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Porton Advanced Announces Collaboration with TongEYE to Accelerate Development of iPSC-RPEC transplantation therapy

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Porton Advanced Announces Collaboration with TongEYE to Accelerate Development of iPSC-RPEC transplantation therapy
Business

Business

Porton Advanced Announces Collaboration with TongEYE to Accelerate Development of iPSC-RPEC transplantation therapy

2025-05-22 21:00 Last Updated At:21:15

SUZHOU, China, May 22, 2025 /PRNewswire/ -- Porton Advanced, a leading contract development and manufacturing organization (CDMO) specializing in advanced therapy medicinal products (ATMPs), is pleased to announce its partnership with TongEye Medical Technology (TongEYE), an innovator focusing on cell therapy drugs for ophthalmic diseases. Porton Advanced will provide comprehensive CDMO services to support iPSC-derived retinal pigment epithelium cell (RPEC) therapy program, including CMC development and IND application assistance, to accelerate the therapy development progress.

The iPSC-RPEC transplantation therapy has demonstrated significant potential in addressing blinding eye diseases such as age-related macular degeneration (AMD). TongEYE has established highly efficient and proprietary induction method for differentiation through pioneering work in retinal disease mechanisms and innovative therapies. This collaboration leverages Porton Advanced's extensive expertise in iPSC and cell therapy to provide end-to-end CDMO services encompassing iPSC reprogramming and cell banking, process optimization for RPE-directed differentiation, GMP manufacturing of RPE cells, rigorous quality studies, and IND application support.

"We are pleased to partner with Porton Advanced, a leading CDMO with proven track records," said Dr. Guo-Tong Xu, Founder and Chief Scientist of TongEYE. "Their CDMO capabilities and project experience in iPSC will significantly accelerate our ophthalmic cell therapy development program to benefit patients sooner."

Andrew Chen, CFO of Porton Advanced, commented: "TongEYE's R&D team has developed a robust RPE differentiation method and the products have been showing safety and functionality in preclinical studies. Through this collaboration, we will combine our iPSC-CMC expertise with their innovative platform to overcome key technical challenges in iPSC-based therapy development. Porton Advanced will integrate the international R&D expertise and rigorous quality systems and provide comprehensive support to advance this promising treatment globally."

About TongEYE

TongEye Medical Technology (Ningbo) Co., Ltd. was established in October 2023, focusing mainly on the development and production of cell therapy drugs for ophthalmic diseases. In November, the company completed its angel round of financing. The company has multiple research and development pipelines. Among them, the key project of transplanting unique naive RPE cells derived from iPSCs for the treatment of dry retinal degeneration has achieved significantly better therapeutic effects in animal models compared with matureRPE cells. The established highly efficient induction and differentiation method with independent intellectual property rights has shortened the traditional differentiation cycle from 120 to 150 days to just 25 days, significantly reducing costs and improving accessibility. This brings hope for vision improvement to hundreds of millions of patients with dry retinal degeneration worldwide.

About Porton Advanced

Porton Advanced Solutions is a subsidiary of the leading CDMO, Porton Pharma Solutions. Porton Advanced has headquarters in Cranbury, New Jersey, and two GMP sites in Suzhou, China, providing end-to-end CDMO solutions for ATMPs. We offer services from cell banking, process, and analytical method development, cGMP production to fill & finish, covering different stages of drug development from early research, IITs, Investigational New Drug (IND) applications, clinical trials, New Drug Applications (NDA), to commercialization.

Porton Advanced has developed specialized CRO and CDMO platforms focusing on plasmids, viral vectors (lentiviral vector, adenoviral vector, AAV,etc), cell therapy CMC services including CAR-T, TCR-T, CAR-NK, HSC, exosome, etc) and nucleic acid therapies. Our state-of-the-art, GMP-compliant facilities span an impressive 215,000 sqft, equipped with 10 viral vector production lines, 12 GMP-compliant cell therapy production suites (including 2 suites for infectious donors), and a multitude of clean rooms. As of now, we have successfully supported our clients to secure 18 global IND approvals from NMPA, FDA, and Medsafe, with 5 ongoing Phase I/II ATMP projects. Additionally, Porton Advanced has supported the successful transition of several overseas clinical-stage pipelines into China.

** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **

Porton Advanced Announces Collaboration with TongEYE to Accelerate Development of iPSC-RPEC transplantation therapy

Porton Advanced Announces Collaboration with TongEYE to Accelerate Development of iPSC-RPEC transplantation therapy

  • Innovative technologies enable retailers to implement intelligent stores at scale to deliver smarter, more responsive shopping experiences
  • Industry partners to display production-ready AI solutions for loss prevention, digital twins, AI agents, customer analytics, and more

SAN JOSE, Calif. and NEW YORK, Jan. 11, 2026 /PRNewswire/ -- Retail's Big Show -- Super Micro Computer, Inc. (SMCI), a Total IT Solution Provider for AI/ML, HPC, Cloud, Storage, and 5G/Edge, today announced collaboration with technology partners for AI-powered intelligent in-store retail solutions designed to meet increasing customer expectations with scalability, improved productivity and increased profitability.

"AI is reshaping shopping experiences, enabling real-time analysis of video and other data to give retailers actionable insights to optimizing staff efficiency, reducing shrinkage, increasing profits, and avoiding stock-outs," said Charles Liang, president and CEO of Supermicro. "By combining Supermicro's complete and scalable AI platforms with NVIDIA RTX PRO accelerated computing solutions, we're enabling retailers to build intelligent stores that maximize the benefits of AI-driven applications."

According to the latest NVIDIA State of AI in Retail & CPG report, 89% of respondents reported that AI is helping to increase annual revenue, while 95% said it is helping decrease annual costs, highlighting the measurable business impact retailers are already achieving because of AI1.

For more information, please visit https://www.supermicro.com/en/products/edge/servers

Supermicro Complete and Scalable Edge AI Infrastructure

Retail-centric AI applications require sub-second responsiveness which is only possible, at scale, if data is processed directly at the edge. Supermicro's Edge AI infrastructure enables the deployment of solutions in distributed environments, such as intelligent retail stores and supply chains, to provide a complete solution.

Deploying at the edge presents a myriad of unique challenges in comparison to the data center. Supermicro's broad Edge AI portfolio of products helps customers and partners overcome these challenges while striking the right balance between performance and ROI.

For deployments in harsh environments where conditioned space is not available, the fanless E103 series of products bring AI processing power where it couldn't go before. Supermicro also offers a fanned small form factor E300 series systems with AI capabilities.

When there is a demanding AI workload at the edge, customers and partners can turn to numerous systems capable of holding the latest discrete GPUs for AI acceleration. Ranging from 1U short-depth to larger 4U form factors, solutions can be right-sized to meet the customer's needs by enabling the latest generation of NVIDIA RTX PRO Blackwell series.

Supermicro Intelligent Store Partners

Supermicro is collaborating with ecosystem partners including Everseen, Kinetic Vision, ALLSIDES, LiveX, WobotAI, and Aible, to create intelligent stores that positively impact day-to-day retail operations as well as longer term supply chain management.

  • Everseen's Evercheck solution uses Vision AI to help reduce shrink and improve staff productivity and customer experiences. Built on the Everseen Vision AI platform, Evercheck detects, and deters recovery of unwanted behaviors at checkout, helping retailers recover losses and streamline front-of-store operations.

"Everseen has spent years working alongside some of the world's largest retailers, understanding the realities of the store floor and solving loss challenges where they actually happen," said Joe White, CEO of Everseen. "By partnering with Supermicro and leveraging NVIDIA-accelerated computing, Evercheck delivers real-time computer vision at the edge - transforming store activity into intelligence retailers can act on immediately."

  • Wobot AI, focused on building Video AI Agents for the physical world, will be demonstrating how the cameras retailers already own can be turned into systems that continuously observe, learn, and produce usable insight. By converting ordinary CCTV infrastructure into autonomous agents that recognize patterns, identify friction, and surface decisions, Wobot's AI Agents enable retailers to improve day-to-day operations with practical and measurable outcomes.

"By working with Supermicro and NVIDIA at the edge, we're able to deploy Video AI Agents in a way that's scalable, reliable, and focused on real-time operational insight—not experimentation," said Will Kelso, President, Revenue & Growth at Wobot AI.

  • LiveX AI - "Retail is entering an era where AI agents become the default interaction layer between brands and customers," said Jerry Li, Co-Founder and CEO of LiveX AI. "With NVIDIA's accelerated AI and Supermicro's edge infrastructure, we can deploy a helpful, human-like AI agent directly in physical spaces—such as kiosks or holograms—bringing the speed, intelligence, and continuity of digital experiences into brick-and-mortar environments. This collaboration makes AI agents usable, in real time, where customers actually are."

    • Kinetic Vision and ALLSIDES are bundling their expertise for a True Digital Twin solution designed to develop, test, and optimize supply chain processes, checkout stations, and other complex systems.

"The combination of Supermicro's high reliability optimized infrastructure and NVIDIA's accelerated computing stack gives Kinetic Vision the foundation to innovate at speed. Together, we are helping retailers move from experimentation to production-ready AI solutions that drive measurable operational and customer experience gains," says Jeremy Jarratt, Kinetic Vision CEO.

Franz Tschimben, CEO at ALLSIDES, adds: "Building on the combined strengths of NVIDIA and Supermicro, we deliver a high-fidelity 3D digital twin data layer for AI training that enables retailers to power applications across the entire retail value chain — from training robots with physical AI, to production and production planning, virtual store layouts and consumer feedback systems, and e-commerce integrations — helping drive higher conversion rates, faster decision-making, and greater operational efficiency."

  • Supermicro will also feature Superb AI's retail-focused VSS solution, combining Superb AI's proprietary VLM with NVIDIA AI Blueprint components to enable subjective reasoning capabilities, natural-language search, automated incident summarization, and customer behavior insights across store camera networks.
  • Aible will highlight its automated agent solution, which analyzes vast amounts of data across millions of patterns to explain changes in retail KPIs, such as the average purchase amount or number of purchases. Aible will also demonstrate how the latest NVIDIA Retail blueprints can be incorporated into agentic solutions that automatically customize customer experiences and optimize retail operations at scale.

Arijit Sengupta, CEO of Aible, adds, "Today's market and labor conditions are constantly changing. Only autonomous agents can understand and adjust to these ever-changing patterns of customer behavior, inventory costs and supply, and labor access at scale. Working with NVIDIA and Supermicro, Aible brings autonomous agents subject to business user review to the retail edge."

These intelligent retail solutions will be demonstrated by Supermicro and its partners at NRF: Retail's Big Show in New York City from January 11-13. To learn more about AI-powered retail applications or Supermicro's AI Infrastructure solutions, visit Supermicro booth #5281 and attend its speaking session featuring PepsiCo and Kinetic Vision. For more details, please visit www.supermicro.com/NRF

1Source: "NVIDIA State of AI in Retail and CPG" 2026

About Super Micro Computer, Inc.

Supermicro (NASDAQ: SMCI) is a global leader in Application-Optimized Total IT Solutions. Founded and operating in San Jose, California, Supermicro is committed to delivering first to market innovation for Enterprise, Cloud, AI, and 5G Telco/Edge IT Infrastructure. We are a Total IT Solutions provider with server, AI, storage, IoT, switch systems, software, and support services. Supermicro's motherboard, power, and chassis design expertise further enables our development and production, enabling next generation innovation from cloud to edge for our global customers. Our products are designed and manufactured in-house (in the US, Asia, and the Netherlands), leveraging global operations for scale and efficiency and optimized to improve TCO and reduce environmental impact (Green Computing). The award-winning portfolio of Server Building Block Solutions® allows customers to optimize for their exact workload and application by selecting from a broad family of systems built from our flexible and reusable building blocks that support a comprehensive set of form factors, processors, memory, GPUs, storage, networking, power, and cooling solutions (air-conditioned, free air cooling or liquid cooling).

Supermicro, Server Building Block Solutions, and We Keep IT Green are trademarks and/or registered trademarks of Super Micro Computer, Inc.

All other brands, names, and trademarks are the property of their respective owners.

 

  • Innovative technologies enable retailers to implement intelligent stores at scale to deliver smarter, more responsive shopping experiences
  • Industry partners to display production-ready AI solutions for loss prevention, digital twins, AI agents, customer analytics, and more

SAN JOSE, Calif. and NEW YORK, Jan. 11, 2026 /PRNewswire/ -- Retail's Big Show -- Super Micro Computer, Inc. (SMCI), a Total IT Solution Provider for AI/ML, HPC, Cloud, Storage, and 5G/Edge, today announced collaboration with technology partners for AI-powered intelligent in-store retail solutions designed to meet increasing customer expectations with scalability, improved productivity and increased profitability.

"AI is reshaping shopping experiences, enabling real-time analysis of video and other data to give retailers actionable insights to optimizing staff efficiency, reducing shrinkage, increasing profits, and avoiding stock-outs," said Charles Liang, president and CEO of Supermicro. "By combining Supermicro's complete and scalable AI platforms with NVIDIA RTX PRO accelerated computing solutions, we're enabling retailers to build intelligent stores that maximize the benefits of AI-driven applications."

According to the latest NVIDIA State of AI in Retail & CPG report, 89% of respondents reported that AI is helping to increase annual revenue, while 95% said it is helping decrease annual costs, highlighting the measurable business impact retailers are already achieving because of AI1.

For more information, please visit https://www.supermicro.com/en/products/edge/servers

Supermicro Complete and Scalable Edge AI Infrastructure

Retail-centric AI applications require sub-second responsiveness which is only possible, at scale, if data is processed directly at the edge. Supermicro's Edge AI infrastructure enables the deployment of solutions in distributed environments, such as intelligent retail stores and supply chains, to provide a complete solution.

Deploying at the edge presents a myriad of unique challenges in comparison to the data center. Supermicro's broad Edge AI portfolio of products helps customers and partners overcome these challenges while striking the right balance between performance and ROI.

For deployments in harsh environments where conditioned space is not available, the fanless E103 series of products bring AI processing power where it couldn't go before. Supermicro also offers a fanned small form factor E300 series systems with AI capabilities.

When there is a demanding AI workload at the edge, customers and partners can turn to numerous systems capable of holding the latest discrete GPUs for AI acceleration. Ranging from 1U short-depth to larger 4U form factors, solutions can be right-sized to meet the customer's needs by enabling the latest generation of NVIDIA RTX PRO Blackwell series.

Supermicro Intelligent Store Partners

Supermicro is collaborating with ecosystem partners including Everseen, Kinetic Vision, ALLSIDES, LiveX, WobotAI, and Aible, to create intelligent stores that positively impact day-to-day retail operations as well as longer term supply chain management.

  • Everseen's Evercheck solution uses Vision AI to help reduce shrink and improve staff productivity and customer experiences. Built on the Everseen Vision AI platform, Evercheck detects, and deters recovery of unwanted behaviors at checkout, helping retailers recover losses and streamline front-of-store operations.

"Everseen has spent years working alongside some of the world's largest retailers, understanding the realities of the store floor and solving loss challenges where they actually happen," said Joe White, CEO of Everseen. "By partnering with Supermicro and leveraging NVIDIA-accelerated computing, Evercheck delivers real-time computer vision at the edge - transforming store activity into intelligence retailers can act on immediately."

  • Wobot AI, focused on building Video AI Agents for the physical world, will be demonstrating how the cameras retailers already own can be turned into systems that continuously observe, learn, and produce usable insight. By converting ordinary CCTV infrastructure into autonomous agents that recognize patterns, identify friction, and surface decisions, Wobot's AI Agents enable retailers to improve day-to-day operations with practical and measurable outcomes.

"By working with Supermicro and NVIDIA at the edge, we're able to deploy Video AI Agents in a way that's scalable, reliable, and focused on real-time operational insight—not experimentation," said Will Kelso, President, Revenue & Growth at Wobot AI.

  • LiveX AI - "Retail is entering an era where AI agents become the default interaction layer between brands and customers," said Jerry Li, Co-Founder and CEO of LiveX AI. "With NVIDIA's accelerated AI and Supermicro's edge infrastructure, we can deploy a helpful, human-like AI agent directly in physical spaces—such as kiosks or holograms—bringing the speed, intelligence, and continuity of digital experiences into brick-and-mortar environments. This collaboration makes AI agents usable, in real time, where customers actually are."

    • Kinetic Vision and ALLSIDES are bundling their expertise for a True Digital Twin solution designed to develop, test, and optimize supply chain processes, checkout stations, and other complex systems.

"The combination of Supermicro's high reliability optimized infrastructure and NVIDIA's accelerated computing stack gives Kinetic Vision the foundation to innovate at speed. Together, we are helping retailers move from experimentation to production-ready AI solutions that drive measurable operational and customer experience gains," says Jeremy Jarratt, Kinetic Vision CEO.

Franz Tschimben, CEO at ALLSIDES, adds: "Building on the combined strengths of NVIDIA and Supermicro, we deliver a high-fidelity 3D digital twin data layer for AI training that enables retailers to power applications across the entire retail value chain — from training robots with physical AI, to production and production planning, virtual store layouts and consumer feedback systems, and e-commerce integrations — helping drive higher conversion rates, faster decision-making, and greater operational efficiency."

  • Supermicro will also feature Superb AI's retail-focused VSS solution, combining Superb AI's proprietary VLM with NVIDIA AI Blueprint components to enable subjective reasoning capabilities, natural-language search, automated incident summarization, and customer behavior insights across store camera networks.
  • Aible will highlight its automated agent solution, which analyzes vast amounts of data across millions of patterns to explain changes in retail KPIs, such as the average purchase amount or number of purchases. Aible will also demonstrate how the latest NVIDIA Retail blueprints can be incorporated into agentic solutions that automatically customize customer experiences and optimize retail operations at scale.

Arijit Sengupta, CEO of Aible, adds, "Today's market and labor conditions are constantly changing. Only autonomous agents can understand and adjust to these ever-changing patterns of customer behavior, inventory costs and supply, and labor access at scale. Working with NVIDIA and Supermicro, Aible brings autonomous agents subject to business user review to the retail edge."

These intelligent retail solutions will be demonstrated by Supermicro and its partners at NRF: Retail's Big Show in New York City from January 11-13. To learn more about AI-powered retail applications or Supermicro's AI Infrastructure solutions, visit Supermicro booth #5281 and attend its speaking session featuring PepsiCo and Kinetic Vision. For more details, please visit www.supermicro.com/NRF

1Source: "NVIDIA State of AI in Retail and CPG" 2026

About Super Micro Computer, Inc.

Supermicro (NASDAQ: SMCI) is a global leader in Application-Optimized Total IT Solutions. Founded and operating in San Jose, California, Supermicro is committed to delivering first to market innovation for Enterprise, Cloud, AI, and 5G Telco/Edge IT Infrastructure. We are a Total IT Solutions provider with server, AI, storage, IoT, switch systems, software, and support services. Supermicro's motherboard, power, and chassis design expertise further enables our development and production, enabling next generation innovation from cloud to edge for our global customers. Our products are designed and manufactured in-house (in the US, Asia, and the Netherlands), leveraging global operations for scale and efficiency and optimized to improve TCO and reduce environmental impact (Green Computing). The award-winning portfolio of Server Building Block Solutions® allows customers to optimize for their exact workload and application by selecting from a broad family of systems built from our flexible and reusable building blocks that support a comprehensive set of form factors, processors, memory, GPUs, storage, networking, power, and cooling solutions (air-conditioned, free air cooling or liquid cooling).

Supermicro, Server Building Block Solutions, and We Keep IT Green are trademarks and/or registered trademarks of Super Micro Computer, Inc.

All other brands, names, and trademarks are the property of their respective owners.

 

** The press release content is from PR Newswire. Bastille Post is not involved in its creation. **

Supermicro Announces Intelligent In-Store Retail Solutions in Collaboration with a Broad Range of Industry Partners

Supermicro Announces Intelligent In-Store Retail Solutions in Collaboration with a Broad Range of Industry Partners

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