AROA hits evidence milestone with real-world study validating the efficacy of Endoform in treating challenging venous leg ulcers.

AUCKLAND, New Zealand, May 2, 2025 /PRNewswire/ -- Soft tissue regeneration company, Aroa Biosurgery, is pleased to announce a milestone in clinical evidence.

There are now over 100 peer-reviewed studies describing the efficacy of the company's proprietary AROA ECM technology.

AROA's most recent publication was a large retrospective analysis of real-world evidence (RWE) from wound care centers in the US, assessing the efficacy of the company's Endoform Natural^TM product in treating venous leg ulcers (VLUs), in comparison to a leading reconstituted collagen dressing.

VLU's are open sores that are hard-to-heal because of impaired blood flow and can be very debilitating and painful.  These types of wounds are difficult for clinicians to treat successfully. For example, only ~40% of VLUs can be healed after 3 months of treatment and there is a relatively high chance that these wounds will recur^[1].

The peer-reviewed study, entitled "Clinical Efficacy of Ovine Forestomach Matrix and Collagen/Oxidized Regenerated Cellulose for the Treatment of Venous Leg Ulcers: A Retrospective Comparative Real-World Evidence Study" was published in the open access journal 'International Wound Journal in April 2025.

The study compared 470 VLU's that had been treated with Endoform Natural to 360 VLU's that had been treated with a reconstituted collagen product. The study used existing data from 223 wound care centers with minimal inclusion or exclusion criteria so that 'real-world' use of both products could be compared.

"There is a growing awareness of RWE studies to validate clinical performance" says Chief Scientific Officer, Dr. Barnaby May. "These types of studies enable much larger patient numbers to be compared versus traditional randomized controlled trials. Given that RWE studies use data from 'real-world' use of a treatment, the results can be more meaningful, especially in wound care where there is a high degree of variability in how wounds are cared for and patient factors."

The study found that VLUs treated with Endoform Natural healed up to ~ 8 weeks faster versus the comparator group, and the chances of the wound healing were significantly improved when Endoform Natural was used as part of treatment.

The striking difference in the healing outcomes demonstrate the potential for considerable cost reductions and improvements in patient quality of life, due to the significant improvements seen when VLUs were treated using Endoform Natural.

Dr. Gregory Bohn MD was part of the research team. "I was first introduced to Endoform in 2012 and started using the product to treat my own patients with VLUs. This new data validates what I have seen in my own practice managing VLUs with Endoform."

This is the second large retrospective RWE comparing Endoform Natural to a leading reconstituted collagen dressing. A previous study included the analysis of over 2,200 diabetic foot ulcers (DFUs) and also demonstrated significantly faster healing of DFUs using Endoform Natural^[2].

The study is available online here.

[1] Kolluri R, Lugli M, Villalba L, Varcoe R, Maleti O, Gallardo F, et al. An estimate of the economic burden of venous leg ulcers associated with deep venous disease. Vasc Med. 2022;27(1):63-72.

[2] Bosque BA, Frampton C, Chaffin AE, Bohn GA, Woo K, DeLeonardis C, Lepow BD, Melin MM, Madu T, Dowling SG, May BCH. Retrospective real-world comparative effectiveness of ovine forestomach matrix and collagen/ORC in the treatment of diabetic foot ulcers. Int Wound J. 2022 May;19(4):741-753.

[1] Kolluri R, Lugli M, Villalba L, Varcoe R, Maleti O, Gallardo F, et al. An estimate of the economic burden of venous leg ulcers associated with deep venous disease. Vasc Med. 2022;27(1):63-72.

[2] Bosque BA, Frampton C, Chaffin AE, Bohn GA, Woo K, DeLeonardis C, Lepow BD, Melin MM, Madu T, Dowling SG, May BCH. Retrospective real-world comparative effectiveness of ovine forestomach matrix and collagen/ORC in the treatment of diabetic foot ulcers. Int Wound J. 2022 May;19(4):741-753.

** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **

AROA hits evidence milestone with real-world study validating the efficacy of Endoform in treating challenging venous leg ulcers.

Limited Edition Drop Features Iconic Jake Burton Quotes on Snowboards, Apparel & Accessories

BURLINGTON, Vt., Jan. 9, 2026 /PRNewswire/ -- Burton is proud to unveil 'From Burton to the World', a limited-edition collection of snowboards, apparel and accessories that feature iconic quotes by late Burton founder, Jake Burton Carpenter. Professional snowboarders sponsored by Burton will debut the collection as they compete in Aspen, Colorado and Laax, Switzerland this month, with global availability beginning February 3^rd on Burton.com and at select flagship stores and retail partners worldwide.

"Jake built Burton on a simple belief: snowboarding brings people together," said Donna Carpenter, Burton Owner & Chair of the Board. "While we watch individual athletes compete, what Jake understood and what our riders embody is that snowboarding has always been about community. 'From Burton to the World' celebrates this spirit. Each board carries Jake's words, but more importantly, 'From Burton to the World' represents the passion snowboarders share on and off the mountain. This collection is a tribute to Jake's vision, which is now carried forward by riders around the world who continue to push the sport while staying true to its soul."

Jake's Words, Riders' Choice

Burton Team riders worked directly with designers to select the Jake Burton quotes that resonated most with them. The result: six bold, graphic snowboards in a vibrant color palette, each featuring history-making quotes in block print.

The Collection

'HAVE AS MUCH FUN AS POSSIBLE'

Ridden by: Oliver Martin (USA), Gaon Choi (Korea), Hiroto Ogiwara (Japan), Yiming Su (China), Mitsuki Ono (Japan), Nicola Liviero (Italy), Shaotong Wu (China) and Clemens Millauer (Austria).

'RIDING IS WHERE THE ENERGY COMES FROM & IT'S ALSO WHERE IT GOES'

Ridden by: Anna Gasser (Austria), Ayumu Hirano (Japan), Hanna Karrer (Austria), Reira Iwabuchi (Japan), Romain Allemand (France), Taiga Hasegawa (Japan) and Jakub Hrones (Czech Republic).

'HERE AT BURTON WE TAKE OUR FUN SERIOUSLY'

Ridden by: Brock Crouch (USA), Jiayu Liu (China), Jonas Hasler (Switzerland), Leon Vockensperger (Germany), Øyvind Kirkhus (Norway), Telma Sarkipajou (Finland), Dane Menzies (New Zealand), Zoi Sadowski-Synnott (New Zealand).

'THE BEST THING ABOUT SNOWBOARDING – IT'S NOT HOW YOU LOOK BUT HOW YOU FEEL'

Ridden by: Shuichiro Shigeno (Japan).

'BELIEVE IN SNOWBOARDING'

Ridden by: Kaishu Hirano (Japan).

'QUESTION: IS SNOWBOARDING A FAD? ANSWER: GET SERIOUS'

Ridden by: Cam Melville Ives (New Zealand), Clemens Millauer (Austria), Lu Yang (China), Mark McMorris (Canada) and Mari Fukada (Japan).

Supporting the Riders, Celebrating the Community

Burton is proud to support this incredible global community of riders who carry forward Jake's vision every time they drop in. Fans can celebrate alongside Burton riders and own a piece of snowboarding history with the 'From Burton to the World' collection of snowboards, apparel, and accessories—available in limited quantities worldwide beginning February 3^rd on Burton.com and at select Burton flagship stores and retail partners.

Photo - https://mma.prnasia.com/media2/2857988/Burton_Riders_Debut.jpg?p=medium600

** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **

Burton Riders Debut 'From Burton to the World' Collection in Aspen & Laax