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GI Innovation and GI Biome Advance to the Semi-finals of XPRIZE Healthspan with Anti-Aging Potential of GI-102 and GIB-7 Combination Therapy

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GI Innovation and GI Biome Advance to the Semi-finals of XPRIZE Healthspan with Anti-Aging Potential of GI-102 and GIB-7 Combination Therapy
Business

Business

GI Innovation and GI Biome Advance to the Semi-finals of XPRIZE Healthspan with Anti-Aging Potential of GI-102 and GIB-7 Combination Therapy

2025-05-13 09:21 Last Updated At:11:55

  • GI Innovation and GI Biome have been selected as a Top 40 semi-finalist in the XPRIZE Healthspan competition among 600 registered teams from 58 countries
  • Selected as one of 8 teams to pitch at the XPRIZE Investor Summit in New York
  • The team is now competing for one of the largest prize pools in the history of XPRIZE    
  • SEOUL, South Korea, May 13, 2025 /PRNewswire/ -- GI Innovation, a South Korean biotech company, announced on May 13 that it has been selected as a semi-finalist in the XPRIZE Healthspan competition in collaboration with its sister company GI Biome.

    The XPRIZE Healthspan semi-finals ceremony is taking place in New York from May 12 to 14, with the top 40 semi-finalist teams out of more than 600 registered teams among 58 countries invited. The company has not only advanced to the semi-finals but has also been selected as one of 8 teams among the 40 semi-finalists to earn an exclusive opportunity to present its vision and innovations to high-profile, institutional global investors.

    XPRIZE, a U.S.-based nonprofit foundation, is the recognized global leader in designing and executing large-scale competitions to solve humanity's greatest challenges. For over 30 years, our unique model has democratized crowd-sourced innovation and scientifically scalable solutions that accelerate a more equitable and abundant future. 

    Semi-finalists are selected by an expert committee using rigorous guidelines and advancement into this elite group is seen as recognition of exceptional scientific vision and execution.

    The XPRIZE Healthspan competition, in which the joint GI Innovation - GI Biome team is competing, aims to discover breakthrough treatments that can slow or prevent age-related degeneration. The competition offers a record-breaking total prize pool of approximately USD $101 million.

    Selected as a semi-finalist team, GI Innovation will receive a prize of USD $250,000 to support the next clinical trial stage. Only the top 10 teams from the semi-finals round will advance to the grand finals.

    'Anti-Aging' Strategy with Immune Booster GI-102 and Microbiome-Based GIB-7 Combination

    The GI Innovation-GI Biome joint team proposed a combination therapy consisting of GI-102, an immune-boosting drug, and GIB-7, a microbiome-based synbiotic, as a novel anti-aging approach.

    Clinical studies have shown that GI-102 potently activates CD8+ T cells and NK cells at high doses, allowing those immune cells to safely attack a range of tumor types including melanoma, kidney, lung and bladder cancers. However, at a low dose, it selectively expands and activates NK cells, which are critical for clearing senescent cells and cellular debris, playing a vital role in delaying aging and maintaining physiological functions. Based on this mechanism, GI Innovation is pursuing the use of low-dose GI-102 as an NK cell enhancer.

    GIB-7 is a premium synbiotic developed using GI Biome's proprietary Microbiome+ Herbal Therapy platform. It combines three patented probiotic strains with herbal ingredients. Clinical trials in elderly volunteers at Seoul National University Hospital have already been completed. In an aging mouse model, GIB-7 elicited an increase in beneficial gut microbiota, improved regulation of circadian rhythm, and improved muscle strength.

    "We entered this competition with the goal of winning, and it is a great honor to have passed the first gateway, highlighting the scientific innovation of both GI Innovation and GI Biome," said Dr. Myoung-Ho Jang, CEO and Founder of GI Innovation. "The upcoming clinical trial will be conducted in collaboration with Dr. Katherine Samaras, a key opinion leader in anti-aging research at the Garvan Institute of Medical Research in Australia. Through this competition, we will do our utmost to realize our global vision of progressing from treatment to prevention."


SEOUL, South Korea, May 13, 2025 /PRNewswire/ -- GI Innovation, a South Korean biotech company, announced on May 13 that it has been selected as a semi-finalist in the XPRIZE Healthspan competition in collaboration with its sister company GI Biome.

The XPRIZE Healthspan semi-finals ceremony is taking place in New York from May 12 to 14, with the top 40 semi-finalist teams out of more than 600 registered teams among 58 countries invited. The company has not only advanced to the semi-finals but has also been selected as one of 8 teams among the 40 semi-finalists to earn an exclusive opportunity to present its vision and innovations to high-profile, institutional global investors.

XPRIZE, a U.S.-based nonprofit foundation, is the recognized global leader in designing and executing large-scale competitions to solve humanity's greatest challenges. For over 30 years, our unique model has democratized crowd-sourced innovation and scientifically scalable solutions that accelerate a more equitable and abundant future. 

Semi-finalists are selected by an expert committee using rigorous guidelines and advancement into this elite group is seen as recognition of exceptional scientific vision and execution.

The XPRIZE Healthspan competition, in which the joint GI Innovation - GI Biome team is competing, aims to discover breakthrough treatments that can slow or prevent age-related degeneration. The competition offers a record-breaking total prize pool of approximately USD $101 million.

Selected as a semi-finalist team, GI Innovation will receive a prize of USD $250,000 to support the next clinical trial stage. Only the top 10 teams from the semi-finals round will advance to the grand finals.

'Anti-Aging' Strategy with Immune Booster GI-102 and Microbiome-Based GIB-7 Combination

The GI Innovation-GI Biome joint team proposed a combination therapy consisting of GI-102, an immune-boosting drug, and GIB-7, a microbiome-based synbiotic, as a novel anti-aging approach.

Clinical studies have shown that GI-102 potently activates CD8+ T cells and NK cells at high doses, allowing those immune cells to safely attack a range of tumor types including melanoma, kidney, lung and bladder cancers. However, at a low dose, it selectively expands and activates NK cells, which are critical for clearing senescent cells and cellular debris, playing a vital role in delaying aging and maintaining physiological functions. Based on this mechanism, GI Innovation is pursuing the use of low-dose GI-102 as an NK cell enhancer.

GIB-7 is a premium synbiotic developed using GI Biome's proprietary Microbiome+ Herbal Therapy platform. It combines three patented probiotic strains with herbal ingredients. Clinical trials in elderly volunteers at Seoul National University Hospital have already been completed. In an aging mouse model, GIB-7 elicited an increase in beneficial gut microbiota, improved regulation of circadian rhythm, and improved muscle strength.

"We entered this competition with the goal of winning, and it is a great honor to have passed the first gateway, highlighting the scientific innovation of both GI Innovation and GI Biome," said Dr. Myoung-Ho Jang, CEO and Founder of GI Innovation. "The upcoming clinical trial will be conducted in collaboration with Dr. Katherine Samaras, a key opinion leader in anti-aging research at the Garvan Institute of Medical Research in Australia. Through this competition, we will do our utmost to realize our global vision of progressing from treatment to prevention."

** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **

GI Innovation and GI Biome Advance to the Semi-finals of XPRIZE Healthspan with Anti-Aging Potential of GI-102 and GIB-7 Combination Therapy

GI Innovation and GI Biome Advance to the Semi-finals of XPRIZE Healthspan with Anti-Aging Potential of GI-102 and GIB-7 Combination Therapy

  • Executive Chair Chung emphasizes customer-focused transformation and ecosystem strengthening to navigate evolving market dynamics and lead new industry standards
  • Presents strategic priorities, including agile decision-making, ecosystem competitiveness, and bold collaboration with diverse partners
  • Executives discuss AI internalization, digital transformation strategies, and business growth initiatives during candid roundtable with global employees

SEOUL, South Korea, Jan. 5, 2026 /PRNewswire/ -- Hyundai Motor Group (The Group) today shared its 2026 strategic vision with global employees, with Executive Chair Euisun Chung presenting priorities focused on continuous customer-focused transformation, strengthened ecosystem competitiveness, and AI-driven innovation to navigate evolving market dynamics and lead new industry standards.

During his new year remarks, Executive Chair Chung presented five key strategic priorities — customer-focused evolution, agile decision-making, ecosystem competitiveness, bold collaboration, and leading new industry standards — to navigate the evolving global landscape.

Driving Transformation Through Customer Focus

Executive Chair Chung opened by expressing gratitude to employees and customers, acknowledging 2025's unprecedented business environment changes while thanking employees for their exceptional performance and customers for their continued trust. He noted that 2026 will bring both headwinds and opportunities as the global business landscape continues to evolve rapidly.

Chung emphasized continuous transformation driven by customer insights. "When conditions get tough and competition fierce, our greatest strength will be our ability to continuously evolve by staying close to our customers," he said.

Specifically, he encouraged employees to take a moment and assess some fundamental questions: "Did we thoroughly reflect customers' perspectives in our products? Did we ever compromise in the process of planning or development? Can we confidently speak of our quality in front of customers? Through these questions, we can look back upon ourselves squarely and strive for progress, thereby keeping ourselves resilient against any challenges," he said.

Agile Decision-Making Through Direct Engagement

Executive Chair Chung welcomed transformation in work methods and leadership. "Leaders must step out into the field, engage directly with people, and understand the essence of situations firsthand," he said.

He emphasized the importance of speed and clarity in organizational operations. "Above all, what matters most is fast and clear communication, and agile decision-making that is free from formality. Let us work more efficiently," he said, highlighting that by fresh thinking of its approaches, the Group can continue to achieve innovation.

Building Competitive Advantage Through Ecosystem Strength

Executive Chair Chung reinforced the importance of ecosystem strength, noting that Group businesses such as vehicle and humanoid robot manufacturing each involve tens of thousands of components, requiring exceptional performance and quality across the entire production chain.

"The strength of our supply ecosystem directly amplifies our competitive advantage. Sustainable growth is possible only when the whole ecosystem stays healthy," he said.

Bold Collaboration for AI-Driven Transformation

Executive Chair Chung emphasized that as AI technology rapidly develops and competitive dynamics shift, the global manufacturing industry is undergoing a major transition. He highlighted the need to advance through bold collaboration with diverse partners in navigating this AI-driven transformation.

"Looking at the automotive market alone, we've entered an era where core product competitiveness is determined by AI capabilities," he noted. Chung emphasized that Hyundai Motor Group is rapidly building capabilities to compete at the highest level, leveraging world-class product design and manufacturing expertise, plus valuable data from manufacturing sites and user experiences.

He shared his strong belief in the Group's competitiveness in the physical AI field and how this will continue to grow to serve customers. "We possess world-class capabilities in the design and manufacturing of physical products. If we envision a bigger future and boldly expand collaboration with various partners to broaden the industrial ecosystem, I am confident we will deliver greater value to customers," he said.

More information about Hyundai Motor Group can be found at: http://www.hyundaimotorgroup.com or Newsroom: Media Hub by HyundaiKia Global Media Center (kianewscenter.com)Genesis Newsroom 

  • Executive Chair Chung emphasizes customer-focused transformation and ecosystem strengthening to navigate evolving market dynamics and lead new industry standards
  • Presents strategic priorities, including agile decision-making, ecosystem competitiveness, and bold collaboration with diverse partners
  • Executives discuss AI internalization, digital transformation strategies, and business growth initiatives during candid roundtable with global employees

SEOUL, South Korea, Jan. 5, 2026 /PRNewswire/ -- Hyundai Motor Group (The Group) today shared its 2026 strategic vision with global employees, with Executive Chair Euisun Chung presenting priorities focused on continuous customer-focused transformation, strengthened ecosystem competitiveness, and AI-driven innovation to navigate evolving market dynamics and lead new industry standards.

During his new year remarks, Executive Chair Chung presented five key strategic priorities — customer-focused evolution, agile decision-making, ecosystem competitiveness, bold collaboration, and leading new industry standards — to navigate the evolving global landscape.

Driving Transformation Through Customer Focus

Executive Chair Chung opened by expressing gratitude to employees and customers, acknowledging 2025's unprecedented business environment changes while thanking employees for their exceptional performance and customers for their continued trust. He noted that 2026 will bring both headwinds and opportunities as the global business landscape continues to evolve rapidly.

Chung emphasized continuous transformation driven by customer insights. "When conditions get tough and competition fierce, our greatest strength will be our ability to continuously evolve by staying close to our customers," he said.

Specifically, he encouraged employees to take a moment and assess some fundamental questions: "Did we thoroughly reflect customers' perspectives in our products? Did we ever compromise in the process of planning or development? Can we confidently speak of our quality in front of customers? Through these questions, we can look back upon ourselves squarely and strive for progress, thereby keeping ourselves resilient against any challenges," he said.

Agile Decision-Making Through Direct Engagement

Executive Chair Chung welcomed transformation in work methods and leadership. "Leaders must step out into the field, engage directly with people, and understand the essence of situations firsthand," he said.

He emphasized the importance of speed and clarity in organizational operations. "Above all, what matters most is fast and clear communication, and agile decision-making that is free from formality. Let us work more efficiently," he said, highlighting that by fresh thinking of its approaches, the Group can continue to achieve innovation.

Building Competitive Advantage Through Ecosystem Strength

Executive Chair Chung reinforced the importance of ecosystem strength, noting that Group businesses such as vehicle and humanoid robot manufacturing each involve tens of thousands of components, requiring exceptional performance and quality across the entire production chain.

"The strength of our supply ecosystem directly amplifies our competitive advantage. Sustainable growth is possible only when the whole ecosystem stays healthy," he said.

Bold Collaboration for AI-Driven Transformation

Executive Chair Chung emphasized that as AI technology rapidly develops and competitive dynamics shift, the global manufacturing industry is undergoing a major transition. He highlighted the need to advance through bold collaboration with diverse partners in navigating this AI-driven transformation.

"Looking at the automotive market alone, we've entered an era where core product competitiveness is determined by AI capabilities," he noted. Chung emphasized that Hyundai Motor Group is rapidly building capabilities to compete at the highest level, leveraging world-class product design and manufacturing expertise, plus valuable data from manufacturing sites and user experiences.

He shared his strong belief in the Group's competitiveness in the physical AI field and how this will continue to grow to serve customers. "We possess world-class capabilities in the design and manufacturing of physical products. If we envision a bigger future and boldly expand collaboration with various partners to broaden the industrial ecosystem, I am confident we will deliver greater value to customers," he said.

More information about Hyundai Motor Group can be found at: http://www.hyundaimotorgroup.com or Newsroom: Media Hub by HyundaiKia Global Media Center (kianewscenter.com)Genesis Newsroom 

** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **

Hyundai Motor Group Executive Chair Chung Presents 2026 Vision: Customer-Focused Transformation and AI-Driven Ecosystem Collaboration

Hyundai Motor Group Executive Chair Chung Presents 2026 Vision: Customer-Focused Transformation and AI-Driven Ecosystem Collaboration

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