The images of cars set ablaze, protesters tossing rocks at police and officers firing nonlethal rounds and tear gas at protesters hearkens back to the last time a president sent the National Guard to respond to violence on Los Angeles streets.
But the unrest during several days of protests over immigration enforcement is far different in scale from the 1992 riots that followed the acquittal of white police officers who were videotaped beating Black motorist Rodney King.
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FILE - In this April 29, 1992 file photo, demonstrators protest the verdict in the Rodney King beating case in front of the Los Angeles Police Department headquarters in Los Angeles. (AP Photo/Nick Ut, File)
FILE - A California Highway Patrol officer stands guard at Ninth Street and Vermont Avenue in Los Angeles as smoke rises from a fire further down the street, April 30, 1992. (AP Photo/David Longstreath, file)
FILE - In this April 30, 1992 file photo, smoke rises from a shopping center burned by rioters in Los Angeles after four police officers had been acquitted of the 1991 beating of motorist Rodney King. (AP Photo/Paul Sakuma, File)
FILE - In this April 30, 1992 file photo, a Los Angeles police officer takes aim at a looter in a market at Alvarado and Beverly Boulevard in Los Angeles during the second night of rioting in the city. (AP Photo/John Gaps III, File)
FILE - A Korean shopping mall burns in Los Angeles, April 30, 1992 on the second day of rioting in the city following the acquittal of four police officers for the 1991 beating of motorist Rodney King. (AP Photo/Nick Ut, file)
President George H.W. Bush used the Insurrection Act to call in the National Guard after requests from Mayor Tom Bradley and Gov. Pete Wilson. After the current protests began Friday over Immigration and Customs Enforcement raids, President Donald Trump ordered the deployment of 4,100 National Guard troops and 700 Marines despite strident opposition from Mayor Karen Bass and Gov. Gavin Newsom.
Trump cited a legal provision to mobilize federal service members when there is “a rebellion or danger of a rebellion against the authority of the Government of the United States.” California Attorney General Rob Bonta filed a lawsuit Monday saying Trump had overstepped his authority. On Tuesday, Newsom filed an emergency motion in federal court to block the troops from assisting with immigration raids in Los Angeles.
Unlike the 1992 riots, protests have mainly been peaceful and been confined to a roughly five-block stretch of downtown LA, a tiny patch in the sprawling city of nearly 4 million people. No one has died. There's been vandalism and some cars set on fire but no homes or buildings have burned.
More than 100 people have been arrested over the past several days of protests. The vast majority of arrests were for failing to disperse, while a few others were for assault with a deadly weapon, looting, vandalism and attempted murder for tossing a Molotov cocktail.
Several officers have had minor injuries and protesters and some journalists have been struck by some of the more than 600 rubber bullets and other “less-lethal” munitions fired by police.
Outrage over the verdicts on April 29, 1992 led to nearly a week of widespread violence that was one of the deadliest riots in American history. Hundreds of businesses were looted. Entire blocks of homes and stores were torched. More than 60 people died in shootings and other violence, mostly in South Los Angeles, an area with a heavily Black population at the time.
The 1992 uprising took many by surprise, including the Los Angeles Police Department, but the King verdict was a catalyst for racial tensions that had been building in the city for years.
In addition to frustration with their treatment by police, some directed their anger at Korean merchants who owned many of the local stores. Black residents felt the owners treated them more like shoplifters than shoppers. As looting and fires spread toward Koreatown, some merchants protected their stores with shotguns and rifles.
FILE - In this April 29, 1992 file photo, demonstrators protest the verdict in the Rodney King beating case in front of the Los Angeles Police Department headquarters in Los Angeles. (AP Photo/Nick Ut, File)
FILE - A California Highway Patrol officer stands guard at Ninth Street and Vermont Avenue in Los Angeles as smoke rises from a fire further down the street, April 30, 1992. (AP Photo/David Longstreath, file)
FILE - In this April 30, 1992 file photo, smoke rises from a shopping center burned by rioters in Los Angeles after four police officers had been acquitted of the 1991 beating of motorist Rodney King. (AP Photo/Paul Sakuma, File)
FILE - In this April 30, 1992 file photo, a Los Angeles police officer takes aim at a looter in a market at Alvarado and Beverly Boulevard in Los Angeles during the second night of rioting in the city. (AP Photo/John Gaps III, File)
FILE - A Korean shopping mall burns in Los Angeles, April 30, 1992 on the second day of rioting in the city following the acquittal of four police officers for the 1991 beating of motorist Rodney King. (AP Photo/Nick Ut, file)
NEWARK, Del.--(BUSINESS WIRE)--Jan 15, 2026--
QPS Holdings, LLC (QPS), an award-winning contract research organization (CRO) focused on bioanalysis and clinical trials announces the successful implementation of Oracle Argus, a premier pharmacovigilance system designed to support comprehensive safety case management for clinical trials.
This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20260115711485/en/
The adoption of the Oracle Argus drug safety platform underscores QPS’s commitment to advancing patient safety, regulatory compliance, and operational excellence across its clients’ clinical drug development programs. Integrating this industry-standard safety platform strengthens QPS’ ability to capture, manage, and report adverse events in accordance with global regulatory requirements.
“Ensuring patient safety and data integrity is at the heart of what we do when conducting clinical trials,” said Derek Grimes, Executive Vice President of QPS. “Oracle Argus provides us with a robust, scalable solution to support the growing needs of our customer’s clinical trial portfolios and the evolving expectations of regulatory authorities worldwide.”
“Oracle Argus provides QPS Holdings, LLC with a trusted, globally recognized drug safety platform that supports compliance with stringent pharmacovigilance standards and regulations, while streamlining end-to-end safety operations and insights at scale,” said Seema Verma, executive vice president and general manager, Oracle Health and Life Sciences. “With our industry-leading solutions, QPS Holdings, LLC can further transform and elevate its safety case management for customers worldwide.”
The deployment of Oracle Argus will enable QPS to:
As the demand for innovative therapies continues to rise, CROs play a critical role in managing both development speed and patient safety. By leveraging the Oracle Argus platform, QPS is well-positioned to deliver on its mission to accelerate pharmaceutical breakthroughs across the globe by delivering custom-built research services.
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ABOUT QPS HOLDINGS, LLC
QPS is a global, full-service, GLP/GCP-compliant contract research organization (CRO) delivering the highest grade of discovery, bioanalysis, preclinical and clinical drug development services. Since 1995, QPS has grown from a small bioanalysis shop into a full-service CRO with 1,200+ employees in the US, Europe, Asia and India. Today, QPS offers expanded pharmaceutical contract R&D services with special expertise in pharmacology, DMPK, toxicology, bioanalysis, translational medicine, PBMC processing, central safety labs, clinical trials, and clinical research services. An award-winning leader focused on bioanalysis and clinical trials, QPS is known for proven quality standards, technical expertise, a flexible approach to research, client satisfaction, turnkey laboratories, Phase I/II clinical units, and multi-site clinical research services. For more information, visit http://www.qps.com or email info@qps.com.
ABOUT ORACLE ARGUS
Oracle Argus is an industry-leading, trusted solution for processing, analyzing, and reporting adverse event cases originating in pre-market and post-market drugs, biologics, vaccines, devices, and combination products. Oracle has been a Leader in the IDC MarketScape: Worldwide Life Science R&D Pharmacovigilance Technology Solutions and Consulting Services 2025 Vendor Assessment (doc # US53669225, July 2025). To learn more about Oracle’s pharmacovigilance portfolio visit: https://www.oracle.com/life-sciences/safety-solutions/argus-safety-case-management/. Trademarks: Oracle, Java, MySQL and NetSuite are registered trademarks of Oracle Corporation.
Derek Grimes, EVP, Global Head of Clinical Research at QPS Holdings, LLC.