon Blacker/The Canadian Press via AP)
Toronto Blue Jays' Alejandro Kirk (30) hits a walk-off RBI single in tenth inning American League baseball action to defeat the Boston Red Sox in Toronto on Wednesday, April 30, 2025. (Jon Blacker/The Canadian Press via AP)
Toronto Blue Jays' Alejandro Kirk (30) hits a walk-off RBI single in tenth inning American League baseball action to defeat the Boston Red Sox in Toronto on Wednesday, April 30, 2025. (Jon Blacker/The Canadian Press via AP)
Toronto Blue Jays' Alejandro Kirk, centre facing, celebrates with teammates after hitting a walk-off RBI single in tenth inning American League baseball action to defeat the Boston Red Sox in Toronto on Wednesday, April 30, 2025. (Jon Blacker/The Canadian Press via AP)
Toronto Blue Jays' Alejandro Kirk (30) runs to first base after hitting a walk-off RBI single in tenth inning American League baseball action to defeat the Boston Red Sox in Toronto on Wednesday, April 30, 2025. (Jon Blacker/The Canadian Press via AP)
Jeff Hoffman (3-0) struck out three in two hitless innings.
Anthony Santander tied the score in the seventh with his fourth home run this season, a three-run drive off Garrett Whitlock.
Kirk and Varsho started the rebound from a 6-0 deficit with back-to-back homers in the sixth off Giolito, who made his Red Sox debut more than 15 months after signing a a $38.5 million. two-year contract, Giolito didn’t pitch last season because of a partial tear in his right ulnar collateral ligament, then had been sidelined since spring training due to a strained left hamstring.
Toronto began the night with 16 homers, 29th among the 30 teams, and hit three homers in a game for the first time this season.
Yariel Rodríguez's run-scoring balk and Alex Bregman's seventh homer built a 2-0 lead in the first, and Jarren Duran hit an RBI single in the second and scored on Rafael Devers' double. Carlos Narváez stretched the lead to 6-0 with a two-run homer off Chad Green in the sixth.
Kirk lined a single over Jarren Duran to end the game.
Toronto scored more than four runs for the first time since a 6-3 win over Atlanta on April 15.
Red Sox RHP Tanner Houck (0-2, 7.58 ERA) is expected to start against Toronto RHP José Berríos (1-1, 4.24) on Thursday.
AP MLB: https://apnews.com/hub/mlb
Toronto Blue Jays' Bo Bichette, left, leads off first base as Boston Red Sox starting pitcher Lucas Giolito (54) throws in the first inning of a baseball game in Toronto on Wednesday, April 30, 2025. (Jon Blacker/The Canadian Press via AP)
Boston Red Sox starting pitcher Lucas Giolito (54) throws to a Toronto Blue Jays batter in the first inning of a baseball game in Toronto on Wednesday, April 30, 2025. (Jon Blacker/The Canadian Press via AP)
Boston Red Sox starting pitcher Lucas Giolito (54) throws to a Toronto Blue Jays batter in first inning American League baseball action in Toronto on Wednesday, April 30, 2025. (Jon Blacker/The Canadian Press via AP)
Boston Red Sox's Carlos Narvaez (75) celebrates hitting a solo home run against the Toronto Blue Jays in sixth inning American League baseball action in Toronto on Wednesday, April 30, 2025. (Jon Blacker/The Canadian Press via AP)
Toronto Blue Jays' Vladimir Guerrero Jr, left, and Anthony Santander (25) celebrate after Santander hit a three-run home run against the Boston Red Sox in seventh inning American League baseball action in Toronto on Wednesday, April 30, 2025. (Jon Blacker/The Canadian Press via AP)
Toronto Blue Jays' Anthony Santander (25) runs the bases after hitting a three-run home run against the Boston Red Sox in seventh inning American League baseball action in Toronto on Wednesday, April 30, 2025. (Jon Blacker/The Canadian Press via AP)
Toronto Blue Jays' Alejandro Kirk (30) hits a walk-off RBI single in tenth inning American League baseball action to defeat the Boston Red Sox in Toronto on Wednesday, April 30, 2025. (Jon Blacker/The Canadian Press via AP)
Toronto Blue Jays' Alejandro Kirk (30) hits a walk-off RBI single in tenth inning American League baseball action to defeat the Boston Red Sox in Toronto on Wednesday, April 30, 2025. (Jon Blacker/The Canadian Press via AP)
Toronto Blue Jays' Alejandro Kirk, centre facing, celebrates with teammates after hitting a walk-off RBI single in tenth inning American League baseball action to defeat the Boston Red Sox in Toronto on Wednesday, April 30, 2025. (Jon Blacker/The Canadian Press via AP)
Toronto Blue Jays' Alejandro Kirk (30) runs to first base after hitting a walk-off RBI single in tenth inning American League baseball action to defeat the Boston Red Sox in Toronto on Wednesday, April 30, 2025. (Jon Blacker/The Canadian Press via AP)
This photo gallery features some of the top photos of the Dakar Rally in Saudi Arabia in the past week by AP photographer Thibault Camus. Nasser Al-Attiyah regained the lead in the rally after blasting the first all-sand stage of the race in the Saudi desert on Friday. Five-time champion Al-Attiyah dominated the second half of the 331-kilometer stage between Hail and Riyadh.
Rider Ricky Brabec competes during the seventh stage of the Dakar Rally between Riyadh and Wadi Ad Dawasir, Saudi Arabia, Sunday, Jan.11, 2026. (AP Photo/Thibault Camus)
Rider Luciano Benavides competes during the seventh stage of the Dakar Rally between Riyadh and Wadi Ad Dawasir, Saudi Arabia, Sunday, Jan.11, 2026. (AP Photo/Thibault Camus)
Driver Sebastien Loeb and co-driver Edouard Boulanger compete during the fourth stage of the Dakar Rally between Alula and Hail, Saudi Arabia, Wednesday, Jan. 7, 2026. (AP Photo/Thibault Camus)
Rider Arnau Lledo competes during the third stage of the Dakar Rally with a start and finish in Alula, Saudi Arabia, Tuesday, Jan. 6, 2026. (AP Photo/Thibault Camus)
Driver Carlos Sainz and co-driver Lucas Cruz compete during the second stage of the Dakar Rally between Yanbu and Alula, Saudi Arabia, Monday, Jan. 5, 2026. (AP Photo/Thibault Camus)
Driver Simon Vitse and co-driver Max Delfino compete during the sixth stage of the Dakar Rally between Hail and Riyadh, Saudi Arabia, Friday, Jan. 9, 2026. (AP Photo/Thibault Camus)
Spectators attend to the sixth stage of the Dakar Rally between Hail and Riyadh, Saudi Arabia, Friday, Jan. 9, 2026. (AP Photo/Thibault Camus)
Spectators watch driver Denis Krotov and co-driver Konstantin Zhiltsov competing during the sixth stage of the Dakar Rally between Hail and Riyadh, Saudi Arabia, Friday, Jan. 9, 2026. (AP Photo/Thibault Camus)
Driver Nani Roma changes a tire of his car at the end of the fourth stage of the Dakar Rally between Alula and Hail, Saudi Arabia, Wednesday, Jan. 7, 2026. (AP Photo/Thibault Camus)
Driver Mattias Ekstrom and co-driver Emil Bergkvist compete during the second stage of the Dakar Rally between Yanbu and Alula, Saudi Arabia, Monday, Jan. 5, 2026. (AP Photo/Thibault Camus)
Mechanic Filip Skrobanek eats after he stopped for a bivouac following the fourth stage of the Dakar Rally between Alula and Hail, Saudi Arabia, Wednesday, Jan. 7, 2026. (AP Photo/Thibault Camus)
Drivers and co-drivers pack up their tents before the start of the fifth stage of the Dakar Rally between Alula and Hail, Saudi Arabia, Thursday, Jan. 8, 2026. (AP Photo/Thibault Camus)
Driver Laia Sanz and co-driver Maurizio Gerini compete during the prologue of the Dakar Rally in Yanbu, Saudi Arabia, Saturday, Jan. 3, 2026. (AP Photo/Thibault Camus)
Rider Daniel Sanders drives beside camels during the second stage of the Dakar Rally between Yanbu and Alula, Saudi Arabia, Monday, Jan. 5, 2026. (AP Photo/Thibault Camus)
Rider Skyler Howes competes during the first stage of the Dakar Rally in Yanbu, Saudi Arabia, Sunday, Jan. 4, 2026. (AP Photo/Thibault Camus)
Driver Denis Krotov sits on a tire as co-driver Konstantin Zhiltsov, unseen, repairs their car after they stopped for a bivouac at the end of the fourth stage of the Dakar Rally between Alula and Hail, Saudi Arabia, Wednesday, Jan. 7, 2026. (AP Photo/Thibault Camus)
Driver Carlos Sainz and co-driver Lucas Cruz compete during the fourth stage of the Dakar Rally between Alula and Hail, Saudi Arabia, Wednesday, Jan. 7, 2026. (AP Photo/Thibault Camus)
Rider Luciano Benavides competes during the sixth stage of the Dakar Rally between Hail and Riyadh, Saudi Arabia, Friday, Jan. 9, 2026. (AP Photo/Thibault Camus)
Driver Jeremias Gonzalez Ferioli and co-driver Gonzalo Rinaldi compete during the third stage of the Dakar Rally with a start and finish in Alula, Saudi Arabia, Tuesday, Jan. 6, 2026. (AP Photo/Thibault Camus)