Waters Integrates Multi-Angle Light Scattering Detectors with Empower Software for Improved Biologics Quality Control and Simplified Regulatory Compliance

News Summary 

MILFORD, Mass., May 13, 2025 /PRNewswire/ -- Waters Corporation (NYSE:WAT) today announced that its Empower™ Software now supports biologics data acquisition and quality control (QC) analysis from Multi-Angle Light Scattering (MALS) and differential Refractive Index (RI) instruments in its Wyatt Technology™ Portfolio. This integration expands the scope of critical quality attributes that a biopharmaceutical laboratory can manage using Empower Software. Additionally, this advancement will simplify the process and digital footprint of acquiring and submitting compliant data to regulatory authorities – from biologics development through QC – saving customers up to six months of software validation time.

Empower Software is the industry's most established and compliant-ready chromatography data system (CDS), widely adopted globally and used to submit data for more than 80% of novel drugs to regulatory authorities.⁴ The new integration unlocks the ability to use MALS techniques in quality control for biotherapeutics, improving efficiency and Good Manufacturing Practices (GMP) readiness, while reducing end-user training in compliant settings.

"Today's launch of Empower for Multi-Angle Light Scattering Detectors underscores our commitment from the Wyatt acquisition to integrate advanced analytical technologies into our Empower CDS ecosystem," said Dr. Udit Batra, President & CEO, Waters Corporation. "Specifically, MALS supported on Empower Software reveals high molecular weight species that are not visible to other detectors – reducing the risk of erroneous results in biotherapeutic quality control. By combining the strengths of compliant software with deep analytical light scattering instrumentation, we are providing customers with a unified solution that enhances productivity and data accuracy – ultimately supporting high-volume QC testing to ensure the safety of life-saving biologic therapies for patients."

The integration of the DAWNâ„¢, miniDAWNâ„¢, and OptiLabâ„¢ Detectors will enable the measurement of more critical quality attributes of peptides and proteins in a single run, reducing analysis time by 20% and providing earlier insights into the stability, safety, and efficacy of biologics.

"As a Contract Development and Manufacturing Organization (CDMO), we anticipate that MALS on Empower Software will enhance our service offerings," said William Wittbold, Senior Director of Operations, at Pace Analytical. "The detailed MALS data is essential for understanding complex biotherapeutics. Combined with the reliability of Empower Software, we believe this integration will deliver exceptional value to our customers, ensuring our drug development partners receive the highest quality results."

The capability to integrate the DAWN, miniDAWN, and OptiLab Detectors with Empower Software will be available for peptide and protein workflows in July 2025. Learn more by visiting our product page. 

Additional Resources

     -       Learn more about the MALS integration with Empower Software.
     -       Follow and connect with Waters LinkedIn, Twitter, and Facebook.

ABOUT: Waters Corporation (NYSE:WAT) is a global leader in analytical instruments, separations technologies, and software, serving the life, materials, food, and environmental sciences for over 65 years. Our Company helps ensure the efficacy of medicines, the safety of food and the purity of water, and the quality and sustainability of products used every day. In over 100 countries, our 7,600+ passionate employees collaborate with customers in laboratories, manufacturing sites, and hospitals to accelerate the benefits of pioneering science.

Waters, Empower, DAWN, miniDAWN, OptiLab, and Wyatt Technology are trademarks of Waters Technologies Corporation.

Contact:

Molly Gluck
Head of External Communications
Waters Corporation
molly_gluck@waters.com
Mobile: +1.617.833.8166

1. In a recent survey of 50 MALS users, responding to the question "How long does it typically take you to validate new software in a GxP lab," the average time was reported as 6 months since it is one software instead of two.

2. In a recent survey of 50 MALS users, responding to the question "How much time, as a percentage of total working time, would you save on average if you could use your primary CDS software (LC software) for MALS data analysis," the average time saving was reported as 20%.

3. White paper WP1615: "SEC-MALS for absolute biophysical characterization" describes the challenges associated with determining basic physical properties of biologics in solution, and provides examples of how multi-angle light scattering can reduce the occurrence of erroneous results prevalent in relative measurement techniques. MALS provides absolute results from first principles, avoiding errors of relative measures, and is independent of retention time, reference materials, and column interactions.

4. Presented at the J.P. Morgan 43rd Annual Healthcare Conference. According to internal analysis, ~80% of the drugs filed with the FDA, EMA, and China National Medical Products Administration (NMPA) in 2023 were done so using Empower Software. Source: Waters data and estimates.

** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **

Waters Integrates Multi-Angle Light Scattering Detectors with Empower Software for Improved Biologics Quality Control and Simplified Regulatory Compliance

BANGKOK, June 13, 2025 /PRNewswire/ -- Ultimate Game Co., Ltd., a premier Thai-based online game publisher, has unveiled a bold strategic investment exceeding 100 million Baht to solidify its footprint in Southeast Asia's rapidly expanding mobile gaming sector. The initiative underscores the company's commitment to delivering high-quality MMORPG content and driving sustainable regional growth.

Mr. Attachet Chaichanasongkram, CEO and Co-Founder of Ultimate Game, shared the company's vision for 2025: "At Ultimate Game, we are dedicated to offering premium MMORPG mobile games that align with the preferences of Southeast Asian gamers—over 82% of whom prefer mobile gaming, with 65% favoring the MMORPG genre. With more than 15 years of industry experience and the support of global partners like Google, we are confident in our ability to deliver engaging, data-driven content tailored to the region's evolving demands."

The company continues to build on the success of its hit title LUNA ORIGIN, while preparing for the launch of several new titles in 2025. The sizable investment will be directed toward marketing and operations across Southeast Asia, with a target of attracting over 1.25 million players during the launch window.

To support this expansion, Ultimate Game has significantly scaled its multilingual Customer Service operations—including Thai, English, and Bahasa Indonesia—by integrating advanced support technologies and prioritizing exceptional player experience.

"Our long-term ambition is to become a publicly listed company within five years," Mr. Attachet added. "We aim to be a top-tier mobile game provider across Southeast Asia, with at least two major game launches planned for next year alone."

Mr. Kodchawara Vanichayapron, Chief Marketing Officer and Co-Founder, outlined the company's go-to-market strategy: "Our 2025 marketing roadmap focuses on penetrating the Southeast Asian market by engaging three core gamer segments: Hardcore MMORPG enthusiasts, casual mobile users, and esports-driven competitive players. We are aligning game content and community strategies with localized trends and mobile-first behaviors in Thailand and beyond."

The mobile gaming industry in Southeast Asia is projected to grow at an average annual rate of 7.41% between 2025 and 2033, with Thailand expected to see consistent growth of 7–10% per year. Therefore, Ultimate Game is implementing a comprehensive Localization strategy—customizing content and user experiences to meet the specific needs of each market. This is supported by a data-driven Digital Marketing approach, utilizing advanced analytics tools in collaboration with global partners such as Google and Soul M Game to precisely target key demographics. The company prioritizes games with strong IPs, stable infrastructures, and high potential for long-term community engagement, while also leveraging technologies like the Unity Engine, AI, and Big Data to optimize both development and marketing performance.

In 2025, Ultimate Game aims to increase downloads and active user numbers by 20–30%, focusing on brand awareness, community engagement, experiential campaigns, and especially the new MORPGs.

Stay informed at: www.ultimategame.net

** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **

ULTIMATE GAME COMMITS OVER 100 MILLION BAHT TO ADVANCE THAI GAMING INDUSTRY AND EXPAND ACROSS SOUTHEAST ASIA